JP7155110B2 - 免疫調節剤として有用なビアリール化合物 - Google Patents

免疫調節剤として有用なビアリール化合物 Download PDF

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JP7155110B2
JP7155110B2 JP2019511947A JP2019511947A JP7155110B2 JP 7155110 B2 JP7155110 B2 JP 7155110B2 JP 2019511947 A JP2019511947 A JP 2019511947A JP 2019511947 A JP2019511947 A JP 2019511947A JP 7155110 B2 JP7155110 B2 JP 7155110B2
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bis
biphenyl
oxy
dimethyl
diyl
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JP2019531274A (ja
JP2019531274A5 (enExample
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カプ－スン・イェウン
キャサリン・エイ・グラント－ヤング
ジュリアン・ジュー
マーク・ジー・ソールニアー
デイビッド・ビー・フレンネソン
デイビッド・アール・ラングレー
ピヤセナ・ヘワワサム
タオ・ワン
ジャン・ジョンシン
チャオシン・メン
リ－チアン・スン
エリック・マル
ポール・マイケル・スコラ
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Bristol Myers Squibb Co
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Bristol Myers Squibb Co
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
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