JP7068821B2 - 化学修飾を有するガイドｒｎａ - Google Patents

化学修飾を有するガイドｒｎａ Download PDF

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JP7068821B2
JP7068821B2 JP2017529610A JP2017529610A JP7068821B2 JP 7068821 B2 JP7068821 B2 JP 7068821B2 JP 2017529610 A JP2017529610 A JP 2017529610A JP 2017529610 A JP2017529610 A JP 2017529610A JP 7068821 B2 JP7068821 B2 JP 7068821B2
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certain embodiments
guide rna
nucleotide
sequence
synthetic
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JP2017537626A5 (enExample
JP2017537626A (ja
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ライアン，ダニエル・イー
デリンジャー，ダグラス・ジェイ
サンプソン，ジェフリー・アール
カイザー，ロバート
マイヤーソン，ジョエル
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Agilent Technologies Inc
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Agilent Technologies Inc
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    • C12N15/90—Stable introduction of foreign DNA into chromosome
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JP2017529610A 2014-12-03 2015-12-03 化学修飾を有するガイドｒｎａ Active JP7068821B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022020615A JP7579820B2 (ja) 2014-12-03 2022-02-14 化学修飾を有するガイドｒｎａ

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201462087211P 2014-12-03 2014-12-03
US62/087,211 2014-12-03
US201562146189P 2015-04-10 2015-04-10
US62/146,189 2015-04-10
US201562256095P 2015-11-16 2015-11-16
US62/256,095 2015-11-16
PCT/US2015/000143 WO2016089433A1 (en) 2014-12-03 2015-12-03 Guide rna with chemical modifications

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JP2022020615A Division JP7579820B2 (ja) 2014-12-03 2022-02-14 化学修飾を有するガイドｒｎａ

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JP2017537626A JP2017537626A (ja) 2017-12-21
JP2017537626A5 JP2017537626A5 (enExample) 2019-01-17
JP7068821B2 true JP7068821B2 (ja) 2022-05-17

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JP2022020615A Active JP7579820B2 (ja) 2014-12-03 2022-02-14 化学修飾を有するガイドｒｎａ

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US (5) US10900034B2 (enExample)
EP (2) EP3227447B1 (enExample)
JP (2) JP7068821B2 (enExample)
KR (2) KR102629128B1 (enExample)
CN (1) CN107250148B (enExample)
AU (1) AU2015355546B2 (enExample)
CA (1) CA2969619A1 (enExample)
WO (1) WO2016089433A1 (enExample)

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KR102888521B1 (ko) 2015-04-06 2025-11-19 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 Crispr/cas-매개 유전자 조절을 위한 화학적으로 변형된 가이드 rna
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