JP6833855B2 - 長期間経皮投与のためのシステムおよび方法 - Google Patents

長期間経皮投与のためのシステムおよび方法 Download PDF

Info

Publication number
JP6833855B2
JP6833855B2 JP2018534553A JP2018534553A JP6833855B2 JP 6833855 B2 JP6833855 B2 JP 6833855B2 JP 2018534553 A JP2018534553 A JP 2018534553A JP 2018534553 A JP2018534553 A JP 2018534553A JP 6833855 B2 JP6833855 B2 JP 6833855B2
Authority
JP
Japan
Prior art keywords
layer
mils
adhesive
mil
transdermal patch
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2018534553A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019504052A (ja
JP2019504052A5 (enExample
Inventor
ウン ス リ，
ウン ス リ，
アミット ケー． ジェイン，
アミット ケー． ジェイン，
パーミンダー シン，
パーミンダー シン，
Original Assignee
コリウム， インコーポレイテッド
コリウム， インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by コリウム， インコーポレイテッド, コリウム， インコーポレイテッド filed Critical コリウム， インコーポレイテッド
Publication of JP2019504052A publication Critical patent/JP2019504052A/ja
Publication of JP2019504052A5 publication Critical patent/JP2019504052A5/ja
Application granted granted Critical
Publication of JP6833855B2 publication Critical patent/JP6833855B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M35/00—Devices for applying media, e.g. remedies, on the human body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2018534553A 2015-12-30 2016-12-30 長期間経皮投与のためのシステムおよび方法 Active JP6833855B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562273288P 2015-12-30 2015-12-30
US62/273,288 2015-12-30
US201662367055P 2016-07-26 2016-07-26
US62/367,055 2016-07-26
PCT/US2016/069558 WO2017117554A1 (en) 2015-12-30 2016-12-30 Systems and methods for long term transdermal administration

Publications (3)

Publication Number Publication Date
JP2019504052A JP2019504052A (ja) 2019-02-14
JP2019504052A5 JP2019504052A5 (enExample) 2020-02-13
JP6833855B2 true JP6833855B2 (ja) 2021-02-24

Family

ID=57861282

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2018534553A Active JP6833855B2 (ja) 2015-12-30 2016-12-30 長期間経皮投与のためのシステムおよび方法

Country Status (11)

Country Link
US (6) US10835499B2 (enExample)
EP (1) EP3397250B1 (enExample)
JP (1) JP6833855B2 (enExample)
KR (1) KR102774558B1 (enExample)
CN (1) CN108697655B (enExample)
AU (2) AU2016381351B2 (enExample)
IL (2) IL303255A (enExample)
MX (1) MX2018008190A (enExample)
RU (1) RU2737464C2 (enExample)
SG (1) SG11201805570WA (enExample)
WO (1) WO2017117554A1 (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018511355A (ja) 2015-01-28 2018-04-26 クロノ セラピューティクス インコーポレイテッドＣｈｒｏｎｏ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． 薬剤送達方法及びシステム
AU2016228779A1 (en) 2015-03-12 2017-09-07 Chrono Therapeutics Inc. Craving input and support system
US10835499B2 (en) 2015-12-30 2020-11-17 Corium, Inc. Systems and methods for long term transdermal administration
CN109922796B (zh) 2016-06-23 2023-04-07 考里安有限责任公司 具有亲水和疏水域的粘合剂基质和治疗剂
JP7071330B2 (ja) 2016-07-27 2022-05-18 コリウム， インコーポレイテッド 炭酸水素ナトリウムのｉｎ ｓｉｔｕ変換で促進されたアミン薬物の経皮送達
KR102424270B1 (ko) * 2016-07-27 2022-07-25 코리움, 인크. 경구 전달과 생물학적으로 동등한 약물동역학을 가진 경피 전달 시스템
EP3490544A1 (en) 2016-07-27 2019-06-05 Corium International, Inc. Memantine transdermal delivery systems
WO2018129304A1 (en) 2017-01-06 2018-07-12 Chrono Therapeutics Inc. Transdermal drug delivery devices and methods
US11052054B2 (en) * 2017-04-19 2021-07-06 Inep Europe Sarl Method for manufacturing a transdermal device
US20180303764A1 (en) * 2017-04-19 2018-10-25 Inep Europe Sarl Method for manufacturing a transdermal device
EP3658127A1 (en) * 2017-07-26 2020-06-03 Corium, Inc. Transdermal delivery system with a microporous membrane having solvent-filled pores
WO2019126531A1 (en) 2017-12-20 2019-06-27 Corium, Inc. Transdermal adhesive composition comprising a volatile liquid therapeutic agent having low melting point
AU2019279884B2 (en) 2018-05-29 2025-01-30 Morningside Venture Investments Limited Drug delivery methods and systems
US20200121507A1 (en) 2018-10-18 2020-04-23 Moldex-Metric, Inc. Foam earplug with transdermal material
CN112206222A (zh) * 2018-11-09 2021-01-12 北京德默高科医药技术有限公司 含有布洛芬结构类似物的多层经皮给药系统
JP2022507660A (ja) 2018-11-16 2022-01-18 モーニングサイド ベンチャー インベストメンツ リミテッド 温度によって調節される経皮薬剤送達システム
CN114269330B (zh) * 2019-06-28 2025-07-22 帕斯帕特技术有限公司 透皮药物递送贴片、药物递送系统和药物递送方法
RU2705896C1 (ru) * 2019-07-26 2019-11-12 Артем Олегович Бахметьев Трансдермальный пластырь
US11471839B2 (en) * 2019-08-06 2022-10-18 Uop Llc High selectivity membranes for hydrogen sulfide and carbon dioxide removal from natural gas
WO2021211915A1 (en) * 2020-04-17 2021-10-21 University Of Connecticut Polycannabinoids, compounds, compositions and methods of use
US20210346207A1 (en) * 2020-05-11 2021-11-11 Marc Sheldon Stevens Four-way stretch therapeutic compress assembly, system, and method
US11596772B2 (en) * 2021-02-07 2023-03-07 Lumen Catheters, LLC Antimicrobial light-emitting percutaneous site dressing

Family Cites Families (265)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1880808A (en) 1927-03-28 1932-10-04 Eastman Kodak Co Process of making cellulose esters of carboxylic acids
US1683347A (en) 1927-08-25 1928-09-04 Eastman Kodak Co Process of making chloroform-soluble cellulose acetate
US1698049A (en) 1928-01-18 1929-01-08 Eastman Kodak Co Process of making cellulosic esters containing halogen-substituted fatty-acid groups
US1984147A (en) 1929-10-22 1934-12-11 Eastman Kodak Co Process for the production of cellulose esters and corresponding alkyl esters
US1880560A (en) 1929-12-14 1932-10-04 Eastman Kodak Co Process for the hydrolysis of cellulose acetate
US1943119A (en) 1929-12-17 1934-01-09 Westinghouse Electric & Mfg Co Circuitous elevator
US1939729A (en) 1930-01-29 1933-12-19 Thomas W Cohill Elevator system
US2129052A (en) 1936-02-04 1938-09-06 Eastman Kodak Co Hydrolyzed cellulose acetate
US3391142A (en) 1966-02-09 1968-07-02 Lilly Co Eli Adamantyl secondary amines
NL134681C (enExample) 1966-04-26
US3546141A (en) 1966-08-08 1970-12-08 Mc Donnell Douglas Corp Phosphorus-nitrogen polymers and process
US3493319A (en) 1967-05-26 1970-02-03 Us Agriculture Esterification of cellulosic textiles with unsaturated long chain fatty acids in the presence of trifluoroacetic anhydride using controlled cellulose-acid-anhydride ratios
US4004654A (en) 1971-07-07 1977-01-25 Trebron Holdings Limited Elevator structure supporting apparatus
NL7305644A (enExample) 1972-04-20 1973-10-23
DE2856393C2 (de) 1978-12-27 1983-04-28 Merz + Co GmbH & Co, 6000 Frankfurt Arzneimittel zur Behandlung von Morbus Parkinson
US4752478A (en) 1984-12-17 1988-06-21 Merck & Co., Inc. Transdermal system for timolol
DE3572485D1 (en) 1984-12-22 1989-09-28 Thomae Gmbh Dr K Tetrahydro-benzothiazoles, their production and their use as intermediates or drugs
FR2576888B1 (fr) 1985-02-05 1988-04-08 Otis Elevator Co Ascenseur transbordeur pour voies urbaines notamment
US4756710A (en) 1985-04-05 1988-07-12 Merck & Co., Inc. pH-Mediated drug delivery system
US4880633A (en) 1986-03-12 1989-11-14 Merck & Co., Inc. Transdermal drug delivery system
US4797284A (en) 1986-03-12 1989-01-10 Merck & Co., Inc. Transdermal drug delivery system
DE3634016A1 (de) * 1986-04-17 1987-10-29 Lohmann Gmbh & Co Kg Flaechenfoermiges therapeutisches system, verfahren zu seiner herstellung und seine verwendung
ATE71287T1 (de) 1986-06-13 1992-01-15 Alza Corp Aktivierung eines transdermalen drogenabgabesystems durch feuchtigkeit.
US5686489A (en) 1986-12-23 1997-11-11 Tristrata Technology, Inc. Alpha hydroxyacid esters for skin aging
US5071656A (en) 1987-03-05 1991-12-10 Alza Corporation Delayed onset transdermal delivery device
DE3714140A1 (de) * 1987-04-28 1988-11-10 Lohmann Therapie Syst Lts Wirkstoffhaltiges pflaster zur kontrollierten verabreichung von wirkstoffen an die haut, seine verwendung sowie verfahren zur gesteuerten verabreichung von wirkstoffen an die haut
US5538736A (en) * 1987-04-28 1996-07-23 Lts Lohmann Therapie-Systeme Gmbh Active substance-containing plaster for the controlled administration of active substances to the skin
US4787888A (en) 1987-06-01 1988-11-29 University Of Connecticut Disposable piezoelectric polymer bandage for percutaneous delivery of drugs and method for such percutaneous delivery (a)
FI95572C (fi) 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
US4781924A (en) 1987-11-09 1988-11-01 Alza Corporation Transdermal drug delivery device
US4837027A (en) 1987-11-09 1989-06-06 Alza Corporation Transdermal drug delivery device
US4849224A (en) 1987-11-12 1989-07-18 Theratech Inc. Device for administering an active agent to the skin or mucosa
US5656286A (en) 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5026556A (en) 1988-11-10 1991-06-25 Norwich Eaton Pharmaceuticals, Inc. Compositions for the transdermal delivery of pharmaceutical actives
CA2007181C (en) 1989-01-06 1998-11-24 Angelo Mario Morella Sustained release pharmaceutical composition
US5202128A (en) 1989-01-06 1993-04-13 F. H. Faulding & Co. Limited Sustained release pharmaceutical composition
DE10299048I2 (de) 1989-04-14 2006-07-13 Merz Pharma Gmbh & Co Kgaa Verwendung von Adamantan-Derivaten zur Pr{vention und Behandlung der cerebralen Isch{mie
DE3913734C2 (de) 1989-04-26 1998-08-20 Roehm Gmbh Verwendung einer wäßrigen Hauthaftkleberlösung zur Herstellung einer mit Wasser leicht abwaschbaren Klebschicht
ATE107517T1 (de) 1989-05-25 1994-07-15 Takeda Chemical Industries Ltd Transdermales therapeutisches mittel.
US5252588A (en) 1990-04-27 1993-10-12 Sekisui Kagaku Kogyo Kabushiki Kaisha Percutaneously absorbable crosslinked polyvinylpyrrolidone eperisone or tolperisone preparation
IE62597B1 (en) 1990-07-23 1995-02-08 Alza Corp Oral osmotic device for delivering nicotine
IT1243745B (it) 1990-10-17 1994-06-21 Vectorpharma Int Composizioni terapeutiche transdermali contenenti farmaco e/o agente promotore dell'assorbimento cutaneo supportato su particelle microporose e microsfere polimeriche e loro preparazione.
US5614560A (en) 1991-04-04 1997-03-25 Children's Medical Center Corporation Method of preventing NMDA receptor-mediated neuronal damage
US5123900A (en) * 1991-08-16 1992-06-23 Bertek, Inc. Moisture permeable double disk
US5246705A (en) 1992-04-08 1993-09-21 Cygnus Therapeutic System Occlusive, elastomeric backing materials in transdermal drug delivery systems, and associated methods of manufacture and use
JPH06199659A (ja) 1992-10-28 1994-07-19 Hisamitsu Pharmaceut Co Inc 経皮治療用装置
US5612411A (en) * 1992-11-18 1997-03-18 Kimberly-Clark Corporation Absorbent phycocolloids and a method for their manufacture
US5489624A (en) * 1992-12-01 1996-02-06 Minnesota Mining And Manufacturing Company Hydrophilic pressure sensitive adhesives
DE4310012A1 (de) 1993-03-27 1994-09-29 Roehm Gmbh Dermales therapeutisches System aus einer schmelzfähigen Poly(meth)acrylat-Mischung
JPH06321445A (ja) 1993-05-10 1994-11-22 Toshiba Corp エレベータ
US5424077A (en) 1993-07-13 1995-06-13 Church & Dwight Co., Inc. Co-micronized bicarbonate salt compositions
US5567489A (en) * 1993-09-16 1996-10-22 The Dow Chemical Company Multilayer halogen-free barrier film for ostomy and transdermal drug delivery applications
JP3135760B2 (ja) 1993-10-18 2001-02-19 株式会社竹中工務店 エレベータシステム
JPH07187525A (ja) 1993-11-18 1995-07-25 Masami Sakita 複数ばこエレベータシステム
ATE194281T1 (de) 1994-09-14 2000-07-15 Minnesota Mining & Mfg Matrix für transdermale wirkstofffreisetzung
US5557018A (en) 1994-09-27 1996-09-17 E. I. Du Pont De Nemours And Company Partially flourinated polymers and process therefor
US5635203A (en) 1994-09-29 1997-06-03 Alza Corporation Transdermal device having decreased delamination
CA2208132A1 (en) * 1994-12-21 1996-06-27 Theratech, Inc. Transdermal delivery system with adhesive overlay and peel seal disc
WO1996040087A2 (en) 1995-06-07 1996-12-19 Cygnus, Inc. Pressure sensitive acrylate adhesive composition cross-linked with aluminum acetylacetonate and containing a drug having a reactive aromatic hydroxyl group
US5785991A (en) * 1995-06-07 1998-07-28 Alza Corporation Skin permeation enhancer compositions comprising glycerol monolaurate and lauryl acetate
US5730900A (en) 1995-06-08 1998-03-24 Fuji Photo Film Co., Ltd. Film and process for preparation of the same and liquid crystal display
US5785153A (en) 1995-11-29 1998-07-28 Otis Elevator Company Synchronizing elevator arrival at a level of a building
US5601156A (en) 1995-11-29 1997-02-11 Otis Elevator Company Maintaining communications and power during transfer of horizontally moveable elevator cab
US5651426A (en) 1995-11-29 1997-07-29 Otis Elevator Company Synchronous elevator shuttle system
US5758748A (en) 1995-11-29 1998-06-02 Otis Elevator Company Synchronized off-shaft loading of elevator cabs
US5702720A (en) 1995-12-22 1997-12-30 Minnesota Mining And Manufacturing Company Transdermal device for the delivery of flurbiprofen
US6929801B2 (en) 1996-02-19 2005-08-16 Acrux Dds Pty Ltd Transdermal delivery of antiparkinson agents
TW513409B (en) 1996-06-07 2002-12-11 Eisai Co Ltd Polymorphs of donepezil hydrochloride
US5861586A (en) 1996-06-19 1999-01-19 Otis Elevator Company Horizontal and vertical passenger transport
US6512010B1 (en) 1996-07-15 2003-01-28 Alza Corporation Formulations for the administration of fluoxetine
US5752585A (en) 1996-07-25 1998-05-19 Otis Elevator Company Elevator shuttle with auxiliary elevators at terminals
US5924524A (en) 1996-07-25 1999-07-20 Otis Elevator Company Integrated, multi-level elevator shuttle
US5958919A (en) 1996-09-20 1999-09-28 Washington University Treatment of presymptomatic alzheimer's disease to prevent neuronal degeneration
ES2191834T3 (es) 1996-10-24 2003-09-16 Alza Corp Agentes que facilitan la permeacion y destinados para composiciones, dispositivos y procedimientos de aporte transdermico de medicamentos.
CN1174031A (zh) 1997-04-23 1998-02-25 谢先运 双氯芬酸钠透皮控释贴膏
US5866585A (en) 1997-05-22 1999-02-02 Synchroneuron, Llc Methods of treating tardive dyskinesia using NMDA receptor antagonists
US6174545B1 (en) 1997-07-01 2001-01-16 Alza Corporation Drug delivery devices and process of manufacture
US20040018241A1 (en) 1997-09-26 2004-01-29 Noven Pharmaceuticals, Inc. Bioadhesive compositions and methods for topical administration of active agents
US6193993B1 (en) 1998-03-03 2001-02-27 Eisai Co., Ltd. Suppository containing an antidementia medicament
JP4205778B2 (ja) 1998-04-17 2009-01-07 久光製薬株式会社 貼付製剤
DE19820999A1 (de) * 1998-05-11 1999-11-18 Lohmann Therapie Syst Lts Laminat zum Aufbringen auf einen Akzeptor
US6225348B1 (en) 1998-08-20 2001-05-01 Alfred W. Paulsen Method of treating macular degeneration with a prostaglandin derivative
US6248363B1 (en) 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US6383471B1 (en) 1999-04-06 2002-05-07 Lipocine, Inc. Compositions and methods for improved delivery of ionizable hydrophobic therapeutic agents
WO2001001962A1 (en) 1999-07-05 2001-01-11 Idea Ag. A method for the improvement of transport across adaptable semi-permeable barriers
US6562368B2 (en) 1999-12-16 2003-05-13 Dermatrends, Inc. Transdermal administration of oxybutynin using hydroxide-releasing agents as permeation enhancers
US20020192243A1 (en) 1999-12-16 2002-12-19 Tsung-Min Hsu Transdermal and topical administration of drugs for the treatment of Alzheimer's disease using basic enhancers
US6455066B1 (en) 2000-03-10 2002-09-24 Epicept Corporation Intradermal-penetration agents for topical local anesthetic administration
CA2415076C (en) 2000-07-07 2010-04-13 Mikhail M. Feldstein Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties
US7276249B2 (en) 2002-05-24 2007-10-02 Elan Pharma International, Ltd. Nanoparticulate fibrate formulations
JP3962684B2 (ja) 2000-11-06 2007-08-22 サムヤン コーポレイション 改善された水分吸収能および接着性を有する経皮投与剤
US20040028724A1 (en) 2000-11-07 2004-02-12 Takaaki Terahara Pharmaceutical preparation of percutaneous absorption type
JP4850346B2 (ja) 2001-03-15 2012-01-11 救急薬品工業株式会社 粘膜貼付剤
US20020182237A1 (en) 2001-03-22 2002-12-05 The Procter & Gamble Company Skin care compositions containing a sugar amine
ATE438418T1 (de) 2001-05-01 2009-08-15 Av Topchiev Inst Petrochemical Hydrogel-zusammensetzungen
US8206738B2 (en) 2001-05-01 2012-06-26 Corium International, Inc. Hydrogel compositions with an erodible backing member
US8541021B2 (en) 2001-05-01 2013-09-24 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions demonstrating phase separation on contact with aqueous media
US8840918B2 (en) 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
US20050215727A1 (en) 2001-05-01 2005-09-29 Corium Water-absorbent adhesive compositions and associated methods of manufacture and use
AU2002316053A1 (en) 2001-05-01 2002-11-11 A.V. Topchiev Institute Of Petrochemical Synthesis Two-phase, water-absorbent bioadhesive composition
US20050113510A1 (en) 2001-05-01 2005-05-26 Feldstein Mikhail M. Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components
US20040024028A1 (en) 2001-08-02 2004-02-05 Burton Steven L. Method for reducing or eliminating smoking
NL1018729C2 (nl) 2001-08-09 2003-02-11 Tms Internat B V Flexibele aansluitmodule en modulair systeem voor het meten en doorgeven van sensorsignalen.
CA2457011C (en) 2001-08-20 2012-04-24 Maiken Nedergaard Treatment of glial tumors with glutamate antagonists
NZ531404A (en) 2001-09-04 2006-03-31 Trommsdorff Gmbh & Co Plaster for the treatment of dysfunctions and disorders of nails, comprising sertaconazole
DE10159745A1 (de) 2001-12-05 2003-07-03 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit verbessertem Langzeittragekomfort
ITMI20012827A1 (it) 2001-12-28 2003-06-28 Fidia Farmaceutici Formulazioni adesive transdermiche di diclofenac sodico
US7273619B2 (en) 2002-01-17 2007-09-25 Samyang Corporation Transdermal composition of an antivomiting agent
US7217853B2 (en) 2002-05-24 2007-05-15 Corium International, Inc. Composition for cushions, wound dressings and other skin-contacting products
SG102714A1 (en) 2002-05-27 2004-03-26 Inventio Ag Elevator installation with several self-propelled cars and at least three elevator hoistways situated adjacently
CA2496798A1 (en) 2002-08-30 2004-03-11 Alza Corporation Embossable and writable multilaminate backing construction
CN100339070C (zh) 2002-10-24 2007-09-26 莫茨药物股份两合公司 包含1－氨基环己烷衍生物类和乙酰胆碱酯酶抑制剂类的药物组合物
CN1668521A (zh) 2002-11-26 2005-09-14 蒂森克虏伯电梯股份有限公司 用于控制电梯装置的方法及用于执行该方法的电梯装置
NZ541807A (en) 2003-02-21 2009-07-31 Bayer Schering Pharma Ag UV stable transdermal therapeutic plaster
US7294376B2 (en) 2003-08-26 2007-11-13 The Goodyear Tire & Rubber Company Tire with indicia
EP1526103B1 (de) 2003-10-09 2012-01-11 Inventio AG Aufzugsanlage mit mehrstöckigen Kabinen für den Zonenbetrieb in einem Gebäude
CA2538856C (en) 2003-10-10 2010-06-29 Antares Pharma Ipl Ag Transdermal pharmaceutical formulation for minimizing skin residues
EP1682060A1 (en) 2003-10-14 2006-07-26 Dermatrends, Inc. Enhancing transdermal administration of hydrophilic drugs
AU2004316119B2 (en) 2003-10-22 2008-04-24 Merz Pharma Gmbh & Co. Kgaa The use of 1-aminocyclohexane derivatives to modify deposition of fibrillogenic AB peptides in amyloidopathies
AU2004292966A1 (en) 2003-11-21 2005-06-09 Memory Pharmaceutical Corporation Compositions and methods of treatment using L-type calcium channel blockers and cholinesterase inhibitors
US7176185B2 (en) 2003-11-25 2007-02-13 Tsrl, Inc. Short peptide carrier system for cellular delivery of agent
KR20070007299A (ko) 2004-01-30 2007-01-15 코리움 인터네셔널, 인크. 활성제의 전달을 위한 급속 용해 필름
KR20070030178A (ko) 2004-02-17 2007-03-15 트랜스오랄 파마슈티칼스, 인코포레이티드 구강 점막을 가로지르는 수면제 전달용 조성물 및 이의사용 방법
DE102004010516A1 (de) 2004-03-04 2005-09-22 Bayer Technology Services Gmbh Verbessertes Verfahren zur zeitlichen Dosierung von Arzneistoffen
US7670838B2 (en) 2004-05-24 2010-03-02 The Board Of Trustees Of The Leland Stanford Junior University Coupling of excitation and neurogenesis in neural stem/progenitor cells
JPWO2005115355A1 (ja) 2004-05-28 2008-03-27 久光製薬株式会社 貼付製剤
TW200616608A (en) 2004-07-09 2006-06-01 Forest Laboratories Memantine as adjunctive treatment to atypical antipsychotics in schizophrenia patients
EP1616832A3 (de) 2004-07-15 2006-07-12 Inventio Ag Auzugsanlage mit mindestens drei nebeneinander angeordneten, vertikalen Aufzugsschächten und Verfahren zum Betreiben einer solchen Aufzugsanlage
TWI343357B (en) 2004-07-22 2011-06-11 Inventio Ag Elevator installation with individually movable elevator cars and method for operating such an elevator installation
MX2007001512A (es) 2004-08-05 2007-04-20 Corium Int Inc Composicion adhesiva.
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
ES2596809T3 (es) 2004-10-08 2017-01-12 Noven Pharmaceuticals, Inc. Dispositivo de administración transdérmica de fármacos que incluye un refuerzo oclusivo
ATE413166T1 (de) 2004-11-22 2008-11-15 Hisamitsu Pharmaceutical Co Transdermales pflaster enthaltend einen schmelzpunktsenkenden hilfsstoff
US8058291B2 (en) 2005-04-06 2011-11-15 Adamas Pharmaceuticals, Inc. Methods and compositions for the treatment of CNS-related conditions
US7619007B2 (en) 2004-11-23 2009-11-17 Adamas Pharmaceuticals, Inc. Method and composition for administering an NMDA receptor antagonist to a subject
AU2005319115B9 (en) 2004-12-21 2011-02-10 A.V. Topchiev Institute Of Petrochemical Synthesis Sustained release tooth whitening formulations and systems
US20060205822A1 (en) 2004-12-22 2006-09-14 Forest Laboratories, Inc. 1-Aminocyclohexane derivatives for the treatment of multiple sclerosis, emotional lability and pseudobulbar affect
MX2007007302A (es) 2005-01-11 2008-02-11 Teva Pharm Fine Chemicals Srl Proceso para la preparacion de clorhidrato de 1-amino-3,5-dimetiladamantano.
US20060163008A1 (en) 2005-01-24 2006-07-27 Michael Godwin Autonomous linear retarder/motor for safe operation of direct drive gearless, rope-less elevators
US20080138388A1 (en) 2005-02-04 2008-06-12 Hisamitsu Pharmaceutical Co., Inc. Transdermal Absorption Patch
US20060188558A1 (en) 2005-02-18 2006-08-24 Mylan Technologies, Inc. Transdermal systems having control delivery system
ATE524486T1 (de) 2005-04-27 2011-09-15 Sederma S A S Lys-thr-dipeptide und deren verwendung
US7888422B2 (en) 2005-11-09 2011-02-15 Mylan Technologies Inc. Long-wearing removable pressure sensitive adhesive
DK2001671T3 (da) 2006-03-28 2010-08-09 Amcor Flexibles Transpac B V B Halogenfri flerlagsfilm, som er impermeabel for aromaforbindelser
CN1895242B (zh) 2006-04-13 2011-08-31 沈阳药科大学 双氯芬酸盐的透皮贴剂及制备方法
IL175338A0 (en) 2006-05-01 2006-09-05 Biota Ltd Orally administrable films and preparation thereof
CN101460156B (zh) 2006-05-08 2011-06-08 帝国制药株式会社 抗痴呆药的经皮吸收制剂
US20070259029A1 (en) 2006-05-08 2007-11-08 Mcentire Edward Enns Water-dispersible patch containing an active agent for dermal delivery
JP5097359B2 (ja) 2006-05-09 2012-12-12 久光製薬株式会社 ドネペジル経皮吸収型製剤
WO2007132476A2 (en) 2006-05-15 2007-11-22 Matrix Laboratories Limited A process for the preparation of memantine hydrochloride
TW200815045A (en) 2006-06-29 2008-04-01 Jazz Pharmaceuticals Inc Pharmaceutical compositions of ropinirole and methods of use thereof
US9248104B2 (en) 2006-08-17 2016-02-02 Core Tech Solutions, Inc. Transdermal methods and systems for treating Alzheimer's disease
WO2008024408A2 (en) 2006-08-22 2008-02-28 Theraquest Biosciences, Inc. Pharmaceutical formulations of cannabinoids for application to the skin and method of use
AU2007325918B2 (en) 2006-11-03 2013-10-17 Durect Corporation Transdermal delivery systems comprising bupivacaine
US20080107719A1 (en) 2006-11-08 2008-05-08 Sukhon Likitlersuang Transdermal drug delivery system
KR101408488B1 (ko) 2006-12-01 2014-06-17 닛토덴코 가부시키가이샤 도네페질 함유 접착 제제의 경시적인 변색을 억제하는 방법
EP2638906A1 (en) 2006-12-01 2013-09-18 Nitto Denko Corporation Stabilized adhesive preparation containing donepezil
JP5237112B2 (ja) 2006-12-01 2013-07-17 日東電工株式会社 経皮吸収製剤
US20080226698A1 (en) 2007-03-16 2008-09-18 Mylan Technologies, Inc. Amorphous drug transdermal systems, manufacturing methods, and stabilization
JP2008259629A (ja) 2007-04-11 2008-10-30 Hakujuji Co Ltd 傷保護材
JP5403948B2 (ja) 2007-06-07 2014-01-29 久光製薬株式会社 メマンチン含有経皮吸収製剤
AU2008275101B2 (en) 2007-07-10 2014-08-21 Agile Therapeutics, Inc. Dermal delivery device with in situ seal
WO2009026135A2 (en) 2007-08-17 2009-02-26 Alza Corporation Controlled transdermal bisoprolol delivery system
US9017301B2 (en) 2007-09-04 2015-04-28 Mylan Technologies, Inc. Transdermal drug delivery systems comprising a coated release liner
CN100560157C (zh) * 2007-11-13 2009-11-18 重庆市生力医疗设备有限公司 超声波药贴
JP2009203213A (ja) 2008-02-28 2009-09-10 Kosumedei Seiyaku Kk 経皮吸収医薬組成物
DE102008013701A1 (de) 2008-03-11 2009-09-17 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System mit stabilisierter Membran
KR101454362B1 (ko) 2008-03-24 2014-10-23 아이큐어 주식회사 도네페질을 유효성분으로 함유하는 치매 치료용경피흡수제제
EP2111857A1 (de) 2008-04-25 2009-10-28 Acino AG Transdermales therapeutisches System zur Verabreichung von Fentanyl oder einem Analogstoff hiervon
US20090291127A1 (en) 2008-05-21 2009-11-26 Jianye Wen Transdermal anti-dementia active agent formulations and methods for using the same
EP2279739B2 (en) 2008-05-30 2018-02-28 Nitto Denko Corporation Donepezil-containing patch preparation and packaging thereof
US9636196B2 (en) * 2008-06-13 2017-05-02 ProBiora Health, LLC Use of hydrogen peroxide-producing bacteria for tooth whitening
TW201006625A (en) 2008-08-06 2010-02-16 Hou-Fei Hu Tool chuck for screwdriver
AR074062A1 (es) 2008-10-31 2010-12-22 Lexicon Pharmaceuticals Inc Agonistas del receptor s1p para el tratamiento de la malaria cerebral y forma farmaceutica
EP2196197A1 (en) 2008-12-15 2010-06-16 Bouty S.P.A. Antiviral patch
US20100178037A1 (en) 2009-01-12 2010-07-15 Te-Wei Chen Display apparatus, video generation apparatus, and method thereof
WO2010083035A2 (en) 2009-01-14 2010-07-22 Corium International, Inc. Transdermal administration of tamsulosin
CN101518599A (zh) * 2009-03-24 2009-09-02 沈阳药科大学 祖师麻提取物缓释贴剂及其制备方法
JP5758290B2 (ja) 2009-05-01 2015-08-05 久光製薬株式会社 経皮吸収型製剤
CN102630160B (zh) 2009-09-16 2014-05-07 株式会社三养生物制药 透皮递送系统、其制备方法以及使用所述系统的透皮递送方法
AU2010309030B2 (en) 2009-10-21 2013-10-31 Teikoku Seiyaku Co., Ltd. Transdermally absorbable donepezil-containing preparation
CN102048678A (zh) 2009-10-30 2011-05-11 北京隆旗生物科技有限公司 一种奥昔布宁的透皮吸收制剂及其制备方法与药物应用
GB0921481D0 (en) 2009-12-08 2010-01-20 Vectura Ltd Process and product
JP2012236773A (ja) 2009-12-16 2012-12-06 Goto Takeshi 抗認知症薬物の経皮吸収製剤
CA2785639A1 (en) 2009-12-30 2011-07-07 Novartis Ag Melt extruded nicotine thin strips
US20100178307A1 (en) 2010-01-13 2010-07-15 Jianye Wen Transdermal anti-dementia active agent formulations and methods for using the same
WO2011105486A1 (ja) 2010-02-24 2011-09-01 久光製薬株式会社 貼付剤
US20110244023A1 (en) 2010-03-30 2011-10-06 Phosphagenics Limited Transdermal delivery patch
ES2547888T3 (es) 2010-04-28 2015-10-09 Hisamitsu Pharmaceutical Co., Inc. Preparación que contiene donepezilo absorbible por vía transdérmica
US9012511B2 (en) 2010-05-19 2015-04-21 Alkermes Pharma Ireland Limited Nanoparticulate cinacalcet compositions
DE102010024105A1 (de) 2010-06-17 2011-12-22 Grünenthal GmbH Transdermale Verabreichung von Memantin
NZ605352A (en) 2010-06-30 2013-10-25 Nal Pharmaceuticals Ltd Process for producing glycosaminoglycans
US20140370076A1 (en) 2010-06-30 2014-12-18 Nal Pharmaceuticals, Ltd. Transdermal drug delivery system containing donepezil
PT2598119T (pt) 2010-07-29 2018-12-17 Allergan Inc Soluções de brimonidina e timolol isentas de conservantes
JP5711743B2 (ja) 2010-07-29 2015-05-07 久光製薬株式会社 医療用貼付剤
MX2013004123A (es) 2010-10-12 2013-12-16 Univ Johns Hopkins Composiciones antitusigenas que comprenden memantina.
WO2012057212A1 (ja) 2010-10-28 2012-05-03 久光製薬株式会社 経皮吸収型製剤
JP5699554B2 (ja) 2010-11-11 2015-04-15 富士通株式会社 ベクトル処理回路、命令発行制御方法、及びプロセッサシステム
CA2815898C (en) 2010-11-17 2018-12-18 Hexal Ag Transdermal therapeutic system comprising buprenorphine
WO2012084969A1 (en) 2010-12-22 2012-06-28 Hexal Ag Adhesive composition containing rotigotine and transdermal therapeutic system comprising the adhesive composition
WO2012089256A1 (en) 2010-12-29 2012-07-05 Pharmafilm S.R.L. Medicated patch for improved transdermal permeation of diclofenac diethylammonium
TWI433904B (zh) 2011-01-12 2014-04-11 Taiwan Biotech Co Ltd 多奈哌齊經皮貼片
CN102775476B (zh) 2011-05-12 2015-01-07 上海天伟生物制药有限公司 一种米卡芬净钠盐的制备方法
US8673338B2 (en) 2011-07-29 2014-03-18 Massachusetts Eye And Ear Infirmary Methods of delivering pharmaceutical agents
JP5820207B2 (ja) 2011-09-13 2015-11-24 日東電工株式会社 経皮吸収促進用組成物および貼付製剤
JP5808214B2 (ja) 2011-09-30 2015-11-10 株式会社トクヤマ 貼付剤
WO2013078608A1 (en) 2011-11-29 2013-06-06 Ziqiang Gu Donepezil pamoate and methods of making and using the same
BR112014014828A2 (pt) 2011-12-21 2017-06-13 3M Innovative Properties Co conjunto de emplastros adesivos com revestimento de sobreposição e sistema e método para a produção do mesmo
AU2013212005A1 (en) 2012-01-27 2014-07-31 Agile Therapeutics, Inc. Transdermal hormone delivery
KR101239150B1 (ko) 2012-02-28 2013-03-06 에스케이케미칼주식회사 도네페질-함유 경피흡수제제 및 그의 제조방법
US9408802B1 (en) 2012-03-22 2016-08-09 Prosolus, Inc. Seven day drug in adhesive transdermal delivery
US20140256690A1 (en) 2013-03-08 2014-09-11 Agile Therapeutics, Inc. Contraceptive method
US20140276479A1 (en) * 2013-03-14 2014-09-18 Noven Pharmaceuticals, Inc. Transdermal drug delivery system with overlay
WO2014174564A1 (ja) 2013-04-22 2014-10-30 祐徳薬品工業株式会社 メマンチン含有経皮吸収型貼付製剤
ITTV20130057A1 (it) 2013-04-23 2014-10-24 Tarcisio Scomparin "sistema elevatore e traslatore con struttura a portale che impiega cremagliere e piu' vie di corsa verticali ed orizzontali di almeno una cabina di trasporto di persone e cose per il superamento di ostacoli sopraelevato e non."
JP5415645B1 (ja) 2013-06-28 2014-02-12 久光製薬株式会社 貼付剤の製造方法、貼付剤及び包装体
EP3038608B1 (en) 2013-08-30 2018-01-03 3M Innovative Properties Company Estradiol containing transdermal drug delivery systems and compositions
WO2015042165A1 (en) 2013-09-17 2015-03-26 Corium International, Inc. Topical adhesive composition, and device, for improving aesthetic appearance of skin
RU2646512C2 (ru) 2013-10-07 2018-03-05 ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. Устройства для трансдермальной доставки дексмедетомидина и способы их применения
EP3054933A4 (en) 2013-10-11 2017-03-15 Teikoku Pharma USA, Inc. Topical sphingosine-1-phosphate receptor agonist formulations and methods of using the same
US11660344B2 (en) 2013-11-17 2023-05-30 Medrx Co., Ltd. Transdermal colloidal solution agent
CN106029541B (zh) 2013-12-05 2019-03-12 奥的斯电梯公司 具有一组不同数量的上下井道的高速无绳电梯
WO2015084371A1 (en) 2013-12-05 2015-06-11 Otis Elevator Company Ropeless high-rise elevator installation approach
KR101485822B1 (ko) 2014-01-22 2015-01-23 주식회사 대웅제약 도네페질 또는 그의 염을 함유하는 경피흡수제제
DE102014201804A1 (de) 2014-01-31 2015-08-06 Thyssenkrupp Elevator Ag Verfahren zum Betreiben eines Aufzugsystems
JP2015151370A (ja) 2014-02-14 2015-08-24 日東電工株式会社 貼付製剤
CN106103329A (zh) 2014-03-14 2016-11-09 奥的斯电梯公司 用于无绳电梯的稳健启动方法
WO2015200472A1 (en) 2014-06-24 2015-12-30 KAT Transdermals LLC Transdermal delivery system
US10071090B2 (en) 2014-07-18 2018-09-11 Buzzz Pharmaceuticals Limited Oxymorphone transdermal patch
CN106687138B (zh) 2014-09-03 2021-10-15 日东电工株式会社 包含双膦酸盐剂的细胞性免疫用疫苗药物组合物
WO2016046675A1 (en) 2014-09-28 2016-03-31 Mohan M Alapati Compositions and methods for the treatment of neurological diseases
DE102014220966A1 (de) 2014-10-16 2016-04-21 Thyssenkrupp Elevator Ag Verfahren zum Betreiben einer Transportanlage sowie entsprechende Transportanlage
CN106794964B (zh) 2014-10-16 2019-07-09 奥的斯电梯公司 用于具有磁性螺杆推进系统的电梯的横向中转站
PT3235494T (pt) 2014-12-18 2020-03-05 Icure Pharm Inc Preparação transdérmica contendo donepezilo como ingrediente ativo
CN107106723B (zh) * 2014-12-30 2020-10-23 3M创新有限公司 具有吸收性粘合剂密封层的负压伤口敷料
CN108135860A (zh) 2015-06-22 2018-06-08 考里安国际公司 包含难溶性治疗剂的透皮粘合剂组合物
US10017354B2 (en) 2015-07-10 2018-07-10 Otis Elevator Company Control system for multicar elevator system
US10370222B2 (en) 2015-07-16 2019-08-06 Otis Elevator Company Ropeless elevator system and a transfer system for a ropeless elevator system
CN112843023A (zh) 2015-07-27 2021-05-28 久光制药株式会社 含有阿塞那平的贴剂的制造方法
US10486940B2 (en) 2015-08-25 2019-11-26 Otis Elevator Company Alignment system for an elevator car
CN106477429B (zh) 2015-08-25 2020-08-21 奥的斯电梯公司 电梯轿厢引导机构
US10135299B2 (en) 2015-08-25 2018-11-20 Otis Elevator Company Elevator wireless power transfer system
ES2703398T3 (es) 2015-09-01 2019-03-08 Otis Elevator Co Comunicación inalámbrica de ascensor y sistema de transferencia de potencia
CN106477431B (zh) 2015-09-01 2020-01-21 奥的斯电梯公司 电梯轿厢的轿厢室隔离
US20170066623A1 (en) 2015-09-04 2017-03-09 Otis Elevator Company Ropeless elevator control system
CN106542392B (zh) 2015-09-16 2020-09-15 奥的斯电梯公司 电梯制动控制系统
AU2016231585B2 (en) 2015-09-25 2018-08-09 Otis Elevator Company Elevator component separation assurance system and method of operation
US10486939B2 (en) 2015-09-27 2019-11-26 Otis Elevator Company Breaking system for a hoisted structure and method of controlling braking a hoisted structure
US9598265B1 (en) 2015-09-28 2017-03-21 Smart Lifts, Llc Vertically and horizontally mobile elevator cabins
US10532908B2 (en) 2015-12-04 2020-01-14 Otis Elevator Company Thrust and moment control system for controlling linear motor alignment in an elevator system
US10835499B2 (en) * 2015-12-30 2020-11-17 Corium, Inc. Systems and methods for long term transdermal administration
US20170190544A1 (en) 2016-01-04 2017-07-06 Otis Elevator Company Lobby crowd control dispatching in mcrl system
CN105693556A (zh) 2016-03-01 2016-06-22 巴斯特医药科技（常州）有限公司 卡巴拉汀酒石酸盐的转化方法及其产物制成的贴片
CN109922796B (zh) 2016-06-23 2023-04-07 考里安有限责任公司 具有亲水和疏水域的粘合剂基质和治疗剂
JP7071330B2 (ja) 2016-07-27 2022-05-18 コリウム， インコーポレイテッド 炭酸水素ナトリウムのｉｎ ｓｉｔｕ変換で促進されたアミン薬物の経皮送達
EP3490544A1 (en) 2016-07-27 2019-06-05 Corium International, Inc. Memantine transdermal delivery systems
KR102424270B1 (ko) 2016-07-27 2022-07-25 코리움, 인크. 경구 전달과 생물학적으로 동등한 약물동역학을 가진 경피 전달 시스템
JP2018165790A (ja) 2017-03-28 2018-10-25 ブラザー工業株式会社 定着装置
EP3658127A1 (en) 2017-07-26 2020-06-03 Corium, Inc. Transdermal delivery system with a microporous membrane having solvent-filled pores
WO2019118782A1 (en) 2017-12-13 2019-06-20 Corium, Inc. Method for depot creation during transdermal drug delivery
WO2019126531A1 (en) 2017-12-20 2019-06-27 Corium, Inc. Transdermal adhesive composition comprising a volatile liquid therapeutic agent having low melting point
EP4362921A2 (en) 2021-06-28 2024-05-08 Corium, LLC Corona discharge treated transdermal delivery system
EP4362922A2 (en) 2021-06-28 2024-05-08 Corium, LLC Combination therapy treatment using transdermal delivery system
CN120513081A (zh) 2022-12-28 2025-08-19 考里安有限责任公司 制备透皮递送系统的方法
EP4642432A1 (en) 2022-12-28 2025-11-05 Corium, LLC Pre-mixing method of preparing transdermal delivery system

Also Published As

Publication number Publication date
RU2018127642A3 (enExample) 2020-05-13
WO2017117554A1 (en) 2017-07-06
RU2737464C2 (ru) 2020-11-30
CN108697655B (zh) 2021-12-10
SG11201805570WA (en) 2018-07-30
KR20180127315A (ko) 2018-11-28
IL260290B2 (en) 2023-11-01
IL303255A (en) 2023-07-01
US20170189534A1 (en) 2017-07-06
US20240108587A1 (en) 2024-04-04
EP3397250A1 (en) 2018-11-07
AU2016381351B2 (en) 2022-09-29
US12161767B2 (en) 2024-12-10
JP2019504052A (ja) 2019-02-14
IL260290B1 (en) 2023-07-01
EP3397250B1 (en) 2024-09-25
AU2022235539A1 (en) 2022-10-13
EP3397250C0 (en) 2024-09-25
KR102774558B1 (ko) 2025-03-04
MX2018008190A (es) 2018-11-12
US12168075B2 (en) 2024-12-17
RU2018127642A (ru) 2020-02-03
IL260290A (en) 2018-07-31
US20240091168A1 (en) 2024-03-21
US20170189348A1 (en) 2017-07-06
US20210023020A1 (en) 2021-01-28
US10835499B2 (en) 2020-11-17
US20210196650A1 (en) 2021-07-01
CA3010183A1 (en) 2017-07-06
AU2016381351A1 (en) 2018-07-19
US11648214B2 (en) 2023-05-16
US10966936B2 (en) 2021-04-06
US11679086B2 (en) 2023-06-20
CN108697655A (zh) 2018-10-23

Similar Documents

Publication Publication Date Title
US12161767B2 (en) Systems and methods for long term transdermal administration
KR101065000B1 (ko) 첩부제
WO2001066095A1 (fr) Timbre extensible
JP7625623B2 (ja) レボノルゲストレルおよびエチニルエストラジオールのための経皮的薬物送達システム
CA3010183C (en) Systems and methods for long term transdermal administration
TW201542249A (zh) 含畢索普洛（ｂｉｓｏｐｒｏｌｏｌ）之貼附製劑
JPH0630983A (ja) 貼付性に優れた貼付剤
CA3121252A1 (en) Transdermal therapeutic system with diffusion barrier
JP6892567B1 (ja) テープ剤
WO2021132501A1 (ja) テープ剤
HK40071716A (en) Tape preparation
JPWO2001066095A1 (ja) 伸縮性貼付剤

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20191223

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20191223

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20201211

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20210112

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20210203

R150 Certificate of patent or registration of utility model

Ref document number: 6833855

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

S531 Written request for registration of change of domicile

Free format text: JAPANESE INTERMEDIATE CODE: R313531

S533 Written request for registration of change of name

Free format text: JAPANESE INTERMEDIATE CODE: R313533

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250