ES2191834T3 - Agentes que facilitan la permeacion y destinados para composiciones, dispositivos y procedimientos de aporte transdermico de medicamentos. - Google Patents
Agentes que facilitan la permeacion y destinados para composiciones, dispositivos y procedimientos de aporte transdermico de medicamentos.Info
- Publication number
- ES2191834T3 ES2191834T3 ES97912815T ES97912815T ES2191834T3 ES 2191834 T3 ES2191834 T3 ES 2191834T3 ES 97912815 T ES97912815 T ES 97912815T ES 97912815 T ES97912815 T ES 97912815T ES 2191834 T3 ES2191834 T3 ES 2191834T3
- Authority
- ES
- Spain
- Prior art keywords
- drug
- transdermal
- permeation enhancer
- compositions
- permeation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
Abstract
LA PRESENTE INVENCION SE REFIERE A LA ADMINISTRACION TRANSDERMICA DE, POR LO MENOS, UN MEDICAMENTO ASOCIADO A UNA CANTIDAD INDICADA DE UN AGENTE QUE FACILITA LA PERMEACION Y QUE COMPRENDE MONOALQUILOETERES DE POLIETILENOGLICOL Y SUS ESTERES DE ACIDO ALQUILO O ARILO CARBOXILICO Y ESTERES DE CARBOXIMETILO. ESTA INVENCION SE REFIERE TAMBIEN A UN DISPOSITIVO DE APORTACION TRANSDERMICA DE UN MEDICAMENTO QUE COMPRENDE UNA MATRIZ ADAPTADA PARA COLOCARLA EN UNA POSICION DE TRANSMISION DE MEDICAMENTO Y DE AGENTE QUE FACILITA LA PERMEACION EN UN LUGAR DE LA PIEL. LA MATRIZ CONTIENE CANTIDADES SUFICIENTES DE AGENTE QUE FACILITAN LA PERMEACION, COMBINADAS CON UN MEDICAMENTO, PARA APORTAR CONTINUAMENTE UN MEDICAMENTO A LA CIRCULACION SANGUINEA GENERAL DE UN PACIENTE A UN RITMO EFICAZ DESDE EL PUNTO DE VISTA TERAPEUTICO. ESTA INVENCION SE REFIERE FINALMENTE A UNAS COMPOSICIONES Y PROCEDIMIENTOS QUE PERMITEN LA ADMINISTRACION TRANSDERMICA DE, COMO MINIMO, UN MEDICAMENTO COMBINADO CON UN AGENTE QUE FACILITA LA PERMEACION SEGUN LA PRESENTE INVENCION, SOLO O COMBINADO CON OTROS AGENTES DE ESTE TIPO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3042496P | 1996-10-24 | 1996-10-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2191834T3 true ES2191834T3 (es) | 2003-09-16 |
Family
ID=21854141
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES97912815T Expired - Lifetime ES2191834T3 (es) | 1996-10-24 | 1997-10-23 | Agentes que facilitan la permeacion y destinados para composiciones, dispositivos y procedimientos de aporte transdermico de medicamentos. |
Country Status (10)
Country | Link |
---|---|
US (1) | US6004578A (es) |
EP (1) | EP0934078B1 (es) |
JP (1) | JP2001502693A (es) |
AT (1) | ATE229817T1 (es) |
AU (1) | AU4990797A (es) |
CA (1) | CA2264687C (es) |
DE (1) | DE69718037T2 (es) |
DK (1) | DK0934078T3 (es) |
ES (1) | ES2191834T3 (es) |
WO (1) | WO1998017315A2 (es) |
Families Citing this family (110)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL140475A0 (en) * | 1998-06-25 | 2002-02-10 | Lavipharm Lab Inc | A device and method for the treatment of erectile dysfunction |
US6825234B2 (en) * | 1998-12-10 | 2004-11-30 | Nexmed (Holdings) , Inc. | Compositions and methods for amelioration of human female sexual dysfunction |
US20070191320A1 (en) * | 1998-12-10 | 2007-08-16 | Nexmed Holdings, Inc. | Methods of treatment for female sexual arousal disorder |
US6486207B2 (en) * | 1998-12-10 | 2002-11-26 | Nexmed (Holdings), Inc. | Compositions and methods for amelioration of human female sexual dysfunction |
ATE322889T1 (de) † | 1999-02-08 | 2006-04-15 | Alza Corp | Stabile nicht wässerige einphasige visköse vehikeln und formulierungen die diese vehikeln verwenden |
US7258869B1 (en) | 1999-02-08 | 2007-08-21 | Alza Corporation | Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle |
EP1153613B1 (en) * | 1999-02-19 | 2010-11-10 | Takeda Pharmaceutical Company Limited | Percutaneous absorption preparations of compound having angiotensin ii receptor antagonism |
EP1214944B1 (en) * | 1999-08-20 | 2009-09-23 | Takeda Pharmaceutical Company Limited | Composition for PERCUTANEOUS ABSORPTION with a compound having a melatonin receptor agonist activity |
US7179483B2 (en) | 2000-04-26 | 2007-02-20 | Watson Pharmaceuticals, Inc. | Compositions and methods for transdermal oxybutynin therapy |
USRE44145E1 (en) | 2000-07-07 | 2013-04-09 | A.V. Topchiev Institute Of Petrochemical Synthesis | Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties |
US20020119187A1 (en) * | 2000-09-29 | 2002-08-29 | Cantor Adam S. | Composition for the transdermal delivery of fentanyl |
WO2002054996A2 (en) * | 2000-10-23 | 2002-07-18 | Euro Celtique Sa | Terazosin transdermal device and methods |
US20050208117A1 (en) * | 2001-03-16 | 2005-09-22 | Venkatraman Subramanian S | Transdermal administration of fentanyl and analogs thereof |
CN100508974C (zh) * | 2001-03-16 | 2009-07-08 | 阿尔扎公司 | 施用芬太尼的经皮贴剂 |
US6521613B2 (en) | 2001-04-10 | 2003-02-18 | Allergan, Inc. | Lactam compounds for penetration enhancement |
US8840918B2 (en) | 2001-05-01 | 2014-09-23 | A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences | Hydrogel compositions for tooth whitening |
US8206738B2 (en) | 2001-05-01 | 2012-06-26 | Corium International, Inc. | Hydrogel compositions with an erodible backing member |
US20050113510A1 (en) | 2001-05-01 | 2005-05-26 | Feldstein Mikhail M. | Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components |
RU2276998C2 (ru) | 2001-05-01 | 2006-05-27 | Институт Нефтехимического Синтеза Имени А.В. Топчиева Российской Академии Наук | Гидрогелевые композиции |
US20050215727A1 (en) | 2001-05-01 | 2005-09-29 | Corium | Water-absorbent adhesive compositions and associated methods of manufacture and use |
RU2286801C2 (ru) | 2001-05-01 | 2006-11-10 | Институт Нефтехимического Синтеза Имени А.В. Топчиева Российской Академии Наук | Двухфазные биоадгезионные композиции, абсорбирующие воду |
US8541021B2 (en) | 2001-05-01 | 2013-09-24 | A.V. Topchiev Institute Of Petrochemical Synthesis | Hydrogel compositions demonstrating phase separation on contact with aqueous media |
DE10154324A1 (de) * | 2001-11-06 | 2003-08-07 | Merz Pharma Gmbh & Co Kgaa | Topisch applizierbare Zusammensetzungen mit externer Wirkstoffdepotbildung, deren Herstellung sowie deren Verwendung |
US20040033253A1 (en) * | 2002-02-19 | 2004-02-19 | Ihor Shevchuk | Acyl opioid antagonists |
US8440220B2 (en) | 2002-04-23 | 2013-05-14 | Durect Corporation | Transdermal analgesic systems with reduced abuse potential |
CN101455649B (zh) * | 2002-06-10 | 2014-02-26 | 欧洲凯尔特公司 | 防止所含活性剂被误用的经皮给药器的处置系统 |
ES2323127T3 (es) * | 2002-08-20 | 2009-07-07 | Euro-Celtique S.A. | Forma posologica transdermica que comprende un agente activo y una forma de sal y una forma de base libre de un antagonista. |
KR20050059072A (ko) * | 2002-08-30 | 2005-06-17 | 알자 코포레이션 | 엠보싱 및 기록가능한 다층 지지 구조물 |
US20040057907A1 (en) * | 2002-09-23 | 2004-03-25 | Leonard Mackles | Dri-nasal sprays |
IL152573A (en) * | 2002-10-31 | 2009-11-18 | Transpharma Medical Ltd | A system for the transmission through the skin of a medical preparation against vomiting and nausea |
IL152575A (en) * | 2002-10-31 | 2008-12-29 | Transpharma Medical Ltd | A skin-to-skin transmission system of water-insoluble drugs |
CA2453013C (en) * | 2002-12-13 | 2011-02-15 | Gary W. Cleary | Dermal, transdermal, mucosal or transmucosal ingredient delivery devices |
US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
US20040202708A1 (en) * | 2003-04-14 | 2004-10-14 | 3M Innovative Properties Company | Transdermal drug delivery device with translucent inorganic barrier layer |
AR047936A1 (es) | 2003-04-30 | 2006-03-15 | Purdue Pharma Ltd | Forma de dosificacion transdermica resistente a la manipulacion |
US8790689B2 (en) | 2003-04-30 | 2014-07-29 | Purdue Pharma L.P. | Tamper resistant transdermal dosage form |
US20040219198A1 (en) * | 2003-05-01 | 2004-11-04 | 3M Innovative Properties Company | Transdermal drug delivery device with multilayer backing |
US7563748B2 (en) * | 2003-06-23 | 2009-07-21 | Cognis Ip Management Gmbh | Alcohol alkoxylate carriers for pesticide active ingredients |
WO2005007020A2 (en) | 2003-07-03 | 2005-01-27 | Corium International, Inc. | Wound dressing, ingredient delivery device and iv hold-down, and method relating to same |
KR20060052931A (ko) | 2003-07-28 | 2006-05-19 | 알자 코포레이션 | 경피용 와파린-포함 전달 시스템 |
US20080020028A1 (en) * | 2003-08-20 | 2008-01-24 | Euro-Celtique S.A. | Transdermal dosage form comprising an active agent and a salt and a free-base form of an adverse agent |
WO2005044243A2 (en) | 2003-10-30 | 2005-05-19 | Alza Corporation | Transdermal analgesic systems having reduced abuse potential |
CN102764247B (zh) | 2004-01-30 | 2016-04-20 | 考里安国际公司 | 递送活性剂的快速溶解膜 |
AU2005271259B2 (en) | 2004-08-05 | 2012-01-19 | A.V. Topchiev Institute Of Petrochemical Synthesis | Adhesive composition |
WO2006023644A2 (en) * | 2004-08-20 | 2006-03-02 | 3M Innovative Properties Company | Transdermal drug delivery device with translucent protective film |
CN101044169A (zh) * | 2004-10-19 | 2007-09-26 | 3M创新有限公司 | 生产压敏粘合剂的方法 |
ATE471146T1 (de) | 2004-10-21 | 2010-07-15 | Durect Corp | Transdermale verabreichungssysteme |
US8252320B2 (en) | 2004-10-21 | 2012-08-28 | Durect Corporation | Transdermal delivery system for sufentanil |
WO2006083761A2 (en) | 2005-02-03 | 2006-08-10 | Alza Corporation | Solvent/polymer solutions as suspension vehicles |
US11246913B2 (en) | 2005-02-03 | 2022-02-15 | Intarcia Therapeutics, Inc. | Suspension formulation comprising an insulinotropic peptide |
US20060216350A1 (en) * | 2005-03-24 | 2006-09-28 | Dow Gordon J | Ganglionic blocking agents for the treatment of epithelial diseases |
PL1895994T3 (pl) * | 2005-05-13 | 2011-02-28 | Alza Corp | Wielowarstwowy system podawania leków z barierą zabezpieczającą przed wypływaniem materiału ze zbiornika |
JP2008543768A (ja) | 2005-06-10 | 2008-12-04 | スリーエム イノベイティブ プロパティズ カンパニー | 接着性積層体区画を取り扱うための方法 |
WO2007035942A2 (en) * | 2005-09-23 | 2007-03-29 | Alza Corporation | Transdermal risperidone delivery system |
US8383149B2 (en) | 2005-09-23 | 2013-02-26 | Alza Corporation | High enhancer-loading polyacrylate formulation for transdermal applications |
WO2007035941A2 (en) * | 2005-09-23 | 2007-03-29 | Alza Corporation | Transdermal galantamine delivery system |
WO2007035940A2 (en) * | 2005-09-23 | 2007-03-29 | Alza Corporation | Transdermal norelgestromin delivery system |
US20070087055A1 (en) * | 2005-10-14 | 2007-04-19 | David Jan | Directly compressible extended release alprazolam formulation |
WO2007046102A2 (en) | 2005-10-19 | 2007-04-26 | Menni Menashe Zinger | Methods for the treatment of hyperhidrosis |
JP5143131B2 (ja) | 2006-05-30 | 2013-02-13 | インターシア セラピューティクス,インコーポレイティド | 浸透圧送出システムの二片構成内部チャネル型の流れモジュレータ |
US20070278289A1 (en) * | 2006-05-31 | 2007-12-06 | Toshiba Tec Kabushiki Kaisha | Payment adjusting apparatus and program therefor |
PL2359808T3 (pl) | 2006-08-09 | 2013-10-31 | Intarcia Therapeutics Inc | Osmotyczne systemy dostawcze i zespoły tłokowe |
WO2008116004A2 (en) | 2007-03-19 | 2008-09-25 | Vita Sciences, Llc | Transdermal patch and method for delivery of vitamin b12 |
MX2009011123A (es) | 2007-04-23 | 2009-11-02 | Intarcia Therapeutics Inc | Formulaciones de suspensiones de peptidos insulinotropicos y sus usos. |
US9814422B2 (en) | 2007-08-06 | 2017-11-14 | The Regents Of The University Of California | Compositions for solubilizing cells and/or tissue |
WO2009048681A2 (en) | 2007-08-06 | 2009-04-16 | The Regents Of The University Of California | Methods of tissue-based diagnosis |
RU2499583C2 (ru) * | 2007-10-15 | 2013-11-27 | Алза Корпорейшн | Заместительное трансдермальное введение фентанила один раз в день |
EP2240155B1 (en) | 2008-02-13 | 2012-06-06 | Intarcia Therapeutics, Inc | Devices, formulations, and methods for delivery of multiple beneficial agents |
CN102164601A (zh) * | 2008-09-30 | 2011-08-24 | 帝国制药美国公司 | 经皮延长给药多奈哌齐组合物及其使用方法 |
WO2010083035A2 (en) * | 2009-01-14 | 2010-07-22 | Corium International, Inc. | Transdermal administration of tamsulosin |
EP3620154A1 (en) | 2009-02-06 | 2020-03-11 | University Of Southern California | Therapeutic compositions comprising monoterpenes |
NZ598686A (en) | 2009-09-28 | 2014-05-30 | Intarcia Therapeutics Inc | Rapid establishment and/or termination of substantial steady-state drug delivery |
CN102639322B (zh) | 2009-11-30 | 2015-11-25 | 3M创新有限公司 | 适形的阻隔片、方法及装置 |
EP3769754A1 (en) | 2010-03-03 | 2021-01-27 | Neonc Technologies, Inc. | Pharmaceutical compositions comprising monoterpenes |
US20120208755A1 (en) | 2011-02-16 | 2012-08-16 | Intarcia Therapeutics, Inc. | Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers |
CA2831308A1 (en) * | 2011-03-31 | 2012-10-04 | Sk Biopharmaceuticals Co., Ltd. | Intranasal benzodiazepine pharmaceutical compositions |
US9849270B2 (en) | 2011-12-16 | 2017-12-26 | 3M Innovative Properties Company | Foldable adhesive composite dressing |
BR112014014828A2 (pt) | 2011-12-21 | 2017-06-13 | 3M Innovative Properties Co | conjunto de emplastros adesivos com revestimento de sobreposição e sistema e método para a produção do mesmo |
US9144671B2 (en) | 2011-12-21 | 2015-09-29 | 3M Innovative Properties Company | Transdermal adhesive patch assembly with removable microneedle array and method of using same |
MX369625B (es) * | 2012-05-16 | 2019-11-14 | Univ California | Composiciones para solubilizar celulas y/o tejido. |
WO2014058746A1 (en) | 2012-10-10 | 2014-04-17 | 3M Innovative Properties Company | Force-controlled applicator for applying a microneedle device to skin |
WO2014078545A1 (en) | 2012-11-16 | 2014-05-22 | 3M Innovative Properties Company | Force-controlled applicator for applying a microneedle device to skin |
KR101712413B1 (ko) | 2013-03-22 | 2017-03-06 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 카운터 조립체를 포함하는 마이크로니들 어플리케이터 |
CN105283216B (zh) | 2013-05-31 | 2018-01-26 | 3M创新有限公司 | 包括倒置致动器的微针注入设备 |
SG11201509810TA (en) | 2013-05-31 | 2015-12-30 | 3M Innovative Properties Co | Microneedle injection and infusion apparatus and method of using same |
CN105246541B (zh) | 2013-05-31 | 2018-01-16 | 3M创新有限公司 | 包括双覆盖件的微针注射设备 |
CN105491982B (zh) | 2013-08-12 | 2019-09-10 | 3M创新有限公司 | 用于增强透皮递送的肽 |
US9889085B1 (en) | 2014-09-30 | 2018-02-13 | Intarcia Therapeutics, Inc. | Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c |
EP3020398A1 (en) | 2014-11-17 | 2016-05-18 | Nitto Denko Corporation | Compounds and formulations for reducing scarring |
CN107107598B (zh) | 2014-12-18 | 2019-11-22 | 3M创新有限公司 | 处理粘合层合物贴剂的方法 |
AU2016270984B2 (en) | 2015-06-03 | 2021-02-25 | Intarcia Therapeutics, Inc. | Implant placement and removal systems |
WO2017024282A1 (en) | 2015-08-05 | 2017-02-09 | Children's Medical Center Corporation | Compositions with permeation enhancers for drug delivery |
WO2017136303A1 (en) | 2016-02-05 | 2017-08-10 | 3M Innovative Properties Company | Transdermal drug delivery systems with fluorosilicone release liners |
JP6835707B2 (ja) * | 2016-04-05 | 2021-02-24 | 株式会社Moresco | オキサ酸化合物 |
CN109310743A (zh) | 2016-05-16 | 2019-02-05 | 因塔西亚制药公司 | 胰高血糖素受体选择性多肽及其使用方法 |
USD860451S1 (en) | 2016-06-02 | 2019-09-17 | Intarcia Therapeutics, Inc. | Implant removal tool |
USD840030S1 (en) | 2016-06-02 | 2019-02-05 | Intarcia Therapeutics, Inc. | Implant placement guide |
CN109922796B (zh) | 2016-06-23 | 2023-04-07 | 考里安有限责任公司 | 具有亲水和疏水域的粘合剂基质和治疗剂 |
US20180028461A1 (en) | 2016-07-27 | 2018-02-01 | Corium International, Inc. | Transdermal delivery systems with pharmacokinetics bioequivalent to oral delivery |
US9993466B2 (en) | 2016-07-27 | 2018-06-12 | Corium International, Inc. | Donepezil transdermal delivery system |
EP3490544A1 (en) | 2016-07-27 | 2019-06-05 | Corium International, Inc. | Memantine transdermal delivery systems |
EP3287462A1 (en) | 2016-08-25 | 2018-02-28 | Nitto Denko Corporation | Isosorbide derivatives to treat bacterial biofilms |
EP3565580B1 (en) | 2017-01-03 | 2024-03-06 | i2o Therapeutics, Inc. | Continuous administration of exenatide and co-adminstration of acetaminophen, ethinylestradiol or levonorgestrel |
JP6799138B2 (ja) | 2017-03-03 | 2020-12-09 | 株式会社Moresco | 吸収促進剤およびその利用 |
US11173132B2 (en) | 2017-12-20 | 2021-11-16 | Corium, Inc. | Transdermal adhesive composition comprising a volatile liquid therapeutic agent having low melting point |
CA3225993A1 (en) | 2018-02-08 | 2019-08-15 | University Of Southern California | The use of monoterpene, sesquiterpene, or their derivatives to permeabilize the blood brain barrier |
CA3095873A1 (en) * | 2018-04-05 | 2019-10-10 | Steven Robert ERBST | Therapeutic elastic bandage for modulating the endocannabinoid system |
WO2019217536A1 (en) * | 2018-05-08 | 2019-11-14 | University Of Connecticut | Long-acting local anesthetic formulation |
USD933219S1 (en) | 2018-07-13 | 2021-10-12 | Intarcia Therapeutics, Inc. | Implant removal tool and assembly |
WO2021022033A1 (en) * | 2019-07-30 | 2021-02-04 | Leung Kai P | Layered composite for scar treatment and prevention |
Family Cites Families (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1011949A (en) * | 1964-10-27 | 1965-12-01 | Vacu Blast Ltd | Centrifugal wheel blasting machine |
US3527864A (en) * | 1966-11-18 | 1970-09-08 | Procter & Gamble | Compositions for topical application to animal tissue and method of enhancing penetration thereof |
US3472931A (en) * | 1969-01-17 | 1969-10-14 | Foster Milburn Co | Percutaneous absorption with lower alkyl amides |
US3797494A (en) * | 1969-04-01 | 1974-03-19 | Alza Corp | Bandage for the administration of drug by controlled metering through microporous materials |
US3598123A (en) * | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
US3731663A (en) * | 1971-01-08 | 1973-05-08 | Hollins J R | Vehicle engine fuel control accelerator override |
US3903256A (en) * | 1972-02-07 | 1975-09-02 | Procter & Gamble | Compositions for topical application of animal tissue and method of enhancing penetration thereof |
US3896238A (en) * | 1972-04-05 | 1975-07-22 | Procter & Gamble | Dermatological compositions |
US3952099A (en) * | 1973-03-13 | 1976-04-20 | The Procter & Gamble Company | Dermatological compositions |
US4046886A (en) * | 1975-01-17 | 1977-09-06 | The Procter & Gamble Company | Dermatological compositions |
US4144317A (en) * | 1975-05-30 | 1979-03-13 | Alza Corporation | Device consisting of copolymer having acetoxy groups for delivering drugs |
US4130667A (en) * | 1976-01-12 | 1978-12-19 | The Procter & Gamble Company | Dermatological compositions |
US4335115A (en) * | 1976-11-01 | 1982-06-15 | The Procter & Gamble Company | Anti-acne composition |
US4299826A (en) * | 1979-10-12 | 1981-11-10 | The Procter & Gamble Company | Anti-acne composition |
US4286592A (en) * | 1980-02-04 | 1981-09-01 | Alza Corporation | Therapeutic system for administering drugs to the skin |
US4314557A (en) * | 1980-05-19 | 1982-02-09 | Alza Corporation | Dissolution controlled active agent dispenser |
FR2495934A1 (fr) * | 1980-12-15 | 1982-06-18 | Cird | Composition pour le traitement du psoriasis a base d'une dihydroxy-1,8 anthrone-9 substituee en position 10 |
US4379454A (en) * | 1981-02-17 | 1983-04-12 | Alza Corporation | Dosage for coadministering drug and percutaneous absorption enhancer |
US4343798A (en) * | 1981-06-23 | 1982-08-10 | The Procter & Gamble Company | Topical antimicrobial anti-inflammatory compositions |
US4849226A (en) * | 1981-06-29 | 1989-07-18 | Alza Corporation | Method for increasing oxygen supply by administering vasodilator |
US4435180A (en) * | 1982-05-25 | 1984-03-06 | Alza Corporation | Elastomeric active agent delivery system and method of use |
US4559222A (en) * | 1983-05-04 | 1985-12-17 | Alza Corporation | Matrix composition for transdermal therapeutic system |
US4573999A (en) * | 1983-10-14 | 1986-03-04 | Netto Daniel J | Human breast prosthesis |
US4704282A (en) * | 1984-06-29 | 1987-11-03 | Alza Corporation | Transdermal therapeutic system having improved delivery characteristics |
US4568343A (en) * | 1984-10-09 | 1986-02-04 | Alza Corporation | Skin permeation enhancer compositions |
US4645502A (en) * | 1985-05-03 | 1987-02-24 | Alza Corporation | Transdermal delivery of highly ionized fat insoluble drugs |
US4908027A (en) * | 1986-09-12 | 1990-03-13 | Alza Corporation | Subsaturated transdermal therapeutic system having improved release characteristics |
US4863970A (en) * | 1986-11-14 | 1989-09-05 | Theratech, Inc. | Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols |
US4746515A (en) * | 1987-02-26 | 1988-05-24 | Alza Corporation | Skin permeation enhancer compositions using glycerol monolaurate |
US4865848A (en) * | 1987-02-26 | 1989-09-12 | Alza Corporation | Skin permeation enhancer compositions using sucrose esters |
US4940586A (en) * | 1987-02-26 | 1990-07-10 | Alza Corporation | Skin permeation enhancer compositions using sucrose esters |
US4788062A (en) * | 1987-02-26 | 1988-11-29 | Alza Corporation | Transdermal administration of progesterone, estradiol esters, and mixtures thereof |
US4816258A (en) * | 1987-02-26 | 1989-03-28 | Alza Corporation | Transdermal contraceptive formulations |
US4900555A (en) * | 1987-02-26 | 1990-02-13 | Alza Corporation | Skin permeation enhancer compositions using sucrose esters |
US4764379A (en) * | 1987-08-24 | 1988-08-16 | Alza Corporation | Transdermal drug delivery device with dual permeation enhancers |
US4820720A (en) * | 1987-08-24 | 1989-04-11 | Alza Corporation | Transdermal drug composition with dual permeation enhancers |
US4943435A (en) * | 1987-10-05 | 1990-07-24 | Pharmetrix Corporation | Prolonged activity nicotine patch |
US4863738A (en) * | 1987-11-23 | 1989-09-05 | Alza Corporation | Skin permeation enhancer compositions using glycerol monooleate |
US5378730A (en) * | 1988-06-09 | 1995-01-03 | Alza Corporation | Permeation enhancer comprising ethanol and monoglycerides |
US5004610A (en) * | 1988-06-14 | 1991-04-02 | Alza Corporation | Subsaturated nicotine transdermal therapeutic system |
US5053327A (en) * | 1988-09-20 | 1991-10-01 | The United States Of America As Represented By The Secretary Of Agriculture | High affinity monoclonal antibodies to bowman-birk inhibitor and immunoassay methods |
US4973468A (en) * | 1989-03-22 | 1990-11-27 | Cygnus Research Corporation | Skin permeation enhancer compositions |
US5059426A (en) * | 1989-03-22 | 1991-10-22 | Cygnus Therapeutic Systems | Skin permeation enhancer compositions, and methods and transdermal systems associated therewith |
JP2820306B2 (ja) * | 1990-02-27 | 1998-11-05 | 積水化学工業株式会社 | 経皮吸収製剤 |
US5314694A (en) * | 1990-10-29 | 1994-05-24 | Alza Corporation | Transdermal formulations, methods and devices |
DE4115849A1 (de) * | 1991-05-15 | 1992-11-19 | Lohmann Therapie Syst Lts | Penetrationsfoerdernde substanz |
KR950701516A (ko) * | 1992-05-13 | 1995-04-28 | 에드워드 엘. 만델 | 옥시부티닌의 경피 투여(Transdermal Administration of Oxybutynin) |
EP0721348B1 (en) * | 1993-09-29 | 1999-09-01 | Alza Corporation | Monoglyceride/lactate ester permeation enhancer |
WO1996019976A1 (en) * | 1994-12-24 | 1996-07-04 | Pacific Corporation | Medicinal patches for percutaneous administration |
US6572879B1 (en) * | 1995-06-07 | 2003-06-03 | Alza Corporation | Formulations for transdermal delivery of pergolide |
-
1997
- 1997-10-23 EP EP97912815A patent/EP0934078B1/en not_active Expired - Lifetime
- 1997-10-23 ES ES97912815T patent/ES2191834T3/es not_active Expired - Lifetime
- 1997-10-23 AU AU49907/97A patent/AU4990797A/en not_active Abandoned
- 1997-10-23 CA CA002264687A patent/CA2264687C/en not_active Expired - Fee Related
- 1997-10-23 WO PCT/US1997/018956 patent/WO1998017315A2/en active IP Right Grant
- 1997-10-23 AT AT97912815T patent/ATE229817T1/de not_active IP Right Cessation
- 1997-10-23 US US08/956,379 patent/US6004578A/en not_active Expired - Lifetime
- 1997-10-23 DK DK97912815T patent/DK0934078T3/da active
- 1997-10-23 DE DE69718037T patent/DE69718037T2/de not_active Expired - Fee Related
- 1997-10-23 JP JP10519563A patent/JP2001502693A/ja not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
US6004578A (en) | 1999-12-21 |
WO1998017315A3 (en) | 1998-07-02 |
EP0934078A2 (en) | 1999-08-11 |
DE69718037T2 (de) | 2003-07-10 |
DK0934078T3 (da) | 2003-04-14 |
CA2264687C (en) | 2006-04-25 |
JP2001502693A (ja) | 2001-02-27 |
CA2264687A1 (en) | 1998-04-30 |
DE69718037D1 (de) | 2003-01-30 |
EP0934078B1 (en) | 2002-12-18 |
ATE229817T1 (de) | 2003-01-15 |
AU4990797A (en) | 1998-05-15 |
WO1998017315A2 (en) | 1998-04-30 |
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