JP6629716B2 - タウ発現を調節するための組成物および方法 - Google Patents

タウ発現を調節するための組成物および方法 Download PDF

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JP6629716B2
JP6629716B2 JP2016503214A JP2016503214A JP6629716B2 JP 6629716 B2 JP6629716 B2 JP 6629716B2 JP 2016503214 A JP2016503214 A JP 2016503214A JP 2016503214 A JP2016503214 A JP 2016503214A JP 6629716 B2 JP6629716 B2 JP 6629716B2
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modified
certain embodiments
compound
tau
oligonucleotide
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JP2016513976A (ja
JP2016513976A5 (enExample
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リゴ，フランク
ベネット，シー・フランク
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Ionis Pharmaceuticals Inc
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JP2016503214A 2013-03-14 2014-03-14 タウ発現を調節するための組成物および方法 Active JP6629716B2 (ja)

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US201361785177P 2013-03-14 2013-03-14
US61/785,177 2013-03-14
US201461943931P 2014-02-24 2014-02-24
US61/943,931 2014-02-24
PCT/US2014/029752 WO2014153236A1 (en) 2013-03-14 2014-03-14 Compositions and methods for modulating tau expression

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JP2016513976A5 JP2016513976A5 (enExample) 2017-04-20
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KR (1) KR20150130430A (enExample)
CN (2) CN111254145A (enExample)
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TW202246503A (zh) 2013-07-19 2022-12-01 美商百健Ｍａ公司 用於調節τ蛋白表現之組合物
JP6772156B2 (ja) 2015-02-04 2020-10-21 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ 治療用分子を選択する方法
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JOP20200228A1 (ar) * 2015-12-21 2017-06-16 Novartis Ag تركيبات وطرق لخفض تعبير البروتين tau
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JP7292204B2 (ja) * 2016-12-01 2023-06-16 サンガモ セラピューティクス， インコーポレイテッド タウモジュレーターならびにその送達のための方法および組成物
CN111868068A (zh) 2018-03-13 2020-10-30 詹森药业有限公司 用于在tau蛋白病变治疗中使用的经修饰的寡核苷酸
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