EA202091865A1 - Композиции и способы для снижения экспрессии tau - Google Patents

Композиции и способы для снижения экспрессии tau

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Publication number
EA202091865A1
EA202091865A1 EA202091865A EA202091865A EA202091865A1 EA 202091865 A1 EA202091865 A1 EA 202091865A1 EA 202091865 A EA202091865 A EA 202091865A EA 202091865 A EA202091865 A EA 202091865A EA 202091865 A1 EA202091865 A1 EA 202091865A1
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Prior art keywords
compositions
methods
tau
expression
reducing
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EA202091865A
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English (en)
Inventor
Мануэла Полидоро Офенгейм
Ян Вайлер
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Новартис Аг
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Application filed by Новартис Аг filed Critical Новартис Аг
Publication of EA202091865A1 publication Critical patent/EA202091865A1/ru

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Abstract

Настоящее изобретение относится к композициям и к способам для снижения уровня экспрессии мРНК и белка tau. Эти композиции и способы могут быть применены для лечения tau-ассоциированных заболеваний и расстройств.
EA202091865A 2015-12-21 2016-12-19 Композиции и способы для снижения экспрессии tau EA202091865A1 (ru)

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US201562270165P 2015-12-21 2015-12-21

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EA202091865A1 true EA202091865A1 (ru) 2021-01-29

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EA201891468A EA036417B1 (ru) 2015-12-21 2016-12-19 Композиции и способы для снижения экспрессии tau
EA202091865A EA202091865A1 (ru) 2015-12-21 2016-12-19 Композиции и способы для снижения экспрессии tau

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US (2) US11473083B2 (ru)
EP (1) EP3394259B1 (ru)
JP (3) JP7027328B2 (ru)
KR (1) KR20180089517A (ru)
CN (2) CN116218848A (ru)
AR (1) AR107579A1 (ru)
AU (2) AU2016376034B2 (ru)
BR (1) BR112018012304A2 (ru)
CA (1) CA3008094A1 (ru)
CL (3) CL2018001652A1 (ru)
CO (1) CO2018006297A2 (ru)
CR (1) CR20200609A (ru)
CU (1) CU24574B1 (ru)
DO (1) DOP2018000151A (ru)
EA (2) EA036417B1 (ru)
EC (1) ECSP18050575A (ru)
HK (1) HK1254822A1 (ru)
IL (3) IL296844B2 (ru)
JO (2) JOP20200228A1 (ru)
MX (2) MX2018007726A (ru)
MY (1) MY191737A (ru)
PE (1) PE20181448A1 (ru)
PH (1) PH12018501207A1 (ru)
RU (1) RU2747734C2 (ru)
SA (1) SA518391831B1 (ru)
SG (2) SG10201913434PA (ru)
SV (1) SV2018005714A (ru)
TW (1) TWI787163B (ru)
UY (1) UY37038A (ru)
WO (1) WO2017109679A1 (ru)

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