JP6359520B2 - Ｂ細胞成熟抗原を標的指向するキメラ抗原受容体 - Google Patents

Ｂ細胞成熟抗原を標的指向するキメラ抗原受容体 Download PDF

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JP6359520B2
JP6359520B2 JP2015505765A JP2015505765A JP6359520B2 JP 6359520 B2 JP6359520 B2 JP 6359520B2 JP 2015505765 A JP2015505765 A JP 2015505765A JP 2015505765 A JP2015505765 A JP 2015505765A JP 6359520 B2 JP6359520 B2 JP 6359520B2
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ノーブル コッフェンダーファー、ジェームズ
ノーブル コッフェンダーファー、ジェームズ
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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    • C07K2319/00—Fusion polypeptide
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JP2015505765A 2012-04-11 2013-03-15 Ｂ細胞成熟抗原を標的指向するキメラ抗原受容体 Active JP6359520B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261622600P 2012-04-11 2012-04-11
US61/622,600 2012-04-11
PCT/US2013/032029 WO2013154760A1 (en) 2012-04-11 2013-03-15 Chimeric antigen receptors targeting b-cell maturation antigen

Related Child Applications (1)

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JP2018117381A Division JP6657317B2 (ja) 2012-04-11 2018-06-20 Ｂ細胞成熟抗原を標的指向するキメラ抗原受容体

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JP2015513920A JP2015513920A (ja) 2015-05-18
JP2015513920A5 JP2015513920A5 (enExample) 2016-05-12
JP6359520B2 true JP6359520B2 (ja) 2018-07-18

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JP2015505765A Active JP6359520B2 (ja) 2012-04-11 2013-03-15 Ｂ細胞成熟抗原を標的指向するキメラ抗原受容体
JP2018117381A Active JP6657317B2 (ja) 2012-04-11 2018-06-20 Ｂ細胞成熟抗原を標的指向するキメラ抗原受容体
JP2020018005A Active JP6989634B2 (ja) 2012-04-11 2020-02-05 Ｂ細胞成熟抗原を標的指向するキメラ抗原受容体
JP2021196490A Active JP7778549B2 (ja) 2012-04-11 2021-12-02 Ｂ細胞成熟抗原を標的指向するキメラ抗原受容体
JP2023146498A Pending JP2023175763A (ja) 2012-04-11 2023-09-08 Ｂ細胞成熟抗原を標的指向するキメラ抗原受容体

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JP2020018005A Active JP6989634B2 (ja) 2012-04-11 2020-02-05 Ｂ細胞成熟抗原を標的指向するキメラ抗原受容体
JP2021196490A Active JP7778549B2 (ja) 2012-04-11 2021-12-02 Ｂ細胞成熟抗原を標的指向するキメラ抗原受容体
JP2023146498A Pending JP2023175763A (ja) 2012-04-11 2023-09-08 Ｂ細胞成熟抗原を標的指向するキメラ抗原受容体

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US (20) US9765342B2 (enExample)
EP (3) EP3689383A1 (enExample)
JP (5) JP6359520B2 (enExample)
KR (5) KR20210032014A (enExample)
CN (3) CN110331154A (enExample)
AU (5) AU2013246443B2 (enExample)
BR (1) BR112014024893B8 (enExample)
CA (1) CA2869562C (enExample)
EA (2) EA201990959A1 (enExample)
HK (1) HK1203393A1 (enExample)
IL (4) IL234870B (enExample)
IS (1) IS9056A (enExample)
MX (3) MX394639B (enExample)
NZ (1) NZ700362A (enExample)
RU (2) RU2650805C2 (enExample)
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Cited By (4)

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JP2018161140A (ja) * 2012-04-11 2018-10-18 アメリカ合衆国 Ｂ細胞成熟抗原を標的指向するキメラ抗原受容体
US11608382B2 (en) 2018-06-13 2023-03-21 Novartis Ag BCMA chimeric antigen receptors and uses thereof
US12214037B2 (en) 2014-07-21 2025-02-04 Novartis Ag Treatment of cancer using humanized anti-BCMA chimeric antigen receptor
US12383601B2 (en) 2019-11-26 2025-08-12 Novartis Ag Chimeric antigen receptors and uses thereof

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