JP6272757B2 - ２，４−ペンタジエノエート、ブタジエン、プロピレン、１，３−ブタンジオールおよび関連アルコールを生成するための微生物および方法 - Google Patents

２，４−ペンタジエノエート、ブタジエン、プロピレン、１，３−ブタンジオールおよび関連アルコールを生成するための微生物および方法 Download PDF

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JP6272757B2
JP6272757B2 JP2014526243A JP2014526243A JP6272757B2 JP 6272757 B2 JP6272757 B2 JP 6272757B2 JP 2014526243 A JP2014526243 A JP 2014526243A JP 2014526243 A JP2014526243 A JP 2014526243A JP 6272757 B2 JP6272757 B2 JP 6272757B2
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coa
pathway
butanediol
reductase
microbial organism
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JP2014521365A (ja
JP2014521365A5 (enExample
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ロビン イー． オステラウト，
ロビン イー． オステラウト，
アンソニー ピー． バーガード，
アンソニー ピー． バーガード，
マーク ジェイ． バーク，
マーク ジェイ． バーク，
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ジェノマティカ， インコーポレイテッド
ジェノマティカ， インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/16—Butanols
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
    • C12P5/026—Unsaturated compounds, i.e. alkenes, alkynes or allenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
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  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2014526243A 2011-08-19 2012-08-17 ２，４−ペンタジエノエート、ブタジエン、プロピレン、１，３−ブタンジオールおよび関連アルコールを生成するための微生物および方法 Expired - Fee Related JP6272757B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201161525659P 2011-08-19 2011-08-19
US61/525,659 2011-08-19
US201161530885P 2011-09-02 2011-09-02
US61/530,885 2011-09-02
US201161535264P 2011-09-15 2011-09-15
US61/535,264 2011-09-15
US201261645509P 2012-05-10 2012-05-10
US61/645,509 2012-05-10
PCT/US2012/051347 WO2013028519A1 (en) 2011-08-19 2012-08-17 Microorganisms and methods for producing 2,4-pentadienoate, butadiene, propylene, 1,3-butanediol and related alcohols

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JP2014521365A5 JP2014521365A5 (enExample) 2015-10-01
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JP2017192823A Pending JP2017221230A (ja) 2011-08-19 2017-10-02 ２，４−ペンタジエノエート、ブタジエン、プロピレン、１，３−ブタンジオールおよび関連アルコールを生成するための微生物および方法

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US (3) US20130109064A1 (enExample)
EP (2) EP2744906B1 (enExample)
JP (2) JP6272757B2 (enExample)
KR (2) KR20190127993A (enExample)
CN (1) CN103890185A (enExample)
AU (1) AU2012299191B2 (enExample)
BR (1) BR112014003708A2 (enExample)
CA (1) CA2845681A1 (enExample)
CO (1) CO7020858A2 (enExample)
IN (1) IN2014CN01258A (enExample)
MX (1) MX348612B (enExample)
PH (1) PH12014500391A1 (enExample)
SG (2) SG10201600618QA (enExample)
WO (1) WO2013028519A1 (enExample)

Families Citing this family (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102753698A (zh) * 2009-12-10 2012-10-24 基因组股份公司 合成气或其他气态碳源和甲醇转化为1,3-丁二醇的方法和有机体
WO2012018624A2 (en) * 2010-07-26 2012-02-09 Genomatica, Inc. Microorganisms and methods for the biosynthesis of aromatics, 2,4-pentadienoate and 1,3-butadiene
WO2012174439A2 (en) 2011-06-17 2012-12-20 Invista Technologies S.A R.L. Methods of producing four carbon molecules
US9334508B2 (en) 2011-06-17 2016-05-10 Invista North America S.A.R.L. Methods of producing carboxylic acids
US9422578B2 (en) 2011-06-17 2016-08-23 Invista North America S.A.R.L. Methods for biosynthesizing 1,3 butadiene
BR112013033672A2 (pt) 2011-06-30 2017-03-14 Invista Tech Sarl método para converter um composto, cultura substancialmente pura de células hospedeiras e cèlula isolada
US9102960B2 (en) 2011-12-16 2015-08-11 Invista North America S.á.r.l. Methods of producing 6-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage
US9102958B2 (en) 2011-12-16 2015-08-11 Invista North America S.á.r.l. Methods of producing 6-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage
US8703455B2 (en) 2012-08-29 2014-04-22 Scientist of Fourtune, S.A. Production of volatile dienes by enzymatic dehydration of light alkenols
CN104870645A (zh) * 2012-09-24 2015-08-26 昭和电工株式会社 丁二醇的制造方法
WO2014076016A1 (en) * 2012-11-13 2014-05-22 Global Bioenergies Process for the enzymatic preparation of isoprene from isoprenol
EP2925871A1 (en) 2012-11-28 2015-10-07 Invista Technologies S.A R.L. Methods for biosynthesis of isobutene
WO2014093847A2 (en) 2012-12-14 2014-06-19 Invista North America S.A.R.L. METHODS OF PRODUCING 7-CARBON CHEMICALS VIA CoA-DEPENDENT CARBON CHAIN ELONGATION ASSOCIATED WITH CARBON STORAGE
EP2938734A2 (en) 2012-12-31 2015-11-04 Invista Technologies S.A R.L. Methods of producing 7-carbon chemicals via aromatic compounds
WO2014105790A2 (en) 2012-12-31 2014-07-03 Invista North America S.A.R.L. Methods of producing 7-carbon chemicals via c1 carbon chain elongation associated with coenzyme b synthesis
CN105073214A (zh) 2012-12-31 2015-11-18 英威达技术有限责任公司 通过甲酯保护的碳链延伸生产6碳化学物的方法
US10196657B2 (en) 2012-12-31 2019-02-05 Invista North America S.A.R.L. Methods of producing 7-carbon chemicals via methyl-ester shielded carbon chain elongation
WO2014105788A2 (en) 2012-12-31 2014-07-03 Invista North America S.A.R.L. Methods of producing 7-carbon chemicals via carbon chain elongation associated with cyclohexane carboxylate synthesis
US9738911B2 (en) 2012-12-31 2017-08-22 Invista North America S.A.R.L. Methods of producing 7-carbon chemicals via pyruvate and succinate semialdehyde aldol condensation
CN105026570A (zh) 2012-12-31 2015-11-04 英威达技术有限责任公司 通过氧化裂解从长链脂肪酸生产7-碳化学物的方法
WO2014152434A2 (en) 2013-03-15 2014-09-25 Genomatica, Inc. Microorganisms and methods for producing butadiene and related compounds by formate assimilation
CA2908572A1 (en) 2013-05-17 2014-11-20 Global Bioenergies Alkenol dehydratase variants
EP3017051B1 (en) * 2013-07-03 2021-06-30 Scientist of Fortune S.A. Method for the enzymatic production of 3-buten-2-one
US10294496B2 (en) 2013-07-19 2019-05-21 Invista North America S.A.R.L. Methods for biosynthesizing 1,3 butadiene
WO2015021045A2 (en) 2013-08-05 2015-02-12 INVISTA North America S.á r.l. Methods for biosynthesis of isoprene
BR112016002626A2 (pt) 2013-08-05 2017-09-12 Invista Tech Sarl método para sintetizar isobuteno e hospedeiro recombinante
WO2015035226A2 (en) * 2013-09-05 2015-03-12 Braskem S/A Modified microorganism and methods of using same for producing 2- propanol and 1-propanol and/or 1.2-propanediol
PL3077501T3 (pl) 2013-12-03 2022-01-31 Genomatica, Inc. Mikroorganizmy i sposoby poprawy wydajności produktu na metanolu z użyciem syntezy acetylo-coa
BR112016012371B1 (pt) * 2013-12-05 2023-03-28 Genomatica, Inc Célula bacteriana recombinante para a produção de uma amina graxa, cultura de células e método de produção de uma amina graxa
ES2800606T3 (es) 2013-12-27 2021-01-04 Genomatica Inc Métodos y organismos con mayores eficiencias del flujo de carbono
BR112016026461A2 (pt) 2014-05-15 2017-12-12 Invista Tech Sarl métodos de produção de produtos químicos com 6 carbonos com uso de 2,6-diaminopimelato como precursor para 2-aminopimelato
PT3142785T (pt) 2014-05-16 2022-07-29 Versalis Spa Processo para a produção de alcenóis e sua utilização para a produção de 1,3-butadieno
US20150361464A1 (en) * 2014-06-16 2015-12-17 INVISTA North America S.á r.l. Methods, reagents and cells for biosynthesizing compounds
BR112016029391A2 (pt) 2014-06-16 2017-10-17 Invista Tech Sarl métodos, reagentes e células para biossintetizar compostos
US9938543B2 (en) 2014-06-16 2018-04-10 Invista North America S.A.R.L. Methods, reagents and cells for biosynthesizing glutarate methyl ester
WO2015195707A1 (en) 2014-06-16 2015-12-23 Invista Technologies S.A.R.L. Methods, reagents and cells for biosynthesizing compounds
BR112016029388A2 (pt) 2014-06-16 2017-10-17 Invista Tech Sarl métodos, reagentes e células para biossintetizar compostos
US10669561B2 (en) 2014-07-03 2020-06-02 Genomatica, Inc. Microorganisms for producing 4C-5C compounds with unsaturation and methods related thereto
US10487342B2 (en) 2014-07-11 2019-11-26 Genomatica, Inc. Microorganisms and methods for the production of butadiene using acetyl-CoA
BR112017001105A2 (pt) * 2014-07-18 2018-07-24 REG Life Sciences, LLC produção microbiana de dióis graxos
BR112017003733A2 (pt) * 2014-09-03 2017-12-05 Global Bioenergies ?micro-organismo recombinante que produz alcenos a partir de acetil-coa?.
US20170298363A1 (en) 2014-09-18 2017-10-19 Genomatica, Inc Non-natural microbial organisms with improved energetic efficiency
BR112017010010A2 (pt) * 2014-11-14 2018-02-06 Invista Tech Sarl método para produzir 3-oxo-5-hidroxipentanoil-coa, método para biossintetizar 1,3-butanodiol, hospedeiro recombinante, produto bioderivado, produto biobaseado ou produto derivado de fermentação, retícula bioquímica de ocorrência não natural, construto de ácido nucleico ou vetor de expressão e composição
EP3026118A1 (de) * 2014-11-25 2016-06-01 LANXESS Deutschland GmbH Enzymatisches Verfahren zur Herstellung von 3-Butenal und 3-Buten-1-ol
JP6797110B2 (ja) 2014-12-12 2020-12-09 ベルサリス、ソシエタ、ペル、アチオニＶｅｒｓａｌｉｓ Ｓ．Ｐ．Ａ． １，３−ブタジエンの１，３−ブタンジオールからの製造方法
MX2017010570A (es) 2015-02-23 2017-12-07 Versalis Spa Proceso para la deshidratacion de compuestos oxigenados.
BR112017021667A2 (pt) 2015-04-09 2018-07-24 Genomatica Inc microorganismos modificados & métodos para produção aperfeiçoada de álcool de crotila
KR101839595B1 (ko) 2015-04-13 2018-04-26 한국과학기술원 락탐의 제조방법
BR112017025554B1 (pt) 2015-05-30 2024-03-12 Genomatica, Inc. Composição, e, método para produzir um polímero, resina ou artigo de fabricação
KR101651239B1 (ko) * 2015-07-02 2016-08-25 씨제이제일제당 주식회사 신규 슈도모나스 종 균주 및 이를 이용한 6-아미노카프로산의 탈아민 방법
EP3368548B1 (en) 2015-10-30 2023-08-23 Genomatica, Inc. Methanol dehydrogenase fusion proteins
US10570379B2 (en) * 2015-11-13 2020-02-25 Invista North America S.A.R.L. Polypeptides for carbon-carbon bond formation and uses thereof
EP3377639A2 (en) 2015-11-17 2018-09-26 Global Bioenergies Methods for producing isobutene from 3-methylcrotonic acid
GB201605354D0 (en) 2016-03-30 2016-05-11 Zuvasyntha Ltd Modified enzyme
AU2017260270B2 (en) * 2016-05-04 2022-11-17 Global Bioenergies 3-methylcrotonic acid decarboxylase (MDC) variants
ES2835648T3 (es) * 2016-05-09 2021-06-22 Procter & Gamble Composición detergente que comprende una descarboxilasa de ácidos grasos
EP3511403B1 (en) * 2016-05-09 2020-12-02 The Procter & Gamble Company Detergent composition
BR112019000633A2 (pt) 2016-07-12 2019-07-09 Braskem Sa formação de alquenos através de desidratação enzimática de alcanóis
US11332723B2 (en) 2016-10-03 2022-05-17 The Regents Of The University Of California Engineered microorganisms for production of commodity chemicals and cellular biomass
CN107915579B (zh) * 2016-10-09 2020-06-09 中国石油化工股份有限公司 丁二烯合成1,4-丁二醇的方法
IT201600105178A1 (it) 2016-10-19 2018-04-19 Versalis Spa Procedimento per la produzione di dieni
CA3059650C (en) 2017-05-10 2023-12-19 Global Bioenergies Improved methods for producing isobutene from 3-methylcrotonic acid
US11634733B2 (en) 2017-06-30 2023-04-25 Inv Nylon Chemicals Americas, Llc Methods, materials, synthetic hosts and reagents for the biosynthesis of hydrocarbons and derivatives thereof
US11162115B2 (en) 2017-06-30 2021-11-02 Inv Nylon Chemicals Americas, Llc Methods, synthetic hosts and reagents for the biosynthesis of hydrocarbons
US11505809B2 (en) 2017-09-28 2022-11-22 Inv Nylon Chemicals Americas Llc Organisms and biosynthetic processes for hydrocarbon synthesis
US20210079334A1 (en) 2018-01-30 2021-03-18 Genomatica, Inc. Fermentation systems and methods with substantially uniform volumetric uptake rate of a reactive gaseous component
WO2019207812A1 (ja) * 2018-04-27 2019-10-31 株式会社Ｃｏ２資源化研究所 ヒドロゲノフィラス属細菌形質転換体
JP2021528977A (ja) 2018-06-26 2021-10-28 ジェノマティカ， インコーポレイテッド グリセルアルデヒド３−リン酸（ｇ３ｐ）を３−ホスホグリセリン酸（３ｐｇ）に変換する酵素および／またはフルクトース−１，６−ビスホスファターゼを有する組換え微生物（合成または増強されたメチロトロフィーを有するものを含む）
MX2021003364A (es) 2018-09-21 2021-08-16 Versalis Spa Proceso para la purificacion de bio-1,3-butanodiol a partir de un caldo de fermentacion.
JP7370587B2 (ja) * 2018-10-30 2023-10-30 ＧｒｅｅｎＥａｒｔｈＩｎｓｔｉｔｕｔｅ株式会社 有機化合物の製造方法およびコリネ型細菌
CN111315888A (zh) * 2018-10-30 2020-06-19 绿色地球研究所株式会社 有机化合物的制造方法及棒状细菌
IT201900015069A1 (it) 2019-08-27 2021-02-27 Versalis Spa Catalizzatore comprendente coke e procedimento per la produzione di dieni.
KR102212882B1 (ko) * 2019-09-25 2021-02-08 한국원자력연구원 지방산 생산능이 증가된 클라미도모나스 속 미세조류 및 클라미도모나스 속 미세조류의 지방산 생산능을 증가시키는 방법
CN110564662B (zh) * 2019-09-30 2022-03-25 南京农业大学 一种整合型高效表达乙醛脱氢酶枯草杆菌的构建方法
EP4065181A1 (de) * 2019-11-27 2022-10-05 Symrise AG Vorrichtung und verfahren zur analytischen und sensorischen bestimmung der freisetzung eines wirkstoffs aus einem freisetzungssystem
IT201900025000A1 (it) 2019-12-20 2021-06-20 Versalis Spa Procedimento per la produzione di dieni.
CN111269848B (zh) * 2019-12-30 2022-03-18 浙江工业大学 赤红球菌jj-3及其在降解丙烯酸中的应用
JP7475598B2 (ja) * 2020-03-04 2024-04-30 大阪瓦斯株式会社 １，３－ブタンジオールの製造方法
EP4269593A4 (en) * 2020-12-28 2025-08-13 Riken PROCESS FOR PRODUCING AN UNSATURATED CHAIN CARBOXYLIC ACID COMPOUND USING PHENYLALANINE AMMONIA LYASE
CN112625921B (zh) * 2020-12-29 2022-05-20 中国科学院成都生物研究所 一种用于处理高木质素含量废弃物的菌制剂
BR112023009059A2 (pt) * 2021-03-08 2023-10-03 Lanzatech Inc Micro-organismo geneticamente manipulado capaz de produzir um produto a partir de um substrato gasoso
CN113122563B (zh) * 2021-04-22 2023-12-08 洛阳华荣生物技术有限公司 构建r-3-氨基丁酸生产菌的方法
CN114717208B (zh) * 2022-05-18 2024-07-09 上海交通大学 一种酰基CoA合成酶及其应用
CN114990043B (zh) * 2022-06-28 2024-04-30 滨州医学院 代谢赖氨酸的工程菌及其构建方法与应用
CN115845899B (zh) * 2022-12-02 2024-03-01 平顶山学院 一种催化1，3-丁二烯双羰基化合成己二酸甲酯的催化剂的制备方法
WO2025032068A1 (en) * 2023-08-07 2025-02-13 Photanol B.V. Propylene production in cyanobacteria
CN117701489B (zh) * 2024-02-05 2024-05-10 北京绿色康成生物技术有限公司 一种提高大肠杆菌生产1,3-丁二醇的方法
CN117887641B (zh) * 2024-03-13 2024-05-14 南京农业大学 一株兼具苯胺降解及聚羟基丁酸酯合成能力的菌株及其应用

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3090815A (en) 1963-05-21 Isomerization of alkylene oxide
US3090816A (en) 1963-05-21 Isomerization of alkylene oxide
US3542883A (en) 1966-08-10 1970-11-24 Costin Nenitescu Process for isomerization of 1,2-alkylene oxides
US4400562A (en) 1981-07-02 1983-08-23 The United States Of America As Represented By The Secretary Of The Navy Alkenol synthesis
US5958745A (en) 1996-03-13 1999-09-28 Monsanto Company Methods of optimizing substrate pools and biosynthesis of poly-β-hydroxybutyrate-co-poly-β-hydroxyvalerate in bacteria and plants
US6262262B1 (en) 1997-09-26 2001-07-17 Eli Lilly And Company Processes and intermediates useful to make antifolates
AU3482200A (en) 1999-02-02 2000-08-25 Bernhard Palsson Methods for identifying drug targets based on genomic sequence data
US7186541B2 (en) 2000-11-20 2007-03-06 Cargill, Incorporated 3-hydroxypropionic acid and other organic compounds
JP4776146B2 (ja) 2001-01-10 2011-09-21 ザ・ペン・ステート・リサーチ・ファンデーション 細胞代謝をモデル化する方法及びシステム
US7127379B2 (en) 2001-01-31 2006-10-24 The Regents Of The University Of California Method for the evolutionary design of biochemical reaction networks
CA2439260C (en) 2001-03-01 2012-10-23 The Regents Of The University Of California Models and methods for determining systemic properties of regulated reaction networks
US20030224363A1 (en) 2002-03-19 2003-12-04 Park Sung M. Compositions and methods for modeling bacillus subtilis metabolism
CA2480216A1 (en) 2002-03-29 2003-10-09 Genomatica, Inc. Human metabolic models and methods
US7856317B2 (en) 2002-06-14 2010-12-21 Genomatica, Inc. Systems and methods for constructing genomic-based phenotypic models
JP4418793B2 (ja) 2002-07-10 2010-02-24 ザ ペン ステート リサーチ ファウンデーション 遺伝子ノックアウト戦略を決定する方法
ATE505559T1 (de) 2002-09-12 2011-04-15 Metabolix Inc Produktion von polyhydroxyalkanoat mittels coenzym-a-abhängiger aldehyd-dehydrogenase-wege
CA2500761C (en) 2002-10-15 2012-11-20 Bernhard O. Palsson Methods and systems to identify operational reaction pathways
CN1246465C (zh) * 2004-04-29 2006-03-22 清华大学 微生物两段发酵法由甘油生产1，3－丙二醇和2，3－丁二醇
DE102006025821A1 (de) 2006-06-02 2007-12-06 Degussa Gmbh Ein Enzym zur Herstellung von Mehylmalonatsemialdehyd oder Malonatsemialdehyd
US20080293086A1 (en) * 2006-09-18 2008-11-27 Cobalt Technologies, Inc. A Delaware Corporation Real time monitoring of microbial enzymatic pathways
EP2017344A1 (en) 2007-07-20 2009-01-21 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Production of itaconic acid
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
EP2285948B1 (en) * 2008-03-03 2014-01-08 Joule Unlimited Technologies, Inc. Engineered co2 fixing microorganisms producing carbon-based products of interest
WO2009155382A1 (en) * 2008-06-17 2009-12-23 Genomatica, Inc. Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate
CN102317437B (zh) 2008-12-12 2013-08-21 麦特波力克斯公司 用于制备聚(5-羟基戊酸)和5碳化合物的绿色工艺和组合物
EP3865569B1 (en) * 2009-04-30 2023-10-04 Genomatica, Inc. Organisms for the production of 1,3-butanediol
JP4760951B2 (ja) * 2009-05-08 2011-08-31 トヨタ自動車株式会社 ブタノール生産能を有する組換え微生物及びブタノールの製造方法
EP2467490A1 (en) 2009-08-21 2012-06-27 Mascoma Corporation Production of propanols, alcohols, and polyols in consolidated bioprocessing organisms
US8715971B2 (en) 2009-09-09 2014-05-06 Genomatica, Inc. Microorganisms and methods for the co-production of isopropanol and 1,4-butanediol
US20120276606A1 (en) * 2009-10-30 2012-11-01 Daicel Corporation Recombinant microorganisms with 1,3-butanediol-producing function and uses thereof
CN102753698A (zh) * 2009-12-10 2012-10-24 基因组股份公司 合成气或其他气态碳源和甲醇转化为1,3-丁二醇的方法和有机体
US8048661B2 (en) * 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
KR20190006103A (ko) * 2010-05-05 2019-01-16 게노마티카 인코포레이티드 부타디엔을 생합성하기 위한 미생물 및 방법

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