AU2012299191B2 - Microorganisms and methods for producing 1,3-butanediol and related alcohols - Google Patents

Microorganisms and methods for producing 1,3-butanediol and related alcohols Download PDF

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Publication number
AU2012299191B2
AU2012299191B2 AU2012299191A AU2012299191A AU2012299191B2 AU 2012299191 B2 AU2012299191 B2 AU 2012299191B2 AU 2012299191 A AU2012299191 A AU 2012299191A AU 2012299191 A AU2012299191 A AU 2012299191A AU 2012299191 B2 AU2012299191 B2 AU 2012299191B2
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Prior art keywords
coa
butanediol
pathway
butadiene
reductase
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Ceased
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AU2012299191A
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AU2012299191A1 (en
Inventor
Anthony P. Burgard
Mark J. Burk
Robin E. Osterhout
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Genomatica Inc
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Genomatica Inc
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Priority to AU2013202925A priority Critical patent/AU2013202925B2/en
Priority to AU2013202930A priority patent/AU2013202930B2/en
Publication of AU2012299191A1 publication Critical patent/AU2012299191A1/en
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Publication of AU2012299191B2 publication Critical patent/AU2012299191B2/en
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/16—Butanols
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
    • C12P5/026—Unsaturated compounds, i.e. alkenes, alkynes or allenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2012299191A 2011-08-19 2012-08-17 Microorganisms and methods for producing 1,3-butanediol and related alcohols Ceased AU2012299191B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2013202925A AU2013202925B2 (en) 2011-08-19 2013-04-08 Microorganisms and methods for producing 1,3-butanediol and related alcohols
AU2013202930A AU2013202930B2 (en) 2011-08-19 2013-04-08 Microorganisms and methods for producing 1,3-butanediol and related alcohols

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201161525659P 2011-08-19 2011-08-19
US61/525,659 2011-08-19
US201161530885P 2011-09-02 2011-09-02
US61/530,885 2011-09-02
US201161535264P 2011-09-15 2011-09-15
US61/535,264 2011-09-15
US201261645509P 2012-05-10 2012-05-10
US61/645,509 2012-05-10
PCT/US2012/051347 WO2013028519A1 (en) 2011-08-19 2012-08-17 Microorganisms and methods for producing 2,4-pentadienoate, butadiene, propylene, 1,3-butanediol and related alcohols

Related Child Applications (2)

Application Number Title Priority Date Filing Date
AU2013202930A Division AU2013202930B2 (en) 2011-08-19 2013-04-08 Microorganisms and methods for producing 1,3-butanediol and related alcohols
AU2013202925A Division AU2013202925B2 (en) 2011-08-19 2013-04-08 Microorganisms and methods for producing 1,3-butanediol and related alcohols

Publications (2)

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AU2012299191A1 AU2012299191A1 (en) 2013-05-02
AU2012299191B2 true AU2012299191B2 (en) 2016-03-03

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AU2012299191A Ceased AU2012299191B2 (en) 2011-08-19 2012-08-17 Microorganisms and methods for producing 1,3-butanediol and related alcohols

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US (3) US20130109064A1 (enExample)
EP (2) EP2744906B1 (enExample)
JP (2) JP6272757B2 (enExample)
KR (2) KR20190127993A (enExample)
CN (1) CN103890185A (enExample)
AU (1) AU2012299191B2 (enExample)
BR (1) BR112014003708A2 (enExample)
CA (1) CA2845681A1 (enExample)
CO (1) CO7020858A2 (enExample)
IN (1) IN2014CN01258A (enExample)
MX (1) MX348612B (enExample)
PH (1) PH12014500391A1 (enExample)
SG (2) SG10201600618QA (enExample)
WO (1) WO2013028519A1 (enExample)

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