JP6156144B2 - 親和性複合体に対する抗体 - Google Patents

親和性複合体に対する抗体 Download PDF

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Publication number
JP6156144B2
JP6156144B2 JP2013534624A JP2013534624A JP6156144B2 JP 6156144 B2 JP6156144 B2 JP 6156144B2 JP 2013534624 A JP2013534624 A JP 2013534624A JP 2013534624 A JP2013534624 A JP 2013534624A JP 6156144 B2 JP6156144 B2 JP 6156144B2
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Prior art keywords
antibody
vitamin
affinity complex
complex
affinity
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Japanese (ja)
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JPWO2013042426A1 (ja
Inventor
和也 小見
和也 小見
豪 安藤
豪 安藤
内田　好昭
好昭 内田
勝利 碁石
勝利 碁石
麻子 岡
麻子 岡
貴志 白川
貴志 白川
拓弥 佐久
拓弥 佐久
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Fujirebio Inc
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Fujirebio Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/743—Steroid hormones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/32—Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Endocrinology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2013534624A 2011-09-21 2012-07-04 親和性複合体に対する抗体 Active JP6156144B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2011206162 2011-09-21
JP2011206162 2011-09-21
JP2012006359 2012-01-16
JP2012006359 2012-01-16
PCT/JP2012/067062 WO2013042426A1 (ja) 2011-09-21 2012-07-04 親和性複合体に対する抗体

Publications (2)

Publication Number Publication Date
JPWO2013042426A1 JPWO2013042426A1 (ja) 2015-03-26
JP6156144B2 true JP6156144B2 (ja) 2017-07-05

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JP2013534624A Active JP6156144B2 (ja) 2011-09-21 2012-07-04 親和性複合体に対する抗体

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US (1) US9599608B2 (enExample)
EP (1) EP2759551B1 (enExample)
JP (1) JP6156144B2 (enExample)
KR (1) KR101720394B1 (enExample)
CN (1) CN103827145A (enExample)
AU (1) AU2012310880B2 (enExample)
BR (1) BR112014006405A2 (enExample)
CA (1) CA2849274C (enExample)
IL (1) IL231404A0 (enExample)
IN (1) IN2014CN02113A (enExample)
RU (1) RU2014115676A (enExample)
TW (1) TW201313743A (enExample)
WO (1) WO2013042426A1 (enExample)

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EP2759550B1 (en) 2013-01-28 2018-08-15 DiaSorin S.p.A. Method and kit for detecting 1,25-dihydroxyvitamin D and related antibodies
KR101840525B1 (ko) 2013-02-06 2018-03-20 후지레비오 가부시키가이샤 비타민 d 의 측정 방법 및 측정용 키트
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CN106244562B (zh) * 2016-05-20 2019-07-23 杭州奥泰生物技术股份有限公司 杂交瘤细胞株及其分泌的抗25羟基维生素d3单克隆抗体和应用
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Also Published As

Publication number Publication date
RU2014115676A (ru) 2015-10-27
EP2759551B1 (en) 2019-05-22
IL231404A0 (en) 2014-04-30
US20150037813A1 (en) 2015-02-05
KR20140044940A (ko) 2014-04-15
KR101720394B1 (ko) 2017-03-27
BR112014006405A2 (pt) 2017-04-04
JPWO2013042426A1 (ja) 2015-03-26
EP2759551A4 (en) 2015-03-04
AU2012310880A1 (en) 2014-04-10
CN103827145A (zh) 2014-05-28
CA2849274C (en) 2018-12-04
TW201313743A (zh) 2013-04-01
WO2013042426A1 (ja) 2013-03-28
EP2759551A1 (en) 2014-07-30
US9599608B2 (en) 2017-03-21
IN2014CN02113A (enExample) 2015-05-29
AU2012310880B2 (en) 2015-12-03
CA2849274A1 (en) 2013-03-28

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