KR101720394B1 - 친화성 복합체에 대한 항체 - Google Patents

친화성 복합체에 대한 항체 Download PDF

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Publication number
KR101720394B1
KR101720394B1 KR1020147006583A KR20147006583A KR101720394B1 KR 101720394 B1 KR101720394 B1 KR 101720394B1 KR 1020147006583 A KR1020147006583 A KR 1020147006583A KR 20147006583 A KR20147006583 A KR 20147006583A KR 101720394 B1 KR101720394 B1 KR 101720394B1
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South Korea
Prior art keywords
antibody
vitamin
affinity complex
complex
affinity
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Expired - Fee Related
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English (en)
Korean (ko)
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KR20140044940A (ko
Inventor
가즈야 오미
츠요시 안도
요시아키 우치다
가츠토시 고이시
아사코 오카
다카시 시라카와
다쿠야 사큐
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후지레비오 가부시키가이샤
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/743—Steroid hormones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/32—Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1020147006583A 2011-09-21 2012-07-04 친화성 복합체에 대한 항체 Expired - Fee Related KR101720394B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JPJP-P-2011-206162 2011-09-21
JP2011206162 2011-09-21
JPJP-P-2012-006359 2012-01-16
JP2012006359 2012-01-16
PCT/JP2012/067062 WO2013042426A1 (ja) 2011-09-21 2012-07-04 親和性複合体に対する抗体

Publications (2)

Publication Number Publication Date
KR20140044940A KR20140044940A (ko) 2014-04-15
KR101720394B1 true KR101720394B1 (ko) 2017-03-27

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US (1) US9599608B2 (enExample)
EP (1) EP2759551B1 (enExample)
JP (1) JP6156144B2 (enExample)
KR (1) KR101720394B1 (enExample)
CN (1) CN103827145A (enExample)
AU (1) AU2012310880B2 (enExample)
BR (1) BR112014006405A2 (enExample)
CA (1) CA2849274C (enExample)
IL (1) IL231404A0 (enExample)
IN (1) IN2014CN02113A (enExample)
RU (1) RU2014115676A (enExample)
TW (1) TW201313743A (enExample)
WO (1) WO2013042426A1 (enExample)

Families Citing this family (15)

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US11261257B2 (en) 2013-01-28 2022-03-01 Diasorin S.P.A. Methods for detecting 1,25-dihydroxyvitamin D and related antibodies
US10983136B2 (en) 2013-01-28 2021-04-20 Diasorin S.P.A. Use of 1,25-dihydroxyvitamin D values in ratio with PTH as a prognostic biomarker
DK2759550T3 (en) 2013-01-28 2018-11-26 Diasorin S P A Method and kit for detecting vitamin 1,25-dihydroxy-D and related antibodies
KR101840525B1 (ko) 2013-02-06 2018-03-20 후지레비오 가부시키가이샤 비타민 d 의 측정 방법 및 측정용 키트
WO2015129651A1 (ja) * 2014-02-25 2015-09-03 富士レビオ株式会社 改変単量体ＩｇＭ
CN108779169B (zh) 2015-12-21 2022-06-07 图尔库大学 针对包含蓝细菌环肽肝毒素的免疫复合物的抗体
EP3405198B1 (en) 2016-01-22 2021-08-04 Affimedix, Inc. Device for detection of vitamin d metabolites
CN106244562B (zh) * 2016-05-20 2019-07-23 杭州奥泰生物技术股份有限公司 杂交瘤细胞株及其分泌的抗25羟基维生素d3单克隆抗体和应用
JP7177767B2 (ja) * 2016-07-29 2022-11-24 ダイアザイム ラボラトリーズ， インコーポレイテッド ビタミンｄをアッセイするための方法および組成物
AU2018270515A1 (en) 2017-05-19 2019-12-05 The Regents Of The University Of California Antibody chemically induced dimerizer (abCID) as molecular switches for regulating cellular therapies
WO2019131380A1 (ja) 2017-12-25 2019-07-04 富士レビオ株式会社 マクロライド系免疫抑制剤についての血液検査方法
JP7434824B2 (ja) * 2019-11-20 2024-02-21 東ソー株式会社 抗イムノコンプレックス抗体を用いた測定方法
EP4063514A4 (en) * 2019-11-20 2023-11-01 Tosoh Corporation MEASURING METHOD USING ANTI-IMMUNOCOMPLEX ANTIBODIES
JP7683188B2 (ja) * 2019-11-29 2025-05-27 東ソー株式会社 抗イムノコンプレックス抗体を用いた測定法
CN113125696B (zh) * 2019-12-31 2024-03-26 科美博阳诊断技术(上海)有限公司 一种雌二醇均相化学发光检测试剂盒及其应用

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AU2012310880B2 (en) 2015-12-03
EP2759551A4 (en) 2015-03-04
US9599608B2 (en) 2017-03-21
TW201313743A (zh) 2013-04-01
RU2014115676A (ru) 2015-10-27
IN2014CN02113A (enExample) 2015-05-29
KR20140044940A (ko) 2014-04-15
IL231404A0 (en) 2014-04-30
BR112014006405A2 (pt) 2017-04-04
EP2759551A1 (en) 2014-07-30
CN103827145A (zh) 2014-05-28
JPWO2013042426A1 (ja) 2015-03-26
JP6156144B2 (ja) 2017-07-05
US20150037813A1 (en) 2015-02-05
AU2012310880A1 (en) 2014-04-10
CA2849274C (en) 2018-12-04
CA2849274A1 (en) 2013-03-28
EP2759551B1 (en) 2019-05-22
WO2013042426A1 (ja) 2013-03-28

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