CA2849274C - Antibody against affinity complex - Google Patents
Antibody against affinity complex Download PDFInfo
- Publication number
- CA2849274C CA2849274C CA2849274A CA2849274A CA2849274C CA 2849274 C CA2849274 C CA 2849274C CA 2849274 A CA2849274 A CA 2849274A CA 2849274 A CA2849274 A CA 2849274A CA 2849274 C CA2849274 C CA 2849274C
- Authority
- CA
- Canada
- Prior art keywords
- antibody
- affinity complex
- complex
- vitamin
- affinity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/743—Steroid hormones
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/32—Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011-206162 | 2011-09-21 | ||
| JP2011206162 | 2011-09-21 | ||
| JP2012006359 | 2012-01-16 | ||
| JP2012-006359 | 2012-01-16 | ||
| PCT/JP2012/067062 WO2013042426A1 (ja) | 2011-09-21 | 2012-07-04 | 親和性複合体に対する抗体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2849274A1 CA2849274A1 (en) | 2013-03-28 |
| CA2849274C true CA2849274C (en) | 2018-12-04 |
Family
ID=47914207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2849274A Active CA2849274C (en) | 2011-09-21 | 2012-07-04 | Antibody against affinity complex |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9599608B2 (enExample) |
| EP (1) | EP2759551B1 (enExample) |
| JP (1) | JP6156144B2 (enExample) |
| KR (1) | KR101720394B1 (enExample) |
| CN (1) | CN103827145A (enExample) |
| AU (1) | AU2012310880B2 (enExample) |
| BR (1) | BR112014006405A2 (enExample) |
| CA (1) | CA2849274C (enExample) |
| IL (1) | IL231404A0 (enExample) |
| IN (1) | IN2014CN02113A (enExample) |
| RU (1) | RU2014115676A (enExample) |
| TW (1) | TW201313743A (enExample) |
| WO (1) | WO2013042426A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11261257B2 (en) | 2013-01-28 | 2022-03-01 | Diasorin S.P.A. | Methods for detecting 1,25-dihydroxyvitamin D and related antibodies |
| US10983136B2 (en) | 2013-01-28 | 2021-04-20 | Diasorin S.P.A. | Use of 1,25-dihydroxyvitamin D values in ratio with PTH as a prognostic biomarker |
| DK2759550T3 (en) | 2013-01-28 | 2018-11-26 | Diasorin S P A | Method and kit for detecting vitamin 1,25-dihydroxy-D and related antibodies |
| KR101840525B1 (ko) | 2013-02-06 | 2018-03-20 | 후지레비오 가부시키가이샤 | 비타민 d 의 측정 방법 및 측정용 키트 |
| WO2015129651A1 (ja) * | 2014-02-25 | 2015-09-03 | 富士レビオ株式会社 | 改変単量体ＩｇＭ |
| CN108779169B (zh) | 2015-12-21 | 2022-06-07 | 图尔库大学 | 针对包含蓝细菌环肽肝毒素的免疫复合物的抗体 |
| EP3405198B1 (en) | 2016-01-22 | 2021-08-04 | Affimedix, Inc. | Device for detection of vitamin d metabolites |
| CN106244562B (zh) * | 2016-05-20 | 2019-07-23 | 杭州奥泰生物技术股份有限公司 | 杂交瘤细胞株及其分泌的抗25羟基维生素d3单克隆抗体和应用 |
| JP7177767B2 (ja) * | 2016-07-29 | 2022-11-24 | ダイアザイム ラボラトリーズ， インコーポレイテッド | ビタミンｄをアッセイするための方法および組成物 |
| AU2018270515A1 (en) | 2017-05-19 | 2019-12-05 | The Regents Of The University Of California | Antibody chemically induced dimerizer (abCID) as molecular switches for regulating cellular therapies |
| WO2019131380A1 (ja) | 2017-12-25 | 2019-07-04 | 富士レビオ株式会社 | マクロライド系免疫抑制剤についての血液検査方法 |
| JP7434824B2 (ja) * | 2019-11-20 | 2024-02-21 | 東ソー株式会社 | 抗イムノコンプレックス抗体を用いた測定方法 |
| EP4063514A4 (en) * | 2019-11-20 | 2023-11-01 | Tosoh Corporation | MEASURING METHOD USING ANTI-IMMUNOCOMPLEX ANTIBODIES |
| JP7683188B2 (ja) * | 2019-11-29 | 2025-05-27 | 東ソー株式会社 | 抗イムノコンプレックス抗体を用いた測定法 |
| CN113125696B (zh) * | 2019-12-31 | 2024-03-26 | 科美博阳诊断技术(上海)有限公司 | 一种雌二醇均相化学发光检测试剂盒及其应用 |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0091760B1 (en) * | 1982-04-09 | 1986-07-02 | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. | Anti immune complex antibody and preparation thereof |
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| GB8408193D0 (en) * | 1984-03-30 | 1984-05-10 | Cambridge Patent Dev | Antibodies |
| US5807715A (en) * | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US5223441A (en) * | 1986-10-09 | 1993-06-29 | Syntex (U.S.A.) Inc. | Receptors for immune complexes |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5413923A (en) | 1989-07-25 | 1995-05-09 | Cell Genesys, Inc. | Homologous recombination for universal donor cells and chimeric mammalian hosts |
| GB8928874D0 (en) | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
| US5187065A (en) * | 1989-12-22 | 1993-02-16 | Schutzer Steven E | Method and materials for detecting lyme disease |
| DE69133566T2 (de) | 1990-01-12 | 2007-12-06 | Amgen Fremont Inc. | Bildung von xenogenen Antikörpern |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| KR100272077B1 (ko) | 1990-08-29 | 2000-11-15 | 젠팜인터내셔날,인코포레이티드 | 이종 항체를 생산할 수 있는 전이유전자를 가진 인간이외의 동물 |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5814318A (en) | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
| DE69233482T2 (de) | 1991-05-17 | 2006-01-12 | Merck & Co., Inc. | Verfahren zur Verminderung der Immunogenität der variablen Antikörperdomänen |
| US5565332A (en) | 1991-09-23 | 1996-10-15 | Medical Research Council | Production of chimeric antibodies - a combinatorial approach |
| ATE408012T1 (de) | 1991-12-02 | 2008-09-15 | Medical Res Council | Herstellung von autoantikörpern auf phagenoberflächen ausgehend von antikörpersegmentbibliotheken |
| ATE182651T1 (de) | 1992-06-09 | 1999-08-15 | Hoppe Ag | Riegel und türschloss |
| US5639641A (en) | 1992-09-09 | 1997-06-17 | Immunogen Inc. | Resurfacing of rodent antibodies |
| JP4312259B2 (ja) | 1995-04-27 | 2009-08-12 | アムジェン フレモント インク． | 免疫したゼノマウス（ＸｅｎｏＭｏｕｓｅ）に由来するヒト抗体 |
| EP0823941A4 (en) | 1995-04-28 | 2001-09-19 | Abgenix Inc | HUMAN ANTIBODIES DERIVED FROM IMMUNIZED XENO MOUSES |
| US5916771A (en) | 1996-10-11 | 1999-06-29 | Abgenix, Inc. | Production of a multimeric protein by cell fusion method |
| DE69738539T2 (de) | 1996-12-03 | 2009-03-26 | Amgen Fremont Inc. | Vollkommen humane Antikörper die EGFR binden |
| DE69835145T2 (de) | 1997-02-28 | 2007-06-14 | Kirin Beer K.K. | Transgene Mäuse die ein menschliches Antikörper exprimieren |
| TWI255853B (en) | 1998-08-21 | 2006-06-01 | Kirin Brewery | Method for modifying chromosomes |
| US7122339B2 (en) | 1998-10-09 | 2006-10-17 | Medical Research Council | Method for generating diversity |
| CA2375441A1 (en) | 1999-06-04 | 2000-12-14 | Tranxenogen, Inc. | Methods for manipulating the avian genome |
| JP4228095B2 (ja) * | 1999-12-17 | 2009-02-25 | 東ソー株式会社 | 免疫測定方法および免疫測定試薬 |
| JP2001231403A (ja) | 2000-02-18 | 2001-08-28 | Kirin Brewery Co Ltd | 改変された外来染色体あるいはその断片を保持する非ヒト動物 |
| WO2002070648A2 (en) | 2000-11-17 | 2002-09-12 | Hematech, Llc | Expression of xenogenous (human) immunoglobulins in cloned, transgenic ungulates |
| US7435871B2 (en) | 2001-11-30 | 2008-10-14 | Amgen Fremont Inc. | Transgenic animals bearing human Igλ light chain genes |
| CN1930288B (zh) | 2002-04-09 | 2012-08-08 | 协和发酵麒麟株式会社 | 基因组被修饰的细胞 |
| CN100379862C (zh) | 2002-07-30 | 2008-04-09 | 独立行政法人理化学研究所 | 增强体细胞同源重组的方法和构建特异抗体的方法 |
| FI20022048A0 (fi) * | 2002-11-18 | 2002-11-18 | Valtion Teknillinen | Ei-kompetetiivinen immunomääritys pienille analyyteille |
| JP5319863B2 (ja) | 2002-12-26 | 2013-10-16 | 独立行政法人理化学研究所 | 体細胞相同組換えの誘発方法 |
| CA2563064A1 (en) | 2004-04-22 | 2005-11-10 | Kirin Beer Kabushiki Kaisha | Transgenic animals and uses thereof |
| JP2008517600A (ja) | 2004-10-22 | 2008-05-29 | セラピューティック ヒューマン ポリクローナルズ， インコーポレイテッド | ヒト以外のトランスジェニック動物における内因性免疫グロブリン発現の抑制 |
| JP4892717B2 (ja) | 2005-03-31 | 2012-03-07 | 国立大学法人広島大学 | ニワトリキメラ抗体およびその利用 |
| CA2624124A1 (en) * | 2005-09-29 | 2007-04-12 | F. Hoffmann-La Roche Ag | Antibodies against 25-hydroxyvitamin d |
| FI20075251A0 (fi) | 2007-04-13 | 2007-04-13 | Hytest Oy | Immunomääritys epästabiilien antigeenien määrittämiseksi |
| JP2009082033A (ja) | 2007-09-28 | 2009-04-23 | Kaneka Corp | 完全ヒト型抗体生産法 |
| FI20085579A0 (fi) * | 2008-06-12 | 2008-06-12 | Valtion Teknillinen | Kannabiskäytön toteaminen |
| US20110097733A1 (en) * | 2009-10-27 | 2011-04-28 | Michel Anciaux | Process for the production of a hybridoma and antibody obtained therefrom, able to recognize more than one vitamin d metabolite |
-
2012
- 2012-07-04 IN IN2113CHN2014 patent/IN2014CN02113A/en unknown
- 2012-07-04 CN CN201280045570.1A patent/CN103827145A/zh active Pending
- 2012-07-04 AU AU2012310880A patent/AU2012310880B2/en not_active Ceased
- 2012-07-04 BR BR112014006405A patent/BR112014006405A2/pt not_active IP Right Cessation
- 2012-07-04 EP EP12833103.0A patent/EP2759551B1/en active Active
- 2012-07-04 RU RU2014115676/10A patent/RU2014115676A/ru not_active Application Discontinuation
- 2012-07-04 WO PCT/JP2012/067062 patent/WO2013042426A1/ja not_active Ceased
- 2012-07-04 KR KR1020147006583A patent/KR101720394B1/ko not_active Expired - Fee Related
- 2012-07-04 CA CA2849274A patent/CA2849274C/en active Active
- 2012-07-04 JP JP2013534624A patent/JP6156144B2/ja active Active
- 2012-07-04 US US14/346,615 patent/US9599608B2/en active Active
- 2012-07-11 TW TW101124860A patent/TW201313743A/zh unknown
-
2014
- 2014-03-06 IL IL231404A patent/IL231404A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2012310880B2 (en) | 2015-12-03 |
| EP2759551A4 (en) | 2015-03-04 |
| US9599608B2 (en) | 2017-03-21 |
| KR101720394B1 (ko) | 2017-03-27 |
| TW201313743A (zh) | 2013-04-01 |
| RU2014115676A (ru) | 2015-10-27 |
| IN2014CN02113A (enExample) | 2015-05-29 |
| KR20140044940A (ko) | 2014-04-15 |
| IL231404A0 (en) | 2014-04-30 |
| BR112014006405A2 (pt) | 2017-04-04 |
| EP2759551A1 (en) | 2014-07-30 |
| CN103827145A (zh) | 2014-05-28 |
| JPWO2013042426A1 (ja) | 2015-03-26 |
| JP6156144B2 (ja) | 2017-07-05 |
| US20150037813A1 (en) | 2015-02-05 |
| AU2012310880A1 (en) | 2014-04-10 |
| CA2849274A1 (en) | 2013-03-28 |
| EP2759551B1 (en) | 2019-05-22 |
| WO2013042426A1 (ja) | 2013-03-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20140319 |