JP5968879B2 - Ｄｎａ分子タグ技術及びｄｎａ不完全断片化技術に基づいたｐｃｒシークエンシング法及びそれを用いたｈｌａ遺伝子タイピング法 - Google Patents
Ｄｎａ分子タグ技術及びｄｎａ不完全断片化技術に基づいたｐｃｒシークエンシング法及びそれを用いたｈｌａ遺伝子タイピング法 Download PDFInfo
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- JP5968879B2 JP5968879B2 JP2013516983A JP2013516983A JP5968879B2 JP 5968879 B2 JP5968879 B2 JP 5968879B2 JP 2013516983 A JP2013516983 A JP 2013516983A JP 2013516983 A JP2013516983 A JP 2013516983A JP 5968879 B2 JP5968879 B2 JP 5968879B2
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
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- Chemical & Material Sciences (AREA)
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- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
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- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
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- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010213721.2 | 2010-06-30 | ||
| CN201010213717.6 | 2010-06-30 | ||
| CN 201010213721 CN101921842B (zh) | 2010-06-30 | 2010-06-30 | Hla-a,b基因分型用pcr引物及其使用方法 |
| CN201010213719.5 | 2010-06-30 | ||
| CN201010213717.6A CN101921840B (zh) | 2010-06-30 | 2010-06-30 | 一种基于dna分子标签技术和dna不完全打断策略的pcr测序方法 |
| CN201010213719.5A CN101921841B (zh) | 2010-06-30 | 2010-06-30 | 基于Illumina GA测序技术的HLA基因高分辨率分型方法 |
| CNPCT/CN2010/002149 | 2010-12-24 | ||
| PCT/CN2010/002149 WO2012083505A1 (zh) | 2010-12-24 | 2010-12-24 | Hla-c基因分型的方法及其相关引物 |
| CNPCT/CN2010/002150 | 2010-12-24 | ||
| PCT/CN2010/002150 WO2012083506A1 (zh) | 2010-12-24 | 2010-12-24 | Hla-dqb1基因分型的方法及其相关引物 |
| PCT/CN2011/076688 WO2012000445A1 (zh) | 2010-06-30 | 2011-06-30 | 新的的pcr测序方法及其在hla基因分型中的应用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013529472A JP2013529472A (ja) | 2013-07-22 |
| JP2013529472A5 JP2013529472A5 (enExample) | 2014-08-14 |
| JP5968879B2 true JP5968879B2 (ja) | 2016-08-10 |
Family
ID=45401405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013516983A Active JP5968879B2 (ja) | 2010-06-30 | 2011-06-30 | Ｄｎａ分子タグ技術及びｄｎａ不完全断片化技術に基づいたｐｃｒシークエンシング法及びそれを用いたｈｌａ遺伝子タイピング法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9957564B2 (enExample) |
| EP (1) | EP2599877B1 (enExample) |
| JP (1) | JP5968879B2 (enExample) |
| KR (1) | KR101709826B1 (enExample) |
| AU (1) | AU2011274090B2 (enExample) |
| BR (1) | BR112012032586B1 (enExample) |
| CA (1) | CA2803940C (enExample) |
| DK (1) | DK2599877T3 (enExample) |
| MY (1) | MY173793A (enExample) |
| RU (1) | RU2587606C2 (enExample) |
| SG (1) | SG186876A1 (enExample) |
| WO (1) | WO2012000445A1 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201708498VA (en) * | 2013-04-17 | 2017-11-29 | Agency Science Tech & Res | Method for generating extended sequence reads |
| JP6308724B2 (ja) | 2013-05-09 | 2018-04-11 | ジェノダイブファーマ株式会社 | Ｈｌａ遺伝子のマルチプレックスｄｎａタイピング方法及びキット |
| WO2015031385A1 (en) * | 2013-08-26 | 2015-03-05 | The Translational Genomics Research Institute | Single molecule-overlapping read analysis for minor variant mutation detection in pathogen samples |
| GB201409282D0 (en) | 2014-05-23 | 2014-07-09 | Univ Sydney Tech | Sequencing process |
| JP2017525369A (ja) * | 2014-09-05 | 2017-09-07 | キアゲン ゲーエムベーハー | アダプター連結アンプリコンの調製 |
| CN105400864B (zh) * | 2014-09-12 | 2020-04-14 | 深圳华大基因股份有限公司 | 用于基于血液样品构建测序文库的方法及其在确定胎儿遗传异常中的用途 |
| EP3192869B1 (en) * | 2014-09-12 | 2019-03-27 | MGI Tech Co., Ltd. | Isolated oligonucleotide and use thereof in nucleic acid sequencing |
| US10233490B2 (en) | 2014-11-21 | 2019-03-19 | Metabiotech Corporation | Methods for assembling and reading nucleic acid sequences from mixed populations |
| US9859394B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| US9618474B2 (en) | 2014-12-18 | 2017-04-11 | Edico Genome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| EP3235010A4 (en) | 2014-12-18 | 2018-08-29 | Agilome, Inc. | Chemically-sensitive field effect transistor |
| US10006910B2 (en) | 2014-12-18 | 2018-06-26 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems, and methods for manufacturing and using the same |
| US10020300B2 (en) | 2014-12-18 | 2018-07-10 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| US9857328B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems and methods for manufacturing and using the same |
| CN107002153B (zh) * | 2015-02-04 | 2020-10-27 | 深圳华大生命科学研究院 | 一种构建长片段测序文库的方法 |
| KR101651817B1 (ko) * | 2015-10-28 | 2016-08-29 | 대한민국 | Ngs 라이브러리 제작용 프라이머 세트 및 이를 이용한 ngs 라이브러리 제작방법 및 키트 |
| CN108699600A (zh) * | 2016-02-23 | 2018-10-23 | 诺维信公司 | 改进的新一代测序 |
| WO2017201081A1 (en) | 2016-05-16 | 2017-11-23 | Agilome, Inc. | Graphene fet devices, systems, and methods of using the same for sequencing nucleic acids |
| ES2870639T3 (es) | 2016-10-24 | 2021-10-27 | Geneinfosec Inc | Ocultación de información presente en los ácidos nucleicos |
| CN110167951A (zh) * | 2016-11-15 | 2019-08-23 | 奎斯特诊断投资有限责任公司 | 使用mitra尖端提取检测dna突变的方法 |
| JP2020501601A (ja) * | 2016-11-15 | 2020-01-23 | クエスト ダイアグノスティックス インヴェストメンツ エルエルシー | Ｍｉｔｒａチップ抽出を使用して嚢胞性線維症の変異を検出するための方法 |
| EP3626835A1 (en) | 2018-09-18 | 2020-03-25 | Sistemas Genómicos, S.L. | Method for genotypically identifying both alleles of at least one locus of a subject's hla gene |
| RU2703401C1 (ru) * | 2018-10-24 | 2019-10-16 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Кубанский государственный аграрный университет имени И.Т. Трубилина" | Тест-система для выявления и генотипирования РНК вируса репродуктивно-респираторного синдрома свиней |
| RU2703394C1 (ru) * | 2018-10-24 | 2019-10-16 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Кубанский государственный аграрный университет имени И.Т. Трубилина" | Способ выявления и генотипирования РНК вируса репродуктивно-респираторного синдрома свиней |
| FR3100820B1 (fr) | 2019-09-12 | 2024-06-28 | Bionobis | Procédé de génotypage adapté au traitement d’un grand nombre d’échantillons, notamment en cas de polymorphisme élevé |
| FR3106596B1 (fr) | 2020-01-27 | 2022-12-02 | Bionobis | Procede de genotypage hla simple et rapide |
| CN111235266B (zh) * | 2020-03-10 | 2023-12-01 | 广州医科大学附属第二医院 | Hla亚型检测试剂盒及其应用 |
| FR3110178B1 (fr) | 2020-05-18 | 2022-05-27 | Bionobis | Procédé de génotypage adapté au traitement simultané d’un grand nombre de patients |
| CN112553313A (zh) * | 2020-12-30 | 2021-03-26 | 武汉康圣达医学检验所有限公司 | 用于Sanger法的测序反应产物的变性方法 |
| KR102507110B1 (ko) * | 2022-02-15 | 2023-03-07 | 주식회사 네오젠티씨 | 주조직 적합성 복합체의 타입들을 분석하기 위한 방법 및 장치 |
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| EP0656065A1 (en) * | 1991-10-31 | 1995-06-07 | University Of Pittsburgh | Reverse dot blot hybridization using tandem head-to-tail monomers containing probes synthesized by staggered complementary primers |
| US5580730A (en) * | 1994-08-19 | 1996-12-03 | Olympus America, Inc. | Enzyme digestion method for the detection of amplified DNA |
| AU6321998A (en) | 1997-02-11 | 1998-08-26 | William H. Hildebrand | Class i sequence based typing of hla-a, -b, and -c alleles by direct dna sequencing |
| EP0953650A1 (en) * | 1998-04-20 | 1999-11-03 | Innogenetics N.V. | Method for typing of HLA alleles |
| CA2513535C (en) * | 2003-01-29 | 2012-06-12 | 454 Corporation | Bead emulsion nucleic acid amplification |
| US7300755B1 (en) * | 2003-05-12 | 2007-11-27 | Fred Hutchinson Cancer Research Center | Methods for haplotyping genomic DNA |
| WO2005042764A2 (en) | 2003-10-28 | 2005-05-12 | Dynal Biotech Llc | Primers, methods and kits for amplifying or detecting human leukocyte antigen alleles |
| US9365893B2 (en) * | 2005-05-10 | 2016-06-14 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon | Methods of mapping polymorphisms and polymorphism microarrays |
| EP2477029A1 (en) * | 2005-06-02 | 2012-07-18 | Fluidigm Corporation | Analysis using microfluidic partitioning devices |
| AU2006295556B2 (en) | 2005-09-29 | 2012-07-05 | Keygene N.V. | High throughput screening of mutagenized populations |
| US8071310B2 (en) | 2005-11-14 | 2011-12-06 | Keygene Nv | Method for the high throughput screening of transposon tagging populations and massive parallel sequence identification of insertion sites |
| DK3404114T3 (da) * | 2005-12-22 | 2021-06-28 | Keygene Nv | Fremgangsmåde til detektering af AFLP-baseret polymorfisme med højt gennemløb |
| US20110002948A1 (en) | 2006-06-09 | 2011-01-06 | Conexio 4 Pty Ltd | Identification of a nucleic acid molecule |
| US20100086914A1 (en) * | 2008-10-03 | 2010-04-08 | Roche Molecular Systems, Inc. | High resolution, high throughput hla genotyping by clonal sequencing |
| JP2011500041A (ja) * | 2007-10-16 | 2011-01-06 | エフ．ホフマン−ラ ロシュ アーゲー | クローナルシークエンシングによる高分解能かつ高効率のｈｌａ遺伝子型決定法 |
| RU2393231C1 (ru) * | 2008-12-29 | 2010-06-27 | Федеральное государственное учреждение здравоохранения "Российский научно-исследовательский противочумный институт "Микроб" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека ("РосНИПЧИ "Микроб") | Способ определения генетического родства штаммов холерных вибрионов методом секвенирования генов, фланкирующих кластер генов биосинтеза о-антигена |
| CN101921840B (zh) | 2010-06-30 | 2014-06-25 | 深圳华大基因科技有限公司 | 一种基于dna分子标签技术和dna不完全打断策略的pcr测序方法 |
| CN101921841B (zh) | 2010-06-30 | 2014-03-12 | 深圳华大基因科技有限公司 | 基于Illumina GA测序技术的HLA基因高分辨率分型方法 |
| CN101921842B (zh) | 2010-06-30 | 2013-08-07 | 深圳华大基因科技有限公司 | Hla-a,b基因分型用pcr引物及其使用方法 |
-
2011
- 2011-06-30 EP EP11800190.8A patent/EP2599877B1/en active Active
- 2011-06-30 MY MYPI2012005591A patent/MY173793A/en unknown
- 2011-06-30 RU RU2013103795/10A patent/RU2587606C2/ru active IP Right Revival
- 2011-06-30 AU AU2011274090A patent/AU2011274090B2/en active Active
- 2011-06-30 SG SG2012096616A patent/SG186876A1/en unknown
- 2011-06-30 CA CA2803940A patent/CA2803940C/en active Active
- 2011-06-30 JP JP2013516983A patent/JP5968879B2/ja active Active
- 2011-06-30 BR BR112012032586-8A patent/BR112012032586B1/pt active IP Right Grant
- 2011-06-30 WO PCT/CN2011/076688 patent/WO2012000445A1/zh not_active Ceased
- 2011-06-30 US US13/807,660 patent/US9957564B2/en active Active
- 2011-06-30 DK DK11800190.8T patent/DK2599877T3/da active
- 2011-06-30 KR KR1020137002332A patent/KR101709826B1/ko active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2599877B1 (en) | 2017-09-27 |
| WO2012000445A1 (zh) | 2012-01-05 |
| DK2599877T3 (da) | 2017-11-20 |
| JP2013529472A (ja) | 2013-07-22 |
| CA2803940C (en) | 2019-07-02 |
| AU2011274090B2 (en) | 2015-04-09 |
| EP2599877A1 (en) | 2013-06-05 |
| AU2011274090A1 (en) | 2013-02-07 |
| SG186876A1 (en) | 2013-02-28 |
| BR112012032586B1 (pt) | 2021-08-17 |
| RU2013103795A (ru) | 2014-08-20 |
| RU2587606C2 (ru) | 2016-06-20 |
| MY173793A (en) | 2020-02-24 |
| BR112012032586A2 (pt) | 2019-07-30 |
| EP2599877A4 (en) | 2014-01-01 |
| CA2803940A1 (en) | 2012-01-05 |
| KR101709826B1 (ko) | 2017-02-24 |
| US20130237432A1 (en) | 2013-09-12 |
| US9957564B2 (en) | 2018-05-01 |
| KR20130038353A (ko) | 2013-04-17 |
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