JP5968879B2 - Ｄｎａ分子タグ技術及びｄｎａ不完全断片化技術に基づいたｐｃｒシークエンシング法及びそれを用いたｈｌａ遺伝子タイピング法 - Google Patents
Ｄｎａ分子タグ技術及びｄｎａ不完全断片化技術に基づいたｐｃｒシークエンシング法及びそれを用いたｈｌａ遺伝子タイピング法 Download PDFInfo
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- JP5968879B2 JP5968879B2 JP2013516983A JP2013516983A JP5968879B2 JP 5968879 B2 JP5968879 B2 JP 5968879B2 JP 2013516983 A JP2013516983 A JP 2013516983A JP 2013516983 A JP2013516983 A JP 2013516983A JP 5968879 B2 JP5968879 B2 JP 5968879B2
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
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- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
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- Molecular Biology (AREA)
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- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010213721.2 | 2010-06-30 | ||
| CN201010213717.6A CN101921840B (zh) | 2010-06-30 | 2010-06-30 | 一种基于dna分子标签技术和dna不完全打断策略的pcr测序方法 |
| CN 201010213721 CN101921842B (zh) | 2010-06-30 | 2010-06-30 | Hla-a,b基因分型用pcr引物及其使用方法 |
| CN201010213717.6 | 2010-06-30 | ||
| CN201010213719.5A CN101921841B (zh) | 2010-06-30 | 2010-06-30 | 基于Illumina GA测序技术的HLA基因高分辨率分型方法 |
| CN201010213719.5 | 2010-06-30 | ||
| CNPCT/CN2010/002150 | 2010-12-24 | ||
| CNPCT/CN2010/002149 | 2010-12-24 | ||
| PCT/CN2010/002150 WO2012083506A1 (zh) | 2010-12-24 | 2010-12-24 | Hla-dqb1基因分型的方法及其相关引物 |
| PCT/CN2010/002149 WO2012083505A1 (zh) | 2010-12-24 | 2010-12-24 | Hla-c基因分型的方法及其相关引物 |
| PCT/CN2011/076688 WO2012000445A1 (zh) | 2010-06-30 | 2011-06-30 | 新的的pcr测序方法及其在hla基因分型中的应用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013529472A JP2013529472A (ja) | 2013-07-22 |
| JP2013529472A5 JP2013529472A5 (enExample) | 2014-08-14 |
| JP5968879B2 true JP5968879B2 (ja) | 2016-08-10 |
Family
ID=45401405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013516983A Active JP5968879B2 (ja) | 2010-06-30 | 2011-06-30 | Ｄｎａ分子タグ技術及びｄｎａ不完全断片化技術に基づいたｐｃｒシークエンシング法及びそれを用いたｈｌａ遺伝子タイピング法 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9957564B2 (enExample) |
| EP (1) | EP2599877B1 (enExample) |
| JP (1) | JP5968879B2 (enExample) |
| KR (1) | KR101709826B1 (enExample) |
| AU (1) | AU2011274090B2 (enExample) |
| BR (1) | BR112012032586B1 (enExample) |
| CA (1) | CA2803940C (enExample) |
| DK (1) | DK2599877T3 (enExample) |
| MY (1) | MY173793A (enExample) |
| RU (1) | RU2587606C2 (enExample) |
| SG (1) | SG186876A1 (enExample) |
| WO (1) | WO2012000445A1 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201708498VA (en) | 2013-04-17 | 2017-11-29 | Agency Science Tech & Res | Method for generating extended sequence reads |
| JP6308724B2 (ja) | 2013-05-09 | 2018-04-11 | ジェノダイブファーマ株式会社 | Ｈｌａ遺伝子のマルチプレックスｄｎａタイピング方法及びキット |
| US10508311B2 (en) * | 2013-08-26 | 2019-12-17 | The Translational Genomics Research Institute | Single molecule-overlapping read analysis for minor variant mutation detection in pathogen samples |
| GB201409282D0 (en) | 2014-05-23 | 2014-07-09 | Univ Sydney Tech | Sequencing process |
| CN106661636A (zh) * | 2014-09-05 | 2017-05-10 | 凯杰有限公司 | 衔接子连接的扩增子的制备 |
| WO2016037358A1 (zh) * | 2014-09-12 | 2016-03-17 | 深圳华大基因科技有限公司 | 分离的寡核苷酸及其在核酸测序中的用途 |
| US10233490B2 (en) | 2014-11-21 | 2019-03-19 | Metabiotech Corporation | Methods for assembling and reading nucleic acid sequences from mixed populations |
| US10020300B2 (en) | 2014-12-18 | 2018-07-10 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| US10429342B2 (en) | 2014-12-18 | 2019-10-01 | Edico Genome Corporation | Chemically-sensitive field effect transistor |
| US9859394B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| US9857328B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems and methods for manufacturing and using the same |
| US10006910B2 (en) | 2014-12-18 | 2018-06-26 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems, and methods for manufacturing and using the same |
| US9618474B2 (en) | 2014-12-18 | 2017-04-11 | Edico Genome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| WO2016124069A1 (zh) * | 2015-02-04 | 2016-08-11 | 深圳华大基因研究院 | 一种构建长片段测序文库的方法 |
| KR101651817B1 (ko) * | 2015-10-28 | 2016-08-29 | 대한민국 | Ngs 라이브러리 제작용 프라이머 세트 및 이를 이용한 ngs 라이브러리 제작방법 및 키트 |
| US20190048413A1 (en) * | 2016-02-23 | 2019-02-14 | Novozymes A/S | Improved next-generation sequencing |
| WO2017201081A1 (en) | 2016-05-16 | 2017-11-23 | Agilome, Inc. | Graphene fet devices, systems, and methods of using the same for sequencing nucleic acids |
| CN110312825A (zh) | 2016-10-24 | 2019-10-08 | 吉内恩福赛克公司 | 隐藏核酸内存在的信息 |
| WO2018093724A1 (en) | 2016-11-15 | 2018-05-24 | Quest Diagnostics Investments Llc | Methods for detecting dna mutations using mitra tip extraction |
| CA3044033A1 (en) | 2016-11-15 | 2018-05-24 | Quest Diagnostics Investments Llc | Methods for detecting cystic fibrosis mutations using mitra tip extraction |
| EP3626835A1 (en) | 2018-09-18 | 2020-03-25 | Sistemas Genómicos, S.L. | Method for genotypically identifying both alleles of at least one locus of a subject's hla gene |
| RU2703394C1 (ru) * | 2018-10-24 | 2019-10-16 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Кубанский государственный аграрный университет имени И.Т. Трубилина" | Способ выявления и генотипирования РНК вируса репродуктивно-респираторного синдрома свиней |
| RU2703401C1 (ru) * | 2018-10-24 | 2019-10-16 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Кубанский государственный аграрный университет имени И.Т. Трубилина" | Тест-система для выявления и генотипирования РНК вируса репродуктивно-респираторного синдрома свиней |
| FR3100820B1 (fr) | 2019-09-12 | 2024-06-28 | Bionobis | Procédé de génotypage adapté au traitement d’un grand nombre d’échantillons, notamment en cas de polymorphisme élevé |
| FR3106596B1 (fr) | 2020-01-27 | 2022-12-02 | Bionobis | Procede de genotypage hla simple et rapide |
| CN111235266B (zh) * | 2020-03-10 | 2023-12-01 | 广州医科大学附属第二医院 | Hla亚型检测试剂盒及其应用 |
| FR3110178B1 (fr) * | 2020-05-18 | 2022-05-27 | Bionobis | Procédé de génotypage adapté au traitement simultané d’un grand nombre de patients |
| CN112553313A (zh) * | 2020-12-30 | 2021-03-26 | 武汉康圣达医学检验所有限公司 | 用于Sanger法的测序反应产物的变性方法 |
| KR102507110B1 (ko) * | 2022-02-15 | 2023-03-07 | 주식회사 네오젠티씨 | 주조직 적합성 복합체의 타입들을 분석하기 위한 방법 및 장치 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO1993009245A1 (en) * | 1991-10-31 | 1993-05-13 | University Of Pittsburgh | Reverse dot blot hybridization using tandem head-to-tail monomers containing probes synthesized by staggered complementary primers |
| US5580730A (en) * | 1994-08-19 | 1996-12-03 | Olympus America, Inc. | Enzyme digestion method for the detection of amplified DNA |
| WO1998035059A1 (en) * | 1997-02-11 | 1998-08-13 | Hildebrand William H | Class i sequence based typing of hla-a, -b, and -c alleles by direct dna sequencing |
| EP0953650A1 (en) * | 1998-04-20 | 1999-11-03 | Innogenetics N.V. | Method for typing of HLA alleles |
| DE602004026033D1 (de) | 2003-01-29 | 2010-04-29 | 454 Corp | Zweiendige sequenzierung |
| US7300755B1 (en) | 2003-05-12 | 2007-11-27 | Fred Hutchinson Cancer Research Center | Methods for haplotyping genomic DNA |
| US20070111213A1 (en) | 2003-10-28 | 2007-05-17 | Lu Wang | Primers, methods and kits for amplifying or detecting human leukocyte antigen alleles |
| CA2612145A1 (en) * | 2005-05-10 | 2006-11-16 | Eric A. Johnson | Methods of mapping polymorphisms and polymorphism microarrays |
| EP2703499A1 (en) * | 2005-06-02 | 2014-03-05 | Fluidigm Corporation | Analysis using microfluidic partitioning devices to generate single cell samples |
| CA2910861C (en) * | 2005-09-29 | 2018-08-07 | Michael Josephus Theresia Van Eijk | High throughput screening of mutagenized populations |
| WO2007055568A1 (en) | 2005-11-14 | 2007-05-18 | Keygene N.V. | Method for high throughput screening of transposon tagging populations and massive parallel sequence identification of insertion sites |
| ES2882401T3 (es) * | 2005-12-22 | 2021-12-01 | Keygene Nv | Método de detección de polimorfismos basado en AFLP de alto rendimiento |
| WO2007140540A2 (en) | 2006-06-09 | 2007-12-13 | Conexio 4 Pty Ltd | Identification of a nucleic acid molecule |
| US20100086914A1 (en) * | 2008-10-03 | 2010-04-08 | Roche Molecular Systems, Inc. | High resolution, high throughput hla genotyping by clonal sequencing |
| EP2203567B1 (en) * | 2007-10-16 | 2011-05-11 | Roche Diagnostics GmbH | High resolution, high throughput hla genotyping by clonal sequencing |
| RU2393231C1 (ru) * | 2008-12-29 | 2010-06-27 | Федеральное государственное учреждение здравоохранения "Российский научно-исследовательский противочумный институт "Микроб" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека ("РосНИПЧИ "Микроб") | Способ определения генетического родства штаммов холерных вибрионов методом секвенирования генов, фланкирующих кластер генов биосинтеза о-антигена |
| CN101921840B (zh) | 2010-06-30 | 2014-06-25 | 深圳华大基因科技有限公司 | 一种基于dna分子标签技术和dna不完全打断策略的pcr测序方法 |
| CN101921841B (zh) * | 2010-06-30 | 2014-03-12 | 深圳华大基因科技有限公司 | 基于Illumina GA测序技术的HLA基因高分辨率分型方法 |
| CN101921842B (zh) | 2010-06-30 | 2013-08-07 | 深圳华大基因科技有限公司 | Hla-a,b基因分型用pcr引物及其使用方法 |
-
2011
- 2011-06-30 DK DK11800190.8T patent/DK2599877T3/da active
- 2011-06-30 MY MYPI2012005591A patent/MY173793A/en unknown
- 2011-06-30 SG SG2012096616A patent/SG186876A1/en unknown
- 2011-06-30 RU RU2013103795/10A patent/RU2587606C2/ru active IP Right Revival
- 2011-06-30 CA CA2803940A patent/CA2803940C/en active Active
- 2011-06-30 AU AU2011274090A patent/AU2011274090B2/en active Active
- 2011-06-30 JP JP2013516983A patent/JP5968879B2/ja active Active
- 2011-06-30 US US13/807,660 patent/US9957564B2/en active Active
- 2011-06-30 BR BR112012032586-8A patent/BR112012032586B1/pt active IP Right Grant
- 2011-06-30 EP EP11800190.8A patent/EP2599877B1/en active Active
- 2011-06-30 KR KR1020137002332A patent/KR101709826B1/ko active Active
- 2011-06-30 WO PCT/CN2011/076688 patent/WO2012000445A1/zh not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2013529472A (ja) | 2013-07-22 |
| DK2599877T3 (da) | 2017-11-20 |
| SG186876A1 (en) | 2013-02-28 |
| AU2011274090B2 (en) | 2015-04-09 |
| KR101709826B1 (ko) | 2017-02-24 |
| CA2803940A1 (en) | 2012-01-05 |
| BR112012032586B1 (pt) | 2021-08-17 |
| MY173793A (en) | 2020-02-24 |
| AU2011274090A1 (en) | 2013-02-07 |
| EP2599877B1 (en) | 2017-09-27 |
| WO2012000445A1 (zh) | 2012-01-05 |
| EP2599877A1 (en) | 2013-06-05 |
| RU2587606C2 (ru) | 2016-06-20 |
| US9957564B2 (en) | 2018-05-01 |
| EP2599877A4 (en) | 2014-01-01 |
| CA2803940C (en) | 2019-07-02 |
| KR20130038353A (ko) | 2013-04-17 |
| US20130237432A1 (en) | 2013-09-12 |
| RU2013103795A (ru) | 2014-08-20 |
| BR112012032586A2 (pt) | 2019-07-30 |
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