BR112012032586B1 - Métodos para determinar a sequência nucleotídica de um ácido nucléico de interesse e para determinar o genótipo hla em uma amostra - Google Patents
Métodos para determinar a sequência nucleotídica de um ácido nucléico de interesse e para determinar o genótipo hla em uma amostra Download PDFInfo
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- BR112012032586B1 BR112012032586B1 BR112012032586-8A BR112012032586A BR112012032586B1 BR 112012032586 B1 BR112012032586 B1 BR 112012032586B1 BR 112012032586 A BR112012032586 A BR 112012032586A BR 112012032586 B1 BR112012032586 B1 BR 112012032586B1
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- hla
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- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
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Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201010213721.2 | 2010-06-30 | ||
| CN201010213717.6A CN101921840B (zh) | 2010-06-30 | 2010-06-30 | 一种基于dna分子标签技术和dna不完全打断策略的pcr测序方法 |
| CN 201010213721 CN101921842B (zh) | 2010-06-30 | 2010-06-30 | Hla-a,b基因分型用pcr引物及其使用方法 |
| CN201010213717.6 | 2010-06-30 | ||
| CN201010213719.5 | 2010-06-30 | ||
| CN201010213719.5A CN101921841B (zh) | 2010-06-30 | 2010-06-30 | 基于Illumina GA测序技术的HLA基因高分辨率分型方法 |
| PCT/CN2010/002149 WO2012083505A1 (zh) | 2010-12-24 | 2010-12-24 | Hla-c基因分型的方法及其相关引物 |
| PCT/CN2010/002150 WO2012083506A1 (zh) | 2010-12-24 | 2010-12-24 | Hla-dqb1基因分型的方法及其相关引物 |
| CNPCT/CN2010/002149 | 2010-12-24 | ||
| CNPCT/CN2010/002150 | 2010-12-24 | ||
| PCT/CN2011/076688 WO2012000445A1 (zh) | 2010-06-30 | 2011-06-30 | 新的的pcr测序方法及其在hla基因分型中的应用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112012032586A2 BR112012032586A2 (pt) | 2019-07-30 |
| BR112012032586B1 true BR112012032586B1 (pt) | 2021-08-17 |
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| BR112012032586-8A BR112012032586B1 (pt) | 2010-06-30 | 2011-06-30 | Métodos para determinar a sequência nucleotídica de um ácido nucléico de interesse e para determinar o genótipo hla em uma amostra |
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| EP (1) | EP2599877B1 (enExample) |
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| MY (1) | MY173793A (enExample) |
| RU (1) | RU2587606C2 (enExample) |
| SG (1) | SG186876A1 (enExample) |
| WO (1) | WO2012000445A1 (enExample) |
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| WO2014171898A2 (en) | 2013-04-17 | 2014-10-23 | Agency For Science, Technology And Research | Method for generating extended sequence reads |
| JP6308724B2 (ja) | 2013-05-09 | 2018-04-11 | ジェノダイブファーマ株式会社 | Ｈｌａ遺伝子のマルチプレックスｄｎａタイピング方法及びキット |
| JP2016528913A (ja) * | 2013-08-26 | 2016-09-23 | ザ・トランスレーショナル・ジェノミクス・リサーチ・インスティチュート | 病原体試料におけるマイナー変異体突然変異検出のための単一分子重複読み取り分析 |
| GB201409282D0 (en) | 2014-05-23 | 2014-07-09 | Univ Sydney Tech | Sequencing process |
| WO2016034433A1 (en) * | 2014-09-05 | 2016-03-10 | Qiagen Gmbh | Preparation of adapter-ligated amplicons |
| CN105400864B (zh) * | 2014-09-12 | 2020-04-14 | 深圳华大基因股份有限公司 | 用于基于血液样品构建测序文库的方法及其在确定胎儿遗传异常中的用途 |
| JP6483249B2 (ja) * | 2014-09-12 | 2019-03-13 | エムジーアイ テック カンパニー リミテッドＭＧＩ Ｔｅｃｈ Ｃｏ．， Ｌｔｄ． | 単離されたオリゴヌクレオチドおよび核酸の配列決定におけるその使用 |
| US10233490B2 (en) | 2014-11-21 | 2019-03-19 | Metabiotech Corporation | Methods for assembling and reading nucleic acid sequences from mixed populations |
| US10006910B2 (en) | 2014-12-18 | 2018-06-26 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems, and methods for manufacturing and using the same |
| US10020300B2 (en) | 2014-12-18 | 2018-07-10 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| US9859394B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| US9618474B2 (en) | 2014-12-18 | 2017-04-11 | Edico Genome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| US9857328B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems and methods for manufacturing and using the same |
| WO2016100049A1 (en) | 2014-12-18 | 2016-06-23 | Edico Genome Corporation | Chemically-sensitive field effect transistor |
| CN107002153B (zh) * | 2015-02-04 | 2020-10-27 | 深圳华大生命科学研究院 | 一种构建长片段测序文库的方法 |
| KR101651817B1 (ko) | 2015-10-28 | 2016-08-29 | 대한민국 | Ngs 라이브러리 제작용 프라이머 세트 및 이를 이용한 ngs 라이브러리 제작방법 및 키트 |
| EP3420104A1 (en) * | 2016-02-23 | 2019-01-02 | Novozymes A/S | Improved next-generation sequencing |
| US10811539B2 (en) | 2016-05-16 | 2020-10-20 | Nanomedical Diagnostics, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| CN110312825A (zh) | 2016-10-24 | 2019-10-08 | 吉内恩福赛克公司 | 隐藏核酸内存在的信息 |
| US11473144B2 (en) | 2016-11-15 | 2022-10-18 | Quest Diagnostics Investments Llc | Methods for detecting cystic fibrosis mutations using mitra tip extraction |
| MX2019005683A (es) * | 2016-11-15 | 2019-10-30 | Quest Diagnostics Invest Llc | Metodos para detectar mutaciones de adn mediante el uso de extraccion con puntas mitra. |
| EP3626835A1 (en) | 2018-09-18 | 2020-03-25 | Sistemas Genómicos, S.L. | Method for genotypically identifying both alleles of at least one locus of a subject's hla gene |
| RU2703394C1 (ru) * | 2018-10-24 | 2019-10-16 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Кубанский государственный аграрный университет имени И.Т. Трубилина" | Способ выявления и генотипирования РНК вируса репродуктивно-респираторного синдрома свиней |
| RU2703401C1 (ru) * | 2018-10-24 | 2019-10-16 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Кубанский государственный аграрный университет имени И.Т. Трубилина" | Тест-система для выявления и генотипирования РНК вируса репродуктивно-респираторного синдрома свиней |
| FR3100820B1 (fr) | 2019-09-12 | 2024-06-28 | Bionobis | Procédé de génotypage adapté au traitement d’un grand nombre d’échantillons, notamment en cas de polymorphisme élevé |
| FR3106596B1 (fr) | 2020-01-27 | 2022-12-02 | Bionobis | Procede de genotypage hla simple et rapide |
| CN111235266B (zh) * | 2020-03-10 | 2023-12-01 | 广州医科大学附属第二医院 | Hla亚型检测试剂盒及其应用 |
| FR3110178B1 (fr) | 2020-05-18 | 2022-05-27 | Bionobis | Procédé de génotypage adapté au traitement simultané d’un grand nombre de patients |
| CN112553313A (zh) * | 2020-12-30 | 2021-03-26 | 武汉康圣达医学检验所有限公司 | 用于Sanger法的测序反应产物的变性方法 |
| KR102507110B1 (ko) * | 2022-02-15 | 2023-03-07 | 주식회사 네오젠티씨 | 주조직 적합성 복합체의 타입들을 분석하기 위한 방법 및 장치 |
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| EP0656065A1 (en) | 1991-10-31 | 1995-06-07 | University Of Pittsburgh | Reverse dot blot hybridization using tandem head-to-tail monomers containing probes synthesized by staggered complementary primers |
| US5580730A (en) | 1994-08-19 | 1996-12-03 | Olympus America, Inc. | Enzyme digestion method for the detection of amplified DNA |
| WO1998035059A1 (en) * | 1997-02-11 | 1998-08-13 | Hildebrand William H | Class i sequence based typing of hla-a, -b, and -c alleles by direct dna sequencing |
| EP0953650A1 (en) * | 1998-04-20 | 1999-11-03 | Innogenetics N.V. | Method for typing of HLA alleles |
| AU2004209426B2 (en) * | 2003-01-29 | 2008-04-17 | 454 Life Sciences Corporation | Method for preparing single-stranded DNA libraries |
| US7300755B1 (en) * | 2003-05-12 | 2007-11-27 | Fred Hutchinson Cancer Research Center | Methods for haplotyping genomic DNA |
| EP1711621A4 (en) | 2003-10-28 | 2008-06-18 | Dynal Biotech Llc | PRIMERS, METHODS AND KITS FOR THE AMPLIFICATION OR DETECTION OF HUMAN LEUKOCYTE ANTIGEN ALLELES |
| CA2612145A1 (en) * | 2005-05-10 | 2006-11-16 | Eric A. Johnson | Methods of mapping polymorphisms and polymorphism microarrays |
| US20090317798A1 (en) * | 2005-06-02 | 2009-12-24 | Heid Christian A | Analysis using microfluidic partitioning devices |
| DE602006011486D1 (de) | 2005-09-29 | 2010-02-11 | Keygene Nv | Screening mutagenisierter populationen mit hohem durchsatz |
| EP1960541B1 (en) * | 2005-11-14 | 2013-04-24 | Keygene N.V. | Method for high throughput screening of transposon tagging populations and massive parallel sequence identification of insertion sites |
| EP3045544A1 (en) * | 2005-12-22 | 2016-07-20 | Keygene N.V. | Method for high-throughput aflp-based polymorphism detection |
| CA2654729A1 (en) | 2006-06-09 | 2007-12-13 | Conexio 4 Pty Ltd | Identification of a nucleic acid molecule |
| CA2701411A1 (en) * | 2007-10-16 | 2009-04-23 | F. Hoffmann-La Roche Ag | High resolution, high throughput hla genotyping by clonal sequencing |
| US20100086914A1 (en) * | 2008-10-03 | 2010-04-08 | Roche Molecular Systems, Inc. | High resolution, high throughput hla genotyping by clonal sequencing |
| RU2393231C1 (ru) * | 2008-12-29 | 2010-06-27 | Федеральное государственное учреждение здравоохранения "Российский научно-исследовательский противочумный институт "Микроб" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека ("РосНИПЧИ "Микроб") | Способ определения генетического родства штаммов холерных вибрионов методом секвенирования генов, фланкирующих кластер генов биосинтеза о-антигена |
| CN101921840B (zh) | 2010-06-30 | 2014-06-25 | 深圳华大基因科技有限公司 | 一种基于dna分子标签技术和dna不完全打断策略的pcr测序方法 |
| CN101921841B (zh) * | 2010-06-30 | 2014-03-12 | 深圳华大基因科技有限公司 | 基于Illumina GA测序技术的HLA基因高分辨率分型方法 |
| CN101921842B (zh) * | 2010-06-30 | 2013-08-07 | 深圳华大基因科技有限公司 | Hla-a,b基因分型用pcr引物及其使用方法 |
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| US9957564B2 (en) | 2018-05-01 |
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| US20130237432A1 (en) | 2013-09-12 |
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| BR112012032586A2 (pt) | 2019-07-30 |
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| CA2803940C (en) | 2019-07-02 |
| DK2599877T3 (da) | 2017-11-20 |
| CA2803940A1 (en) | 2012-01-05 |
| EP2599877B1 (en) | 2017-09-27 |
| KR101709826B1 (ko) | 2017-02-24 |
| SG186876A1 (en) | 2013-02-28 |
| MY173793A (en) | 2020-02-24 |
| AU2011274090A1 (en) | 2013-02-07 |
| JP5968879B2 (ja) | 2016-08-10 |
| KR20130038353A (ko) | 2013-04-17 |
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