JP5960055B2 - 改変髄膜炎菌fHBPポリペプチド - Google Patents

改変髄膜炎菌fHBPポリペプチド Download PDF

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Publication number
JP5960055B2
JP5960055B2 JP2012535995A JP2012535995A JP5960055B2 JP 5960055 B2 JP5960055 B2 JP 5960055B2 JP 2012535995 A JP2012535995 A JP 2012535995A JP 2012535995 A JP2012535995 A JP 2012535995A JP 5960055 B2 JP5960055 B2 JP 5960055B2
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amino acid
seq
polypeptide
fhbp
acid sequence
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Expired - Fee Related
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JP2012535995A
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Japanese (ja)
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JP2014503172A (ja
JP2014503172A5 (enExample
Inventor
ルチア バンチ,
ルチア バンチ,
フランチェスカ カンティーニ,
フランチェスカ カンティーニ,
サラ ドラゴネッティ,
サラ ドラゴネッティ,
マリア アントニエッタ ジェンティレ,
マリア アントニエッタ ジェンティレ,
ダニエレ ベッジ,
ダニエレ ベッジ,
マリア スカーセッリ,
マリア スカーセッリ,
ピッツァ, マリアグラツィア
マリアグラツィア ピッツァ,
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ノバルティス アーゲー
ノバルティス アーゲー
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Publication of JP2014503172A5 publication Critical patent/JP2014503172A5/ja
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/095Neisseria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2012535995A 2009-10-27 2010-10-27 改変髄膜炎菌fHBPポリペプチド Expired - Fee Related JP5960055B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27997709P 2009-10-27 2009-10-27
US61/279,977 2009-10-27
PCT/IB2010/054865 WO2011051893A1 (en) 2009-10-27 2010-10-27 Modified meningococcal fhbp polypeptides

Related Child Applications (1)

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JP2015205429A Division JP2016040302A (ja) 2009-10-27 2015-10-19 改変髄膜炎菌fHBPポリペプチド

Publications (3)

Publication Number Publication Date
JP2014503172A JP2014503172A (ja) 2014-02-13
JP2014503172A5 JP2014503172A5 (enExample) 2014-04-03
JP5960055B2 true JP5960055B2 (ja) 2016-08-02

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JP2012535995A Expired - Fee Related JP5960055B2 (ja) 2009-10-27 2010-10-27 改変髄膜炎菌fHBPポリペプチド
JP2015205429A Pending JP2016040302A (ja) 2009-10-27 2015-10-19 改変髄膜炎菌fHBPポリペプチド

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Country Status (9)

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US (2) US20130022633A1 (enExample)
EP (1) EP2493499A1 (enExample)
JP (2) JP5960055B2 (enExample)
CN (1) CN102917730A (enExample)
AU (1) AU2010310985B2 (enExample)
BR (1) BR112012010531A2 (enExample)
CA (1) CA2779816A1 (enExample)
MX (1) MX2012004850A (enExample)
WO (1) WO2011051893A1 (enExample)

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SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
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KR20160034401A (ko) 2013-08-02 2016-03-29 칠드런즈 하스피틀 앤드 리써치 센터 앳 오클랜드 비-천연적으로 발생하는 인자 h 결합 단백질(fhbp) 및 이의 사용 방법
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MX373277B (es) 2014-02-28 2020-05-20 Glaxosmithkline Biologicals Sa Polipeptidos fhbp meningococicos modificados.
AR102324A1 (es) * 2014-07-17 2017-02-22 Glaxosmithkline Biologicals Sa Polipéptidos fhbp (proteína de unión al factor h) meningocócicos modificados
MX2017000775A (es) 2014-07-17 2017-05-04 Glaxosmithkline Biologicals Sa Vacunas de meningococos.
CN106715464B (zh) * 2014-07-23 2021-03-16 奥克兰儿童医院及研究中心 因子h结合蛋白变体及其使用方法
US10232029B2 (en) 2014-12-09 2019-03-19 Sanofi Pasteur Compositions comprising N. meningitidis proteins
CN107249626A (zh) 2015-02-19 2017-10-13 辉瑞大药厂 脑膜炎奈瑟球菌组合物及其方法
GB201614687D0 (en) * 2016-08-31 2016-10-12 Univ Oxford Innovation Ltd fHbp scaffold
PL3506935T3 (pl) 2016-09-02 2024-06-10 Sanofi Pasteur, Inc. Szczepionka przeciwko Neisseria meningitidis
EP3312192B1 (en) * 2016-10-24 2023-02-22 BiOMVis Srl Immunogenic compositions containing bacterial outer membrane vesicles
PE20191107A1 (es) 2017-01-31 2019-08-26 Pfizer Composiciones de neisseria meningitidis y metodos respectivos
EP3607967A1 (en) * 2018-08-09 2020-02-12 GlaxoSmithKline Biologicals S.A. Modified meningococcal fhbp polypeptides
CA3155669A1 (en) 2019-09-27 2021-04-01 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
WO2022178196A1 (en) 2021-02-19 2022-08-25 Sanofi Pasteur Inc. Meningococcal b recombinant vaccine
TW202423477A (zh) 2022-08-03 2024-06-16 美商賽諾菲巴斯德公司 針對腦膜炎奈瑟氏菌b的含佐劑免疫原性組成物
CN120241991B (zh) * 2025-06-05 2025-12-23 北京绿竹生物技术股份有限公司 一种新型的b群流脑外膜蛋白双功能载体

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MX2012004850A (es) 2012-05-22
JP2014503172A (ja) 2014-02-13
US20130022633A1 (en) 2013-01-24
AU2010310985B2 (en) 2014-11-06
US20140348869A1 (en) 2014-11-27
EP2493499A1 (en) 2012-09-05
WO2011051893A1 (en) 2011-05-05
CN102917730A (zh) 2013-02-06

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