CA2779816A1 - Modified meningococcal fhbp polypeptides - Google Patents
Modified meningococcal fhbp polypeptides Download PDFInfo
- Publication number
- CA2779816A1 CA2779816A1 CA2779816A CA2779816A CA2779816A1 CA 2779816 A1 CA2779816 A1 CA 2779816A1 CA 2779816 A CA2779816 A CA 2779816A CA 2779816 A CA2779816 A CA 2779816A CA 2779816 A1 CA2779816 A1 CA 2779816A1
- Authority
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- Canada
- Prior art keywords
- seq
- amino acid
- polypeptide
- fhbp
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27997709P | 2009-10-27 | 2009-10-27 | |
| US61/279,977 | 2009-10-27 | ||
| PCT/IB2010/054865 WO2011051893A1 (en) | 2009-10-27 | 2010-10-27 | Modified meningococcal fhbp polypeptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2779816A1 true CA2779816A1 (en) | 2011-05-05 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2779816A Abandoned CA2779816A1 (en) | 2009-10-27 | 2010-10-27 | Modified meningococcal fhbp polypeptides |
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| Country | Link |
|---|---|
| US (2) | US20130022633A1 (enExample) |
| EP (1) | EP2493499A1 (enExample) |
| JP (2) | JP5960055B2 (enExample) |
| CN (1) | CN102917730A (enExample) |
| AU (1) | AU2010310985B2 (enExample) |
| BR (1) | BR112012010531A2 (enExample) |
| CA (1) | CA2779816A1 (enExample) |
| MX (1) | MX2012004850A (enExample) |
| WO (1) | WO2011051893A1 (enExample) |
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| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| GB0227346D0 (en) | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
| PL2411048T3 (pl) | 2009-03-24 | 2020-11-16 | Glaxosmithkline Biologicals Sa | Adjuwantowe meningokokowe białko wiążące czynnik h |
| EP2544714A1 (en) * | 2010-03-10 | 2013-01-16 | GlaxoSmithKline Biologicals S.A. | Vaccine composition |
| WO2011126863A1 (en) | 2010-03-30 | 2011-10-13 | Children's Hospital & Research Center Oakland | Factor h binding proteins (fhbp) with altered properties and methods of use thereof |
| RU2580620C2 (ru) | 2010-08-23 | 2016-04-10 | ВАЙЕТ ЭлЭлСи | СТАБИЛЬНЫЕ КОМПОЗИЦИИ АНТИГЕНОВ Neisseria meningitidis rLP2086 |
| WO2012032489A1 (en) | 2010-09-10 | 2012-03-15 | Wyeth Llc | Non-lipidated variants of neisseria meningitidis orf2086 antigens |
| CA2865745C (en) | 2012-03-09 | 2018-01-09 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| MX357538B (es) * | 2012-06-14 | 2018-07-13 | Novartis Ag | Vacunas para meningococo de serogrupo x. |
| HK1205138A1 (en) | 2012-07-27 | 2015-12-11 | Institut National De La Santé Et De La Recherche Médicale (Inserm) | Cd147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia |
| RU2662970C2 (ru) * | 2012-09-18 | 2018-07-31 | Новартис Аг | Везикулы наружной мембраны |
| US9802987B2 (en) | 2013-03-08 | 2017-10-31 | Pfizer Inc. | Immunogenic fusion polypeptides |
| US20160030544A1 (en) * | 2013-03-14 | 2016-02-04 | Isis Innovation Limited | Immunogenic composition to neisseria |
| US9914756B2 (en) | 2013-08-02 | 2018-03-13 | Children's Hospital & Research Center At Oakland | Non-naturally occurring factor H binding proteins (fHbp) and methods of use thereof |
| RU2662968C2 (ru) | 2013-09-08 | 2018-07-31 | Пфайзер Инк. | Иммуногенная композиция против neisseria meningitidis (варианты) |
| CA2940447C (en) | 2014-02-28 | 2023-07-11 | Glaxosmithkline Biologicals Sa | Modified meningococcal fhbp polypeptides |
| US11707513B2 (en) | 2014-07-17 | 2023-07-25 | Glaxosmithkline Biologicals Sa | Meningococcus vaccines |
| SG11201610945PA (en) * | 2014-07-17 | 2017-01-27 | Glaxosmithkline Biolog Sa | Modified meningococcal fhbp polypeptides |
| CN119613509A (zh) * | 2014-07-23 | 2025-03-14 | 奥克兰儿童医院及研究中心 | 因子h结合蛋白变体及其使用方法 |
| EP3229835A1 (en) | 2014-12-09 | 2017-10-18 | Sanofi Pasteur | Compositions comprising n. meningitidis proteins |
| AU2016221318B2 (en) | 2015-02-19 | 2020-06-25 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| GB201614687D0 (en) * | 2016-08-31 | 2016-10-12 | Univ Oxford Innovation Ltd | fHbp scaffold |
| RS65362B1 (sr) | 2016-09-02 | 2024-04-30 | Sanofi Pasteur Inc | Vakcina protiv neisseria meningitidis |
| EP3312192B1 (en) * | 2016-10-24 | 2023-02-22 | BiOMVis Srl | Immunogenic compositions containing bacterial outer membrane vesicles |
| US10183070B2 (en) | 2017-01-31 | 2019-01-22 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| EP3607967A1 (en) | 2018-08-09 | 2020-02-12 | GlaxoSmithKline Biologicals S.A. | Modified meningococcal fhbp polypeptides |
| EP4034157A1 (en) | 2019-09-27 | 2022-08-03 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| CA3211240A1 (en) | 2021-02-19 | 2022-08-25 | Sanofi Pasteur Inc. | Meningococcal b recombinant vaccine |
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2010
- 2010-10-27 BR BR112012010531A patent/BR112012010531A2/pt not_active IP Right Cessation
- 2010-10-27 US US13/504,476 patent/US20130022633A1/en not_active Abandoned
- 2010-10-27 MX MX2012004850A patent/MX2012004850A/es unknown
- 2010-10-27 WO PCT/IB2010/054865 patent/WO2011051893A1/en not_active Ceased
- 2010-10-27 AU AU2010310985A patent/AU2010310985B2/en not_active Ceased
- 2010-10-27 CN CN201080060450XA patent/CN102917730A/zh active Pending
- 2010-10-27 CA CA2779816A patent/CA2779816A1/en not_active Abandoned
- 2010-10-27 JP JP2012535995A patent/JP5960055B2/ja not_active Expired - Fee Related
- 2010-10-27 EP EP10782038A patent/EP2493499A1/en not_active Withdrawn
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2014
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2015
- 2015-10-19 JP JP2015205429A patent/JP2016040302A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2493499A1 (en) | 2012-09-05 |
| MX2012004850A (es) | 2012-05-22 |
| JP2016040302A (ja) | 2016-03-24 |
| AU2010310985B2 (en) | 2014-11-06 |
| JP2014503172A (ja) | 2014-02-13 |
| JP5960055B2 (ja) | 2016-08-02 |
| WO2011051893A1 (en) | 2011-05-05 |
| AU2010310985A1 (en) | 2012-05-24 |
| CN102917730A (zh) | 2013-02-06 |
| US20130022633A1 (en) | 2013-01-24 |
| US20140348869A1 (en) | 2014-11-27 |
| BR112012010531A2 (pt) | 2019-09-24 |
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