JP5710269B2 - アザインドリジン類と使用方法 - Google Patents

アザインドリジン類と使用方法 Download PDF

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Publication number
JP5710269B2
JP5710269B2 JP2010539862A JP2010539862A JP5710269B2 JP 5710269 B2 JP5710269 B2 JP 5710269B2 JP 2010539862 A JP2010539862 A JP 2010539862A JP 2010539862 A JP2010539862 A JP 2010539862A JP 5710269 B2 JP5710269 B2 JP 5710269B2
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JP
Japan
Prior art keywords
alkyl
acid
compound
formula
fluoro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP2010539862A
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English (en)
Japanese (ja)
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JP2011507896A5 (https=
JP2011507896A (ja
Inventor
スティーヴン プライス，
スティーヴン プライス，
ロバート ヒールド，
ロバート ヒールド，
ピーター ヒューイット，
ピーター ヒューイット，
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Genentech Inc
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Genentech Inc
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Publication of JP2011507896A publication Critical patent/JP2011507896A/ja
Publication of JP2011507896A5 publication Critical patent/JP2011507896A5/ja
Application granted granted Critical
Publication of JP5710269B2 publication Critical patent/JP5710269B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2010539862A 2007-12-21 2008-12-19 アザインドリジン類と使用方法 Expired - Fee Related JP5710269B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1594207P 2007-12-21 2007-12-21
US61/015,942 2007-12-21
PCT/US2008/087626 WO2009082687A1 (en) 2007-12-21 2008-12-19 Azaindolizines and methods of use

Publications (3)

Publication Number Publication Date
JP2011507896A JP2011507896A (ja) 2011-03-10
JP2011507896A5 JP2011507896A5 (https=) 2012-01-19
JP5710269B2 true JP5710269B2 (ja) 2015-04-30

Family

ID=40352017

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010539862A Expired - Fee Related JP5710269B2 (ja) 2007-12-21 2008-12-19 アザインドリジン類と使用方法

Country Status (12)

Country Link
US (1) US8486963B2 (https=)
EP (1) EP2220092B1 (https=)
JP (1) JP5710269B2 (https=)
KR (1) KR20100099185A (https=)
CN (1) CN101945875B (https=)
AU (1) AU2008340247B2 (https=)
BR (1) BRPI0819505A2 (https=)
CA (1) CA2708176A1 (https=)
ES (1) ES2387707T3 (https=)
IL (1) IL206125A (https=)
NZ (1) NZ586575A (https=)
WO (1) WO2009082687A1 (https=)

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PT3624796T (pt) 2017-05-19 2025-06-02 Nflection Therapeutics Inc Compostos de pirrolopiridina-anilina para tratamento de distúrbios dérmicos
JP7237941B2 (ja) 2017-05-19 2023-03-13 エヌフレクション セラピューティクス インコーポレイテッド 皮膚障害の処置用の融合複素環式芳香族アニリン化合物
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WO2021094210A1 (en) 2019-11-12 2021-05-20 Bayer Aktiengesellschaft Substituted pyrazine carboxamide derivatives as prostaglandin ep3 receptor antagonists
US20260048075A1 (en) 2022-08-10 2026-02-19 Vib Vzw Inhibition of TCF4/ITF2 in the Treatment of Cancer
WO2026019990A1 (en) 2024-07-18 2026-01-22 Genentech, Inc. Methods of treating cancer with anti-ccr8/anti-cd3 bispecific antibodies

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Also Published As

Publication number Publication date
US20110142826A1 (en) 2011-06-16
IL206125A (en) 2015-08-31
IL206125A0 (en) 2010-11-30
ES2387707T3 (es) 2012-09-28
WO2009082687A1 (en) 2009-07-02
US8486963B2 (en) 2013-07-16
CN101945875B (zh) 2013-04-24
CA2708176A1 (en) 2009-07-02
AU2008340247A1 (en) 2009-07-02
EP2220092B1 (en) 2012-06-06
BRPI0819505A2 (pt) 2017-04-04
KR20100099185A (ko) 2010-09-10
CN101945875A (zh) 2011-01-12
JP2011507896A (ja) 2011-03-10
EP2220092A1 (en) 2010-08-25
NZ586575A (en) 2012-03-30
AU2008340247B2 (en) 2012-11-15
RU2010130315A (ru) 2012-01-27

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