JP5607038B2 - チアゾリルピペリジン誘導体 - Google Patents
チアゾリルピペリジン誘導体 Download PDFInfo
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- JP5607038B2 JP5607038B2 JP2011515144A JP2011515144A JP5607038B2 JP 5607038 B2 JP5607038 B2 JP 5607038B2 JP 2011515144 A JP2011515144 A JP 2011515144A JP 2011515144 A JP2011515144 A JP 2011515144A JP 5607038 B2 JP5607038 B2 JP 5607038B2
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/28—Radicals substituted by nitrogen atoms
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- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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| DE102008029734.8 | 2008-06-23 | ||
| DE102008029734A DE102008029734A1 (de) | 2008-06-23 | 2008-06-23 | Thiazolyl-piperidinderivate |
| PCT/EP2009/003817 WO2009156041A2 (de) | 2008-06-23 | 2009-05-28 | Thiazolyl-piperidinderivate |
Publications (3)
| Publication Number | Publication Date |
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| JP2011525502A JP2011525502A (ja) | 2011-09-22 |
| JP2011525502A5 JP2011525502A5 (enExample) | 2012-07-12 |
| JP5607038B2 true JP5607038B2 (ja) | 2014-10-15 |
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| JP2011515144A Expired - Fee Related JP5607038B2 (ja) | 2008-06-23 | 2009-05-28 | チアゾリルピペリジン誘導体 |
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| EP (1) | EP2313403B1 (enExample) |
| JP (1) | JP5607038B2 (enExample) |
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| CN (1) | CN102066367A (enExample) |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2013514287A (ja) * | 2009-12-17 | 2013-04-25 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | スフィンゴシンキナーゼの阻害薬 |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0811978A2 (pt) * | 2007-06-01 | 2014-11-18 | Hoffmann La Roche | Compostos, processo para a sua manufatura, composições farmacêuticas que os compreendem, método para o tratamento terapêutico e/ou profilático de enfermidades que são moduladas por inibidores de l-cpt1 e uso dos compostos |
| CA2806734A1 (en) | 2010-07-26 | 2012-02-09 | Biomatrica, Inc. | Compositions for stabilizing dna, rna and proteins in saliva and other biological samples during shipping and storage at ambient temperatures |
| GB201020161D0 (en) | 2010-11-26 | 2011-01-12 | Almac Discovery Ltd | Pharmaceutical compounds |
| GB2493142A (en) | 2011-07-20 | 2013-01-30 | Johann Wolfgang Goethe Uni T Frankfurt | Ceramide and ceramide synthase in the diagnosis and treatment of multiple sclerosis |
| CN104144927B (zh) * | 2011-12-23 | 2016-08-24 | 明治制果药业株式会社 | S1p受体调节剂 |
| EP2934572A4 (en) | 2012-12-20 | 2016-11-23 | Biomatrica Inc | FORMULATIONS AND METHODS FOR STABILIZING PCR REAGENTS |
| WO2014157382A1 (ja) * | 2013-03-29 | 2014-10-02 | 味の素株式会社 | スフィンゴシンキナーゼ阻害剤 |
| CN113826612B (zh) | 2014-06-10 | 2022-11-22 | 生物马特里卡公司 | 在环境温度下稳定凝血细胞 |
| WO2016019312A2 (en) * | 2014-07-31 | 2016-02-04 | Oregon Health & Science University | Vmat inhibitory compounds |
| WO2016085933A1 (en) | 2014-11-24 | 2016-06-02 | The Board Of Trustees Of The University Of Illinois | Method of preventing or treating a pulmonary disease or condition |
| BR112018011639A2 (pt) | 2015-12-08 | 2018-11-27 | Biomatrica Inc | redução de taxa de sedimentação de eritrócitos |
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| GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
| BR9707495A (pt) | 1996-02-13 | 1999-07-27 | Zeneca Ltd | Derivado de quinazolina processo para a preparação do mesmo composição farmacêutica e processo para a produç o de um efeito antiangiogênico e/ou de redução de permeabilidade vascular em um animal de sangue quente |
| JP4464466B2 (ja) | 1996-03-05 | 2010-05-19 | アストラゼネカ・ユーケイ・リミテッド | ４―アニリノキナゾリン誘導体 |
| GB9718972D0 (en) | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
| GB9714249D0 (en) | 1997-07-08 | 1997-09-10 | Angiogene Pharm Ltd | Vascular damaging agents |
| GB9900334D0 (en) | 1999-01-07 | 1999-02-24 | Angiogene Pharm Ltd | Tricylic vascular damaging agents |
| GB9900752D0 (en) | 1999-01-15 | 1999-03-03 | Angiogene Pharm Ltd | Benzimidazole vascular damaging agents |
| IL152682A0 (en) | 2000-05-31 | 2003-06-24 | Astrazeneca Ab | Indole derivatives with vascular damaging activity |
| JP2004502766A (ja) | 2000-07-07 | 2004-01-29 | アンギオジェン・ファーマシューティカルズ・リミテッド | 血管損傷剤としてのコルヒノール誘導体 |
| CA2410562A1 (en) | 2000-07-07 | 2002-01-31 | Angiogene Pharmaceuticals Limited | Colchinol derivatives as angiogenesis inhibitors |
| CA2613122C (en) | 2005-06-29 | 2013-01-22 | Compumedics Limited | Sensor assembly with conductive bridge |
| CA2617788A1 (en) | 2005-08-04 | 2007-02-15 | Apogee Biotechnology Corporation | Sphingosine kinase inhibitors and methods of their use |
| EP1945635B1 (en) | 2005-08-18 | 2009-05-06 | F.Hoffmann-La Roche Ag | Thiazolyl piperidine derivatives useful as h3 receptor modulators |
| WO2007064553A2 (en) | 2005-11-29 | 2007-06-07 | Merck & Co., Inc. | Thiazole derivatives as cxcr3 receptor modulators |
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2008
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2009
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2013514287A (ja) * | 2009-12-17 | 2013-04-25 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | スフィンゴシンキナーゼの阻害薬 |
Also Published As
| Publication number | Publication date |
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| CA2728851A1 (en) | 2009-12-30 |
| WO2009156041A3 (de) | 2010-06-10 |
| AR072192A1 (es) | 2010-08-11 |
| AU2009262631A1 (en) | 2009-12-30 |
| EP2313403A2 (de) | 2011-04-27 |
| KR20110031349A (ko) | 2011-03-25 |
| EA201100035A1 (ru) | 2011-08-30 |
| US8436186B2 (en) | 2013-05-07 |
| EP2313403B1 (de) | 2015-04-08 |
| ZA201100566B (en) | 2011-10-26 |
| MX2010013915A (es) | 2011-02-21 |
| US20110105505A1 (en) | 2011-05-05 |
| BRPI0913234A2 (pt) | 2016-01-19 |
| DE102008029734A1 (de) | 2009-12-24 |
| CN102066367A (zh) | 2011-05-18 |
| AU2009262631B2 (en) | 2013-08-22 |
| IL210164A0 (en) | 2011-03-31 |
| WO2009156041A2 (de) | 2009-12-30 |
| JP2011525502A (ja) | 2011-09-22 |
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