JP4937899B2 - ＶＥＧＦを標的とするｉＲＮＡ物質 - Google Patents

ＶＥＧＦを標的とするｉＲＮＡ物質 Download PDF

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Publication number
JP4937899B2
JP4937899B2 JP2007503050A JP2007503050A JP4937899B2 JP 4937899 B2 JP4937899 B2 JP 4937899B2 JP 2007503050 A JP2007503050 A JP 2007503050A JP 2007503050 A JP2007503050 A JP 2007503050A JP 4937899 B2 JP4937899 B2 JP 4937899B2
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irna
sequence
irna agent
sirna
rna
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JP2007528736A5 (https=
JP2007528736A (ja
Inventor
フージュロールズ、アントニン デ
フランク−カメネツキー、マリア
マノハラン、ムシア
ジー． ラジェーブ、カランソータイル
ハドビガー、フィリップ
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Alnylam Pharmaceuticals Inc
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Alnylam Pharmaceuticals Inc
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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JP2007503050A 2004-03-12 2005-03-11 ＶＥＧＦを標的とするｉＲＮＡ物質 Expired - Fee Related JP4937899B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US55262004P 2004-03-12 2004-03-12
US60/552,620 2004-03-12
US55982404P 2004-04-05 2004-04-05
US60/559,824 2004-04-05
US64719105P 2005-01-25 2005-01-25
US60/647,191 2005-01-25
PCT/US2005/008182 WO2005089224A2 (en) 2004-03-12 2005-03-11 iRNA AGENTS TARGETING VEGF

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JP2011121050A Division JP5502025B2 (ja) 2004-03-12 2011-05-30 ＶＥＧＦを標的とするｉＲＮＡ物質

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JP2007528736A JP2007528736A (ja) 2007-10-18
JP2007528736A5 JP2007528736A5 (https=) 2009-03-26
JP4937899B2 true JP4937899B2 (ja) 2012-05-23

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JP2007503050A Expired - Fee Related JP4937899B2 (ja) 2004-03-12 2005-03-11 ＶＥＧＦを標的とするｉＲＮＡ物質
JP2011121050A Expired - Lifetime JP5502025B2 (ja) 2004-03-12 2011-05-30 ＶＥＧＦを標的とするｉＲＮＡ物質
JP2014025057A Withdrawn JP2014094020A (ja) 2004-03-12 2014-02-13 ＶＥＧＦを標的とするｉＲＮＡ物質
JP2016088971A Pending JP2016135144A (ja) 2004-03-12 2016-04-27 ＶＥＧＦを標的とするｉＲＮＡ物質

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JP2011121050A Expired - Lifetime JP5502025B2 (ja) 2004-03-12 2011-05-30 ＶＥＧＦを標的とするｉＲＮＡ物質
JP2014025057A Withdrawn JP2014094020A (ja) 2004-03-12 2014-02-13 ＶＥＧＦを標的とするｉＲＮＡ物質
JP2016088971A Pending JP2016135144A (ja) 2004-03-12 2016-04-27 ＶＥＧＦを標的とするｉＲＮＡ物質

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US (5) US7947659B2 (https=)
EP (4) EP2899278A1 (https=)
JP (4) JP4937899B2 (https=)
AU (2) AU2005222902B2 (https=)
CA (1) CA2559161C (https=)
ES (1) ES2423060T3 (https=)
WO (1) WO2005089224A2 (https=)

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FR2832154B1 (fr) * 2001-11-09 2007-03-16 Centre Nat Rech Scient Oligonucleotides inhibiteurs et leur utilisation pour reprimer specifiquement un gene
CA2482904A1 (en) * 2002-04-18 2003-10-23 Lynkeus Biotech Gmbh Means and methods for the specific modulation of target genes in the cns and the eye and methods for their identification
US7148342B2 (en) 2002-07-24 2006-12-12 The Trustees Of The University Of Pennyslvania Compositions and methods for sirna inhibition of angiogenesis
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