JP4907082B2 - ウイルス阻害剤 - Google Patents

ウイルス阻害剤 Download PDF

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Publication number
JP4907082B2
JP4907082B2 JP2004518295A JP2004518295A JP4907082B2 JP 4907082 B2 JP4907082 B2 JP 4907082B2 JP 2004518295 A JP2004518295 A JP 2004518295A JP 2004518295 A JP2004518295 A JP 2004518295A JP 4907082 B2 JP4907082 B2 JP 4907082B2
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JP
Japan
Prior art keywords
imidazo
pyridine
alkyl
methyl
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP2004518295A
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English (en)
Japanese (ja)
Other versions
JP2005537248A5 (enExample
JP2005537248A (ja
Inventor
ネイツ，ヨハン
ピュルスティンガー，ゲルハルト
ドゥ・クレルク，エリック
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Katholieke Universiteit Leuven
Original Assignee
Katholieke Universiteit Leuven
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0313251A external-priority patent/GB0313251D0/en
Application filed by Katholieke Universiteit Leuven filed Critical Katholieke Universiteit Leuven
Publication of JP2005537248A publication Critical patent/JP2005537248A/ja
Publication of JP2005537248A5 publication Critical patent/JP2005537248A5/ja
Application granted granted Critical
Publication of JP4907082B2 publication Critical patent/JP4907082B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2004518295A 2002-07-03 2003-07-03 ウイルス阻害剤 Expired - Fee Related JP4907082B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB0215293.2A GB0215293D0 (en) 2002-07-03 2002-07-03 Viral inhibitors
GB0215293.2 2002-07-03
GB0313251.1 2003-06-10
GB0313251A GB0313251D0 (en) 2003-06-10 2003-06-10 Viral inhibitors
PCT/BE2003/000117 WO2004005286A2 (en) 2002-07-03 2003-07-03 Viral inhibitors

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2010174929A Division JP5174097B2 (ja) 2002-07-03 2010-08-03 ウイルス阻害剤

Publications (3)

Publication Number Publication Date
JP2005537248A JP2005537248A (ja) 2005-12-08
JP2005537248A5 JP2005537248A5 (enExample) 2010-09-24
JP4907082B2 true JP4907082B2 (ja) 2012-03-28

Family

ID=30117086

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2004518295A Expired - Fee Related JP4907082B2 (ja) 2002-07-03 2003-07-03 ウイルス阻害剤
JP2010174929A Expired - Fee Related JP5174097B2 (ja) 2002-07-03 2010-08-03 ウイルス阻害剤

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2010174929A Expired - Fee Related JP5174097B2 (ja) 2002-07-03 2010-08-03 ウイルス阻害剤

Country Status (21)

Country Link
US (2) US7737162B2 (enExample)
EP (2) EP2332938B1 (enExample)
JP (2) JP4907082B2 (enExample)
KR (2) KR101131591B1 (enExample)
CN (1) CN1328279C (enExample)
AT (1) ATE522528T1 (enExample)
AU (2) AU2003243846B9 (enExample)
BR (2) BR122018077110B1 (enExample)
CA (1) CA2491243C (enExample)
CY (1) CY1112042T1 (enExample)
DK (1) DK1521754T3 (enExample)
EA (1) EA013562B1 (enExample)
ES (2) ES2525483T3 (enExample)
GB (1) GB0215293D0 (enExample)
IL (1) IL166055A (enExample)
MX (1) MXPA04012965A (enExample)
NO (1) NO330766B1 (enExample)
NZ (1) NZ537473A (enExample)
PT (2) PT2332938E (enExample)
SI (1) SI1521754T1 (enExample)
WO (1) WO2004005286A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010248262A (ja) * 2002-07-03 2010-11-04 Ku Leuven Research & Development ウイルス阻害剤
JP2011148835A (ja) * 2003-12-22 2011-08-04 Katholieke Univ Leuven Ku Leuven R&D イミダゾ［４，５−ｃ］ピリジン化合物および抗ウイルス治療の方法

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JP2013526581A (ja) 2010-05-21 2013-06-24 ギリアード サイエンシーズ， インコーポレイテッド ヘテロ環式フラビウイルス科ウイルス阻害剤
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