SI1521754T1 - Virusni inhibitorji - Google Patents
Virusni inhibitorjiInfo
- Publication number
- SI1521754T1 SI1521754T1 SI200332077T SI200332077T SI1521754T1 SI 1521754 T1 SI1521754 T1 SI 1521754T1 SI 200332077 T SI200332077 T SI 200332077T SI 200332077 T SI200332077 T SI 200332077T SI 1521754 T1 SI1521754 T1 SI 1521754T1
- Authority
- SI
- Slovenia
- Prior art keywords
- viral inhibitors
- imidazo
- virus
- class
- relates
- Prior art date
Links
- 239000003443 antiviral agent Substances 0.000 title 1
- UBOOKRVGOBKDMM-UHFFFAOYSA-N 3h-imidazo[4,5-c]pyridine Chemical class C1=NC=C2NC=NC2=C1 UBOOKRVGOBKDMM-UHFFFAOYSA-N 0.000 abstract 2
- 241000700605 Viruses Species 0.000 abstract 2
- 241000710780 Bovine viral diarrhea virus 1 Species 0.000 abstract 1
- 241000710781 Flaviviridae Species 0.000 abstract 1
- 241000709664 Picornaviridae Species 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- PPBOKXIGFIBOGK-BDTUAEFFSA-N bvdv Chemical compound C([C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)C(C)C)[C@@H](C)CC)C1=CN=CN1 PPBOKXIGFIBOGK-BDTUAEFFSA-N 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000010076 replication Effects 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0215293.2A GB0215293D0 (en) | 2002-07-03 | 2002-07-03 | Viral inhibitors |
| GB0313251A GB0313251D0 (en) | 2003-06-10 | 2003-06-10 | Viral inhibitors |
| PCT/BE2003/000117 WO2004005286A2 (en) | 2002-07-03 | 2003-07-03 | Viral inhibitors |
| EP03762361A EP1521754B1 (en) | 2002-07-03 | 2003-07-03 | Viral inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1521754T1 true SI1521754T1 (sl) | 2011-12-30 |
Family
ID=30117086
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200332077T SI1521754T1 (sl) | 2002-07-03 | 2003-07-03 | Virusni inhibitorji |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US7737162B2 (enExample) |
| EP (2) | EP1521754B1 (enExample) |
| JP (2) | JP4907082B2 (enExample) |
| KR (2) | KR101184032B1 (enExample) |
| CN (1) | CN1328279C (enExample) |
| AT (1) | ATE522528T1 (enExample) |
| AU (2) | AU2003243846B9 (enExample) |
| BR (2) | BR122018077110B1 (enExample) |
| CA (1) | CA2491243C (enExample) |
| CY (1) | CY1112042T1 (enExample) |
| DK (1) | DK1521754T3 (enExample) |
| EA (1) | EA013562B1 (enExample) |
| ES (2) | ES2525483T3 (enExample) |
| GB (1) | GB0215293D0 (enExample) |
| IL (1) | IL166055A (enExample) |
| MX (1) | MXPA04012965A (enExample) |
| NO (1) | NO330766B1 (enExample) |
| NZ (1) | NZ537473A (enExample) |
| PT (2) | PT2332938E (enExample) |
| SI (1) | SI1521754T1 (enExample) |
| WO (1) | WO2004005286A2 (enExample) |
Families Citing this family (56)
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| EP2335700A1 (en) | 2001-07-25 | 2011-06-22 | Boehringer Ingelheim (Canada) Ltd. | Hepatitis C virus polymerase inhibitors with a heterobicylic structure |
| GB0215293D0 (en) | 2002-07-03 | 2002-08-14 | Rega Foundation | Viral inhibitors |
| US7098231B2 (en) | 2003-01-22 | 2006-08-29 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
| US7223785B2 (en) | 2003-01-22 | 2007-05-29 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
| BRPI0413234A (pt) | 2003-08-01 | 2006-10-03 | Genelabs Tech Inc | derivados de imidazola bicìclica contra flaviviridae |
| DK2161273T3 (en) * | 2003-12-22 | 2015-07-20 | Leuven K U Res & Dev | Imidazo [4,5-C] pyridine compounds and methods for antiviral therapy |
| CN1902198A (zh) * | 2003-12-22 | 2007-01-24 | 鲁汶天主教大学研究开发部 | 咪唑并[4,5－c]吡啶化合物和抗病毒治疗的方法 |
| CN1922174A (zh) | 2004-02-20 | 2007-02-28 | 贝林格尔·英格海姆国际有限公司 | 病毒聚合酶抑制剂 |
| CN101027303A (zh) * | 2004-07-27 | 2007-08-29 | 吉里德科学公司 | 咪唑并[4，5－d]嘧啶类、其应用和制备方法 |
| PT1841765E (pt) * | 2004-12-21 | 2009-05-14 | Gilead Sciences Inc | Anticorpos para mcp-1 humano |
| US7763715B2 (en) | 2005-04-22 | 2010-07-27 | The Procter & Gamble Company | Extracting biopolymers from a biomass using ionic liquids |
| AP2007004244A0 (en) | 2005-05-10 | 2007-12-31 | Intermune Inc | Method of modulating stress-activated protein kinase system |
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| UY31685A (es) * | 2008-03-04 | 2009-11-10 | Smithkline Beecham Corp | Compuestos antivirales, composiciones y metodos para usarlos |
| GB0809314D0 (en) * | 2008-05-22 | 2008-07-02 | Summit Corp Plc | Compounds for treating muscular dystrophy |
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| US20100204265A1 (en) * | 2009-02-09 | 2010-08-12 | Genelabs Technologies, Inc. | Certain Nitrogen Containing Bicyclic Chemical Entities for Treating Viral Infections |
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| AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
| RU2692485C2 (ru) | 2014-04-02 | 2019-06-25 | Интермьюн, Инк. | Противофиброзные пиридиноны |
| WO2016106050A1 (en) | 2014-12-26 | 2016-06-30 | Emory University | N4-hydroxycytidine and derivatives and anti-viral uses related thereto |
| JOP20160086B1 (ar) | 2015-05-08 | 2021-08-17 | 2 Katholieke Univ Leuven Ku Leuven Research And Development | مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| JO3633B1 (ar) | 2015-09-16 | 2020-08-27 | Katholieke Univ Leuven Ku Leuven Research & Development | مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| JOP20160198B1 (ar) | 2015-09-16 | 2022-03-14 | Janssen Pharmaceuticals Inc | مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
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| HRP20210847T1 (hr) | 2016-03-31 | 2021-07-23 | Janssen Pharmaceuticals, Inc. | Supstituirani derivati indola kao inhibitori replikacije denga virusa |
| EA201892200A1 (ru) | 2016-04-01 | 2019-03-29 | Янссен Фармасьютикалз, Инк. | Замещенные производные соединений индола в качестве ингибиторов репликации вирусов денге |
| JOP20170069B1 (ar) | 2016-04-01 | 2021-08-17 | 1 Janssen Pharmaceuticals Inc | مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
| WO2017168333A1 (en) * | 2016-04-02 | 2017-10-05 | Shilpa Medicare Limited | Amifampridine dihydrochloride |
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| CN109562107A (zh) | 2016-05-10 | 2019-04-02 | C4医药公司 | 用于靶蛋白降解的杂环降解决定子体 |
| CN109562113A (zh) | 2016-05-10 | 2019-04-02 | C4医药公司 | 用于靶蛋白降解的螺环降解决定子体 |
| CN121974842A (zh) | 2016-05-10 | 2026-05-05 | C4医药公司 | 用于靶蛋白降解的胺连接的c3-戊二酰亚胺降解决定子体 |
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| CA3060583C (en) | 2017-05-22 | 2024-06-04 | Janssen Pharmaceuticals, Inc. | Substituted indoline derivatives as dengue viral replication inhibitors |
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| US12509455B2 (en) | 2018-11-07 | 2025-12-30 | Dana-Farber Cancer Institute, Inc. | Imidazopyridine derivatives and aza-imidazopyridine derivatives as Janus kinase 2 inhibitors and uses thereof |
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| CA3156828A1 (en) | 2019-10-03 | 2021-04-08 | Dana-Farber Cancer Institute, Inc. | Tricyclic kinase inhibitors and uses thereof |
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| US12577242B2 (en) | 2020-02-24 | 2026-03-17 | Katholieke Universiteit Leuven | Pyrrolopyridine and imidazopyridine antiviral compounds |
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-
2002
- 2002-07-03 GB GBGB0215293.2A patent/GB0215293D0/en not_active Ceased
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2003
- 2003-07-03 WO PCT/BE2003/000117 patent/WO2004005286A2/en not_active Ceased
- 2003-07-03 PT PT101823086T patent/PT2332938E/pt unknown
- 2003-07-03 KR KR1020047021644A patent/KR101184032B1/ko not_active Expired - Fee Related
- 2003-07-03 PT PT03762361T patent/PT1521754E/pt unknown
- 2003-07-03 EP EP03762361A patent/EP1521754B1/en not_active Expired - Lifetime
- 2003-07-03 MX MXPA04012965A patent/MXPA04012965A/es active IP Right Grant
- 2003-07-03 SI SI200332077T patent/SI1521754T1/sl unknown
- 2003-07-03 CN CNB038201429A patent/CN1328279C/zh not_active Expired - Fee Related
- 2003-07-03 ES ES10182308.6T patent/ES2525483T3/es not_active Expired - Lifetime
- 2003-07-03 JP JP2004518295A patent/JP4907082B2/ja not_active Expired - Fee Related
- 2003-07-03 ES ES03762361T patent/ES2372277T3/es not_active Expired - Lifetime
- 2003-07-03 EA EA200500150A patent/EA013562B1/ru not_active IP Right Cessation
- 2003-07-03 BR BR122018077110-0A patent/BR122018077110B1/pt not_active IP Right Cessation
- 2003-07-03 AT AT03762361T patent/ATE522528T1/de active
- 2003-07-03 AU AU2003243846A patent/AU2003243846B9/en not_active Ceased
- 2003-07-03 CA CA2491243A patent/CA2491243C/en not_active Expired - Fee Related
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- 2003-07-03 KR KR1020117001338A patent/KR101131591B1/ko not_active Expired - Fee Related
- 2003-07-03 NZ NZ537473A patent/NZ537473A/en not_active IP Right Cessation
- 2003-07-03 BR BRPI0312547A patent/BRPI0312547B8/pt not_active IP Right Cessation
- 2003-07-03 US US10/519,756 patent/US7737162B2/en active Active
- 2003-07-03 EP EP10182308.6A patent/EP2332938B1/en not_active Expired - Lifetime
- 2003-07-03 DK DK03762361.8T patent/DK1521754T3/da active
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- 2009-05-19 US US12/468,667 patent/US8779141B2/en not_active Expired - Fee Related
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2011
- 2011-11-11 CY CY20111101084T patent/CY1112042T1/el unknown
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