JP4845379B2 - サイクリン依存性キナーゼインヒビターとしてのイミダゾピリジン - Google Patents

サイクリン依存性キナーゼインヒビターとしてのイミダゾピリジン Download PDF

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Publication number
JP4845379B2
JP4845379B2 JP2004538237A JP2004538237A JP4845379B2 JP 4845379 B2 JP4845379 B2 JP 4845379B2 JP 2004538237 A JP2004538237 A JP 2004538237A JP 2004538237 A JP2004538237 A JP 2004538237A JP 4845379 B2 JP4845379 B2 JP 4845379B2
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JP
Japan
Prior art keywords
group
alkyl
aryl
cycloalkyl
moieties
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Expired - Fee Related
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JP2004538237A
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English (en)
Japanese (ja)
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JP2006507254A5 (cg-RX-API-DMAC7.html
JP2006507254A (ja
Inventor
マイケル ピー． ドワイヤー，
ティモシー ジェイ． グジ，
カミル パルチ，
ロナルド ジェイ． ドール，
カルティック エム． キールティカー，
ヴィヨール エム． ギリジャバルラブハン，
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Merck Sharp and Dohme LLC
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Schering Corp
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Publication of JP2006507254A5 publication Critical patent/JP2006507254A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2004538237A 2002-09-19 2003-09-17 サイクリン依存性キナーゼインヒビターとしてのイミダゾピリジン Expired - Fee Related JP4845379B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41206302P 2002-09-19 2002-09-19
US60/412,063 2002-09-19
PCT/US2003/029498 WO2004026867A2 (en) 2002-09-19 2003-09-17 Imidazopyridines as cyclin dependent kinase inhibitors

Publications (3)

Publication Number Publication Date
JP2006507254A JP2006507254A (ja) 2006-03-02
JP2006507254A5 JP2006507254A5 (cg-RX-API-DMAC7.html) 2006-10-05
JP4845379B2 true JP4845379B2 (ja) 2011-12-28

Family

ID=32030794

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004538237A Expired - Fee Related JP4845379B2 (ja) 2002-09-19 2003-09-17 サイクリン依存性キナーゼインヒビターとしてのイミダゾピリジン

Country Status (18)

Country Link
US (2) US6992080B2 (cg-RX-API-DMAC7.html)
EP (1) EP1539756B1 (cg-RX-API-DMAC7.html)
JP (1) JP4845379B2 (cg-RX-API-DMAC7.html)
KR (1) KR20050052500A (cg-RX-API-DMAC7.html)
CN (1) CN100549011C (cg-RX-API-DMAC7.html)
AR (1) AR041291A1 (cg-RX-API-DMAC7.html)
AT (1) ATE378336T1 (cg-RX-API-DMAC7.html)
AU (1) AU2003295332B2 (cg-RX-API-DMAC7.html)
CA (1) CA2499639C (cg-RX-API-DMAC7.html)
DE (1) DE60317529T2 (cg-RX-API-DMAC7.html)
ES (1) ES2293068T3 (cg-RX-API-DMAC7.html)
IL (1) IL167433A (cg-RX-API-DMAC7.html)
MX (1) MXPA05003058A (cg-RX-API-DMAC7.html)
MY (1) MY133311A (cg-RX-API-DMAC7.html)
NZ (1) NZ538566A (cg-RX-API-DMAC7.html)
TW (1) TWI351405B (cg-RX-API-DMAC7.html)
WO (1) WO2004026867A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200502278B (cg-RX-API-DMAC7.html)

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Also Published As

Publication number Publication date
WO2004026867A2 (en) 2004-04-01
ES2293068T3 (es) 2008-03-16
US20060030555A1 (en) 2006-02-09
HK1071757A1 (en) 2005-07-29
MXPA05003058A (es) 2005-05-27
CA2499639A1 (en) 2004-04-01
AU2003295332A1 (en) 2004-04-08
EP1539756B1 (en) 2007-11-14
MY133311A (en) 2007-11-30
US6992080B2 (en) 2006-01-31
AR041291A1 (es) 2005-05-11
US20040097517A1 (en) 2004-05-20
JP2006507254A (ja) 2006-03-02
AU2003295332B2 (en) 2007-01-18
CN1703414A (zh) 2005-11-30
EP1539756A2 (en) 2005-06-15
DE60317529D1 (de) 2007-12-27
CN100549011C (zh) 2009-10-14
IL167433A (en) 2011-03-31
ATE378336T1 (de) 2007-11-15
WO2004026867A3 (en) 2004-08-05
CA2499639C (en) 2011-11-08
NZ538566A (en) 2008-02-29
DE60317529T2 (de) 2008-09-25
TWI351405B (en) 2011-11-01
KR20050052500A (ko) 2005-06-02
ZA200502278B (en) 2006-05-31
US7452902B2 (en) 2008-11-18
TW200407322A (en) 2004-05-16

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