JP4716641B2 - グルカゴン様ペプチド−１類似体 - Google Patents

グルカゴン様ペプチド−１類似体 Download PDF

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Publication number
JP4716641B2
JP4716641B2 JP2002504286A JP2002504286A JP4716641B2 JP 4716641 B2 JP4716641 B2 JP 4716641B2 JP 2002504286 A JP2002504286 A JP 2002504286A JP 2002504286 A JP2002504286 A JP 2002504286A JP 4716641 B2 JP4716641 B2 JP 4716641B2
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glp
seq
glu
twenty
xaa
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JP2004501162A5 (cg-RX-API-DMAC7.html
JP2004501162A (ja
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ヴォルフガング・グレースナー
ローン・リー・ミリキャン
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イーライ リリー アンド カンパニー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2002504286A 2000-06-16 2001-06-01 グルカゴン様ペプチド−１類似体 Expired - Fee Related JP4716641B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US21217100P 2000-06-16 2000-06-16
US60/212,171 2000-06-16
US24034900P 2000-10-13 2000-10-13
US60/240,349 2000-10-13
PCT/US2001/016474 WO2001098331A2 (en) 2000-06-16 2001-06-01 Glucagon-like peptide-1 analogs

Publications (3)

Publication Number Publication Date
JP2004501162A JP2004501162A (ja) 2004-01-15
JP2004501162A5 JP2004501162A5 (cg-RX-API-DMAC7.html) 2008-07-24
JP4716641B2 true JP4716641B2 (ja) 2011-07-06

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JP2002504286A Expired - Fee Related JP4716641B2 (ja) 2000-06-16 2001-06-01 グルカゴン様ペプチド−１類似体

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US (2) US7084243B2 (cg-RX-API-DMAC7.html)
EP (2) EP1695983B1 (cg-RX-API-DMAC7.html)
JP (1) JP4716641B2 (cg-RX-API-DMAC7.html)
KR (1) KR100847615B1 (cg-RX-API-DMAC7.html)
CN (1) CN100469791C (cg-RX-API-DMAC7.html)
AR (1) AR031701A1 (cg-RX-API-DMAC7.html)
AT (2) ATE424413T1 (cg-RX-API-DMAC7.html)
AU (2) AU6479101A (cg-RX-API-DMAC7.html)
BR (1) BR0111562A (cg-RX-API-DMAC7.html)
CA (1) CA2412004C (cg-RX-API-DMAC7.html)
CY (2) CY1105917T1 (cg-RX-API-DMAC7.html)
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DE (2) DE60137876D1 (cg-RX-API-DMAC7.html)
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DZ (1) DZ3388A1 (cg-RX-API-DMAC7.html)
EA (1) EA008837B1 (cg-RX-API-DMAC7.html)
EG (1) EG24755A (cg-RX-API-DMAC7.html)
ES (2) ES2275685T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20020996B1 (cg-RX-API-DMAC7.html)
HU (2) HU229208B1 (cg-RX-API-DMAC7.html)
IL (2) IL153453A0 (cg-RX-API-DMAC7.html)
MX (1) MXPA02012203A (cg-RX-API-DMAC7.html)
MY (1) MY137350A (cg-RX-API-DMAC7.html)
NO (1) NO330686B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ522330A (cg-RX-API-DMAC7.html)
PE (1) PE20011363A1 (cg-RX-API-DMAC7.html)
PL (1) PL206302B1 (cg-RX-API-DMAC7.html)
PT (2) PT1695983E (cg-RX-API-DMAC7.html)
SI (1) SI1695983T1 (cg-RX-API-DMAC7.html)
SK (1) SK287757B6 (cg-RX-API-DMAC7.html)
TW (1) TWI321134B (cg-RX-API-DMAC7.html)
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Families Citing this family (162)

* Cited by examiner, † Cited by third party
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