JP4511550B2 - オルメサルタンメドキソミルの調製法 - Google Patents

オルメサルタンメドキソミルの調製法 Download PDF

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Publication number
JP4511550B2
JP4511550B2 JP2006538570A JP2006538570A JP4511550B2 JP 4511550 B2 JP4511550 B2 JP 4511550B2 JP 2006538570 A JP2006538570 A JP 2006538570A JP 2006538570 A JP2006538570 A JP 2006538570A JP 4511550 B2 JP4511550 B2 JP 4511550B2
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Japan
Prior art keywords
olmesartan medoxomil
acid
water
solution
process according
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JP2006538570A
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Japanese (ja)
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JP2007509992A5 (enExample
JP2007509992A (ja
Inventor
ヘドバティ，リアヒ
ピラルスキー，ギデオン
Original Assignee
テバ ファーマシューティカル インダストリーズ リミティド
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Publication of JP2007509992A publication Critical patent/JP2007509992A/ja
Publication of JP2007509992A5 publication Critical patent/JP2007509992A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2006538570A 2004-09-02 2005-09-02 オルメサルタンメドキソミルの調製法 Expired - Fee Related JP4511550B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60643704P 2004-09-02 2004-09-02
PCT/US2005/031481 WO2006029056A1 (en) 2004-09-02 2005-09-02 Preparation of olmesartan medoxomil

Publications (3)

Publication Number Publication Date
JP2007509992A JP2007509992A (ja) 2007-04-19
JP2007509992A5 JP2007509992A5 (enExample) 2010-04-22
JP4511550B2 true JP4511550B2 (ja) 2010-07-28

Family

ID=35462159

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006538570A Expired - Fee Related JP4511550B2 (ja) 2004-09-02 2005-09-02 オルメサルタンメドキソミルの調製法

Country Status (7)

Country Link
US (1) US7528258B2 (enExample)
EP (1) EP1706401A1 (enExample)
JP (1) JP4511550B2 (enExample)
CN (2) CN1993355A (enExample)
CA (1) CA2573800A1 (enExample)
IL (1) IL181549A0 (enExample)
WO (1) WO2006029056A1 (enExample)

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US20060281800A1 (en) * 2005-04-12 2006-12-14 Glenmark Pharmaceuticals Limited Polymorphic form of olmesartan and process for its preparation
EA014026B1 (ru) * 2005-07-29 2010-08-30 Крка, Товарна Здравил, Д.Д., Ново Место Способ получения олмесартан медоксомила
EP1816131A1 (en) * 2006-02-06 2007-08-08 KRKA, tovarna zdravil, d.d., Novo mesto Process for the preparation of olmesartan medoxomil
EP2022790A1 (en) * 2007-08-08 2009-02-11 LEK Pharmaceuticals D.D. A process for the preparation or purification of olmesartan medoxomil
CA2707365A1 (en) 2007-08-08 2009-02-12 Lek Pharmaceuticals D.D. A process for the preparation of olmesartan medoxomil
KR101630885B1 (ko) 2008-06-09 2016-06-15 다이이찌 산쿄 가부시키가이샤 1-비페닐메틸이미다졸 화합물의 제조 방법
ES2527686T3 (es) * 2009-04-28 2015-01-28 Daiichi Sankyo Company, Limited Procedimiento de producción de olmesartán medoxomil
CA2760031C (en) 2009-04-28 2015-03-10 Daiichi Sankyo Company, Limited Acetone solvate crystals of trityl olmesartan medoxomil
WO2010134052A1 (en) 2009-05-20 2010-11-25 Ranbaxy Laboratories Limited Process for the preparation of olmesartan medoxomil
WO2011014611A2 (en) * 2009-07-30 2011-02-03 Dr. Reddy's Laboratories Ltd. Preparation of olmesartan medoxomil
CA2769704A1 (en) * 2009-07-31 2011-02-03 Ranbaxy Laboratories Limited Polymorphic form of olmesartan medoxomil
EP2409710A1 (en) 2010-06-29 2012-01-25 NanotecMARIN GmbH Injectable material and material to be used as drug or food supplement for prophylaxis or treatment of osteoporosis
EP2409682A1 (en) 2010-07-19 2012-01-25 Werner E. G. MÜLLER Hydroxyapatite-binding nano- and microparticles for caries prophylaxis and reduction of dental hypersensitivity
KR101266224B1 (ko) 2010-09-02 2013-05-21 일동제약주식회사 트리틸 올메사르탄 메독소밀의 개선된 제조방법
CZ2010785A3 (cs) 2010-10-29 2012-05-16 Zentiva, K.S. Zpusob výroby olmesartanu medoxomilu
AR083523A1 (es) 2010-10-29 2013-03-06 Interquim Sa Procedimiento de obtencion del olmesartan medoxomilo
EP2489346A1 (en) 2011-01-26 2012-08-22 NanotecMARIN GmbH Food supplement and injectable material for prophylaxis and therapy of osteoporosis and other bone diseases
EP2739619B1 (en) 2011-08-05 2015-09-16 Lupin Limited Process for the preparation of olmesartan medoxomil
CN102558161B (zh) * 2011-12-07 2016-07-06 浙江华海药业股份有限公司 一种采用丙酮与水混合液精制奥美沙坦酯的工艺
CN102584804B (zh) * 2011-12-13 2016-05-18 浙江华海药业股份有限公司 一种三苯甲基奥美沙坦酯脱保护基制备奥美沙坦酯的工艺
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WO2014036686A1 (zh) * 2012-09-04 2014-03-13 上海迪赛诺化学制药有限公司 奥美沙坦酯的制备方法
CN108658954A (zh) * 2018-06-12 2018-10-16 广州小桔生物科技有限公司 一种高纯度奥美沙坦酯的精制方法
CN109761966A (zh) * 2019-01-30 2019-05-17 浙江省食品药品检验研究院 一种奥美沙坦酯晶体及其制备方法
CN111170946B (zh) * 2020-03-16 2022-02-11 浙江华洲药业有限公司 一种奥美沙坦中间体的合成方法

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JPH08325248A (ja) 1995-05-26 1996-12-10 Chugoku Kayaku Kk テトラゾール類の新規な合成試薬及びそれを用いたテトラゾール類の製造方法
US5994348A (en) 1995-06-07 1999-11-30 Sanofi Pharmaceutical compositions containing irbesartan
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JP4185182B2 (ja) 1998-04-08 2008-11-26 第一三共株式会社 イミダゾール誘導体の製造方法
JP4260241B2 (ja) 1998-04-21 2009-04-30 第一三共株式会社 イミダゾール誘導体の製造法
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DK1535901T3 (da) 2002-06-12 2008-04-07 Sumitomo Chemical Co Fremgangsmåde til fremstilling af 4' -brommethyl-2-cyanobiphenyl
CN1271068C (zh) 2003-03-25 2006-08-23 上海医药工业研究院 一种奥美沙坦酯的制备方法
ITMI20032338A1 (it) * 2003-11-28 2005-05-29 Dinamite Dipharma S P A In Forma A Bbreviata Diph Composti feniltetrazolici.

Also Published As

Publication number Publication date
IL181549A0 (en) 2007-07-04
US20060069141A1 (en) 2006-03-30
CN1993355A (zh) 2007-07-04
EP1706401A1 (en) 2006-10-04
CN1976926A (zh) 2007-06-06
CA2573800A1 (en) 2006-03-16
JP2007509992A (ja) 2007-04-19
WO2006029056A1 (en) 2006-03-16
US7528258B2 (en) 2009-05-05

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