JP3759621B2 - アスコルビン酸、２―ケト―ｌ―グロン酸及び２―ケト―ｌ―グロン酸のエステルの製造のための酵素的方法 - Google Patents

アスコルビン酸、２―ケト―ｌ―グロン酸及び２―ケト―ｌ―グロン酸のエステルの製造のための酵素的方法 Download PDF

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JP3759621B2
JP3759621B2 JP54120797A JP54120797A JP3759621B2 JP 3759621 B2 JP3759621 B2 JP 3759621B2 JP 54120797 A JP54120797 A JP 54120797A JP 54120797 A JP54120797 A JP 54120797A JP 3759621 B2 JP3759621 B2 JP 3759621B2
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klg
keto
ester
gulonic acid
acid
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JP2001505042A (ja
JP2001505042A5 (zh
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クラーク ハブス，ジョン
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Eastman Chemical Co
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Eastman Chemical Co
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/58—Aldonic, ketoaldonic or saccharic acids
    • C12P7/60—2-Ketogulonic acid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus
    • Y10S435/836—Bacillus licheniformis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/847—Erwinia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/913—Aspergillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/921—Candida
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/933—Penicillium

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
JP54120797A 1996-05-17 1997-05-16 アスコルビン酸、２―ケト―ｌ―グロン酸及び２―ケト―ｌ―グロン酸のエステルの製造のための酵素的方法 Expired - Fee Related JP3759621B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US1787996P 1996-05-17 1996-05-17
US08/845,295 1997-04-25
US60/017,879 1997-04-25
US08/845,295 US5817490A (en) 1996-05-17 1997-04-25 Enzymatic process for the manufacture of ascorbic acid 2-keto-L-gulonic acid and esters of 2-keto-L-gulonic acid
PCT/US1997/008668 WO1997043433A1 (en) 1996-05-17 1997-05-16 Enzymatic process for the manufacture of ascorbic acid, 2-keto-l-gulonic acid and esters of 2-keto-l-gulonic acid

Publications (3)

Publication Number Publication Date
JP2001505042A JP2001505042A (ja) 2001-04-17
JP2001505042A5 JP2001505042A5 (zh) 2005-01-13
JP3759621B2 true JP3759621B2 (ja) 2006-03-29

Family

ID=26690448

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54120797A Expired - Fee Related JP3759621B2 (ja) 1996-05-17 1997-05-16 アスコルビン酸、２―ケト―ｌ―グロン酸及び２―ケト―ｌ―グロン酸のエステルの製造のための酵素的方法

Country Status (10)

Country Link
US (4) US5817490A (zh)
EP (1) EP0938582B1 (zh)
JP (1) JP3759621B2 (zh)
CN (3) CN1181206C (zh)
AT (1) ATE238429T1 (zh)
AU (1) AU3075697A (zh)
BR (1) BR9709099A (zh)
DE (1) DE69721292T2 (zh)
MY (1) MY134224A (zh)
WO (1) WO1997043433A1 (zh)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817490A (en) * 1996-05-17 1998-10-06 Eastman Chemical Company Enzymatic process for the manufacture of ascorbic acid 2-keto-L-gulonic acid and esters of 2-keto-L-gulonic acid
EP1026257B1 (en) * 1999-01-18 2006-04-12 DSM IP Assets B.V. Manufacture of L-ascorbic acid and D-erythorbic acid
CA2296020A1 (en) * 1999-01-18 2000-07-18 F. Hoffmann-La Roche Ag Manufacture of l-ascorbic acid and d-erythorbic acid
DE19938980A1 (de) * 1999-08-19 2001-02-22 Basf Ag Verfahren zur Herstellung von 2-Keto-L-gulonsäureestern
US6720168B2 (en) 2000-08-04 2004-04-13 Genencor International, Inc. 2,5-DKG permeases
BR0113036A (pt) * 2000-08-04 2006-02-21 Microgenomics Inc 2,5-dkg permeases
AU781277B2 (en) * 2000-08-23 2005-05-12 Dsm Ip Assets B.V. Microbial production of L-ascorbic acid and D-erythorbic acid
EP1182262A1 (en) * 2000-08-23 2002-02-27 Roche Vitamins AG Microbial production of l-ascorbic acid and d-erythorbic acid
US6642035B2 (en) * 2001-01-26 2003-11-04 The Scripps Research Institute Synthesis of B-keto esters
US20070298474A1 (en) * 2001-08-03 2007-12-27 Manoj Kumar Enhanced 2-Keto-L-Gulonic acid production
US7229811B2 (en) * 2001-08-03 2007-06-12 Genencor International, Inc. 2,5-diketo-D-gluconic acid (2,5-DKG) permeases
US7465563B2 (en) 2001-11-09 2008-12-16 Dsm Ip Assets B.V. Enzymatic process for the manufacture of L-ascorbic acid and D-erythorbic acid
ATE322499T1 (de) 2002-11-11 2006-04-15 Verfahren zur herstellung von 2-keto-l-gulonsäure-c-4 c-10 /sb -alkylestern
BRPI0608223A2 (pt) * 2005-02-11 2009-11-24 Dsm Ip Assets Bv gene sms 05
AT502990A1 (de) * 2005-12-27 2007-07-15 Dsm Fine Chem Austria Gmbh Neues polypeptid mit esteraseaktivität, und rekombinante esterase sowie deren verwendung
CA2646593C (en) * 2006-03-20 2015-12-08 Duramed Pharmaceuticals, Inc. Flexible, compressed intravaginal rings, methods of making and using the same, and apparatus for making the same
JP5438259B2 (ja) * 2006-04-13 2014-03-12 Ｂｉｏ−ｅｎｅｒｇｙ株式会社 カンジダ・アンタークティカ由来リパーゼｂを細胞表層に提示する酵母
US8759044B2 (en) 2011-03-23 2014-06-24 Butamax Advanced Biofuels Llc In situ expression of lipase for enzymatic production of alcohol esters during fermentation
US8765425B2 (en) 2011-03-23 2014-07-01 Butamax Advanced Biofuels Llc In situ expression of lipase for enzymatic production of alcohol esters during fermentation
WO2012130961A1 (en) * 2011-03-30 2012-10-04 Novozymes A/S Esterification process
CN103344719B (zh) * 2013-06-27 2015-04-15 东北制药集团股份有限公司 一种可同时检测古龙酸、古龙酸甲酯、甲醇和乙醇的高效液相方法
CN111377543A (zh) * 2018-12-27 2020-07-07 南京百斯杰生物工程有限公司 脂肪酶在降低黄水酸度中的应用
KR102357426B1 (ko) * 2019-12-10 2022-01-28 건국대학교 산학협력단 신규 에스터 가수분해효소를 이용한 베타 아미노산의 효소적 생산방법

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES135896A1 (es) * 1933-10-25 1934-12-16 Hoffmann La Roche PROCEDIMIENTO PARA LA FABRICACIoN DEL áCIDO 2-CETO-1-GULoNICO
GB466548A (en) * 1935-11-26 1937-05-31 Tadeus Reichstein Process for the manufacture of laevo-ascorbic acid (vitamin-c)
US4760025A (en) * 1984-05-29 1988-07-26 Genencor, Inc. Modified enzymes and methods for making same
US4595659A (en) * 1983-10-20 1986-06-17 Kraft, Inc. Fermentation production of ascorbic acid from L-galactonic substrate
US5008193A (en) * 1984-06-14 1991-04-16 Genentech, Inc. Ascorbic acid intermediates and process enzymes
US5001059A (en) * 1985-07-01 1991-03-19 Bio-Technical Resources, Inc. L-ascorbic acid production in microorganisms
CN86105960A (zh) * 1985-08-09 1987-05-13 鲁布里佐尔公司 在基本无水条件下从2-酮-l-古洛糖酸制备l-抗坏血酸
US5079153A (en) * 1989-06-03 1992-01-07 Mitsubishi Rayon Co., Ltd. Process for the preparation of organic esters of ascorbic acid or erythorbic acid using ester hydralases in organic solvents containing 100-10,000 ppm of water
JPH04141093A (ja) * 1990-10-03 1992-05-14 Mitsubishi Rayon Co Ltd 有機酸エステルの製造法
JPH04335893A (ja) * 1991-05-07 1992-11-24 Mitsubishi Rayon Co Ltd 固定化酵素を用いるエステル合成方法
EP0514694B1 (en) * 1991-05-18 1997-07-23 Mitsubishi Rayon Co., Ltd Process for producing ascorbic or erythorbic acid esters
JPH061783A (ja) * 1992-06-17 1994-01-11 Mitsubishi Rayon Co Ltd 有機酸エステルの製造法
US5817490A (en) * 1996-05-17 1998-10-06 Eastman Chemical Company Enzymatic process for the manufacture of ascorbic acid 2-keto-L-gulonic acid and esters of 2-keto-L-gulonic acid

Also Published As

Publication number Publication date
CN1182250C (zh) 2004-12-29
EP0938582A1 (en) 1999-09-01
US6136575A (en) 2000-10-24
AU3075697A (en) 1997-12-05
US6022719A (en) 2000-02-08
EP0938582B1 (en) 2003-04-23
DE69721292D1 (de) 2003-05-28
CN1113100C (zh) 2003-07-02
WO1997043433A1 (en) 1997-11-20
CN1412316A (zh) 2003-04-23
BR9709099A (pt) 1999-08-03
CN1225686A (zh) 1999-08-11
ATE238429T1 (de) 2003-05-15
CN1181206C (zh) 2004-12-22
DE69721292T2 (de) 2003-11-13
JP2001505042A (ja) 2001-04-17
US5817490A (en) 1998-10-06
US6271006B1 (en) 2001-08-07
MY134224A (en) 2007-11-30
CN1412315A (zh) 2003-04-23

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