JP2535080B2 - マクロライド化合物 - Google Patents

マクロライド化合物

Info

Publication number
JP2535080B2
JP2535080B2 JP1328100A JP32810089A JP2535080B2 JP 2535080 B2 JP2535080 B2 JP 2535080B2 JP 1328100 A JP1328100 A JP 1328100A JP 32810089 A JP32810089 A JP 32810089A JP 2535080 B2 JP2535080 B2 JP 2535080B2
Authority
JP
Japan
Prior art keywords
compound
nrrl
acid
culture
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP1328100A
Other languages
English (en)
Japanese (ja)
Other versions
JPH02223589A (ja
Inventor
ラヴァーン・ドゥエイン・ボエック
ハング・チョ
トム・エドワード・イートン
オティス・ウェブスター・ゴッドフリ，ジュニア
カール・ハインツ・マイケル
ウォールター・ミツオ・ナカツカサ
レイモンド・チェ‐フォン・ヤオ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of JPH02223589A publication Critical patent/JPH02223589A/ja
Application granted granted Critical
Publication of JP2535080B2 publication Critical patent/JP2535080B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Agronomy & Crop Science (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyrane Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyrrole Compounds (AREA)
JP1328100A 1988-12-19 1989-12-18 マクロライド化合物 Expired - Lifetime JP2535080B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US28659188A 1988-12-19 1988-12-19
US286591 1988-12-19
US42944189A 1989-10-30 1989-10-30
US429441 1989-10-30

Publications (2)

Publication Number Publication Date
JPH02223589A JPH02223589A (ja) 1990-09-05
JP2535080B2 true JP2535080B2 (ja) 1996-09-18

Family

ID=26963932

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1328100A Expired - Lifetime JP2535080B2 (ja) 1988-12-19 1989-12-18 マクロライド化合物

Country Status (32)

Country Link
US (2) US5496931A (Direct)
EP (1) EP0375316B1 (Direct)
JP (1) JP2535080B2 (Direct)
KR (1) KR0143566B1 (Direct)
CN (1) CN1035391C (Direct)
AT (1) ATE116325T1 (Direct)
AU (1) AU624458B2 (Direct)
BG (1) BG60520B1 (Direct)
BR (1) BR8906547A (Direct)
CA (1) CA2005784C (Direct)
CZ (1) CZ285992B6 (Direct)
DE (2) DE68920301T2 (Direct)
DK (1) DK174489B1 (Direct)
DZ (1) DZ1375A1 (Direct)
EG (1) EG19191A (Direct)
ES (1) ES2065398T3 (Direct)
FI (2) FI95601C (Direct)
GR (1) GR3015598T3 (Direct)
HU (1) HU208998B (Direct)
IE (1) IE65919B1 (Direct)
IL (1) IL92743A (Direct)
IN (1) IN169756B (Direct)
MA (1) MA21697A1 (Direct)
MY (1) MY111148A (Direct)
NL (1) NL350009I2 (Direct)
NO (1) NO176914C (Direct)
NZ (1) NZ231831A (Direct)
OA (1) OA09249A (Direct)
PE (1) PE5591A1 (Direct)
PL (1) PL161476B1 (Direct)
PT (1) PT92607B (Direct)
YU (1) YU47099B (Direct)

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US5202242A (en) * 1991-11-08 1993-04-13 Dowelanco A83543 compounds and processes for production thereof
US5591606A (en) * 1992-11-06 1997-01-07 Dowelanco Process for the production of A83543 compounds with Saccharopolyspora spinosa
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AU4689189A (en) 1990-06-21
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CN1043742A (zh) 1990-07-11
NZ231831A (en) 1994-10-26
BG90678A (bg) 1993-12-24
BG60520B1 (bg) 1995-07-28
CN1035391C (zh) 1997-07-09
KR900009681A (ko) 1990-07-05
DZ1375A1 (fr) 2004-09-13
IL92743A (en) 1994-10-21
DE122007000053I2 (de) 2009-09-17
DK642089D0 (da) 1989-12-18
NL350009I2 (nl) 2003-08-01
EP0375316B1 (en) 1994-12-28
NO176914C (no) 1995-06-21
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MA21697A1 (fr) 1990-07-01
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MY111148A (en) 1999-09-30
DK642089A (da) 1990-06-20
BR8906547A (pt) 1990-09-04
CZ717089A3 (cs) 1999-08-11
IE894068L (en) 1990-06-19
EG19191A (en) 1994-09-29
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OA09249A (fr) 1992-06-30
HUT52562A (en) 1990-07-28
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US5496931A (en) 1996-03-05
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US5571901A (en) 1996-11-05
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