JP2024114921A5 - - Google Patents

Download PDF

Info

Publication number
JP2024114921A5
JP2024114921A5 JP2024105200A JP2024105200A JP2024114921A5 JP 2024114921 A5 JP2024114921 A5 JP 2024114921A5 JP 2024105200 A JP2024105200 A JP 2024105200A JP 2024105200 A JP2024105200 A JP 2024105200A JP 2024114921 A5 JP2024114921 A5 JP 2024114921A5
Authority
JP
Japan
Prior art keywords
invention described
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024105200A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024114921A (ja
Filing date
Publication date
Priority claimed from JP2021504769A external-priority patent/JP7584401B2/ja
Application filed filed Critical
Publication of JP2024114921A publication Critical patent/JP2024114921A/ja
Publication of JP2024114921A5 publication Critical patent/JP2024114921A5/ja
Pending legal-status Critical Current

Links

JP2024105200A 2018-07-30 2024-06-28 操作されたグリコシルトランスフェラーゼおよびステビオールグリコシドのグルコシル化方法 Pending JP2024114921A (ja)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201862712199P 2018-07-30 2018-07-30
US62/712,199 2018-07-30
US201862712327P 2018-07-31 2018-07-31
US62/712,327 2018-07-31
JP2021504769A JP7584401B2 (ja) 2018-07-30 2019-07-17 操作されたグリコシルトランスフェラーゼおよびステビオールグリコシドのグルコシル化方法
PCT/US2019/042151 WO2020028039A1 (en) 2018-07-30 2019-07-17 Engineered glycosyltransferases and steviol glycoside glucosylation methods

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2021504769A Division JP7584401B2 (ja) 2018-07-30 2019-07-17 操作されたグリコシルトランスフェラーゼおよびステビオールグリコシドのグルコシル化方法

Publications (2)

Publication Number Publication Date
JP2024114921A JP2024114921A (ja) 2024-08-23
JP2024114921A5 true JP2024114921A5 (https=) 2025-04-03

Family

ID=69178045

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2021504769A Active JP7584401B2 (ja) 2018-07-30 2019-07-17 操作されたグリコシルトランスフェラーゼおよびステビオールグリコシドのグルコシル化方法
JP2022113740A Active JP7584474B2 (ja) 2018-07-30 2022-07-15 操作されたグリコシルトランスフェラーゼおよびステビオールグリコシドのグルコシル化方法
JP2022113739A Active JP7584473B2 (ja) 2018-07-30 2022-07-15 操作されたグリコシルトランスフェラーゼおよびステビオールグリコシドのグルコシル化方法
JP2024105200A Pending JP2024114921A (ja) 2018-07-30 2024-06-28 操作されたグリコシルトランスフェラーゼおよびステビオールグリコシドのグルコシル化方法

Family Applications Before (3)

Application Number Title Priority Date Filing Date
JP2021504769A Active JP7584401B2 (ja) 2018-07-30 2019-07-17 操作されたグリコシルトランスフェラーゼおよびステビオールグリコシドのグルコシル化方法
JP2022113740A Active JP7584474B2 (ja) 2018-07-30 2022-07-15 操作されたグリコシルトランスフェラーゼおよびステビオールグリコシドのグルコシル化方法
JP2022113739A Active JP7584473B2 (ja) 2018-07-30 2022-07-15 操作されたグリコシルトランスフェラーゼおよびステビオールグリコシドのグルコシル化方法

Country Status (13)

Country Link
US (3) US11760981B2 (https=)
EP (1) EP3830106A4 (https=)
JP (4) JP7584401B2 (https=)
KR (1) KR20210040408A (https=)
CN (2) CN121538193A (https=)
AU (2) AU2019314181B2 (https=)
BR (1) BR112021001661A8 (https=)
CA (1) CA3108268A1 (https=)
IL (2) IL280302B2 (https=)
MX (1) MX2021001260A (https=)
SG (1) SG11202100470WA (https=)
TW (1) TW202019951A (https=)
WO (1) WO2020028039A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3497222T (pt) 2016-08-12 2022-02-09 Amyris Inc Glicosiltransferase dependente de udp para produção de eficácia elevada de rebaudiosídeos
KR102905512B1 (ko) 2017-02-03 2025-12-29 테이트 앤드 라일 솔루션스 유에스에이 엘엘씨 조작된 글리코실트랜스퍼라제 및 스테비올 글리코시드 글루코실화 방법
IL280302B2 (en) 2018-07-30 2025-09-01 Codexis Inc Engineered glycosyltransferases and methods for glycosylation of steviol glycoside
CN111621482B (zh) * 2020-06-30 2022-04-29 浙江工业大学 一种草铵膦脱氢酶突变体、基因工程菌及一锅法多酶同步定向进化方法
EP4176070A1 (en) 2020-07-03 2023-05-10 c-LEcta GmbH One-pot cell-free glycosylation process
CN112760302B (zh) * 2020-12-23 2022-08-26 中化健康产业发展有限公司 一种能够催化莱鲍迪苷A生成莱鲍迪苷D的糖基转移酶StUGT
US20240368661A1 (en) * 2021-02-17 2024-11-07 Arzeda Corp. Compositions and methods for producing rebaudioside d
WO2022253282A1 (zh) * 2021-06-01 2022-12-08 弈柯莱生物科技(上海)股份有限公司 一种糖基转移酶及其应用
CN115418358B (zh) * 2021-06-01 2024-01-30 弈柯莱生物科技(集团)股份有限公司 一种糖基转移酶及其应用
CN115449514B (zh) * 2021-06-08 2023-09-29 弈柯莱生物科技(上海)股份有限公司 一种β-1,2-糖基转移酶及其应用
CN113462670B (zh) * 2021-08-23 2023-03-24 兴化格林生物制品有限公司 一种糖基转移酶突变体及其催化合成莱鲍迪苷m的方法
CN115725528B (zh) * 2021-08-30 2024-01-12 弈柯莱生物科技(集团)股份有限公司 一种糖基转移酶及其应用
CN116555210B (zh) * 2022-01-30 2025-06-13 弈柯莱生物科技(集团)股份有限公司 糖基转移酶及其在制备莱鲍迪苷e中的应用
CN119256080A (zh) * 2022-05-23 2025-01-03 苏州引航生物科技有限公司 微生物来源的蔗糖合酶及其应用
CA3266431A1 (en) * 2022-09-02 2024-03-07 Arzeda Corp. Compositions and methods for producing rebaudioside m
CN120858181A (zh) 2022-12-05 2025-10-28 泰特和莱尔解决方案美国公司 获得甜菊醇糖苷的方法
WO2025039672A1 (zh) * 2023-08-24 2025-02-27 弈柯莱生物科技(集团)股份有限公司 莱鲍迪苷M的制备方法和β-1,2-葡萄糖基转移酶在其中的应用
KR102840622B1 (ko) * 2024-10-22 2025-08-01 주식회사 삼양사 Udp-글루코실트랜스퍼라제 변이체, udp-글루코실트랜스퍼라제 변이체 융합효소 및 이의 스테비올 배당체 생산 용도

Family Cites Families (186)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58149697A (ja) 1982-02-27 1983-09-06 Dainippon Ink & Chem Inc β−1,3グリコシルステビオシドの製造方法
US5834252A (en) 1995-04-18 1998-11-10 Glaxo Group Limited End-complementary polymerase reaction
US5837458A (en) 1994-02-17 1998-11-17 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US6406855B1 (en) 1994-02-17 2002-06-18 Maxygen, Inc. Methods and compositions for polypeptide engineering
US20060257890A1 (en) 1996-05-20 2006-11-16 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US6395547B1 (en) 1994-02-17 2002-05-28 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US6335160B1 (en) 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
US6165793A (en) 1996-03-25 2000-12-26 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US6117679A (en) 1994-02-17 2000-09-12 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US6309883B1 (en) 1994-02-17 2001-10-30 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US6995017B1 (en) 1994-02-17 2006-02-07 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US5928905A (en) 1995-04-18 1999-07-27 Glaxo Group Limited End-complementary polymerase reaction
WO1995033836A1 (en) 1994-06-03 1995-12-14 Novo Nordisk Biotech, Inc. Phosphonyldipeptides useful in the treatment of cardiovascular diseases
ATE294871T1 (de) 1994-06-30 2005-05-15 Novozymes Biotech Inc Nicht-toxisches, nicht-toxigenes, nicht- pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren
FI104465B (fi) 1995-06-14 2000-02-15 Valio Oy Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö
US6506602B1 (en) 1996-03-25 2003-01-14 Maxygen, Inc. Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
US6096548A (en) 1996-03-25 2000-08-01 Maxygen, Inc. Method for directing evolution of a virus
US6326204B1 (en) 1997-01-17 2001-12-04 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
EP1717322B1 (en) 1997-01-17 2012-07-18 Codexis Mayflower Holdings, LLC Evolution of whole cells and organisms by recursive sequence recombination
US7148054B2 (en) 1997-01-17 2006-12-12 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
US6265201B1 (en) 1997-01-17 2001-07-24 Regents Of The University Of Minnesota DNA molecules and protein displaying improved triazine compound degrading ability
DK1036198T3 (da) 1997-12-08 2013-01-02 California Inst Of Techn Fremgangsmåde til fremstilling af polynukleotid- og polypeptidsekvenser
IL138800A0 (en) 1998-04-02 2001-10-31 Tellus Genetic Resources Inc A method of identifying a plant with a lesion in a gene sequence
NZ507591A (en) 1998-05-01 2002-03-28 Maxygen Inc Optimization of pest resistance genes using DNA shuffling
WO1999065927A2 (en) 1998-06-17 1999-12-23 Maxygen, Inc. Method for producing polynucleotides with desired properties
US6365408B1 (en) 1998-06-19 2002-04-02 Maxygen, Inc. Methods of evolving a polynucleotides by mutagenesis and recombination
WO2000009682A1 (en) 1998-08-12 2000-02-24 Maxygen, Inc. Dna shuffling of monooxygenase genes for production of industrial chemicals
CA2345203A1 (en) 1998-10-07 2000-04-13 Maxygen Inc. Dna shuffling to produce nucleic acids for mycotoxin detoxification
EP1129184A1 (en) 1998-11-10 2001-09-05 Maxygen, Inc. Modified adp-glucose pyrophosphorylase for improvement and optimation of plant phenotypes
JP4221100B2 (ja) 1999-01-13 2009-02-12 エルピーダメモリ株式会社 半導体装置
US6917882B2 (en) 1999-01-19 2005-07-12 Maxygen, Inc. Methods for making character strings, polynucleotides and polypeptides having desired characteristics
US6436675B1 (en) 1999-09-28 2002-08-20 Maxygen, Inc. Use of codon-varied oligonucleotide synthesis for synthetic shuffling
US6368861B1 (en) 1999-01-19 2002-04-09 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US6376246B1 (en) 1999-02-05 2002-04-23 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US7702464B1 (en) 2001-08-21 2010-04-20 Maxygen, Inc. Method and apparatus for codon determining
US7024312B1 (en) 1999-01-19 2006-04-04 Maxygen, Inc. Methods for making character strings, polynucleotides and polypeptides having desired characteristics
US8457903B1 (en) 1999-01-19 2013-06-04 Codexis Mayflower Holdings, Llc Method and/or apparatus for determining codons
EP1130093A1 (en) 1999-01-19 2001-09-05 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US7873477B1 (en) 2001-08-21 2011-01-18 Codexis Mayflower Holdings, Llc Method and system using systematically varied data libraries
US20070065838A1 (en) 1999-01-19 2007-03-22 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US6961664B2 (en) 1999-01-19 2005-11-01 Maxygen Methods of populating data structures for use in evolutionary simulations
JP2003524394A (ja) 1999-02-11 2003-08-19 マキシジェン, インコーポレイテッド ハイスループット質量分析法
CA2362737A1 (en) 1999-03-05 2000-09-08 Maxygen, Inc. Recombination of insertion modified nucleic acids
US6703240B1 (en) 1999-04-13 2004-03-09 Maxygar, Inc. Modified starch metabolism enzymes and encoding genes for improvement and optimization of plant phenotypes
US7430477B2 (en) 1999-10-12 2008-09-30 Maxygen, Inc. Methods of populating data structures for use in evolutionary simulations
US6519065B1 (en) 1999-11-05 2003-02-11 Jds Fitel Inc. Chromatic dispersion compensation device
US6686515B1 (en) 1999-11-23 2004-02-03 Maxygen, Inc. Homologous recombination in plants
IL150291A0 (en) 2000-01-11 2002-12-01 Maxygen Inc Integrated systems and methods for diversity generation and screening
EP1272967A2 (en) 2000-03-30 2003-01-08 Maxygen, Inc. In silico cross-over site selection
JP2004508011A (ja) 2000-04-03 2004-03-18 マキシジェン, インコーポレイテッド スブチリシン変異体
US7049485B2 (en) 2000-10-20 2006-05-23 Board Of Trustees Of Michigan State University Transgenic plants containing ligninase and cellulase which degrade lignin and cellulose to fermentable sugars
US7747391B2 (en) 2002-03-01 2010-06-29 Maxygen, Inc. Methods, systems, and software for identifying functional biomolecules
US20050084907A1 (en) 2002-03-01 2005-04-21 Maxygen, Inc. Methods, systems, and software for identifying functional biomolecules
EP1493027B1 (en) 2002-03-01 2014-10-15 Codexis Mayflower Holdings, LLC Methods, systems, and software for identifying functional bio-molecules
US7620500B2 (en) 2002-03-09 2009-11-17 Maxygen, Inc. Optimization of crossover points for directed evolution
US20090183270A1 (en) 2002-10-02 2009-07-16 Adams Thomas R Transgenic plants with enhanced agronomic traits
EP1654354A1 (en) 2003-08-11 2006-05-10 Codexis, Inc. Improved ketoreductase polypeptides and related polynucleotides
US7923552B2 (en) 2004-10-18 2011-04-12 SGF Holdings, LLC High yield method of producing pure rebaudioside A
US9386797B2 (en) 2011-02-17 2016-07-12 Purecircle Sdn Bhd Glucosyl stevia composition
EP2155869A2 (en) 2007-05-30 2010-02-24 Danisco US, INC., Genencor Division Variants of an alpha-amylase with improved production levels in fermentation processes
US8093028B2 (en) 2007-07-24 2012-01-10 Wisconsin Alumni Research Foundation Engineered glycosyltransferases with expanded substrate specificity
US8768871B2 (en) 2008-02-12 2014-07-01 Codexis, Inc. Method of generating an optimized, diverse population of variants
US8504498B2 (en) 2008-02-12 2013-08-06 Codexis, Inc. Method of generating an optimized, diverse population of variants
WO2009149577A1 (en) 2008-06-13 2009-12-17 Givaudan Sa Methods of identifying modulators of the bitter taste receptor tas2r44
EP3023494B1 (en) 2008-06-13 2018-11-28 Codexis, Inc. Method of synthesizing polynucleotide variants
US8383346B2 (en) 2008-06-13 2013-02-26 Codexis, Inc. Combined automated parallel synthesis of polynucleotide variants
US20090312196A1 (en) 2008-06-13 2009-12-17 Codexis, Inc. Method of synthesizing polynucleotide variants
ES2592377T3 (es) 2008-10-03 2016-11-29 Morita Kagaku Kogyo Co., Ltd. Nuevos glucósidos de esteviol
US8753861B2 (en) 2008-11-11 2014-06-17 Danisco Us Inc. Protease comprising one or more combinable mutations
US11155888B2 (en) 2010-03-12 2021-10-26 Purecircle Usa Inc. Stevia composition, production method and uses
US20150344512A1 (en) 2011-12-19 2015-12-03 Purecircle Usa Inc. Methods of purifying steviol glycosides and uses of the same
EP2544538B1 (en) 2010-03-12 2022-06-15 PureCircle USA Inc. High-purity steviol glycosides
EP2575432B1 (en) 2010-06-02 2019-08-14 Evolva, Inc. Recombinant production of steviol glycosides
US9029426B2 (en) 2010-12-13 2015-05-12 Purecircle Sdn Bhd Highly soluble Rebaudioside D
US20140030381A1 (en) 2011-02-17 2014-01-30 Purecircle Usa Inc. Glucosyl stevia composition
US8733641B1 (en) 2011-06-14 2014-05-27 Digital Processing Systems, LLC. Electronic kiosk system and method for dispensing medical smart cards and managing healthcare information and services
EP2726651B1 (en) 2011-06-28 2018-11-07 Codexis, Inc. Protein variant generation by region shuffling
CA3128532A1 (en) 2011-08-08 2013-02-14 Evolva Sa Recombinant production of steviol glycosides
EP4124245A1 (en) 2011-12-19 2023-02-01 The Coca-Cola Company Beverage comprising rebaudioside x
MX355028B (es) 2012-01-23 2018-03-28 Dsm Ip Assets Bv Produccion de diterpeno.
US10000783B2 (en) 2012-03-16 2018-06-19 Suntory Holdings Limited Steviol glucosyltransferases and genes encoding the same
WO2013159055A1 (en) 2012-04-20 2013-10-24 Codexis, Inc. Production of fatty alcohols from engineered microorganisms
MX395285B (es) 2012-05-22 2025-03-25 Purecircle Sdn Bhd Glucosidos de esteviol de alta pureza.
US9752174B2 (en) 2013-05-28 2017-09-05 Purecircle Sdn Bhd High-purity steviol glycosides
TW201402599A (zh) 2012-05-30 2014-01-16 Suntory Holdings Ltd 甜菊糖苷糖苷轉化酵素及編碼該酵素之基因
MX2015003684A (es) 2012-09-25 2015-06-15 Cargill Inc Mezclas de esteviosidos.
EP2928321A1 (en) 2012-12-05 2015-10-14 Evolva SA Steviol glycoside compositions sensory properties
US20140171519A1 (en) 2012-12-19 2014-06-19 Indra Prakash Compositions and methods for improving rebaudioside x solubility
EP4414988A3 (en) 2013-01-31 2024-11-06 Codexis, Inc. Methods, systems, and software for identifying bio-molecules using models of multiplicative form
MY199452A (en) 2013-02-06 2023-10-30 Evolva Sa Methods for improved production of rebaudioside d and rebaudioside m
BR112015019160A2 (pt) 2013-02-11 2017-08-22 Dalgaard Mikkelsen Michael Produção de glicosídeos de esteviol em hospedeiros recombinantes
KR101404728B1 (ko) 2013-02-28 2014-06-09 씨제이제일제당 (주) 스테비오사이드로부터 리바우디오사이드 a를 제조하는 방법
US9717267B2 (en) 2013-03-14 2017-08-01 The Coca-Cola Company Beverages containing rare sugars
US20140322389A1 (en) 2013-03-14 2014-10-30 Indra Prakash Beverages containing rare sugars
US20140272068A1 (en) 2013-03-14 2014-09-18 Indra Prakash Beverages containing rare sugars
WO2014153000A1 (en) 2013-03-14 2014-09-25 Chromocell Corporation Compounds, compositions, and methods for modulating sweet taste
US20160029677A1 (en) 2013-03-15 2016-02-04 The Coca-Cola Company Novel glucosyl steviol glycosides, their compositions and their purification
EP2970354B1 (en) 2013-03-15 2018-05-30 The Coca-Cola Company Steviol glycosides and their compositions
US20140342044A1 (en) 2013-05-14 2014-11-20 Pepsico, Inc. Compositions and Comestibles
US20140342043A1 (en) 2013-05-14 2014-11-20 Pepsico, Inc. Rebaudioside Sweetener Compositions and Food Products Sweetened with Same
CA2912347A1 (en) 2013-05-31 2014-12-04 Dsm Ip Assets B.V. Extracellular diterpene production
US10039834B2 (en) 2013-07-12 2018-08-07 The Coca-Cola Company Compositions and methods using rebaudioside X to provide sweetness enhancement
US10905146B2 (en) 2013-07-12 2021-02-02 The Coca-Cola Company Compositions for improving rebaudioside M solubility
EP3021689B1 (en) 2013-07-15 2021-03-24 DSM IP Assets B.V. Diterpene production
EP3024941B1 (en) 2013-07-23 2019-07-03 DSM IP Assets B.V. Diterpene production in yarrowia
EP3536697A1 (en) 2013-07-31 2019-09-11 DSM IP Assets B.V. Recovery of steviol glycosides
CN103397064B (zh) 2013-08-14 2015-04-15 苏州汉酶生物技术有限公司 一种酶法制备瑞鲍迪甙m的方法
US20160235102A1 (en) 2013-09-23 2016-08-18 Almendra Americas, LLC Sweetener composition, sweetener products, and methods of sweetening
AU2014342939B2 (en) 2013-11-01 2018-03-22 Conagen Inc. Recombinant production of steviol glycosides
CN106471128A (zh) 2014-01-28 2017-03-01 百事可乐公司 一种酶法制备瑞鲍迪甙m的方法
US20150223505A1 (en) 2014-02-12 2015-08-13 Purecircle Usa Inc. Stevia composition, production method and uses
US10609942B2 (en) 2015-01-06 2020-04-07 James and Carol May Family, LLLP Compositions and methods for sweeteners
US10772346B2 (en) 2014-02-21 2020-09-15 James and Carol May Family, LLLP Compositions and methods for the solubilization of stevia glycosides
WO2015152707A1 (en) 2014-04-02 2015-10-08 Purecircle Sdn Bhd Compounds produced from stevia and process for producing the same
US20180020709A1 (en) 2014-04-16 2018-01-25 Purecircle Usa Inc. Rebaudioside m biosynthetic production and recovery methods
US9522929B2 (en) 2014-05-05 2016-12-20 Conagen Inc. Non-caloric sweetener
US10264811B2 (en) 2014-05-19 2019-04-23 Epc Natural Products Co., Ltd. Stevia sweetener with improved solubility
GB2526383B (en) 2014-05-20 2018-01-31 Tate & Lyle Ingredients Americas Llc Improved sweetener
US10357052B2 (en) 2014-06-16 2019-07-23 Sweet Green Fields USA LLC Rebaudioside A and stevioside with improved solubilities
US10485256B2 (en) 2014-06-20 2019-11-26 Sweet Green Fields International Co., Limited Stevia sweetener with improved solubility with a cyclodextrin
CN104151378A (zh) 2014-08-12 2014-11-19 济南汉定生物工程有限公司 一种甜菊糖甙rm的提纯方法
EP3683315A1 (en) 2014-08-19 2020-07-22 Purecircle SDN BHD Method for preparing rebaudioside m
WO2016036980A1 (en) 2014-09-03 2016-03-10 Chromocell Corporation Compounds, compositions, and methods for modulating sweet taste
IL234525B (en) 2014-09-08 2018-05-31 Unavoo Food Tech Ltd The composition containing a filler and a flavoring agent and its use
CA2960693A1 (en) 2014-09-09 2016-03-17 Evolva Sa Production of steviol glycosides in recombinant hosts
ES2903031T3 (es) 2014-09-11 2022-03-30 Pepsico Inc Potenciador de dulzor
EP4166010A1 (en) 2014-09-19 2023-04-19 PureCircle SDN BHD High-purity steviol glycosides
KR101765369B1 (ko) 2014-09-19 2017-08-08 한국과학기술원 돌외 유래의 신규한 당전이효소 및 이의 용도
BR112017006163B1 (pt) * 2014-10-03 2022-04-05 Conagen Inc Produto de consumo oral e método para adoçar o mesmo
EP3204506B1 (en) 2014-10-08 2022-01-12 DSM IP Assets B.V. Steviol glycoside production
CN107109453A (zh) 2014-11-05 2017-08-29 马努斯生物合成股份有限公司 甜菊醇糖苷的微生物产生
US20160165941A1 (en) 2014-11-21 2016-06-16 Flipn'Sweet, LLC Sugar substitute compositions comprising digestion resistent soluble fiber
US20170258121A1 (en) 2014-11-24 2017-09-14 Cargill, Incorporated Glycoside compositions
CN107249356B (zh) 2014-12-17 2021-08-06 嘉吉公司 用于口服摄入或使用的甜菊醇糖苷化合物、组合物以及用于增强甜菊醇糖苷溶解度的方法
EP3245196A4 (en) 2015-01-13 2018-06-13 Chromocell Corporation Compounds, compositions, and methods for modulating sweet taste
EP3250686A1 (en) 2015-01-30 2017-12-06 Evolva SA Production of steviol glycosides in recombinant hosts
CA3220591A1 (en) 2015-03-11 2016-09-15 Morita Kagaku Kogyo Co., Ltd. Sweetner composition and food containing same
WO2016146711A1 (en) 2015-03-16 2016-09-22 Dsm Ip Assets B.V. Udp-glycosyltransferases
CA2979957A1 (en) 2015-03-23 2016-09-29 Dsm Ip Assets B.V. Udp-glycosyltransferases from solanum lycopersicum
KR102569053B1 (ko) * 2015-04-14 2023-08-21 코나겐 인크. 조작된 전체 세포 촉매를 사용한 비칼로리 감미료의 제조
CA2985669C (en) 2015-05-20 2022-05-03 Cargill, Incorporated Glycoside compositions
US10612065B2 (en) 2015-05-29 2020-04-07 Cargill, Incorporated Heat treatment to produce glycosides
EP3303552A4 (en) 2015-05-29 2019-01-16 Cargill, Incorporated FERMENTATION METHOD FOR THE PRODUCTION OF STEVIOL GLYCOSIDES WITH MULTIPHASE SUPPLY
EP3303553B1 (en) 2015-05-29 2022-07-27 Cargill, Incorporated Fermentation methods for producing steviol glycosides using high ph
CN105200098A (zh) 2015-06-30 2015-12-30 苏州汉酶生物技术有限公司 一种利用酿酒酵母酶法制备瑞鲍迪甙m的方法
US10517321B2 (en) 2015-07-10 2019-12-31 Sweet Green Fields USA LLC Compositions of steviol multiglycosylated derivatives and stevia components
CN107820394A (zh) 2015-07-10 2018-03-20 帝斯曼知识产权资产管理有限公司 甜菊醇糖苷组合物
US11124535B2 (en) 2015-07-10 2021-09-21 Dsm Ip Assets B.V. Steviol glycoside composition
US10844414B2 (en) 2015-08-06 2020-11-24 Cargill, Incorporated Methods for producing steviol glycosides in engineered yeast
US20190203244A1 (en) 2015-08-20 2019-07-04 Pepsico, Inc. Preparation of rebaudioside m in a single reaction vessel
WO2017053980A1 (en) 2015-09-25 2017-03-30 The Coca-Cola Company Steviol glycoside blends, compositions and methods
EP4190172B1 (en) 2015-10-02 2025-11-26 The Coca-Cola Company Sweetener composition comprising steviol glycoside sweeteners with improved flavor profiles
US20170105432A1 (en) 2015-10-16 2017-04-20 Senomyx, Inc. Sweetener and flavor enhancer formulations
WO2017068017A1 (en) 2015-10-23 2017-04-27 Dsm Ip Assets B.V. Low sugar flavoured yogurt
US11647771B2 (en) 2015-10-26 2023-05-16 Purecircle Usa Inc. Steviol glycoside compositions
WO2017093895A1 (en) 2015-11-30 2017-06-08 Purecircle Sdn Bhd Process for producing high purity steviol glycosides
EP3387136B1 (en) 2015-12-10 2022-01-05 Evolva SA Production of steviol glycosides in recombinant hosts
PL3393258T3 (pl) 2015-12-24 2026-02-23 Danone Us, Llc Sposób wytwarzania odcedzanego fermentowanego produktu mlecznego z zastosowaniem laktazy
CN108777992A (zh) 2016-01-07 2018-11-09 谱赛科美国股份有限公司 高溶解性甜菊醇糖苷
US20190021382A1 (en) 2016-03-01 2019-01-24 Wm. Wrigley Jr. Company Long-lasting sweetener formulations
US20170258120A1 (en) 2016-03-09 2017-09-14 Merisant US, Inc. Liquid sweetener compositions
WO2017156432A1 (en) 2016-03-10 2017-09-14 Chromocell Corporation Steviol glycoside esters
US11149050B2 (en) 2016-03-14 2021-10-19 Purecircle Usa Inc. Highly soluble steviol glycosides
US20190116835A1 (en) 2016-03-28 2019-04-25 The Coca-Cola Company Sweetness and Taste Improvement of Steviol Glycoside or Mogroside Sweeteners with Flavonids
CN109152393A (zh) 2016-03-31 2019-01-04 三得利控股株式会社 含有甜菊的饮料
ES2980286T3 (es) 2016-03-31 2024-09-30 Suntory Holdings Ltd Bebida que contiene estevia
AU2017246876B2 (en) 2016-04-06 2021-09-23 The Coca-Cola Company Sweetness and taste improvement of steviol glycoside or mogroside sweeteners
US10982249B2 (en) 2016-04-13 2021-04-20 Evolva Sa Production of steviol glycosides in recombinant hosts
WO2017189778A1 (en) 2016-04-26 2017-11-02 Chromocell Corporation Methods, compounds, and compositions, for modulating sweet taste
US20190124953A1 (en) 2016-04-29 2019-05-02 Pepsico, Inc. Novel steviol glycosides blends
US11985995B2 (en) 2016-05-10 2024-05-21 The Coca-Cola Company Methods of freeze drying compositions containing rebaudioside M and rebaudioside D
WO2017207484A1 (en) * 2016-05-31 2017-12-07 Universiteit Gent Mutant sucrose synthases and their uses
US20170352267A1 (en) 2016-06-02 2017-12-07 GM Global Technology Operations LLC Systems for providing proactive infotainment at autonomous-driving vehicles
BR112018076109B1 (pt) 2016-06-14 2022-11-01 Purecircle Usa Inc Processo para produzir uma composição de glicosídeos de esteviol, composição adoçante, composição de paladar, ingrediente alimentar e alimento, bebida, produto cosmético e farmacêutico
US20190127772A1 (en) * 2016-06-15 2019-05-02 Codexis, Inc. Enzymatic glycosylation of steviol glycosides and other compounds with glucose-1-phosphate
CN108135238A (zh) 2016-08-04 2018-06-08 百事可乐公司 甜味剂组合物
WO2018029272A1 (en) 2016-08-09 2018-02-15 Dsm Ip Assets B.V. Crystallization of steviol glycosides
CA3033243A1 (en) 2016-08-09 2018-02-15 Dsm Ip Assets B.V. Crystallization of steviol glycosides
PT3497222T (pt) 2016-08-12 2022-02-09 Amyris Inc Glicosiltransferase dependente de udp para produção de eficácia elevada de rebaudiosídeos
US10085472B2 (en) 2016-08-29 2018-10-02 Pepsico, Inc. Compositions comprising rebaudioside J
KR102905512B1 (ko) * 2017-02-03 2025-12-29 테이트 앤드 라일 솔루션스 유에스에이 엘엘씨 조작된 글리코실트랜스퍼라제 및 스테비올 글리코시드 글루코실화 방법
CN106866757B (zh) 2017-03-16 2020-06-26 诸城市浩天药业有限公司 甜菊糖m苷晶型及制备方法和用途
US20170354175A1 (en) 2017-05-15 2017-12-14 Senomyx, Inc. Sweetener composition
CA3103514A1 (en) * 2018-07-09 2020-01-16 Codexis, Inc. Engineered galactose oxidase variant enzymes
IL280302B2 (en) 2018-07-30 2025-09-01 Codexis Inc Engineered glycosyltransferases and methods for glycosylation of steviol glycoside

Similar Documents

Publication Publication Date Title
JP2024116190A5 (https=)
JP2024114921A5 (https=)
JP2024161376A5 (https=)
JP2024036694A5 (https=)
JP2024032941A5 (https=)
JP2025176106A5 (https=)
JP2022184985A5 (https=)
JP2025069142A5 (https=)
JP2024150466A5 (https=)
JP2025098156A5 (https=)
JPWO2021237223A5 (https=)
JP2025094038A5 (https=)
JP2025090801A5 (https=)
JP2024149687A5 (https=)
JP2024099585A5 (https=)
JP2024099716A5 (https=)
JP2025084821A5 (https=)
JPWO2023196444A5 (https=)
JP2025148617A5 (https=)
JP2023156274A5 (https=)
JP2023085264A5 (https=)
JP2024059782A5 (https=)
JP2025003964A5 (https=)
JP2024073452A5 (https=)
JP2023078173A5 (https=)