|
US3700612A
(en)
|
1971-06-23 |
1972-10-24 |
Tenneco Chem |
Aqueous surface-coating compositions containing hydroxyalkyl ethers of galactomannan gums as thickeners
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
GB8422653D0
(en)
|
1984-09-07 |
1984-10-10 |
Technology Licence Co Ltd |
Monoclonal antibodies
|
|
US5057540A
(en)
|
1987-05-29 |
1991-10-15 |
Cambridge Biotech Corporation |
Saponin adjuvant
|
|
US4912094B1
(en)
|
1988-06-29 |
1994-02-15 |
Ribi Immunochem Research Inc. |
Modified lipopolysaccharides and process of preparation
|
|
US5370872A
(en)
|
1991-08-12 |
1994-12-06 |
Swiss Serum And Vaccine Institute Berne |
Escherichia coliO-polysaccharide-protein conjugate vaccine
|
|
ES2204900T3
(es)
|
1992-02-11 |
2004-05-01 |
Henry M. Jackson Foundation For The Advancement Of Military Medicine |
Estructura inmuinogena de doble vector.
|
|
CA2138997C
(en)
|
1992-06-25 |
2003-06-03 |
Jean-Paul Prieels |
Vaccine composition containing adjuvants
|
|
ATE280235T1
(de)
|
1993-03-05 |
2004-11-15 |
Wyeth Corp |
Plasmid zur herstellung von crm-protein und diphtherie-toxin
|
|
WO1995008348A1
(en)
|
1993-09-22 |
1995-03-30 |
Henry M. Jackson Foundation For The Advancement Of Military Medicine |
Method of activating soluble carbohydrate using novel cyanylating reagents for the production of immunogenic constructs
|
|
AUPM399594A0
(en)
|
1994-02-21 |
1994-03-17 |
Csl Limited |
Antigenic preparation for treatment or prevention of helicobacter infection
|
|
FI102976B
(fi)
|
1994-02-28 |
1999-03-31 |
Valtion Teknillinen |
Menetelmä lisäkeittokemikaalien tuottamiseksi sekä käyttämiseksi sulfa attiselluloosaprosessissa
|
|
NZ304715A
(en)
|
1995-03-22 |
1999-07-29 |
Jackson H M Found Military Med |
Production of immunogenic constructs using organic cyanylating reagents to activate carbohydrates and then coupling the carbohydrate to a protein, peptide or hapten
|
|
US6299881B1
(en)
|
1997-03-24 |
2001-10-09 |
Henry M. Jackson Foundation For The Advancement Of Military Medicine |
Uronium salts for activating hydroxyls, carboxyls, and polysaccharides, and conjugate vaccines, immunogens, and other useful immunological reagents produced using uronium salts
|
|
US6491919B2
(en)
|
1997-04-01 |
2002-12-10 |
Corixa Corporation |
Aqueous immunologic adjuvant compostions of monophosphoryl lipid A
|
|
CN1326564C
(zh)
|
1997-04-01 |
2007-07-18 |
科里克萨有限公司 |
单磷酰基脂质a的水性免疫佐剂组合物
|
|
US6858211B1
(en)
|
1998-07-20 |
2005-02-22 |
The United States Of America As Represented By The Department Of Health And Human Services |
Vaccines against Escherichia coli O157 infection
|
|
KR100629028B1
(ko)
|
1998-10-16 |
2006-09-26 |
글락소스미스클라인 바이오로지칼즈 에스.에이. |
애쥬번트 시스템 및 백신
|
|
ES2309064T3
(es)
|
2000-04-13 |
2008-12-16 |
Corixa Corporation |
Composiciones inmunoestimulantes que comprenden un fosfato de aminoalquil glucosaminida y qs-21.
|
|
WO2001078787A2
(en)
|
2000-04-18 |
2001-10-25 |
Endobiologics, Incorporated |
Lipopolysaccharide-conjugate vaccine for sepsis treatment
|
|
RU2189253C1
(ru)
|
2001-04-09 |
2002-09-20 |
Государственный научный центр прикладной микробиологии |
Диагностикум для идентификации escherichia coli o157 : h7 и способ его получения
|
|
US6676958B2
(en)
|
2001-06-19 |
2004-01-13 |
Advanced Bioadjuvants, Llc |
Adjuvant composition for mucosal and injection delivered vaccines
|
|
AU2003217912A1
(en)
|
2002-03-01 |
2003-09-16 |
Xencor |
Antibody optimization
|
|
IL163806A0
(en)
|
2002-03-07 |
2005-12-18 |
Eidgenoess Tech Hochschule |
System and method for the production of recombinant glycosylated proteins in a prokaryotic host
|
|
AU2003901008A0
(en)
|
2003-03-04 |
2003-03-20 |
Anadis Ltd |
Composition for the treatment and prevention of bacterial infections
|
|
CN1324134C
(zh)
|
2003-12-22 |
2007-07-04 |
南开大学 |
对大肠杆菌o81型的o－抗原特异的核苷酸
|
|
AU2005229434B2
(en)
|
2004-03-30 |
2010-09-30 |
Nsgene A/S |
Therapeutic use of a growth factor, NsG33
|
|
ES2353814T3
(es)
|
2005-05-11 |
2011-03-07 |
Eth Zuerich |
Proteinas n-glicosiladas recombinantes de celulas procariotas.
|
|
TWI457133B
(zh)
|
2005-12-13 |
2014-10-21 |
Glaxosmithkline Biolog Sa |
新穎組合物
|
|
US8063063B2
(en)
|
2006-03-23 |
2011-11-22 |
Novartis Ag |
Immunopotentiating compounds
|
|
ES2536426T3
(es)
|
2006-03-23 |
2015-05-25 |
Novartis Ag |
Compuestos de imidazoquinoxalina como inmunomoduladores
|
|
JP4791866B2
(ja)
|
2006-03-24 |
2011-10-12 |
国立大学法人秋田大学 |
下痢原性大腸菌感染症の判別に用いられる固相等
|
|
US8877688B2
(en)
|
2007-09-14 |
2014-11-04 |
Adimab, Llc |
Rationally designed, synthetic antibody libraries and uses therefor
|
|
EP3124497B1
(en)
|
2007-09-14 |
2020-04-15 |
Adimab, LLC |
Rationally designed, synthetic antibody libraries and uses therefor
|
|
CA2711503A1
(en)
|
2008-01-08 |
2009-07-16 |
Biogenerix Ag |
Glycoconjugation of polypeptides using oligosaccharyltransferases
|
|
CN101983070B
(zh)
|
2008-02-20 |
2016-03-30 |
格林考瓦因有限公司 |
由来源于原核细胞的重组n-糖基化蛋白制备生物共轭物
|
|
CA2760096C
(en)
|
2009-04-27 |
2018-10-30 |
Immuron Limited |
Anti-lps enriched immunoglobulin preparation for use in treatment and/or prophylaxis of a pathologic disorder.
|
|
CA2764374C
(en)
|
2009-06-05 |
2019-11-19 |
Infectious Disease Research Institute |
Synthetic glucopyranosyl lipid adjuvants
|
|
NO2501406T3
(https=)
|
2009-11-19 |
2018-05-19 |
|
|
|
KR102318383B1
(ko)
|
2010-07-16 |
2021-10-27 |
아디맵 엘엘씨 |
항체 라이브러리
|
|
CA2819366A1
(en)
|
2010-12-10 |
2012-06-14 |
Merck Sharp & Dohme Corp. |
Novel formulations which mitigate agitation-induced aggregation of immunogenic compositions
|
|
US20140336366A1
(en)
|
2011-09-06 |
2014-11-13 |
Glycovaxyn Ag |
Bioconjugate vaccines made in prokaryotic cells
|
|
US9932598B2
(en)
|
2012-08-02 |
2018-04-03 |
The Regents Of The University Of California |
Metabolic engineering of microbial organisms
|
|
DK2885007T3
(en)
|
2012-08-16 |
2018-12-03 |
Pfizer |
Methods for glycoconjugation and compositions
|
|
BR112015004817A2
(pt)
|
2012-09-10 |
2017-07-04 |
Glycovaxyn Ag |
bioconjugados compreendendo antígenos modificados e seus usos
|
|
ES2905107T3
(es)
|
2012-10-12 |
2022-04-07 |
Glaxosmithkline Biologicals Sa |
Procedimientos de modificación de células hospedadoras
|
|
EP3508579B1
(en)
|
2012-11-07 |
2021-06-30 |
GlaxoSmithKline Biologicals SA |
Production of recombinant vaccine in e. coli by enzymatic conjugation
|
|
JP6502262B2
(ja)
|
2012-12-20 |
2019-04-17 |
ファイザー・インク |
糖複合化方法
|
|
ES2750525T3
(es)
|
2012-12-27 |
2020-03-26 |
Glaxosmithkline Biologicals Sa |
Procedimientos y composiciones relacionados con CRM197
|
|
PL2945651T3
(pl)
|
2013-01-17 |
2018-08-31 |
Arsanis Biosciences Gmbh |
Przeciwciało swoiste wobec E.coli MDR
|
|
PE20160080A1
(es)
|
2013-05-18 |
2016-02-21 |
Aduro Biotech Inc |
Composiciones y metodos para activar la senalizacion que depende del estimulador del gen de interferon
|
|
CN103495161B
(zh)
|
2013-10-08 |
2019-06-18 |
江苏康泰生物医学技术有限公司 |
一种多元肺炎球菌荚膜多糖-蛋白质结合物的混合物及其制备方法
|
|
MX371513B
(es)
|
2013-10-11 |
2020-01-31 |
Glaxosmithkline Biologicals Sa |
Metodos de modificacion de celulas huespedes.
|
|
EP2870974A1
(en)
|
2013-11-08 |
2015-05-13 |
Novartis AG |
Salmonella conjugate vaccines
|
|
US10195262B2
(en)
|
2013-12-04 |
2019-02-05 |
Glaxosmithkline Biologicals S.A. |
Prevention of Staphylococcus aureus infections by glycoprotein vaccines synthesized in Escherichia coli
|
|
WO2015117711A1
(en)
|
2014-02-06 |
2015-08-13 |
Arsanis Biosciences Gmbh |
E. coli specific antibody sequences
|
|
WO2015124769A1
(en)
|
2014-02-24 |
2015-08-27 |
Glycovaxyn Ag |
Novel polysaccharide and uses thereof
|
|
CA2945542C
(en)
|
2014-04-17 |
2024-03-05 |
Glycovaxyn Ag |
Modified host cells and uses thereof
|
|
CN105695497B
(zh)
|
2014-11-27 |
2019-09-24 |
中国人民解放军军事医学科学院生物工程研究所 |
一种细菌多糖修饰的重组融合蛋白的制备方法及其应用
|
|
CN107614679B
(zh)
|
2014-12-30 |
2026-04-07 |
葛兰素史密丝克莱恩生物有限公司 |
用于蛋白糖基化的组合物和方法
|
|
TWI715617B
(zh)
*
|
2015-08-24 |
2021-01-11 |
比利時商葛蘭素史密斯克藍生物品公司 |
對抗腸道外病原性大腸桿菌之免疫保護之方法及組合物
|
|
GB201518668D0
(en)
|
2015-10-21 |
2015-12-02 |
Glaxosmithkline Biolog Sa |
Immunogenic Comosition
|
|
GB201610599D0
(en)
|
2016-06-17 |
2016-08-03 |
Glaxosmithkline Biologicals Sa |
Immunogenic Composition
|
|
AR109621A1
(es)
|
2016-10-24 |
2018-12-26 |
Janssen Pharmaceuticals Inc |
Formulaciones de vacunas contra glucoconjugados de expec
|
|
GB201711635D0
(en)
|
2017-07-19 |
2017-08-30 |
Glaxosmithkline Biologicals Sa |
Immunogenic composition
|
|
US11260119B2
(en)
*
|
2018-08-24 |
2022-03-01 |
Pfizer Inc. |
Escherichia coli compositions and methods thereof
|
|
CN113227125A
(zh)
|
2018-12-12 |
2021-08-06 |
葛兰素史密丝克莱恩生物有限公司 |
用于o-连接的糖基化的修饰的载体蛋白
|
|
IL286467B2
(en)
*
|
2019-03-18 |
2026-02-01 |
Janssen Pharmaceuticals Inc |
Methods for producing bioconjugates of polysaccharides E. coli o-antigen, preparations thereof and methods for using them
|
|
CA3134216A1
(en)
*
|
2019-03-18 |
2020-09-24 |
Janssen Pharmaceuticals, Inc. |
Bioconjugates of e. coli o-antigen polysaccharides, methods of production thereof, and methods of use thereof
|
|
FR3098334B1
(fr)
|
2019-07-05 |
2021-07-23 |
Airbus Operations Sas |
Procédé et système de surveillance d’un état de conscience d’un opérateur dans un poste de pilotage d’un aéronef
|
|
IL307247A
(en)
*
|
2021-04-01 |
2023-11-01 |
Janssen Pharmaceuticals Inc |
Production of E. Coli O18 bioconjugates
|