SG11201602546RA - Methods of host cell modification - Google Patents
Methods of host cell modificationInfo
- Publication number
- SG11201602546RA SG11201602546RA SG11201602546RA SG11201602546RA SG11201602546RA SG 11201602546R A SG11201602546R A SG 11201602546RA SG 11201602546R A SG11201602546R A SG 11201602546RA SG 11201602546R A SG11201602546R A SG 11201602546RA SG 11201602546R A SG11201602546R A SG 11201602546RA
- Authority
- SG
- Singapore
- Prior art keywords
- methods
- host cell
- cell modification
- modification
- host
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0258—Escherichia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0283—Shigella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/104—Pseudomonadales, e.g. Pseudomonas
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/00041—Use of virus, viral particle or viral elements as a vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/30—Vector systems comprising sequences for excision in presence of a recombinase, e.g. loxP or FRT
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361889672P | 2013-10-11 | 2013-10-11 | |
| PCT/EP2014/071889 WO2015052344A1 (en) | 2013-10-11 | 2014-10-13 | Methods of host cell modification |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201602546RA true SG11201602546RA (en) | 2016-04-28 |
Family
ID=51726490
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201602546RA SG11201602546RA (en) | 2013-10-11 | 2014-10-13 | Methods of host cell modification |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11220676B2 (en) |
| EP (1) | EP3055416B1 (en) |
| JP (1) | JP2016533719A (en) |
| KR (1) | KR20160062169A (en) |
| CN (1) | CN106062203B (en) |
| BR (1) | BR112016007727A8 (en) |
| CA (1) | CA2926523C (en) |
| EA (1) | EA201690529A1 (en) |
| ES (1) | ES2778074T3 (en) |
| IL (1) | IL244791A0 (en) |
| MX (1) | MX371513B (en) |
| SG (1) | SG11201602546RA (en) |
| WO (1) | WO2015052344A1 (en) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9849169B2 (en) | 2013-01-17 | 2017-12-26 | Arsanis Biosciences Gmbh | MDR E. coli specific antibody |
| MX371513B (en) | 2013-10-11 | 2020-01-31 | Glaxosmithkline Biologicals Sa | Methods of host cell modification. |
| FI3110441T3 (en) | 2014-02-24 | 2024-05-06 | Glaxosmithkline Biologicals Sa | Novel polysaccharide and uses thereof |
| CN106794237B (en) * | 2014-04-17 | 2022-04-12 | 葛兰素史密丝克莱恩生物有限公司 | Modified host cells and uses thereof |
| TWI715617B (en) | 2015-08-24 | 2021-01-11 | 比利時商葛蘭素史密斯克藍生物品公司 | Methods and compositions for immune protection against extra-intestinal pathogenic e. coli |
| AR109621A1 (en) | 2016-10-24 | 2018-12-26 | Janssen Pharmaceuticals Inc | FORMULATIONS OF VACCINES AGAINST GLUCOCONJUGADOS OF EXPEC |
| GB201712678D0 (en) | 2017-08-07 | 2017-09-20 | Glaxosmithkline Biologicals Sa | Process for the manipulation of nucleic acids |
| EP3492482A1 (en) * | 2017-11-30 | 2019-06-05 | Vaxxilon AG | Vaccine against klebsiella pneumoniae |
| CN108611306B (en) * | 2018-04-03 | 2021-05-25 | 华南农业大学 | Method for researching gene function of bradyrhizobium |
| CN108531439B (en) * | 2018-04-16 | 2020-04-07 | 南京工业大学 | Escherichia coli genetic engineering bacterium and construction method and application thereof |
| CN108774628B (en) * | 2018-07-02 | 2022-03-25 | 南开大学 | Escherichia coli engineering bacterium for synthesizing neonatal meningitis escherichia coli glycoprotein conjugate vaccine and application |
| US11260119B2 (en) | 2018-08-24 | 2022-03-01 | Pfizer Inc. | Escherichia coli compositions and methods thereof |
| AU2020240075A1 (en) | 2019-03-18 | 2021-10-14 | Janssen Pharmaceuticals, Inc. | Methods of producing bioconjugates of e. coli o-antigen polysaccharides, compositions thereof, and methods of use thereof |
| WO2020191082A1 (en) | 2019-03-18 | 2020-09-24 | Janssen Pharmaceuticals, Inc. | Bioconjugates of e. coli o-antigen polysaccharides, methods of production thereof, and methods of use thereof |
| JP2021000041A (en) * | 2019-06-24 | 2021-01-07 | トヨタ自動車株式会社 | Helper plasmid for transformation, method for producing transformant using the same, and transformation method |
| CA3173729A1 (en) * | 2020-02-23 | 2021-08-26 | Pfizer Inc. | Escherichia coli compositions and methods thereof |
| KR102160203B1 (en) * | 2020-06-15 | 2020-09-25 | 서울시립대학교 산학협력단 | Manufacturing method of mutant strain having increased deinoxanthin productivity and the method for deinoxanthin overproduction by controlling cultivation temperature |
| WO2021259742A1 (en) | 2020-06-25 | 2021-12-30 | Glaxosmithkline Biologicals Sa | Modified exotoxin a proteins |
| JP7517002B2 (en) | 2020-09-10 | 2024-07-17 | トヨタ自動車株式会社 | Method for producing a transformant and transformation method |
| AU2021342797B2 (en) | 2020-09-17 | 2024-02-08 | Janssen Pharmaceuticals, Inc. | Multivalent vaccine compositions and uses thereof |
| PE20231934A1 (en) * | 2020-10-27 | 2023-12-01 | Pfizer | COMPOSITIONS OF ESCHERICHIA COLI AND METHODS THEREOF |
| JP2022087881A (en) * | 2020-12-02 | 2022-06-14 | トヨタ自動車株式会社 | Plasmid for transformation, method for producing transformant using the same, and transformation method |
| JP2022099381A (en) * | 2020-12-23 | 2022-07-05 | トヨタ自動車株式会社 | Helper plasmid for transformation, method for producing transformant using the same, and method of transformation |
| JP2022099419A (en) * | 2020-12-23 | 2022-07-05 | トヨタ自動車株式会社 | Plasmid for transformation, method for producing transformant using the same, and method of transformation |
| CN113388596B (en) * | 2021-08-16 | 2021-12-07 | 翌圣生物科技(上海)股份有限公司 | High-fidelity Pfu DNA polymerase mutant, coding DNA thereof and application thereof in NGS |
| JP2024139548A (en) * | 2023-03-27 | 2024-10-09 | 株式会社豊田中央研究所 | Gene Expression Methods |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2607595C (en) * | 2005-05-11 | 2018-11-27 | Eth Zuerich | Recombinant n-glycosylated proteins from procaryotic cells |
| SG10201400320TA (en) * | 2008-02-20 | 2014-05-29 | Glycovaxyn Ag | Bioconjugates made from recombinant n-glycosylated proteins from procaryotic cells |
| GB0915403D0 (en) | 2009-09-04 | 2009-10-07 | London School Hygiene & Tropical Medicine | Protein glycosylation |
| HUE038456T2 (en) | 2009-11-19 | 2018-10-29 | Glaxosmithkline Biologicals Sa | Biosynthetic system that produces immunogenic polysaccharides in prokaryotic cells |
| HUE037956T2 (en) * | 2010-05-06 | 2018-09-28 | Glaxosmithkline Biologicals Sa | Capsular gram-positive bacteria bioconjugate vaccines |
| CA2847621A1 (en) * | 2011-09-06 | 2013-03-14 | Glycovaxyn Ag | Bioconjugate vaccines made in prokaryotic cells |
| CA2853338A1 (en) * | 2011-10-28 | 2013-05-02 | Merck Sharp & Dohme Corp. | Methods for increasing n-glycan occupancy and reducing production of hybrid n-glycans in pichia pastoris strains lacking alg3 expression |
| KR20150054800A (en) * | 2012-09-10 | 2015-05-20 | 글리코박신 아게 | Bioconjugates comprising modified antigens and uses thereof |
| ES2905107T3 (en) | 2012-10-12 | 2022-04-07 | Glaxosmithkline Biologicals Sa | Host cell modification procedures |
| CA3125293A1 (en) * | 2012-11-07 | 2014-05-15 | Glaxosmithkline Biologicals Sa | Production of recombinant vaccine in e. coli by enzymatic conjugation |
| MX371513B (en) | 2013-10-11 | 2020-01-31 | Glaxosmithkline Biologicals Sa | Methods of host cell modification. |
-
2014
- 2014-10-13 MX MX2016004575A patent/MX371513B/en active IP Right Grant
- 2014-10-13 CN CN201480066861.8A patent/CN106062203B/en active Active
- 2014-10-13 SG SG11201602546RA patent/SG11201602546RA/en unknown
- 2014-10-13 JP JP2016521754A patent/JP2016533719A/en active Pending
- 2014-10-13 US US15/028,483 patent/US11220676B2/en active Active
- 2014-10-13 KR KR1020167012152A patent/KR20160062169A/en not_active Application Discontinuation
- 2014-10-13 BR BR112016007727A patent/BR112016007727A8/en not_active Application Discontinuation
- 2014-10-13 EA EA201690529A patent/EA201690529A1/en unknown
- 2014-10-13 CA CA2926523A patent/CA2926523C/en active Active
- 2014-10-13 EP EP14784209.0A patent/EP3055416B1/en active Active
- 2014-10-13 WO PCT/EP2014/071889 patent/WO2015052344A1/en active Application Filing
- 2014-10-13 ES ES14784209T patent/ES2778074T3/en active Active
-
2016
- 2016-03-28 IL IL244791A patent/IL244791A0/en unknown
-
2021
- 2021-12-03 US US17/541,454 patent/US20220186196A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20220186196A1 (en) | 2022-06-16 |
| BR112016007727A2 (en) | 2017-09-12 |
| CN106062203A (en) | 2016-10-26 |
| IL244791A0 (en) | 2016-04-21 |
| KR20160062169A (en) | 2016-06-01 |
| US11220676B2 (en) | 2022-01-11 |
| CA2926523C (en) | 2023-09-26 |
| CN106062203B (en) | 2020-08-07 |
| MX371513B (en) | 2020-01-31 |
| MX2016004575A (en) | 2016-07-12 |
| US20170121691A1 (en) | 2017-05-04 |
| BR112016007727A8 (en) | 2018-01-30 |
| EP3055416B1 (en) | 2020-01-22 |
| ES2778074T3 (en) | 2020-08-07 |
| EP3055416A1 (en) | 2016-08-17 |
| CA2926523A1 (en) | 2015-04-16 |
| JP2016533719A (en) | 2016-11-04 |
| WO2015052344A1 (en) | 2015-04-16 |
| EA201690529A1 (en) | 2016-11-30 |
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