JP2024161376A5 - - Google Patents
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- JP2024161376A5 JP2024161376A5 JP2024114477A JP2024114477A JP2024161376A5 JP 2024161376 A5 JP2024161376 A5 JP 2024161376A5 JP 2024114477 A JP2024114477 A JP 2024114477A JP 2024114477 A JP2024114477 A JP 2024114477A JP 2024161376 A5 JP2024161376 A5 JP 2024161376A5
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862631304P | 2018-02-15 | 2018-02-15 | |
| US62/631,304 | 2018-02-15 | ||
| US201862720525P | 2018-08-21 | 2018-08-21 | |
| US62/720,525 | 2018-08-21 | ||
| JP2020531575A JP7109547B2 (ja) | 2018-02-15 | 2019-02-15 | 真核ゲノム修飾のための操作されたＣａｓ９システム |
| PCT/US2019/018335 WO2019161290A1 (en) | 2018-02-15 | 2019-02-15 | Engineered cas9 systems for eukaryotic genome modification |
| JP2022083820A JP7559005B2 (ja) | 2018-02-15 | 2022-05-23 | 真核ゲノム修飾のための操作されたＣａｓ９システム |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022083820A Division JP7559005B2 (ja) | 2018-02-15 | 2022-05-23 | 真核ゲノム修飾のための操作されたＣａｓ９システム |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024161376A JP2024161376A (ja) | 2024-11-19 |
| JP2024161376A5 true JP2024161376A5 (https=) | 2025-01-14 |
Family
ID=65995829
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020531575A Active JP7109547B2 (ja) | 2018-02-15 | 2019-02-15 | 真核ゲノム修飾のための操作されたＣａｓ９システム |
| JP2022083820A Active JP7559005B2 (ja) | 2018-02-15 | 2022-05-23 | 真核ゲノム修飾のための操作されたＣａｓ９システム |
| JP2024114477A Pending JP2024161376A (ja) | 2018-02-15 | 2024-07-18 | 真核ゲノム修飾のための操作されたＣａｓ９システム |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020531575A Active JP7109547B2 (ja) | 2018-02-15 | 2019-02-15 | 真核ゲノム修飾のための操作されたＣａｓ９システム |
| JP2022083820A Active JP7559005B2 (ja) | 2018-02-15 | 2022-05-23 | 真核ゲノム修飾のための操作されたＣａｓ９システム |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US10767193B2 (https=) |
| EP (1) | EP3752607A1 (https=) |
| JP (3) | JP7109547B2 (https=) |
| KR (3) | KR102465067B1 (https=) |
| CN (1) | CN111902536B (https=) |
| AU (3) | AU2019222568B2 (https=) |
| BR (1) | BR112020010479A2 (https=) |
| CA (2) | CA3281020A1 (https=) |
| IL (2) | IL274528B2 (https=) |
| SG (1) | SG11202007382TA (https=) |
| WO (1) | WO2019161290A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2015330699B2 (en) | 2014-10-10 | 2021-12-02 | Editas Medicine, Inc. | Compositions and methods for promoting homology directed repair |
| US11111492B2 (en) * | 2017-03-06 | 2021-09-07 | Florida State University Research Foundation, Inc. | Genome engineering methods using a cytosine-specific Cas9 |
| KR20210045360A (ko) | 2018-05-16 | 2021-04-26 | 신테고 코포레이션 | 가이드 rna 설계 및 사용을 위한 방법 및 시스템 |
| EP3823633A4 (en) | 2018-06-29 | 2023-05-03 | Editas Medicine, Inc. | SYNTHETIC LEAD MOLECULES, COMPOSITIONS AND METHODS RELATED THERETO |
| US10913941B2 (en) | 2019-02-14 | 2021-02-09 | Metagenomi Ip Technologies, Llc | Enzymes with RuvC domains |
| US10947517B2 (en) | 2019-02-15 | 2021-03-16 | Sigma-Aldrich Co. Llc | CRISPR/Cas fusion proteins and systems |
| MX2021010559A (es) | 2019-03-07 | 2021-12-15 | Univ California | Polipéptidos efectores de crispr-cas y métodos de uso de estos. |
| IL292517A (en) | 2019-12-17 | 2022-06-01 | Sigma Aldrich Co Llc | Genome editing in Bacteroidetes |
| GB2594339B (en) * | 2020-02-14 | 2023-02-08 | Metagenomi Inc | Enzymes with RUVC domains |
| US20230058352A1 (en) * | 2020-03-11 | 2023-02-23 | Sigma-Aldrich Co. Llc | High Fidelity SpCas9 Nucleases for Genome Modification |
| WO2021202568A1 (en) | 2020-03-31 | 2021-10-07 | Metagenomi Ip Technologies, Llc | Class ii, type ii crispr systems |
| CN112159801B (zh) * | 2020-07-13 | 2022-11-15 | 复旦大学 | SlugCas9-HF蛋白、含有SlugCas9-HF蛋白的基因编辑系统及应用 |
| KR102679001B1 (ko) * | 2020-09-21 | 2024-06-28 | 고려대학교 산학협력단 | 신규의 개량된 염기 편집 또는 교정용 융합단백질 및 이의 용도 |
| US20220145334A1 (en) * | 2020-11-06 | 2022-05-12 | Pairwise Plants Services, Inc. | Compositions and methods for rna-encoded dna-replacement of alleles |
| CN113717960B (zh) * | 2021-08-27 | 2023-07-18 | 电子科技大学 | 一种新Cas9蛋白、CRISPR-Cas9基因组定向编辑载体及基因组编辑方法 |
| AU2022335499A1 (en) | 2021-08-27 | 2024-02-22 | Metagenomi Therapeutics, Inc. | Enzymes with ruvc domains |
| AU2022396533A1 (en) | 2021-11-24 | 2024-05-02 | Metagenomi Therapeutics, Inc. | Endonuclease systems |
| CN114657181B (zh) * | 2022-04-01 | 2023-08-25 | 安徽大学 | 一种靶向H1.4的sgRNA以及H1.4基因编辑方法 |
| EP4592322A1 (en) * | 2022-09-23 | 2025-07-30 | Chuang, Woei-jer | Fusion protein targeting intergrin alpha(iib)beta3 and containing tissue plasminogen activator or variant thereof and use thereof |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA04005010A (es) | 2001-11-26 | 2005-04-08 | Advanced Cell Tech Inc | METODO PARA HACER Y USAR NUCLEOS CELULARES SOMáTICOS METODOS PARA HACER Y USAR NUCLEOS CELULARES SOMáTICOS HUMANOS REPROGRAMADOS Y CELULAS DEL TALLO HUMANAS AUTOLOGAS E ISOGENICAS. |
| AU2013266968B2 (en) | 2012-05-25 | 2017-06-29 | Emmanuelle CHARPENTIER | Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription |
| PL3360964T3 (pl) * | 2012-12-06 | 2020-03-31 | Sigma-Aldrich Co. Llc | Modyfikacja i regulacja genomu oparta na crispr |
| EP2840140B2 (en) * | 2012-12-12 | 2023-02-22 | The Broad Institute, Inc. | Crispr-Cas based method for mutation of prokaryotic cells |
| WO2014197748A2 (en) | 2013-06-05 | 2014-12-11 | Duke University | Rna-guided gene editing and gene regulation |
| US9074199B1 (en) * | 2013-11-19 | 2015-07-07 | President And Fellows Of Harvard College | Mutant Cas9 proteins |
| JP2017503514A (ja) * | 2014-01-24 | 2017-02-02 | ノースカロライナ ステート ユニバーシティーＮｏｒｔｈ Ｃａｒｏｌｉｎａ Ｓｔａｔｅ Ｕｎｉｖｅｒｓｉｔｙ | Ｃａｓ９ターゲッティングをガイドする配列に関する方法および組成物 |
| EP3122880B1 (en) * | 2014-03-26 | 2021-05-05 | Editas Medicine, Inc. | Crispr/cas-related methods and compositions for treating sickle cell disease |
| EP3186375A4 (en) * | 2014-08-28 | 2019-03-13 | North Carolina State University | Novel CAS9 PROTEINS AND CHARACTERISTICS FOR DNA TARGETING AND GENOME EDITING |
| EP3201340B1 (en) * | 2014-10-01 | 2020-12-02 | The General Hospital Corporation | Methods for increasing efficiency of nuclease-induced homology-directed repair |
| CA3209273A1 (en) * | 2016-06-02 | 2017-12-07 | Sigma-Aldrich Co. Llc | Using programmable dna binding proteins to enhance targeted genome modification |
| AU2017280353B2 (en) | 2016-06-24 | 2021-11-11 | Inscripta, Inc. | Methods for generating barcoded combinatorial libraries |
| JP7305534B2 (ja) | 2016-07-06 | 2023-07-10 | バーテックス ファーマシューティカルズ インコーポレイテッド | 疼痛関連障害を処置するための物質及び方法 |
| BR112019012155A2 (pt) * | 2016-12-14 | 2019-11-12 | Wageningen Universiteit | uso de pelo menos uma molécula-guia de rna e uma proteína cas, método de ligação, clivagem, marcação ou modificação de um polinucleotídeo alvo de fita dupla, célula transformada, e, complexo de nucleoproteína |
| KR102655021B1 (ko) * | 2017-07-11 | 2024-04-04 | 시그마-알드리치 컴퍼니., 엘엘씨 | 표적된 게놈 변형을 개선하기 위한 뉴클레오솜 상호작용 단백질 도메인 사용 |
| SG11202000840YA (en) * | 2017-07-31 | 2020-02-27 | Reflection Biotechnologies Ltd | Cellular models of and therapies for ocular diseases |
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2019
- 2019-02-15 KR KR1020207026571A patent/KR102465067B1/ko active Active
- 2019-02-15 SG SG11202007382TA patent/SG11202007382TA/en unknown
- 2019-02-15 AU AU2019222568A patent/AU2019222568B2/en active Active
- 2019-02-15 US US16/277,823 patent/US10767193B2/en active Active
- 2019-02-15 JP JP2020531575A patent/JP7109547B2/ja active Active
- 2019-02-15 CA CA3281020A patent/CA3281020A1/en active Pending
- 2019-02-15 WO PCT/US2019/018335 patent/WO2019161290A1/en not_active Ceased
- 2019-02-15 CA CA3084020A patent/CA3084020C/en active Active
- 2019-02-15 CN CN201980013625.2A patent/CN111902536B/zh active Active
- 2019-02-15 BR BR112020010479-5A patent/BR112020010479A2/pt unknown
- 2019-02-15 EP EP19714890.1A patent/EP3752607A1/en active Pending
- 2019-02-15 IL IL274528A patent/IL274528B2/en unknown
- 2019-02-15 KR KR1020227002190A patent/KR102494449B1/ko active Active
- 2019-02-15 KR KR1020237003098A patent/KR102684890B1/ko active Active
- 2019-02-15 IL IL321024A patent/IL321024A/en unknown
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2020
- 2020-07-30 US US16/943,813 patent/US12297449B2/en active Active
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2022
- 2022-01-11 AU AU2022200130A patent/AU2022200130B2/en active Active
- 2022-05-23 JP JP2022083820A patent/JP7559005B2/ja active Active
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2024
- 2024-04-04 AU AU2024202158A patent/AU2024202158A1/en active Pending
- 2024-07-18 JP JP2024114477A patent/JP2024161376A/ja active Pending