LT3240895T - Kompozicijos ir būdai, skirti baltymų glikozilinimui - Google Patents

Kompozicijos ir būdai, skirti baltymų glikozilinimui

Info

Publication number
LT3240895T
LT3240895T LTEPPCT/EP2015/081229T LT15081229T LT3240895T LT 3240895 T LT3240895 T LT 3240895T LT 15081229 T LT15081229 T LT 15081229T LT 3240895 T LT3240895 T LT 3240895T
Authority
LT
Lithuania
Prior art keywords
compositions
methods
protein glycosylation
glycosylation
protein
Prior art date
Application number
LTEPPCT/EP2015/081229T
Other languages
English (en)
Inventor
Jurgen Haas
Julian Ihssen
Michael Thomas KOWARIK
Torsten Franz SCHWEDE
Linda Christiane THÖNY-MEYER
Original Assignee
Glaxosmithkline Biologicals S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals S.A. filed Critical Glaxosmithkline Biologicals S.A.
Publication of LT3240895T publication Critical patent/LT3240895T/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1081Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/005Glycopeptides, glycoproteins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
LTEPPCT/EP2015/081229T 2014-12-30 2015-12-24 Kompozicijos ir būdai, skirti baltymų glikozilinimui LT3240895T (lt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462097975P 2014-12-30 2014-12-30
US201462098071P 2014-12-30 2014-12-30
PCT/EP2015/081229 WO2016107818A1 (en) 2014-12-30 2015-12-24 Compositions and methods for protein glycosylation

Publications (1)

Publication Number Publication Date
LT3240895T true LT3240895T (lt) 2022-04-11

Family

ID=55080101

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/EP2015/081229T LT3240895T (lt) 2014-12-30 2015-12-24 Kompozicijos ir būdai, skirti baltymų glikozilinimui

Country Status (18)

Country Link
US (3) US10150952B2 (lt)
EP (2) EP4043561A1 (lt)
JP (1) JP6850724B2 (lt)
CN (1) CN107614679A (lt)
BE (1) BE1022998B1 (lt)
BR (1) BR112017014031B1 (lt)
CA (1) CA2971653C (lt)
CY (1) CY1125392T1 (lt)
DK (1) DK3240895T3 (lt)
ES (1) ES2907211T3 (lt)
HR (1) HRP20220500T1 (lt)
HU (1) HUE057726T2 (lt)
LT (1) LT3240895T (lt)
MX (1) MX2017008817A (lt)
PL (1) PL3240895T3 (lt)
PT (1) PT3240895T (lt)
SI (1) SI3240895T1 (lt)
WO (2) WO2016107818A1 (lt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014111516A1 (en) 2013-01-17 2014-07-24 Arsanis Biosciences Gmbh Mdr e. coli specific antibody
LT3110441T (lt) 2014-02-24 2024-04-25 Glaxosmithkline Biologicals S.A. Naujas polisacharidas ir jo panaudojimas
PT3240895T (pt) 2014-12-30 2022-03-02 Glaxosmithkline Biologicals Sa Composições e métodos para glicosilação de proteínas
AU2016224006B8 (en) 2015-02-26 2020-03-19 Vaxnewmo Llc Acinetobacter O-oligosaccharyltransferases and uses thereof
TWI715617B (zh) 2015-08-24 2021-01-11 比利時商葛蘭素史密斯克藍生物品公司 對抗腸道外病原性大腸桿菌之免疫保護之方法及組合物
AR109621A1 (es) 2016-10-24 2018-12-26 Janssen Pharmaceuticals Inc Formulaciones de vacunas contra glucoconjugados de expec
GB201704117D0 (en) * 2017-03-15 2017-04-26 London School Hygiene & Tropical Medicine Oligosaccharyl Transferase polypeptide
GB201721582D0 (en) 2017-12-21 2018-02-07 Glaxosmithkline Biologicals Sa S aureus antigens and immunogenic compositions
GB201721576D0 (en) 2017-12-21 2018-02-07 Glaxosmithkline Biologicals Sa Hla antigens and glycoconjugates thereof
CA3103474A1 (en) 2018-06-16 2019-12-19 Vaxnewmo Llc Glycosylated comp pilin variants, methods of making and uses thereof
WO2020131236A1 (en) * 2018-12-21 2020-06-25 Vaxnewmo Llc O-linked glycosylation recognition motifs
WO2020191082A1 (en) 2019-03-18 2020-09-24 Janssen Pharmaceuticals, Inc. Bioconjugates of e. coli o-antigen polysaccharides, methods of production thereof, and methods of use thereof
AR118389A1 (es) * 2019-03-18 2021-09-29 Janssen Pharmaceuticals Inc Métodos de producción de bioconjugados de polisacáridos de e. coli o-antígeno, sus composiciones y métodos de utilización
EP3770269A1 (en) * 2019-07-23 2021-01-27 GlaxoSmithKline Biologicals S.A. Quantification of bioconjugate glycosylation
EP4010467B1 (en) * 2019-08-09 2024-04-24 GlaxoSmithKline Biologicals SA Mutated pglb oligosaccharyltransferase enzymes
EP3777884A1 (en) 2019-08-15 2021-02-17 GlaxoSmithKline Biologicals S.A. Immunogenic composition
CN110910960B (zh) * 2019-11-30 2022-07-08 浙江天科高新技术发展有限公司 一种鲍曼不动杆菌分子血清型快速分析方法
IL301248B2 (en) 2020-09-17 2024-04-01 Janssen Pharmaceuticals Inc Multivalent vaccine compositions and their uses
EP4291673A2 (en) * 2021-02-11 2023-12-20 GlaxoSmithKline Biologicals SA Mutated pglb oligosaccharyltransferase enzymes
CA3215752A1 (en) 2021-04-01 2022-10-06 Janssen Pharmaceuticals, Inc. Production of e. coli o18 bioconjugates
WO2023118033A1 (en) 2021-12-22 2023-06-29 Glaxosmithkline Biologicals Sa Vaccine

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006245969B8 (en) * 2005-05-11 2011-08-25 Eth Zurich Recombinant N-glycosylated proteins from procaryotic cells
DK2240595T4 (da) * 2008-01-03 2019-10-07 Cornell Res Foundation Inc Glykosyleret proteinekspression i prokaryoter
US8895014B2 (en) * 2008-02-20 2014-11-25 Glycovaxyn Ag Bioconjugates made from recombinant N-glycosylated proteins from procaryotic cells
AU2010322454B2 (en) * 2009-11-19 2016-05-19 Glaxosmithkline Biologicals S.A. Biosynthetic system that produces immunogenic polysaccharides in prokaryotic cells
CN103079591B (zh) 2010-05-06 2017-07-28 格林考瓦因有限公司 荚膜革兰氏阳性细菌生物缀合物疫苗
WO2013067523A1 (en) * 2011-11-04 2013-05-10 Cornell University A prokaryote-based cell-free system for the synthesis of glycoproteins
WO2014111724A1 (en) * 2013-01-18 2014-07-24 London School Of Hygiene And Tropical Medicine Glycosylation method
PT3240895T (pt) 2014-12-30 2022-03-02 Glaxosmithkline Biologicals Sa Composições e métodos para glicosilação de proteínas
GB201704117D0 (en) * 2017-03-15 2017-04-26 London School Hygiene & Tropical Medicine Oligosaccharyl Transferase polypeptide

Also Published As

Publication number Publication date
CA2971653C (en) 2024-06-11
US20180002679A1 (en) 2018-01-04
US11015177B2 (en) 2021-05-25
BR112017014031B1 (pt) 2023-11-07
US10577592B2 (en) 2020-03-03
WO2016107819A1 (en) 2016-07-07
JP2018500912A (ja) 2018-01-18
SI3240895T1 (sl) 2022-04-29
CY1125392T1 (el) 2024-02-16
EP4043561A1 (en) 2022-08-17
EP3240895A1 (en) 2017-11-08
PL3240895T3 (pl) 2022-05-02
BE1022998A1 (fr) 2016-10-28
ES2907211T3 (es) 2022-04-22
US20200181586A1 (en) 2020-06-11
WO2016107818A1 (en) 2016-07-07
PT3240895T (pt) 2022-03-02
US20190078064A1 (en) 2019-03-14
WO2016107818A8 (en) 2017-08-31
BR112017014031A2 (pt) 2018-01-16
MX2017008817A (es) 2017-10-24
DK3240895T3 (da) 2022-04-11
JP6850724B2 (ja) 2021-03-31
EP3240895B1 (en) 2022-01-26
BE1022998B1 (fr) 2016-10-28
US10150952B2 (en) 2018-12-11
HUE057726T2 (hu) 2022-06-28
CN107614679A (zh) 2018-01-19
HRP20220500T1 (hr) 2022-06-10
CA2971653A1 (en) 2016-07-07

Similar Documents

Publication Publication Date Title
HK1257295A1 (zh) 用於免疫腫瘤學的組合物和方法
IL262321A (en) Preparations and methods for selective protein expression
SI3240895T1 (sl) Sestavki in postopki za glikozilacijo proteinov
HK1244185A1 (zh) 用於生成卵清蛋白的方法和組合物
HK1253306A1 (zh) 抗ntb-a抗體及相關組合物和方法
GB2546350B (en) Compositions and methods
GB2535253B (en) Compositions and methods
GB201502305D0 (en) Protein
GB201502306D0 (en) Protein
SG11201704010UA (en) Fibroin-derived protein composition
GB201718876D0 (en) Antithrombin-heparin compositions and methods
IL250902A0 (en) Anti-met antibodies and preparations
IL246879A0 (en) Preparations of Epilimod and methods of using them
HK1245158A1 (zh) 阿吡莫德組合物及其使用方法
HUE050893T2 (hu) Protein
GB201415344D0 (en) Protein
PL3099793T3 (pl) Białko
GB201512996D0 (en) Compositions and methods
GB201522610D0 (en) Protein
GB201514413D0 (en) Compositions and methods
GB201402915D0 (en) Compositions and methods
IL256261B (en) Hide1 compositions and methods
GB201522554D0 (en) Methods and compositions
GB201518167D0 (en) Methods and compositions
GB201514415D0 (en) Compositions and methods