LT3240895T - Compositions and methods for protein glycosylation - Google Patents

Compositions and methods for protein glycosylation

Info

Publication number
LT3240895T
LT3240895T LTEPPCT/EP2015/081229T LT15081229T LT3240895T LT 3240895 T LT3240895 T LT 3240895T LT 15081229 T LT15081229 T LT 15081229T LT 3240895 T LT3240895 T LT 3240895T
Authority
LT
Lithuania
Prior art keywords
compositions
methods
protein glycosylation
glycosylation
protein
Prior art date
Application number
LTEPPCT/EP2015/081229T
Other languages
Lithuanian (lt)
Inventor
Jurgen Haas
Julian Ihssen
Michael Thomas KOWARIK
Torsten Franz SCHWEDE
Linda Christiane THÖNY-MEYER
Original Assignee
Glaxosmithkline Biologicals S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals S.A. filed Critical Glaxosmithkline Biologicals S.A.
Publication of LT3240895T publication Critical patent/LT3240895T/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1081Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/005Glycopeptides, glycoproteins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
LTEPPCT/EP2015/081229T 2014-12-30 2015-12-24 Compositions and methods for protein glycosylation LT3240895T (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462097975P 2014-12-30 2014-12-30
US201462098071P 2014-12-30 2014-12-30
PCT/EP2015/081229 WO2016107818A1 (en) 2014-12-30 2015-12-24 Compositions and methods for protein glycosylation

Publications (1)

Publication Number Publication Date
LT3240895T true LT3240895T (en) 2022-04-11

Family

ID=55080101

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEPPCT/EP2015/081229T LT3240895T (en) 2014-12-30 2015-12-24 Compositions and methods for protein glycosylation

Country Status (18)

Country Link
US (3) US10150952B2 (en)
EP (2) EP3240895B1 (en)
JP (1) JP6850724B2 (en)
CN (1) CN107614679A (en)
BE (1) BE1022998B1 (en)
BR (1) BR112017014031B1 (en)
CA (1) CA2971653C (en)
CY (1) CY1125392T1 (en)
DK (1) DK3240895T3 (en)
ES (1) ES2907211T3 (en)
HR (1) HRP20220500T1 (en)
HU (1) HUE057726T2 (en)
LT (1) LT3240895T (en)
MX (1) MX2017008817A (en)
PL (1) PL3240895T3 (en)
PT (1) PT3240895T (en)
SI (1) SI3240895T1 (en)
WO (2) WO2016107819A1 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9849169B2 (en) 2013-01-17 2017-12-26 Arsanis Biosciences Gmbh MDR E. coli specific antibody
FI3110441T3 (en) 2014-02-24 2024-05-06 Glaxosmithkline Biologicals Sa Novel polysaccharide and uses thereof
US10150952B2 (en) 2014-12-30 2018-12-11 Glaxosmithkline Biologicals S.A. Compositions and methods for protein glycosylation
AU2016224006B8 (en) 2015-02-26 2020-03-19 Vaxnewmo Llc Acinetobacter O-oligosaccharyltransferases and uses thereof
TWI715617B (en) 2015-08-24 2021-01-11 比利時商葛蘭素史密斯克藍生物品公司 Methods and compositions for immune protection against extra-intestinal pathogenic e. coli
AR109621A1 (en) 2016-10-24 2018-12-26 Janssen Pharmaceuticals Inc FORMULATIONS OF VACCINES AGAINST GLUCOCONJUGADOS OF EXPEC
GB201704117D0 (en) 2017-03-15 2017-04-26 London School Hygiene & Tropical Medicine Oligosaccharyl Transferase polypeptide
GB201721576D0 (en) 2017-12-21 2018-02-07 Glaxosmithkline Biologicals Sa Hla antigens and glycoconjugates thereof
GB201721582D0 (en) 2017-12-21 2018-02-07 Glaxosmithkline Biologicals Sa S aureus antigens and immunogenic compositions
CA3103474A1 (en) 2018-06-16 2019-12-19 Vaxnewmo Llc Glycosylated comp pilin variants, methods of making and uses thereof
JP2022514704A (en) * 2018-12-21 2022-02-14 ヴァックスニューモ エルエルシー O-linked glycosylation recognition motif
WO2020191082A1 (en) 2019-03-18 2020-09-24 Janssen Pharmaceuticals, Inc. Bioconjugates of e. coli o-antigen polysaccharides, methods of production thereof, and methods of use thereof
AU2020240075A1 (en) 2019-03-18 2021-10-14 Janssen Pharmaceuticals, Inc. Methods of producing bioconjugates of e. coli o-antigen polysaccharides, compositions thereof, and methods of use thereof
EP3770269A1 (en) 2019-07-23 2021-01-27 GlaxoSmithKline Biologicals S.A. Quantification of bioconjugate glycosylation
MX2022001606A (en) * 2019-08-09 2022-03-11 Glaxosmithkline Biologicals Sa Mutated pglb oligosaccharyltransferase enzymes.
EP3777884A1 (en) 2019-08-15 2021-02-17 GlaxoSmithKline Biologicals S.A. Immunogenic composition
CN110910960B (en) * 2019-11-30 2022-07-08 浙江天科高新技术发展有限公司 Acinetobacter baumannii molecular serotype rapid analysis method
AU2021342797B2 (en) 2020-09-17 2024-02-08 Janssen Pharmaceuticals, Inc. Multivalent vaccine compositions and uses thereof
EP4291673A2 (en) * 2021-02-11 2023-12-20 GlaxoSmithKline Biologicals SA Mutated pglb oligosaccharyltransferase enzymes
TW202304504A (en) 2021-04-01 2023-02-01 美商詹森藥物公司 Production of e. coli o18 bioconjugates
WO2023118033A1 (en) 2021-12-22 2023-06-29 Glaxosmithkline Biologicals Sa Vaccine

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2607595C (en) * 2005-05-11 2018-11-27 Eth Zuerich Recombinant n-glycosylated proteins from procaryotic cells
CN107119095B (en) * 2008-01-03 2022-07-05 康乃尔研究基金会有限公司 Glycosylated protein expression in prokaryotes
SG10201400320TA (en) * 2008-02-20 2014-05-29 Glycovaxyn Ag Bioconjugates made from recombinant n-glycosylated proteins from procaryotic cells
HUE038456T2 (en) * 2009-11-19 2018-10-29 Glaxosmithkline Biologicals Sa Biosynthetic system that produces immunogenic polysaccharides in prokaryotic cells
HUE037956T2 (en) 2010-05-06 2018-09-28 Glaxosmithkline Biologicals Sa Capsular gram-positive bacteria bioconjugate vaccines
US11193154B2 (en) * 2011-11-04 2021-12-07 Cornell University Prokaryote-based cell-free system for the synthesis of glycoproteins
WO2014111724A1 (en) * 2013-01-18 2014-07-24 London School Of Hygiene And Tropical Medicine Glycosylation method
US10150952B2 (en) 2014-12-30 2018-12-11 Glaxosmithkline Biologicals S.A. Compositions and methods for protein glycosylation
GB201704117D0 (en) * 2017-03-15 2017-04-26 London School Hygiene & Tropical Medicine Oligosaccharyl Transferase polypeptide

Also Published As

Publication number Publication date
HUE057726T2 (en) 2022-06-28
EP3240895A1 (en) 2017-11-08
US20180002679A1 (en) 2018-01-04
BR112017014031B1 (en) 2023-11-07
BR112017014031A2 (en) 2018-01-16
US11015177B2 (en) 2021-05-25
BE1022998B1 (en) 2016-10-28
US20200181586A1 (en) 2020-06-11
HRP20220500T1 (en) 2022-06-10
CA2971653C (en) 2024-06-11
PL3240895T3 (en) 2022-05-02
US10577592B2 (en) 2020-03-03
JP2018500912A (en) 2018-01-18
SI3240895T1 (en) 2022-04-29
CY1125392T1 (en) 2024-02-16
EP3240895B1 (en) 2022-01-26
CA2971653A1 (en) 2016-07-07
PT3240895T (en) 2022-03-02
US20190078064A1 (en) 2019-03-14
CN107614679A (en) 2018-01-19
JP6850724B2 (en) 2021-03-31
WO2016107818A8 (en) 2017-08-31
ES2907211T3 (en) 2022-04-22
US10150952B2 (en) 2018-12-11
WO2016107818A1 (en) 2016-07-07
EP4043561A1 (en) 2022-08-17
MX2017008817A (en) 2017-10-24
BE1022998A1 (en) 2016-10-28
DK3240895T3 (en) 2022-04-11
WO2016107819A1 (en) 2016-07-07

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