PL3240895T3 - Kompozycje i sposoby dla glikozylacji białek - Google Patents

Kompozycje i sposoby dla glikozylacji białek

Info

Publication number
PL3240895T3
PL3240895T3 PL15822948T PL15822948T PL3240895T3 PL 3240895 T3 PL3240895 T3 PL 3240895T3 PL 15822948 T PL15822948 T PL 15822948T PL 15822948 T PL15822948 T PL 15822948T PL 3240895 T3 PL3240895 T3 PL 3240895T3
Authority
PL
Poland
Prior art keywords
compositions
methods
protein glycosylation
glycosylation
protein
Prior art date
Application number
PL15822948T
Other languages
English (en)
Inventor
Jurgen Haas
Julian Ihssen
Michael Thomas KOWARIK
Torsten Franz SCHWEDE
Linda Christiane THÖNY-MEYER
Original Assignee
Glaxosmithkline Biologicals S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Biologicals S.A. filed Critical Glaxosmithkline Biologicals S.A.
Publication of PL3240895T3 publication Critical patent/PL3240895T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1081Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/005Glycopeptides, glycoproteins
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
PL15822948T 2014-12-30 2015-12-24 Kompozycje i sposoby dla glikozylacji białek PL3240895T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462097975P 2014-12-30 2014-12-30
US201462098071P 2014-12-30 2014-12-30
EP15822948.4A EP3240895B1 (en) 2014-12-30 2015-12-24 Compositions and methods for protein glycosylation
PCT/EP2015/081229 WO2016107818A1 (en) 2014-12-30 2015-12-24 Compositions and methods for protein glycosylation

Publications (1)

Publication Number Publication Date
PL3240895T3 true PL3240895T3 (pl) 2022-05-02

Family

ID=55080101

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15822948T PL3240895T3 (pl) 2014-12-30 2015-12-24 Kompozycje i sposoby dla glikozylacji białek

Country Status (18)

Country Link
US (3) US10150952B2 (pl)
EP (2) EP3240895B1 (pl)
JP (1) JP6850724B2 (pl)
CN (1) CN107614679B (pl)
BE (1) BE1022998B1 (pl)
BR (1) BR112017014031B1 (pl)
CA (1) CA2971653C (pl)
CY (1) CY1125392T1 (pl)
DK (1) DK3240895T3 (pl)
ES (1) ES2907211T3 (pl)
HR (1) HRP20220500T1 (pl)
HU (1) HUE057726T2 (pl)
LT (1) LT3240895T (pl)
MX (1) MX389093B (pl)
PL (1) PL3240895T3 (pl)
PT (1) PT3240895T (pl)
SI (1) SI3240895T1 (pl)
WO (2) WO2016107818A1 (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2945651T3 (pl) 2013-01-17 2018-08-31 Arsanis Biosciences Gmbh Przeciwciało swoiste wobec E.coli MDR
WO2015124769A1 (en) 2014-02-24 2015-08-27 Glycovaxyn Ag Novel polysaccharide and uses thereof
CN107614679B (zh) 2014-12-30 2026-04-07 葛兰素史密丝克莱恩生物有限公司 用于蛋白糖基化的组合物和方法
ES3039659T3 (en) 2015-02-26 2025-10-23 Vaxnewmo Llc Acinetobacter o-oligosaccharyltransferases and uses thereof
TWI715617B (zh) 2015-08-24 2021-01-11 比利時商葛蘭素史密斯克藍生物品公司 對抗腸道外病原性大腸桿菌之免疫保護之方法及組合物
AR109621A1 (es) 2016-10-24 2018-12-26 Janssen Pharmaceuticals Inc Formulaciones de vacunas contra glucoconjugados de expec
GB201704117D0 (en) * 2017-03-15 2017-04-26 London School Hygiene & Tropical Medicine Oligosaccharyl Transferase polypeptide
GB201721582D0 (en) 2017-12-21 2018-02-07 Glaxosmithkline Biologicals Sa S aureus antigens and immunogenic compositions
GB201721576D0 (en) 2017-12-21 2018-02-07 Glaxosmithkline Biologicals Sa Hla antigens and glycoconjugates thereof
JP2021528059A (ja) 2018-06-16 2021-10-21 ヴァックスニューモ エルエルシーVaxnewmo Llc グリコシル化されたComPピリンバリアント、製造方法及びその使用
US12350342B2 (en) 2018-12-21 2025-07-08 Vaxnewmo Llc O-linked glycosylation recognition motifs
CA3134216A1 (en) 2019-03-18 2020-09-24 Janssen Pharmaceuticals, Inc. Bioconjugates of e. coli o-antigen polysaccharides, methods of production thereof, and methods of use thereof
IL286467B2 (en) 2019-03-18 2026-02-01 Janssen Pharmaceuticals Inc Methods for producing bioconjugates of polysaccharides E. coli o-antigen, preparations thereof and methods for using them
EP3770269A1 (en) 2019-07-23 2021-01-27 GlaxoSmithKline Biologicals S.A. Quantification of bioconjugate glycosylation
HRP20240776T1 (hr) * 2019-08-09 2024-09-13 Glaxosmithkline Biologicals Sa Mutirani enzimi pglb oligosahariltransferaze
EP3777884A1 (en) 2019-08-15 2021-02-17 GlaxoSmithKline Biologicals S.A. Immunogenic composition
CN110910960B (zh) * 2019-11-30 2022-07-08 浙江天科高新技术发展有限公司 一种鲍曼不动杆菌分子血清型快速分析方法
AU2021342797B2 (en) 2020-09-17 2024-02-08 Janssen Pharmaceuticals, Inc. Multivalent vaccine compositions and uses thereof
EP4291673A2 (en) * 2021-02-11 2023-12-20 GlaxoSmithKline Biologicals SA Mutated pglb oligosaccharyltransferase enzymes
IL307247A (en) 2021-04-01 2023-11-01 Janssen Pharmaceuticals Inc Production of E. Coli O18 bioconjugates
WO2023118033A1 (en) 2021-12-22 2023-06-29 Glaxosmithkline Biologicals Sa Vaccine

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2353814T3 (es) * 2005-05-11 2011-03-07 Eth Zuerich Proteinas n-glicosiladas recombinantes de celulas procariotas.
CN107119095B (zh) * 2008-01-03 2022-07-05 康乃尔研究基金会有限公司 原核生物中的糖基化蛋白表达
CN101983070B (zh) * 2008-02-20 2016-03-30 格林考瓦因有限公司 由来源于原核细胞的重组n-糖基化蛋白制备生物共轭物
NO2501406T3 (pl) * 2009-11-19 2018-05-19
EP3281639B1 (en) 2010-05-06 2020-11-11 GlaxoSmithKline Biologicals S.A. Capsular gram-positive bacteria bioconjugate vaccines
WO2013067523A1 (en) * 2011-11-04 2013-05-10 Cornell University A prokaryote-based cell-free system for the synthesis of glycoproteins
CA2923957C (en) * 2013-01-18 2021-08-31 London School Of Hygiene And Tropical Medicine Glycosylation method
CN107614679B (zh) 2014-12-30 2026-04-07 葛兰素史密丝克莱恩生物有限公司 用于蛋白糖基化的组合物和方法
GB201704117D0 (en) * 2017-03-15 2017-04-26 London School Hygiene & Tropical Medicine Oligosaccharyl Transferase polypeptide

Also Published As

Publication number Publication date
US10150952B2 (en) 2018-12-11
JP6850724B2 (ja) 2021-03-31
CA2971653A1 (en) 2016-07-07
US20190078064A1 (en) 2019-03-14
CN107614679B (zh) 2026-04-07
US20180002679A1 (en) 2018-01-04
MX389093B (es) 2025-03-20
US20200181586A1 (en) 2020-06-11
WO2016107819A1 (en) 2016-07-07
WO2016107818A1 (en) 2016-07-07
BE1022998A1 (fr) 2016-10-28
WO2016107818A8 (en) 2017-08-31
BE1022998B1 (fr) 2016-10-28
HRP20220500T1 (hr) 2022-06-10
LT3240895T (lt) 2022-04-11
SI3240895T1 (sl) 2022-04-29
ES2907211T3 (es) 2022-04-22
PT3240895T (pt) 2022-03-02
BR112017014031A2 (pt) 2018-01-16
CY1125392T1 (el) 2024-02-16
DK3240895T3 (da) 2022-04-11
HUE057726T2 (hu) 2022-06-28
CN107614679A (zh) 2018-01-19
US11015177B2 (en) 2021-05-25
EP3240895A1 (en) 2017-11-08
US10577592B2 (en) 2020-03-03
BR112017014031B1 (pt) 2023-11-07
CA2971653C (en) 2024-06-11
EP4043561A1 (en) 2022-08-17
MX2017008817A (es) 2017-10-24
EP3240895B1 (en) 2022-01-26
JP2018500912A (ja) 2018-01-18

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