SG11202100470WA - Engineered glycosyltransferases and steviol glycoside glucosylation methods - Google Patents
Engineered glycosyltransferases and steviol glycoside glucosylation methodsInfo
- Publication number
- SG11202100470WA SG11202100470WA SG11202100470WA SG11202100470WA SG11202100470WA SG 11202100470W A SG11202100470W A SG 11202100470WA SG 11202100470W A SG11202100470W A SG 11202100470WA SG 11202100470W A SG11202100470W A SG 11202100470WA SG 11202100470W A SG11202100470W A SG 11202100470WA
- Authority
- SG
- Singapore
- Prior art keywords
- steviol glycoside
- engineered glycosyltransferases
- methods
- glycoside glucosylation
- glucosylation methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/256—Polyterpene radicals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
- C12N9/1062—Sucrose synthase (2.4.1.13)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/01013—Sucrose synthase (2.4.1.13)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862712199P | 2018-07-30 | 2018-07-30 | |
| US201862712327P | 2018-07-31 | 2018-07-31 | |
| PCT/US2019/042151 WO2020028039A1 (en) | 2018-07-30 | 2019-07-17 | Engineered glycosyltransferases and steviol glycoside glucosylation methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202100470WA true SG11202100470WA (en) | 2021-02-25 |
Family
ID=69178045
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202100470WA SG11202100470WA (en) | 2018-07-30 | 2019-07-17 | Engineered glycosyltransferases and steviol glycoside glucosylation methods |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11760981B2 (en) |
| EP (1) | EP3830106A4 (en) |
| JP (4) | JP2021532757A (en) |
| KR (1) | KR20210040408A (en) |
| CN (1) | CN112805295A (en) |
| AU (1) | AU2019314181B2 (en) |
| BR (1) | BR112021001661A8 (en) |
| CA (1) | CA3108268A1 (en) |
| IL (1) | IL280302A (en) |
| MX (1) | MX2021001260A (en) |
| SG (1) | SG11202100470WA (en) |
| TW (1) | TW202019951A (en) |
| WO (1) | WO2020028039A1 (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3497222T (en) | 2016-08-12 | 2022-02-09 | Amyris Inc | Udp-dependent glycosyltransferase for high efficiency production of rebaudiosides |
| CN111621482B (en) * | 2020-06-30 | 2022-04-29 | 浙江工业大学 | Glufosinate-ammonium dehydrogenase mutant, gene engineering bacteria and one-pot multi-enzyme synchronous directed evolution method |
| WO2022002918A1 (en) | 2020-07-03 | 2022-01-06 | C-Lecta Gmbh | One-pot cell-free glycosylation process |
| CN112760302B (en) * | 2020-12-23 | 2022-08-26 | 中化健康产业发展有限公司 | Glycosyltransferase StUGT capable of catalyzing rebaudioside A to generate rebaudioside D |
| CN115418358B (en) * | 2021-06-01 | 2024-01-30 | 弈柯莱生物科技(集团)股份有限公司 | Glycosyltransferase and application thereof |
| WO2022253282A1 (en) * | 2021-06-01 | 2022-12-08 | 弈柯莱生物科技(上海)股份有限公司 | Glycosyltransferase and application thereof |
| CN115449514B (en) * | 2021-06-08 | 2023-09-29 | 弈柯莱生物科技(上海)股份有限公司 | Beta-1, 2-glycosyltransferase and application thereof |
| CN113462670B (en) * | 2021-08-23 | 2023-03-24 | 兴化格林生物制品有限公司 | Glycosyltransferase mutant and method for catalytically synthesizing rebaudioside M by using same |
| CN115725528B (en) * | 2021-08-30 | 2024-01-12 | 弈柯莱生物科技(集团)股份有限公司 | Glycosyltransferase and application thereof |
| CN116555210A (en) * | 2022-01-30 | 2023-08-08 | 弈柯莱生物科技(上海)股份有限公司 | Glycosyltransferases and their use in the preparation of rebaudioside E |
| WO2023226978A1 (en) * | 2022-05-23 | 2023-11-30 | 苏州引航生物科技有限公司 | Microbial-derived sucrose synthase and use thereof |
| WO2024050533A2 (en) * | 2022-09-02 | 2024-03-07 | Arzeda Corp. | Compositions and methods for producing rebaudioside m |
| WO2024121721A1 (en) | 2022-12-05 | 2024-06-13 | Tate & Lyle Solutions Usa Llc | Methods for obtaining steviol glycosides |
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| KR20230162160A (en) * | 2017-02-03 | 2023-11-28 | 코덱시스, 인코포레이티드 | Engineered glycosyltransferases and steviol glycoside glucosylation methods |
-
2019
- 2019-07-17 EP EP19843463.1A patent/EP3830106A4/en active Pending
- 2019-07-17 BR BR112021001661A patent/BR112021001661A8/en unknown
- 2019-07-17 MX MX2021001260A patent/MX2021001260A/en unknown
- 2019-07-17 US US16/514,578 patent/US11760981B2/en active Active
- 2019-07-17 AU AU2019314181A patent/AU2019314181B2/en active Active
- 2019-07-17 JP JP2021504769A patent/JP2021532757A/en active Pending
- 2019-07-17 KR KR1020217006167A patent/KR20210040408A/en unknown
- 2019-07-17 CA CA3108268A patent/CA3108268A1/en active Pending
- 2019-07-17 WO PCT/US2019/042151 patent/WO2020028039A1/en active Application Filing
- 2019-07-17 SG SG11202100470WA patent/SG11202100470WA/en unknown
- 2019-07-17 CN CN201980064505.5A patent/CN112805295A/en active Pending
- 2019-07-18 TW TW108125485A patent/TW202019951A/en unknown
-
2021
- 2021-01-20 IL IL280302A patent/IL280302A/en unknown
-
2022
- 2022-07-15 JP JP2022113739A patent/JP2022132485A/en active Pending
- 2022-07-15 JP JP2022113740A patent/JP2023039908A/en active Pending
-
2023
- 2023-08-02 US US18/364,419 patent/US20240010999A1/en active Pending
-
2024
- 2024-06-28 JP JP2024105200A patent/JP2024114921A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3830106A4 (en) | 2022-07-06 |
| AU2019314181B2 (en) | 2024-10-17 |
| US20240010999A1 (en) | 2024-01-11 |
| JP2021532757A (en) | 2021-12-02 |
| KR20210040408A (en) | 2021-04-13 |
| AU2019314181A1 (en) | 2021-02-04 |
| JP2022132485A (en) | 2022-09-08 |
| BR112021001661A2 (en) | 2021-05-04 |
| US20200032227A1 (en) | 2020-01-30 |
| CA3108268A1 (en) | 2020-02-06 |
| WO2020028039A1 (en) | 2020-02-06 |
| IL280302A (en) | 2021-03-01 |
| TW202019951A (en) | 2020-06-01 |
| EP3830106A1 (en) | 2021-06-09 |
| MX2021001260A (en) | 2021-04-12 |
| CN112805295A (en) | 2021-05-14 |
| BR112021001661A8 (en) | 2022-08-09 |
| JP2023039908A (en) | 2023-03-22 |
| US11760981B2 (en) | 2023-09-19 |
| JP2024114921A (en) | 2024-08-23 |
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