BR112019002432A2 - cristalização de glicosídeos de esteviol - Google Patents

cristalização de glicosídeos de esteviol

Info

Publication number
BR112019002432A2
BR112019002432A2 BR112019002432A BR112019002432A BR112019002432A2 BR 112019002432 A2 BR112019002432 A2 BR 112019002432A2 BR 112019002432 A BR112019002432 A BR 112019002432A BR 112019002432 A BR112019002432 A BR 112019002432A BR 112019002432 A2 BR112019002432 A2 BR 112019002432A2
Authority
BR
Brazil
Prior art keywords
crystallization
steviol glycosides
rebaudioside
solution
crystallizing
Prior art date
Application number
BR112019002432A
Other languages
English (en)
Inventor
Galaev Igor
Ranjan Sahoo Manas
Original Assignee
Dsm Ip Assets Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets Bv filed Critical Dsm Ip Assets Bv
Publication of BR112019002432A2 publication Critical patent/BR112019002432A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/256—Polyterpene radicals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
    • A23F3/00—Tea; Tea substitutes; Preparations thereof
    • A23F3/40—Tea flavour; Tea oil; Flavouring of tea or tea extract
    • A23F3/405—Flavouring with flavours other than natural tea flavour or tea oil
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23F—COFFEE; TEA; THEIR SUBSTITUTES; MANUFACTURE, PREPARATION, OR INFUSION THEREOF
    • A23F5/00—Coffee; Coffee substitutes; Preparations thereof
    • A23F5/46—Coffee flavour; Coffee oil; Flavouring of coffee or coffee extract
    • A23F5/465—Flavouring with flavours other than natural coffee flavour or coffee oil
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A23L2/60—Sweeteners
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/33—Artificial sweetening agents containing sugars or derivatives
    • A23L27/36—Terpene glycosides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C07H1/08—Separation; Purification from natural products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
    • C12G3/00—Preparation of other alcoholic beverages
    • C12G3/04—Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
    • C12G3/06—Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs with flavouring ingredients
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12J—VINEGAR; PREPARATION OR PURIFICATION THEREOF
    • C12J1/00—Vinegar; Preparation or purification thereof
    • C12J1/08—Addition of flavouring ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00—Function of food ingredients
    • A23V2200/12—Replacer
    • A23V2200/132—Sugar replacer
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/24—Non-sugar sweeteners
    • A23V2250/258—Rebaudioside
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
    • C12G2200/00—Special features
    • C12G2200/21—Wine additives, e.g. flavouring or colouring agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

um método para purificar rebaudiosídeo a, sendo que o método compreende: (a) fornecer uma solução que compreende rebaudiosídeo a; (b) concentrar a dita solução; e (c) cristalizar, a partir da solução, uma composição de alta pureza que compreende rebaudiosídeo a, para purificar, desse modo, o rebaudiosídeo a.
BR112019002432A 2016-08-09 2017-08-09 cristalização de glicosídeos de esteviol BR112019002432A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662372737P 2016-08-09 2016-08-09
PCT/EP2017/070244 WO2018029274A1 (en) 2016-08-09 2017-08-09 Crystallization of steviol glycosides

Publications (1)

Publication Number Publication Date
BR112019002432A2 true BR112019002432A2 (pt) 2019-06-04

Family

ID=59569343

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112019002432A BR112019002432A2 (pt) 2016-08-09 2017-08-09 cristalização de glicosídeos de esteviol

Country Status (6)

Country Link
US (1) US20190169220A1 (pt)
EP (1) EP3497110A1 (pt)
CN (1) CN109563117A (pt)
BR (1) BR112019002432A2 (pt)
CA (1) CA3033243A1 (pt)
WO (1) WO2018029274A1 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3175100A1 (en) 2017-02-03 2018-08-09 Codexis, Inc. Engineered glycosyltransferases and steviol glycoside glucosylation methods
BR112022018080A2 (pt) * 2020-03-13 2022-10-25 Amyris Inc Composições de adoçante de rebaudiosídeo m
CN115669911A (zh) * 2022-09-22 2023-02-03 湖南绿蔓生物科技股份有限公司 一种含甜叶菊的组合物及应用

Family Cites Families (33)

* Cited by examiner, † Cited by third party
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JPS5523756B2 (pt) 1974-03-28 1980-06-25
WO1990014423A1 (en) 1989-05-18 1990-11-29 The Infergene Company Microorganism transformation
ATE196505T1 (de) 1989-07-07 2000-10-15 Unilever Nv Verfahren zur herstellung eines proteins mittels eines durch mehrfachkopie-integrierung eines expressionsvektors tranformierten pilzes
EP0635574B1 (en) 1993-07-23 2003-04-23 Dsm N.V. Selection marker gene free recombinant strains, a method for obtaining them and the use of these strains
US5962678A (en) * 1996-09-13 1999-10-05 Alberta Research Council Method of extracting selected sweet glycosides from the Stevia rebaudiana plant
DK0979294T3 (en) 1997-04-11 2015-08-31 Dsm Ip Assets Bv Gene conversion AS A TOOL FOR CONSTRUCTION OF RECOMBINANT INDUSTRIAL filamentous fungi
US6265186B1 (en) 1997-04-11 2001-07-24 Dsm N.V. Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal RNA encoding domain, particularly with Kluyveromyces
US6255557B1 (en) * 1998-03-31 2001-07-03 Her Majesty The Queen In Right Of Canada As Represented By The Ministerof Agriculture And Agri-Food Canada Stevia rebaudiana with altered steviol glycoside composition
DE69938129D1 (de) 1998-05-19 2008-03-27 Dsm Ip Assets Bv Verbesserte in vivo-produktion von cephalosporinen
JP2002533092A (ja) 1998-12-22 2002-10-08 デーエスエム・ナムローゼ・フェンノートシャップ セファロスポリンの改良されたｉｎｖｉｖｏ産生
SI1468093T2 (en) 2002-01-23 2018-04-30 Dsm Ip Assets B.V. Fermentation of pentose sugars
SE0202090D0 (sv) 2002-05-08 2002-07-04 Forskarpatent I Syd Ab A modifierd yeast consuming L-arabinose
PL2338895T3 (pl) 2003-05-02 2013-11-29 Cargill Inc Genetycznie modyfikowane gatunki drożdży i sposoby fermentacji z użyciem genetycznie modyfikowanych drożdży
CN101914462B (zh) 2004-07-16 2013-04-24 Dsm知识产权资产有限公司 发酵木糖的真核细胞的代谢工程
US7923552B2 (en) 2004-10-18 2011-04-12 SGF Holdings, LLC High yield method of producing pure rebaudioside A
WO2006096130A1 (en) 2005-03-11 2006-09-14 Forskarpatent I Syd Ab Arabinose- and xylose-fermenting saccharomyces cerevisiae strains
US7862845B2 (en) 2005-10-11 2011-01-04 Purecircle Sdn Bhd Process for manufacturing a sweetener and use thereof
US8791253B2 (en) 2006-06-19 2014-07-29 The Coca-Cola Company Rebaudioside A composition and method for purifying rebaudioside A
US9012626B2 (en) * 2006-06-19 2015-04-21 The Coca-Cola Company Rebaudioside a composition and method for purifying rebaudioside a
US8017168B2 (en) * 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
CN101941997B (zh) * 2006-12-15 2012-02-22 成都华高药业有限公司 莱鲍迪甙a的提取方法
CN101200480B (zh) * 2006-12-15 2011-03-30 成都华高药业有限公司 莱鲍迪甙a的提取方法
CN100500685C (zh) * 2007-08-01 2009-06-17 江南大学 一种从甜菊糖中提取高纯度莱鲍迪a甙的方法
CN101591366B (zh) * 2009-07-07 2012-05-30 天津美伦医药集团有限公司 分离高纯度瑞鲍迪甙a的工艺
CN102050850B (zh) * 2009-10-30 2013-07-10 兴化格林生物制品有限公司 甜菊甙及高纯度莱鲍迪甙a的提取新工艺
CN102260304B (zh) * 2010-05-27 2015-06-10 上海医药工业研究院 一种精制纯化莱鲍迪甙a的方法
CN102199178A (zh) * 2011-04-10 2011-09-28 胡玮 莱鲍迪糖苷ra的提取工艺
DK2806754T3 (en) 2012-01-23 2019-02-18 Dsm Ip Assets Bv Diterpene PREPARATION
US20150342234A1 (en) * 2012-12-05 2015-12-03 Evolva Sa Steviol Glycoside Compositions Sensory Properties
CN108064135A (zh) 2013-07-15 2018-05-22 帝斯曼知识产权资产管理有限公司 二萜的生产
CN103739640B (zh) * 2014-01-30 2016-08-17 诸城市浩天药业有限公司 一种甜菊糖a苷晶体及其制备方法和用途
CN104725444A (zh) * 2015-03-24 2015-06-24 杨健 高效能制备高纯度莱鲍迪甙a的方法
WO2017009293A1 (en) * 2015-07-10 2017-01-19 Dsm Ip Assets B.V. Steviol glycoside composition

Also Published As

Publication number Publication date
CA3033243A1 (en) 2018-02-15
US20190169220A1 (en) 2019-06-06
WO2018029274A1 (en) 2018-02-15
CN109563117A (zh) 2019-04-02
EP3497110A1 (en) 2019-06-19

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Legal Events

Date Code Title Description
B15K Others concerning applications: alteration of classification

Free format text: AS CLASSIFICACOES ANTERIORES ERAM: C07H 1/06 , C07H 15/256 , A23L 2/60

Ipc: A23L 2/60 (2006.01), C07H 15/256 (2006.01), C07H 1

B350 Update of information on the portal [chapter 15.35 patent gazette]
B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements