JP2024023239A5 - - Google Patents

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JP2024023239A5
JP2024023239A5 JP2023189768A JP2023189768A JP2024023239A5 JP 2024023239 A5 JP2024023239 A5 JP 2024023239A5 JP 2023189768 A JP2023189768 A JP 2023189768A JP 2023189768 A JP2023189768 A JP 2023189768A JP 2024023239 A5 JP2024023239 A5 JP 2024023239A5
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cas system
crispr
engineered crispr
nick
cas9 protein
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JP2023189768A
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JP2024023239A (ja
JP7682975B2 (ja
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Priority claimed from PCT/US2013/074667 external-priority patent/WO2014093622A2/en
Priority claimed from JP2020025947A external-priority patent/JP7083364B2/ja
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JP2023189768A 2013-06-17 2023-11-07 配列操作のための最適化されたＣＲＩＳＰＲ－Ｃａｓ二重ニッカーゼ系、方法および組成物 Active JP7682975B2 (ja)

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US201361836123P 2013-06-17 2013-06-17
US61/836,123 2013-06-17
US201361847537P 2013-07-17 2013-07-17
US61/847,537 2013-07-17
US201361862355P 2013-08-05 2013-08-05
US61/862,355 2013-08-05
US201361871301P 2013-08-28 2013-08-28
US61/871,301 2013-08-28
US201361915383P 2013-12-12 2013-12-12
PCT/US2013/074667 WO2014093622A2 (en) 2012-12-12 2013-12-12 Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and therapeutic applications
US61/915,383 2013-12-12
USPCT/US2013/074667 2013-12-12
JP2020025947A JP7083364B2 (ja) 2013-06-17 2020-02-19 配列操作のための最適化されたＣＲＩＳＰＲ－Ｃａｓ二重ニッカーゼ系、方法および組成物
JP2022031416A JP7383062B2 (ja) 2013-06-17 2022-03-02 配列操作のための最適化されたＣＲＩＳＰＲ－Ｃａｓ二重ニッカーゼ系、方法および組成物

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JP2024023239A JP2024023239A (ja) 2024-02-21
JP2024023239A5 true JP2024023239A5 (https=) 2024-10-03
JP7682975B2 JP7682975B2 (ja) 2025-05-26

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JP2016521450A Active JP6665088B2 (ja) 2013-06-17 2014-06-10 配列操作のための最適化されたＣＲＩＳＰＲ−Ｃａｓ二重ニッカーゼ系、方法および組成物
JP2020025947A Active JP7083364B2 (ja) 2013-06-17 2020-02-19 配列操作のための最適化されたＣＲＩＳＰＲ－Ｃａｓ二重ニッカーゼ系、方法および組成物
JP2022031416A Active JP7383062B2 (ja) 2013-06-17 2022-03-02 配列操作のための最適化されたＣＲＩＳＰＲ－Ｃａｓ二重ニッカーゼ系、方法および組成物
JP2023189768A Active JP7682975B2 (ja) 2013-06-17 2023-11-07 配列操作のための最適化されたＣＲＩＳＰＲ－Ｃａｓ二重ニッカーゼ系、方法および組成物

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JP2020025947A Active JP7083364B2 (ja) 2013-06-17 2020-02-19 配列操作のための最適化されたＣＲＩＳＰＲ－Ｃａｓ二重ニッカーゼ系、方法および組成物
JP2022031416A Active JP7383062B2 (ja) 2013-06-17 2022-03-02 配列操作のための最適化されたＣＲＩＳＰＲ－Ｃａｓ二重ニッカーゼ系、方法および組成物

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US (3) US10711285B2 (https=)
EP (2) EP3011030B1 (https=)
JP (4) JP6665088B2 (https=)
KR (1) KR20160034901A (https=)
CN (1) CN105492611A (https=)
AU (1) AU2014281027A1 (https=)
CA (1) CA2915837A1 (https=)
WO (1) WO2014204725A1 (https=)

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