|
US20030129724A1
(en)
|
2000-03-03 |
2003-07-10 |
Grozinger Christina M. |
Class II human histone deacetylases, and uses related thereto
|
|
US20040142859A1
(en)
|
2002-05-02 |
2004-07-22 |
Steffan Joan S. |
Method for treating neurodegenerative, psychiatric, and other disorders with deacetylase inhibitors
|
|
DE60227658D1
(de)
|
2001-05-02 |
2008-08-28 |
Univ California |
Verfahren zur behandlung neurodegenerativer, psychiatrischer und anderer störungen mit deacetylaseinhibitoren
|
|
US20050227915A1
(en)
|
2001-05-02 |
2005-10-13 |
Steffan Joan S |
Methods and reagents for treating neurodegenerative diseases and motor deficit disorders
|
|
EP1443928B1
(en)
|
2001-10-16 |
2011-07-27 |
Sloan-Kettering Institute For Cancer Research |
Treatment of neurodegenerative diseases and cancer of the brain
|
|
MXPA04008577A
(es)
|
2002-03-04 |
2005-07-13 |
Aton Pharma Inc |
Metodos para inducir diferenciacion terminal.
|
|
AU2003244713A1
(en)
|
2002-03-26 |
2003-10-08 |
Exonhit Therapeutics S.A. |
Histone deacetylase: novel molecular target of neurotoxicity
|
|
WO2003083067A2
(en)
|
2002-03-28 |
2003-10-09 |
Brigham And Women's Hospital, Inc. |
Histone deacetylase inhibitors for the treatment of multiple sclerosis, amyotrophic lateral sclerosis and alzheimer's disease
|
|
ITMI20040876A1
(it)
|
2004-04-30 |
2004-07-30 |
Univ Degli Studi Milano |
Inibitori delle istone deacetilasi-hdac-quali agenti ipolipidemizzati per la terapia e la prevenzione dell'arteriosclerosi e malattie cardiovascolari
|
|
US20060018921A1
(en)
|
2004-07-16 |
2006-01-26 |
Baylor College Of Medicine |
Histone deacetylase inhibitors and cognitive applications
|
|
GT200500321A
(es)
|
2004-11-09 |
2006-09-04 |
|
Compuestos y composiciones como inhibidores de proteina kinase.
|
|
CN101056632B
(zh)
*
|
2004-11-09 |
2011-12-07 |
Irm责任有限公司 |
用作蛋白激酶抑制剂的化合物和组合物
|
|
US20060135612A1
(en)
|
2004-12-17 |
2006-06-22 |
U.S. Department Of Veterans Affairs |
Method of ameliorating or abrogating the effects of a neurodegenerative disorder, such as amyotrophic lateral sclerosis (ALS), by using a HDAC inhibiting agent
|
|
SG171690A1
(en)
|
2005-03-22 |
2011-06-29 |
Harvard College |
Treatment of protein degradation disorders
|
|
CN101267779A
(zh)
|
2005-07-27 |
2008-09-17 |
福罗里达大学研究基金会有限公司 |
使用热休克治疗眼睛疾病
|
|
CA2621560A1
(en)
|
2005-09-07 |
2007-03-15 |
Braincells, Inc. |
Modulation of neurogenesis by hdac inhibition
|
|
WO2007049262A1
(en)
|
2005-10-27 |
2007-05-03 |
Berand Limited |
Methods and compositions for the promotion of neuronal growth and the treatment of asociality and affective disorders
|
|
CA2626897A1
(en)
|
2005-11-03 |
2007-05-18 |
Joshua Close |
Histone deacetylase inhibitors with aryl-pyrazolyl motifs
|
|
US20070207950A1
(en)
|
2005-12-21 |
2007-09-06 |
Duke University |
Methods and compositions for regulating HDAC6 activity
|
|
GB0612273D0
(en)
|
2006-06-21 |
2006-08-02 |
Friedrich Miescher Inst For Bi |
Prevention of muscle atrophy
|
|
US8088951B2
(en)
|
2006-11-30 |
2012-01-03 |
Massachusetts Institute Of Technology |
Epigenetic mechanisms re-establish access to long-term memory after neuronal loss
|
|
WO2008073733A1
(en)
|
2006-12-08 |
2008-06-19 |
Kalypsys, Inc. |
Salts of inhibitors of histone deacetylase for the treatment of disease
|
|
MX2009006327A
(es)
|
2006-12-15 |
2009-06-23 |
Novartis Ag |
Compuestos heterociclicos y metodos de uso de los mismos.
|
|
WO2008126932A2
(en)
|
2007-04-09 |
2008-10-23 |
Riken |
Epigenetical regulation of brain plasticity
|
|
WO2009002495A1
(en)
|
2007-06-27 |
2008-12-31 |
Merck & Co., Inc. |
4-carboxybenzylamino derivatives as histone deacetylase inhibitors
|
|
EP2195029A2
(en)
|
2007-08-24 |
2010-06-16 |
Oryzon Genomics SA |
Treatment and prevention of neurodegenerative diseases
|
|
US20090136461A1
(en)
|
2007-11-28 |
2009-05-28 |
Moon Suk Kim |
Neuronal differentiation method of adult stem cells using small molecules
|
|
AU2013203735A1
(en)
*
|
2007-12-04 |
2013-05-02 |
F. Hoffmann-La Roche Ag |
Isoxazolo-pyridine derivatives
|
|
AU2010333767A1
(en)
*
|
2009-12-22 |
2012-07-05 |
Celgene Corporation |
(Methylsulfonyl) ethyl benzene isoindoline derivatives and their therapeutical uses
|
|
KR101781663B1
(ko)
|
2010-01-13 |
2017-09-25 |
템페로 파마슈티칼즈, 인크. |
히스톤 데아세틸라제 효소를 억제하기 위한 화합물 및 이를 제조하는 방법
|
|
EP2523664A4
(en)
|
2010-01-13 |
2013-06-26 |
Tempero Pharmaceuticals Inc |
COMPOUNDS AND METHODS
|
|
WO2012018499A2
(en)
|
2010-08-05 |
2012-02-09 |
Acetylon Pharmaceuticals |
Specific regulation of cytokine levels by hdac6 inhibitors
|
|
CA2812855C
(en)
|
2010-10-08 |
2017-12-19 |
Vib Vzw |
Hdac inhibitors to treat charcot-marie-tooth disease
|
|
WO2012058128A2
(en)
|
2010-10-28 |
2012-05-03 |
Merck Sharp & Dohme Corp. |
Caprolactam mglur5 receptor modulators
|
|
WO2012118782A1
(en)
|
2011-02-28 |
2012-09-07 |
Repligen Corporation |
Histone deacetylase inhibitors
|
|
US10059723B2
(en)
|
2011-02-28 |
2018-08-28 |
Biomarin Pharmaceutical Inc. |
Histone deacetylase inhibitors
|
|
US8957066B2
(en)
*
|
2011-02-28 |
2015-02-17 |
Biomarin Pharmaceutical Inc. |
Histone deacetylase inhibitors
|
|
WO2012149540A1
(en)
|
2011-04-28 |
2012-11-01 |
The Broad Institute Inc |
Inhibitors of histone deacetylase
|
|
US20140235649A1
(en)
|
2011-05-24 |
2014-08-21 |
Lixte Biotechnology, Inc. |
Use of phosphatase inhibitors or histone deacetylase inhibitors to treat diseases characterized by loss of protein function
|
|
WO2013006408A1
(en)
|
2011-07-01 |
2013-01-10 |
Tempero Pharmaceuticals, Inc. |
Compounds and methods
|
|
EA201490228A1
(ru)
|
2011-07-08 |
2014-08-29 |
Новартис Аг |
Новые производные трифторметилоксадиазола и их применение для лечения заболевания
|
|
WO2013009830A1
(en)
|
2011-07-13 |
2013-01-17 |
Tempero Pharmaceuticals, Inc. |
Methods of treatment
|
|
WO2013009827A1
(en)
|
2011-07-13 |
2013-01-17 |
Tempero Pharmaceuticals, Inc. |
Methods of treatment
|
|
WO2013009810A1
(en)
|
2011-07-13 |
2013-01-17 |
Tempero Pharmaceuticals, Inc. |
Methods of treatment
|
|
EP2734500A4
(en)
|
2011-07-20 |
2015-04-08 |
Gen Hospital Corp |
SELECTIVE HISTONDEACETYLASE-6 INHIBITORS FOR THE TREATMENT OF BONE DISORDERS
|
|
WO2013066839A2
(en)
|
2011-10-31 |
2013-05-10 |
Glaxosmithkline Llc |
Compounds and methods
|
|
WO2013066833A1
(en)
|
2011-10-31 |
2013-05-10 |
Glaxosmithkline Llc |
Compounds and methods to inhibit histone deacetylase (hdac) enzymes
|
|
WO2013066835A2
(en)
|
2011-10-31 |
2013-05-10 |
Glaxosmithkline Llc |
Compounds and methods
|
|
WO2013066831A1
(en)
|
2011-10-31 |
2013-05-10 |
Glaxosmithkline Llc |
Compounds and methods
|
|
WO2013066838A1
(en)
|
2011-10-31 |
2013-05-10 |
Glaxosmithkline Llc |
Compounds and methods
|
|
CA2856334A1
(en)
|
2011-11-28 |
2013-06-06 |
Christina Hebach |
Novel trifluoromethyl-oxadiazole derivatives and their use in the treatment of disease
|
|
WO2013149091A1
(en)
|
2012-03-29 |
2013-10-03 |
The Regents Of The University Of Colorado, A Body Corporate |
Composition and method for treating neurodegenerative disease
|
|
US20150119327A1
(en)
|
2012-04-25 |
2015-04-30 |
The Regents Of The University Of California |
Drug screening platform for rett syndrome
|
|
US20150184154A1
(en)
|
2012-07-05 |
2015-07-02 |
Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute For Biomedical Resear |
New treatment for neurodegenerative diseases
|
|
CN104894060B
(zh)
|
2014-03-03 |
2018-11-06 |
中国科学院上海生命科学研究院 |
诱导体细胞转分化为神经干细胞的方法及其应用
|
|
TR201816176T4
(tr)
|
2014-03-12 |
2018-11-21 |
Chong Kun Dang Pharmaceutical Corp |
Histon deasetilaz 6 inhibitörleri olarak yeni bileşikler ve bunu içeren farmasötik bileşimler.
|
|
EP3187497A4
(en)
|
2014-08-26 |
2018-02-07 |
Takeda Pharmaceutical Company Limited |
Heterocyclic compound
|
|
JPWO2016039398A1
(ja)
|
2014-09-09 |
2017-06-15 |
国立大学法人大阪大学 |
含窒素複素環誘導体、神経保護剤及び癌治療用医薬組成物
|
|
TW201629026A
(zh)
|
2015-02-02 |
2016-08-16 |
佛瑪治療公司 |
作為hdac抑制劑的3-烷基雙環[4,5,0]異羥肟酸
|
|
CN107848695A
(zh)
|
2015-06-30 |
2018-03-27 |
Wm.雷格利 Jr.公司 |
用于糖果产品的包装和用于形成该包装的方法
|
|
US10357484B2
(en)
|
2015-07-17 |
2019-07-23 |
Takeda Pharmaceutical Company Limited |
Heterocyclic compound
|
|
CN108026088B
(zh)
*
|
2015-07-17 |
2021-02-12 |
武田药品工业株式会社 |
用作hdac抑制剂的噁二唑衍生物
|
|
HRP20230052T1
(hr)
|
2015-07-27 |
2023-03-03 |
Chong Kun Dang Pharmaceutical Corp. |
Spojevi derivata 1,3,4-oksadiazol sulfonamida kao inhibitori histonske deacetilaze 6, i farmaceutski pripravak koji ih sadrži
|
|
NZ739211A
(en)
|
2015-07-27 |
2019-05-31 |
Chong Kun Dang Pharmaceutical Corp |
1,3,4-oxadiazole amide derivative compound as histone deacetylase 6 inhibitor, and pharmaceutical composition containing same
|
|
BR112017027798B1
(pt)
|
2015-07-27 |
2023-12-19 |
Chong Kun Dang Pharmaceutical Corp |
Compostos de derivado de 1,3,4-oxadiazol sulfamida como inibidor de histona desacetilase 6 e a composição farmacêutica que compreende os mesmos
|
|
HRP20220003T1
(hr)
|
2015-08-04 |
2022-04-01 |
Chong Kun Dang Pharmaceutical Corp. |
Spojevi derivata 1,3,4-oksadiazola kao inhibitori histonske deacetilaze 6, i farmaceutski pripravak koji ih sadrži
|
|
WO2017033946A1
(ja)
|
2015-08-25 |
2017-03-02 |
武田薬品工業株式会社 |
複素環化合物
|
|
FI3362445T3
(fi)
|
2015-10-12 |
2023-03-21 |
Chong Kun Dang Pharmaceutical Corp |
Oksadiatsoliamiinijohdannaisyhdisteitä histonideasetylaasi 6:n inhibiittoreina ja niitä käsittävä farmaseuttinen koostumus
|
|
WO2017222952A1
(en)
*
|
2016-06-23 |
2017-12-28 |
Merck Sharp & Dohme Corp. |
3- heteroaryl substituted 5-trifluoromethyl oxadiazoles as histone deacetylase 6 (hdac6) inhibitors
|
|
US20180016314A1
(en)
|
2016-07-12 |
2018-01-18 |
Children's Hospital Medical Center |
Treatment of disease via transcription factor modulation
|
|
US10357493B2
(en)
*
|
2017-03-10 |
2019-07-23 |
Selenity Therapeutics (Bermuda), Ltd. |
Metalloenzyme inhibitor compounds
|
|
WO2018215597A1
(en)
|
2017-05-24 |
2018-11-29 |
Orphazyme A/S |
Heat shock protein inducers and frontotemporal disorders
|
|
US10435399B2
(en)
|
2017-07-31 |
2019-10-08 |
Takeda Pharmaceutical Company Limited |
HDAC6 inhibitory heterocyclic compound
|
|
WO2019032652A1
(en)
|
2017-08-09 |
2019-02-14 |
Children's Hospital Medical Center |
METHODS OF TREATING DISEASES AND NERVE INJURIES
|
|
US20200216563A1
(en)
|
2017-08-10 |
2020-07-09 |
Friedrich Miescher Institute For Biomedical Research |
Hdac6 and protein aggregation
|
|
JP6910984B2
(ja)
|
2018-03-30 |
2021-07-28 |
株式会社ホンダアクセス |
脱出ハンマー収容具
|
|
KR102316234B1
(ko)
|
2018-07-26 |
2021-10-22 |
주식회사 종근당 |
히스톤 탈아세틸화효소 6 억제제로서의 1,3,4-옥사다이아졸 유도체 화합물 및 이를 포함하는 약제학적 조성물
|
|
RS66346B1
(sr)
|
2018-10-22 |
2025-01-31 |
Alumis Inc |
Inhibitori tyk2 i njihova upotreba
|
|
EP3919055A4
(en)
|
2019-01-30 |
2022-11-09 |
Takeda Pharmaceutical Company Limited |
HETEROCYCLIC COMPOUND
|
|
CN114846012B
(zh)
*
|
2019-09-27 |
2024-01-26 |
武田药品工业株式会社 |
可用作hdac6抑制剂的2-异吲哚-1,3,4-噁二唑衍生物
|