|
US4797368A
(en)
|
1985-03-15 |
1989-01-10 |
The United States Of America As Represented By The Department Of Health And Human Services |
Adeno-associated virus as eukaryotic expression vector
|
|
US5506337A
(en)
|
1985-03-15 |
1996-04-09 |
Antivirals Inc. |
Morpholino-subunit combinatorial library and method
|
|
US5139941A
(en)
|
1985-10-31 |
1992-08-18 |
University Of Florida Research Foundation, Inc. |
AAV transduction vectors
|
|
US5010175A
(en)
|
1988-05-02 |
1991-04-23 |
The Regents Of The University Of California |
General method for producing and selecting peptides with specific properties
|
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
|
IE66205B1
(en)
|
1990-06-14 |
1995-12-13 |
Paul A Bartlett |
Polypeptide analogs
|
|
US5650489A
(en)
|
1990-07-02 |
1997-07-22 |
The Arizona Board Of Regents |
Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
|
|
US5384253A
(en)
|
1990-12-28 |
1995-01-24 |
Dekalb Genetics Corporation |
Genetic transformation of maize cells by electroporation of cells pretreated with pectin degrading enzymes
|
|
WO1993004169A1
(en)
|
1991-08-20 |
1993-03-04 |
Genpharm International, Inc. |
Gene targeting in animal cells using isogenic dna constructs
|
|
US5573905A
(en)
|
1992-03-30 |
1996-11-12 |
The Scripps Research Institute |
Encoded combinatorial chemical libraries
|
|
US5340740A
(en)
|
1992-05-15 |
1994-08-23 |
North Carolina State University |
Method of producing an avian embryonic stem cell culture and the avian embryonic stem cell culture produced by the process
|
|
US5702932A
(en)
|
1992-07-20 |
1997-12-30 |
University Of Florida |
Microinjection methods to transform arthropods with exogenous DNA
|
|
US5288514A
(en)
|
1992-09-14 |
1994-02-22 |
The Regents Of The University Of California |
Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
|
|
JPH09500534A
(ja)
|
1993-07-22 |
1997-01-21 |
メルク エンド カンパニー インコーポレーテッド |
トランスジェニック動物でのヒトインターロイキン―１βの発現
|
|
US5519134A
(en)
|
1994-01-11 |
1996-05-21 |
Isis Pharmaceuticals, Inc. |
Pyrrolidine-containing monomers and oligomers
|
|
US5593853A
(en)
|
1994-02-09 |
1997-01-14 |
Martek Corporation |
Generation and screening of synthetic drug libraries
|
|
US5539083A
(en)
|
1994-02-23 |
1996-07-23 |
Isis Pharmaceuticals, Inc. |
Peptide nucleic acid combinatorial libraries and improved methods of synthesis
|
|
US5656610A
(en)
|
1994-06-21 |
1997-08-12 |
University Of Southern California |
Producing a protein in a mammal by injection of a DNA-sequence into the tongue
|
|
US5525735A
(en)
|
1994-06-22 |
1996-06-11 |
Affymax Technologies Nv |
Methods for synthesizing diverse collections of pyrrolidine compounds
|
|
US5549974A
(en)
|
1994-06-23 |
1996-08-27 |
Affymax Technologies Nv |
Methods for the solid phase synthesis of thiazolidinones, metathiazanones, and derivatives thereof
|
|
US5736524A
(en)
|
1994-11-14 |
1998-04-07 |
Merck & Co.,. Inc. |
Polynucleotide tuberculosis vaccine
|
|
US5843780A
(en)
|
1995-01-20 |
1998-12-01 |
Wisconsin Alumni Research Foundation |
Primate embryonic stem cells
|
|
US5569588A
(en)
|
1995-08-09 |
1996-10-29 |
The Regents Of The University Of California |
Methods for drug screening
|
|
US6013516A
(en)
|
1995-10-06 |
2000-01-11 |
The Salk Institute For Biological Studies |
Vector and method of use for nucleic acid delivery to non-dividing cells
|
|
US5780448A
(en)
|
1995-11-07 |
1998-07-14 |
Ottawa Civic Hospital Loeb Research |
DNA-based vaccination of fish
|
|
GB9807935D0
(en)
|
1998-04-14 |
1998-06-10 |
Univ Edinburgh |
Lineage specific cells and progenitor cells
|
|
US5945100A
(en)
|
1996-07-31 |
1999-08-31 |
Fbp Corporation |
Tumor delivery vehicles
|
|
US5981274A
(en)
|
1996-09-18 |
1999-11-09 |
Tyrrell; D. Lorne J. |
Recombinant hepatitis virus vectors
|
|
US6090622A
(en)
|
1997-03-31 |
2000-07-18 |
The Johns Hopkins School Of Medicine |
Human embryonic pluripotent germ cells
|
|
US6087496A
(en)
|
1998-05-22 |
2000-07-11 |
G. D. Searle & Co. |
Substituted pyrazoles suitable as p38 kinase inhibitors
|
|
DE69826695T2
(de)
|
1997-05-23 |
2006-02-02 |
Bayer Pharmaceuticals Corp., West Haven |
Arylharnstoffderivate zur behandlung von inflammatorischen oder immunomodulatorischen erkrankungen
|
|
US6344476B1
(en)
|
1997-05-23 |
2002-02-05 |
Bayer Corporation |
Inhibition of p38 kinase activity by aryl ureas
|
|
US6093742A
(en)
|
1997-06-27 |
2000-07-25 |
Vertex Pharmaceuticals, Inc. |
Inhibitors of p38
|
|
US5994624A
(en)
|
1997-10-20 |
1999-11-30 |
Cotton Incorporated |
In planta method for the production of transgenic plants
|
|
BR9812944A
(pt)
|
1997-10-20 |
2000-08-08 |
Hoffmann La Roche |
Inibidores bicìclicos da cinase
|
|
WO1999027076A1
(en)
|
1997-11-25 |
1999-06-03 |
Arc Genomic Research |
Pluripotent embryonic stem cells and methods of obtaining them
|
|
US5994136A
(en)
|
1997-12-12 |
1999-11-30 |
Cell Genesys, Inc. |
Method and means for producing high titer, safe, recombinant lentivirus vectors
|
|
IL136768A0
(en)
|
1997-12-22 |
2001-06-14 |
Bayer Ag |
INHIBITION OF p38 KINASE ACTIVITY USING ARYL AND HETEROARYL SUBSTITUTED HETEROCYCLIC UREAS
|
|
WO1999032463A1
(en)
|
1997-12-22 |
1999-07-01 |
Bayer Corporation |
INHIBITION OF p38 KINASE USING SYMMETRICAL AND UNSYMMETRICAL DIPHENYL UREAS
|
|
MY132496A
(en)
|
1998-05-11 |
2007-10-31 |
Vertex Pharma |
Inhibitors of p38
|
|
JP2002521025A
(ja)
*
|
1998-07-24 |
2002-07-16 |
ザ カーネギー インスチチューション オブ ワシントン |
増殖因子のＴＧＦ−βファミリーのメンバーを使用する、生殖系列幹細胞の維持および増殖のための方法。
|
|
CA2341370A1
(en)
|
1998-08-20 |
2000-03-02 |
Smithkline Beecham Corporation |
Novel substituted triazole compounds
|
|
US6184226B1
(en)
|
1998-08-28 |
2001-02-06 |
Scios Inc. |
Quinazoline derivatives as inhibitors of P-38 α
|
|
AR023659A1
(es)
|
1998-09-18 |
2002-09-04 |
Vertex Pharma |
Un compuesto inhibidor de p38, una composicion farmaceutica que lo comprende y el uso de dicha composicion en el tratamiento y prevencion de estados patologicos
|
|
JP2002526482A
(ja)
|
1998-09-18 |
2002-08-20 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
ｐ３８のインヒビター
|
|
US6875607B1
(en)
|
1998-11-09 |
2005-04-05 |
Es Cell International Pte Ltd |
Embryonic stem cells
|
|
US6509361B1
(en)
|
1999-05-12 |
2003-01-21 |
Pharmacia Corporation |
1,5-Diaryl substituted pyrazoles as p38 kinase inhibitors
|
|
US6541477B2
(en)
|
1999-08-27 |
2003-04-01 |
Scios, Inc. |
Inhibitors of p38-a kinase
|
|
US20020142457A1
(en)
|
1999-12-28 |
2002-10-03 |
Akihiro Umezawa |
Cell having the potentiality of differentiation into cardiomyocytes
|
|
US6560871B1
(en)
|
2000-03-21 |
2003-05-13 |
Hewlett-Packard Development Company, L.P. |
Semiconductor substrate having increased facture strength and method of forming the same
|
|
US6458589B1
(en)
*
|
2000-04-27 |
2002-10-01 |
Geron Corporation |
Hepatocyte lineage cells derived from pluripotent stem cells
|
|
JP2008119003A
(ja)
*
|
2001-10-30 |
2008-05-29 |
Renomedix Institute Inc |
中胚葉幹細胞もしくはｅｓ細胞、または不死化した中胚葉幹細胞から神経系細胞への分化誘導方法
|
|
JP2005512593A
(ja)
*
|
2001-12-28 |
2005-05-12 |
セルアーティス アーベー |
多能性のヒト胚盤胞由来幹細胞株の樹立方法
|
|
GB0210539D0
(en)
*
|
2002-05-08 |
2002-06-19 |
Univ Edinburgh |
Control of es cell self renewal and lineage specification, and medium therefor
|
|
US20040219563A1
(en)
|
2002-10-16 |
2004-11-04 |
Michael West |
Method using gene trapped stem cells for making pathways of stem cell differentiation and making and isolating differentiated cells
|
|
JP2006517234A
(ja)
|
2003-02-10 |
2006-07-20 |
アムジエン・インコーポレーテツド |
バニロイド受容体リガンドおよび治療におけるこれらのリガンドの使用
|
|
AU2003901099A0
(en)
|
2003-03-11 |
2003-03-27 |
Es Cell International Pte Ltd. |
Methods of inducing differentiation of stem cells
|
|
US20070010008A1
(en)
*
|
2005-06-29 |
2007-01-11 |
Tissuetech, Inc. |
Ex vivo expansion of primary animal cells
|
|
AU2004278634B2
(en)
|
2003-10-03 |
2009-10-01 |
Keiichi Fukuda |
Method of inducing the differentiation of stem cells into cardiomyocytes
|
|
KR20070030164A
(ko)
*
|
2003-10-16 |
2007-03-15 |
더 유니버시티 코트, 더 유니버시티 오브 에딘버러 |
Ｅｓ 세포 자가 재생 및 계통 지정의 조절, 및 이를 위한배지
|
|
WO2005049812A1
(en)
|
2003-11-19 |
2005-06-02 |
Australian Stem Cell Centre Limited |
Methods for producing blood products from pluripotent cells in cell culture
|
|
US20070269412A1
(en)
|
2003-12-02 |
2007-11-22 |
Celavie Biosciences, Llc |
Pluripotent cells
|
|
JP2007528226A
(ja)
*
|
2004-03-10 |
2007-10-11 |
リージェンツ オブ ザ ユニヴァーシティ オブ カリフォルニア |
胚幹細胞の増殖用組成物および方法
|
|
EP1735430A4
(en)
*
|
2004-04-13 |
2007-10-31 |
Sungkwang Educational Foundati |
IN VITRO METHOD FOR ISOLATION, PROLIFERATION AND DIFFERENTIATION OF GERMPLE STEM CELLS
|
|
JPWO2005121320A1
(ja)
*
|
2004-06-10 |
2008-04-10 |
協和醗酵工業株式会社 |
幹細胞自己複製促進剤
|
|
US8187878B2
(en)
|
2004-08-13 |
2012-05-29 |
University Of Georgia Research Foundation, Inc. |
Methods for increasing definitive endoderm differentiation of pluripotent human embryonic stem cells with PI-3 kinase inhibitors
|
|
WO2006026473A2
(en)
|
2004-08-25 |
2006-03-09 |
University Of Georgia Research Foundation, Inc. |
METHODS AND COMPOSITIONS UTILIZING MYC AND GSK3ß TO MANIPULATE THE PLURIPOTENCY OF EMBRYONIC STEM CELLS
|
|
WO2006071608A2
(en)
|
2004-12-16 |
2006-07-06 |
President And Fellows Of Harvard College |
Histone demethylation mediated by the nuclear amine oxidase homolog lsd1
|
|
WO2006088867A2
(en)
*
|
2005-02-15 |
2006-08-24 |
Medistem Laboratories, Incorporated |
Method for expansion of stem cells
|
|
GB0505970D0
(en)
*
|
2005-03-23 |
2005-04-27 |
Univ Edinburgh |
Culture medium containing kinase inhibitor, and uses thereof
|
|
US20060234911A1
(en)
*
|
2005-03-24 |
2006-10-19 |
Hoffmann F M |
Method of reversing epithelial mesenchymal transition
|
|
US8999370B2
(en)
|
2005-05-26 |
2015-04-07 |
Thomas Jefferson University |
Method to treat and prevent posterior capsule opacification
|
|
EP1899344A1
(en)
|
2005-06-10 |
2008-03-19 |
Irm, Llc |
Compounds that maintain pluripotency of embryonic stem cells
|
|
US20080213231A1
(en)
*
|
2005-07-15 |
2008-09-04 |
Kyoto University |
Pluripotent Stem Cell Cloned From Single Cell Derived From Skeletal Muscle Tissue
|
|
CA2617611A1
(en)
|
2005-08-01 |
2007-02-08 |
Nupotential, Llc |
Production of reprogrammed cells with restored potential
|
|
WO2007021839A2
(en)
|
2005-08-10 |
2007-02-22 |
Johns Hopkins University |
Polyamines useful as anti-parasitic and anti-cancer therapeutics and as lysine-specific demethylase inhibitors
|
|
WO2007030693A2
(en)
|
2005-09-08 |
2007-03-15 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Methods for promoting stem cell proliferation and survival
|
|
KR100679642B1
(ko)
*
|
2005-11-16 |
2007-02-06 |
주식회사 알앤엘바이오 |
인간 지방조직 유래 다분화능 줄기세포 및 이를 함유하는세포치료제
|
|
US20090227032A1
(en)
|
2005-12-13 |
2009-09-10 |
Kyoto University |
Nuclear reprogramming factor and induced pluripotent stem cells
|
|
US8048999B2
(en)
*
|
2005-12-13 |
2011-11-01 |
Kyoto University |
Nuclear reprogramming factor
|
|
DE102006001640A1
(de)
|
2006-01-11 |
2007-07-12 |
Degussa Gmbh |
Keramische Wandverkleidungsverbände mit IR-Strahlung reflektierenden Eigenschaften
|
|
EP1992360A4
(en)
|
2006-02-01 |
2010-02-17 |
Univ Tokyo |
COMMON USE OF A TGF BETA SIGNAL HEMMER AND AN ANTITUMORAL AGENT
|
|
US7541186B2
(en)
|
2006-02-22 |
2009-06-02 |
University Of Washington |
Method of generating human retinal progenitors from embryonic stem cells
|
|
GB0615327D0
(en)
|
2006-03-30 |
2006-09-13 |
Univ Edinburgh |
Culture medium containing kinase inhibitors and uses thereof
|
|
JP5680850B2
(ja)
|
2006-03-30 |
2015-03-04 |
ザ・ユニバーシティ・コート・オブ・ザ・ユニバーシティ・オブ・エディンバラＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｃｏｕｒｔ ｏｆ ｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ ｏｆ Ｅｄｉｎｂｕｒｇｈ |
キナーゼインヒビターを含む培養培地およびその使用
|
|
US8741643B2
(en)
|
2006-04-28 |
2014-06-03 |
Lifescan, Inc. |
Differentiation of pluripotent stem cells to definitive endoderm lineage
|
|
SE534150C2
(sv)
*
|
2006-05-02 |
2011-05-10 |
Wisconsin Alumni Res Found |
Förfarande för differentiering av stamceller till celler av den endodermala och pankreatiska utvecklingslinjen
|
|
BRPI0713119A2
(pt)
|
2006-06-30 |
2012-04-17 |
Schering Corp |
piperidinas substituìdas que aumentam a atividade de p53 e os usos destas
|
|
GB0613756D0
(en)
*
|
2006-07-12 |
2006-08-23 |
Univ Sheffield |
Cell culture medium
|
|
PL2044056T3
(pl)
|
2006-07-14 |
2013-01-31 |
Novartis Ag |
Pochodne pirymidyny jako inhibitory ALK-5
|
|
US20080125342A1
(en)
|
2006-11-07 |
2008-05-29 |
Advanced Technology Materials, Inc. |
Formulations for cleaning memory device structures
|
|
GB0622395D0
(en)
|
2006-11-09 |
2006-12-20 |
Univ Cambridge Tech |
Methods relating to pluripotent cells
|
|
WO2008075741A1
(ja)
*
|
2006-12-20 |
2008-06-26 |
Keio University |
糖尿病治療剤及び予防剤
|
|
WO2008089351A1
(en)
|
2007-01-17 |
2008-07-24 |
Wisconsin Alumni Research Foundation |
Improved culture of stem cells
|
|
EP2128244A4
(en)
*
|
2007-01-18 |
2012-05-09 |
Riken |
PROCESS FOR INDUCTION / DIFFERENTIATION TO A PHOTOREZEPTORZELLE
|
|
WO2008088882A2
(en)
|
2007-01-19 |
2008-07-24 |
The J. David Gladstone Institutes |
Methods of generating cardiomyocytes
|
|
CA2676044C
(en)
*
|
2007-01-30 |
2019-10-22 |
University Of Georgia Research Foundation, Inc. |
Early mesoderm cells, a stable population of mesendoderm cells that has utility for generation of endoderm and mesoderm lineages and multipotent migratory cells (mmc)
|
|
US8158415B2
(en)
|
2007-02-27 |
2012-04-17 |
Procell Therapeutics Inc. |
Combined use of cell permeable Nanog and Oct4 for increasing self-renewal and suppressing differentiation of stem cells
|
|
EP2142287A4
(en)
|
2007-04-13 |
2012-05-23 |
Univ Johns Hopkins |
INHIBITORS OF LYSINPECIFIC DEMETHYLASE
|
|
US8648069B2
(en)
|
2007-06-08 |
2014-02-11 |
Abbvie Inc. |
5-substituted indazoles as kinase inhibitors
|
|
JP2008307007A
(ja)
|
2007-06-15 |
2008-12-25 |
Bayer Schering Pharma Ag |
出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞
|
|
WO2009006422A1
(en)
|
2007-06-29 |
2009-01-08 |
Stem Cell Products, Inc. |
Automated method and apparatus for embryonic stem cell culture
|
|
WO2009032456A2
(en)
|
2007-08-01 |
2009-03-12 |
Primegen Biotech Llc |
Non-viral delivery of transcription factors that reprogram human somatic cells into a stem cell-like state
|
|
ES2799897T3
(es)
|
2007-08-31 |
2020-12-22 |
Whitehead Inst Biomedical Res |
Estimulación de la vía wnt en la reprogramación de células somáticas
|
|
KR101564044B1
(ko)
|
2007-10-31 |
2015-10-28 |
고쿠리츠 다이가쿠 호진 교토 다이가쿠 |
핵초기화 방법
|
|
JP4604076B2
(ja)
|
2007-11-07 |
2010-12-22 |
国立大学法人静岡大学 |
燃料電池用電解質膜
|
|
WO2009073523A2
(en)
|
2007-11-29 |
2009-06-11 |
Children's Hospital Of Orange County |
De-differentiation of human cells
|
|
US20110190729A1
(en)
|
2007-11-30 |
2011-08-04 |
Cytomatrix Pty Ltd |
Methods of inducing pluripotency involving sox2 protein
|
|
EP2224940A1
(en)
|
2007-11-30 |
2010-09-08 |
Cytomatrix PTY LTD |
Methods of inducing pluripotency involving oct4 protein
|
|
MX2010010165A
(es)
|
2008-03-17 |
2010-11-25 |
Scripps Research Inst |
Procedimientos quimicos y geneticos combinados para generacion de celulas madre pluripotentes inducidas.
|
|
EP2315829B1
(en)
*
|
2008-08-08 |
2015-02-11 |
Mayo Foundation For Medical Education And Research |
Induced pluripotent stem cells
|
|
US8298825B1
(en)
|
2008-08-25 |
2012-10-30 |
The General Hospital Corporation |
TGF-beta receptor inhibitors to enhance direct reprogramming
|
|
US8278105B2
(en)
*
|
2008-09-09 |
2012-10-02 |
University Of Southern California |
Induction, propagation and isolation of liver progenitor cells
|
|
WO2010077955A1
(en)
|
2008-12-17 |
2010-07-08 |
The Scripps Research Institute |
Generation and maintenance of stem cells
|
|
WO2010102267A2
(en)
|
2009-03-06 |
2010-09-10 |
Ipierian, Inc. |
Tgf-beta pathway inhibitors for enhancement of cellular reprogramming of human cells
|
|
EP2438159B1
(en)
|
2009-05-29 |
2018-10-03 |
Kyoto University |
Method for selecting clone of induced pluripotent stem cells
|
|
CA2770412C
(en)
|
2009-08-07 |
2018-09-11 |
Kyoto University |
Method of efficiently establishing induced pluripotent stem cells
|
|
CA2777720C
(en)
|
2009-10-16 |
2020-10-06 |
The Scripps Research Institute |
Induction of pluripotent cells
|
|
EP2542669B1
(en)
|
2010-03-05 |
2015-01-21 |
Texas Heart Institute |
Ets2 and mesp1 generate cardiac progenitors from fibroblasts
|
|
CN102959076B
(zh)
|
2010-03-31 |
2015-09-16 |
斯克里普斯研究所 |
重编程细胞
|
|
TWI552751B
(zh)
|
2011-06-20 |
2016-10-11 |
Ｈ 朗德貝克公司 |
投予４－（（１ｒ，３ｓ）－６－氯－３－苯基－二氫茚－１－基）－１，２，２－三甲基－哌及其鹽用於治療精神分裂症的方法
|