SG11201701398SA - Resetting pluripotent stem cells - Google Patents
Resetting pluripotent stem cellsInfo
- Publication number
- SG11201701398SA SG11201701398SA SG11201701398SA SG11201701398SA SG11201701398SA SG 11201701398S A SG11201701398S A SG 11201701398SA SG 11201701398S A SG11201701398S A SG 11201701398SA SG 11201701398S A SG11201701398S A SG 11201701398SA SG 11201701398S A SG11201701398S A SG 11201701398SA
- Authority
- SG
- Singapore
- Prior art keywords
- resetting
- stem cells
- pluripotent stem
- pluripotent
- cells
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
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- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
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- C12N2500/00—Specific components of cell culture medium
- C12N2500/99—Serum-free medium
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/065—Modulators of histone acetylation
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/119—Other fibroblast growth factors, e.g. FGF-4, FGF-8, FGF-10
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/15—Transforming growth factor beta (TGF-β)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/16—Activin; Inhibin; Mullerian inhibiting substance
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/235—Leukemia inhibitory factor [LIF]
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/415—Wnt; Frizzeled
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/604—Klf-4
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/605—Nanog
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases (EC 2.)
- C12N2501/724—Glycosyltransferases (EC 2.4.)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases (EC 2.)
- C12N2501/727—Kinases (EC 2.7.)
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- C—CHEMISTRY; METALLURGY
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/73—Hydrolases (EC 3.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/90—Polysaccharides
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/999—Small molecules not provided for elsewhere
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2510/00—Genetically modified cells
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/52—Fibronectin; Laminin
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB201414992A GB201414992D0 (en) | 2014-08-22 | 2014-08-22 | Resetting human pluripotent stem cells |
GB201415368A GB201415368D0 (en) | 2014-08-29 | 2014-08-29 | Resetting pluripotent stem cells |
PCT/GB2015/052431 WO2016027099A2 (en) | 2014-08-22 | 2015-08-21 | Resetting pluripotent stem cells |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201701398SA true SG11201701398SA (en) | 2017-03-30 |
Family
ID=54011046
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201701398SA SG11201701398SA (en) | 2014-08-22 | 2015-08-21 | Resetting pluripotent stem cells |
Country Status (6)
Country | Link |
---|---|
US (1) | US10894948B2 (en) |
EP (1) | EP3183336B1 (en) |
CN (1) | CN107075472A (en) |
IL (1) | IL250689B (en) |
SG (1) | SG11201701398SA (en) |
WO (1) | WO2016027099A2 (en) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106661548B (en) | 2014-05-28 | 2020-12-11 | 儿童医院医疗中心 | Methods and systems for converting precursor cells to stomach tissue via directed differentiation |
WO2016055519A1 (en) * | 2014-10-07 | 2016-04-14 | Max-Delbrück-Centrum für Molekulare Medizin | Endogenous retrovirus transcription as a marker for primate naïve pluripotent stem cells |
EP3207123A1 (en) | 2014-10-17 | 2017-08-23 | Children's Hospital Center D/b/a Cincinnati Children's Hospital Medical Center | In vivo model of human small intestine using pluripotent stem cells and methods of making and using same |
JP6963882B2 (en) | 2016-05-05 | 2021-11-10 | チルドレンズ ホスピタル メディカル センター | Methods for the in vitro production of fundic tissue and compositions associated with such methods. |
WO2018085419A1 (en) * | 2016-11-01 | 2018-05-11 | Jian Feng | Method of producing naive pluripotent stem cells |
KR20230110839A (en) | 2016-12-05 | 2023-07-25 | 칠드런즈 호스피탈 메디칼 센터 | Colonic organoids and methods of making and using same |
WO2019151386A1 (en) | 2018-01-31 | 2019-08-08 | 富士フイルム株式会社 | Method for producing cells |
CN110423721B (en) * | 2018-05-01 | 2024-02-27 | 云南济慈再生医学研究院有限公司 | Preparation method and application of younger repair type fibroblast |
CN110423719B (en) * | 2018-05-01 | 2024-02-27 | 云南济慈再生医学研究院有限公司 | Technology for regulating Jak-Stat pathway to differentiate, dedifferentiate and rejuvenate cells and application thereof |
IT201800006076A1 (en) | 2018-06-06 | 2019-12-06 | niPSCs from somatic cells | |
US20220010283A1 (en) * | 2018-10-31 | 2022-01-13 | Kyoto University | Method for producing pluripotent stem cell having released differentiation resistance to mesendoderm |
US20220145264A1 (en) * | 2019-04-05 | 2022-05-12 | The University Of Hong Kong | Culture medium for mammalian expanded potential stem cells, composition, and methods thereof |
JP2022534395A (en) * | 2019-05-31 | 2022-07-29 | チルドレンズ ホスピタル メディカル センター | Compositions and methods for cell reprogramming |
WO2021015228A1 (en) * | 2019-07-25 | 2021-01-28 | 富士フイルム株式会社 | Method for producing specific differentiated cells |
WO2021020267A1 (en) * | 2019-07-26 | 2021-02-04 | 富士フイルム株式会社 | Medium for enhancing proliferation ability of naive type pluripotent stem cells and method for producing pluripotent stem cells |
AU2021350981A1 (en) * | 2020-09-24 | 2023-06-08 | Beijing Institute For Stem Cell And Regenerative Medicine | Activated pluripotent stem cell, and preparation method therefor and use thereof |
EP4269571A1 (en) * | 2020-12-25 | 2023-11-01 | Kyoto University | Method for producing naive human ips cells from somatic cells |
EP4029932A1 (en) | 2021-01-13 | 2022-07-20 | IMBA-Institut für Molekulare Biotechnologie GmbH | Blastocyst-like cell aggregate and methods |
EP4277978A1 (en) | 2021-01-13 | 2023-11-22 | IMBA-Institut für Molekulare Biotechnologie GmbH | Blastocyst-like cell aggregate and methods |
US20240093154A1 (en) * | 2021-02-01 | 2024-03-21 | Cedars-Sinai Medical Center | Generation of functional human ipsc-derived pancreatic islets in co-culture with isogenic ipsc-derived vascular endothelial cells |
WO2023076577A2 (en) * | 2021-10-28 | 2023-05-04 | Memorial Sloan-Kettering Cancer Center | Methods for modulating cell pluripotency and self-renewal property |
WO2023173370A1 (en) * | 2022-03-17 | 2023-09-21 | Guangzhou Institutes Of Biomedicine And Health, Chinese Academy Of Sciences | Media and methods for producing human cells and tissues from teratoma, organoids and embryoid bodies |
CN116970552A (en) * | 2022-04-22 | 2023-10-31 | 广州国家实验室 | Induction method of mammal early embryo-like cells and application thereof |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0606392D0 (en) * | 2006-03-30 | 2006-05-10 | Univ Court Of The Univeresity | Culture medium containing kinase inhibitors, and uses thereof |
JP5680850B2 (en) | 2006-03-30 | 2015-03-04 | ザ・ユニバーシティ・コート・オブ・ザ・ユニバーシティ・オブ・エディンバラThe University Court of the University of Edinburgh | Culture medium containing kinase inhibitor and use thereof |
JP2008099662A (en) * | 2006-09-22 | 2008-05-01 | Institute Of Physical & Chemical Research | Method for culturing stem cell |
KR101723144B1 (en) | 2008-12-17 | 2017-04-06 | 더 스크립스 리서치 인스티튜트 | Generation and maintenance of stem cells |
US20110088107A1 (en) * | 2009-04-24 | 2011-04-14 | Yaqub Hanna | Compositions and methods for deriving or culturing pluripotent cells |
US8193235B2 (en) * | 2009-06-12 | 2012-06-05 | University Of Kansas | Compositions and methods for establishing and maintaining stem cells in an undifferentiated state |
WO2011084747A2 (en) | 2009-12-21 | 2011-07-14 | The Johns Hopkins University | Compositions and methods for somatic tissue induced pluripotent stem cells having an endoderm origin |
WO2011130624A2 (en) * | 2010-04-16 | 2011-10-20 | Immune Disease Institute, Inc. | Sustained polypeptide expression from synthetic, modified rnas and uses thereof |
US9732319B2 (en) * | 2010-12-22 | 2017-08-15 | Fate Therapeutics, Inc. | Cell culture platform for single cell sorting and enhanced reprogramming of iPSCs |
DE102012102532A1 (en) | 2012-03-23 | 2013-09-26 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | New MSC surface markers |
CN105531365A (en) * | 2013-04-23 | 2016-04-27 | 耶达研究及发展有限公司 | Isolated naive pluripotent stem cells and methods of generating same |
WO2016016894A1 (en) | 2014-07-30 | 2016-02-04 | Yeda Research And Development Co. Ltd. | Media for culturing pluripotent stem cells |
WO2016055519A1 (en) | 2014-10-07 | 2016-04-14 | Max-Delbrück-Centrum für Molekulare Medizin | Endogenous retrovirus transcription as a marker for primate naïve pluripotent stem cells |
WO2016079146A1 (en) | 2014-11-17 | 2016-05-26 | Genome Research Limited | In vitro production of expanded potential stem cells |
JP6719449B2 (en) | 2015-03-18 | 2020-07-08 | 小野薬品工業株式会社 | Method for producing naive pluripotent stem cells |
-
2015
- 2015-08-21 US US15/505,707 patent/US10894948B2/en active Active
- 2015-08-21 EP EP15756227.3A patent/EP3183336B1/en active Active
- 2015-08-21 SG SG11201701398SA patent/SG11201701398SA/en unknown
- 2015-08-21 CN CN201580056926.5A patent/CN107075472A/en active Pending
- 2015-08-21 WO PCT/GB2015/052431 patent/WO2016027099A2/en active Application Filing
-
2017
- 2017-02-20 IL IL250689A patent/IL250689B/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
IL250689A0 (en) | 2017-04-30 |
EP3183336B1 (en) | 2020-11-25 |
CN107075472A (en) | 2017-08-18 |
US20180112187A1 (en) | 2018-04-26 |
EP3183336A2 (en) | 2017-06-28 |
US10894948B2 (en) | 2021-01-19 |
WO2016027099A2 (en) | 2016-02-25 |
IL250689B (en) | 2020-11-30 |
WO2016027099A3 (en) | 2016-04-14 |
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