JP2016127847A5 - - Google Patents

Download PDF

Info

Publication number
JP2016127847A5
JP2016127847A5 JP2016014732A JP2016014732A JP2016127847A5 JP 2016127847 A5 JP2016127847 A5 JP 2016127847A5 JP 2016014732 A JP2016014732 A JP 2016014732A JP 2016014732 A JP2016014732 A JP 2016014732A JP 2016127847 A5 JP2016127847 A5 JP 2016127847A5
Authority
JP
Japan
Prior art keywords
cells
cell
pluripotent stem
stem
marker
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2016014732A
Other languages
English (en)
Japanese (ja)
Other versions
JP6356165B2 (ja
JP2016127847A (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2016127847A publication Critical patent/JP2016127847A/ja
Publication of JP2016127847A5 publication Critical patent/JP2016127847A5/ja
Application granted granted Critical
Publication of JP6356165B2 publication Critical patent/JP6356165B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2016014732A 2009-10-30 2016-01-28 肝外胆樹からの多能性幹細胞およびそれらを単離する方法 Expired - Fee Related JP6356165B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25684609P 2009-10-30 2009-10-30
US61/256,846 2009-10-30

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2012537054A Division JP5936547B2 (ja) 2009-10-30 2010-10-28 肝外胆樹からの多能性幹細胞およびそれらを単離する方法

Publications (3)

Publication Number Publication Date
JP2016127847A JP2016127847A (ja) 2016-07-14
JP2016127847A5 true JP2016127847A5 (https=) 2016-12-01
JP6356165B2 JP6356165B2 (ja) 2018-07-11

Family

ID=43922533

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2012537054A Expired - Fee Related JP5936547B2 (ja) 2009-10-30 2010-10-28 肝外胆樹からの多能性幹細胞およびそれらを単離する方法
JP2016014732A Expired - Fee Related JP6356165B2 (ja) 2009-10-30 2016-01-28 肝外胆樹からの多能性幹細胞およびそれらを単離する方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2012537054A Expired - Fee Related JP5936547B2 (ja) 2009-10-30 2010-10-28 肝外胆樹からの多能性幹細胞およびそれらを単離する方法

Country Status (20)

Country Link
US (1) US20110135610A1 (https=)
EP (2) EP2494033B1 (https=)
JP (2) JP5936547B2 (https=)
KR (4) KR20200146043A (https=)
CN (2) CN102918145B (https=)
AR (2) AR078849A1 (https=)
AU (1) AU2016210783B2 (https=)
BR (1) BR112012009848B1 (https=)
CA (2) CA3169831C (https=)
CL (1) CL2012001117A1 (https=)
CR (1) CR20120254A (https=)
ES (1) ES2819028T3 (https=)
IL (2) IL219454A (https=)
MX (1) MX2012005087A (https=)
NZ (3) NZ622427A (https=)
PH (1) PH12012500845A1 (https=)
RU (2) RU2580246C2 (https=)
SG (2) SG10201913006XA (https=)
TW (3) TWI641688B (https=)
WO (1) WO2011053690A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3169831C (en) * 2009-10-30 2025-11-18 Sapienza Universita Di Roma Pluripodent Stem Cells from the Extrahepatic Biliary Tree and Methods for Their Isolation
WO2012178215A1 (en) * 2011-06-23 2012-12-27 The Children's Hospital Of Philadelphia Self-renewing endodermal progenitor lines generated from human pluripotent stem cells and methods of use thereof
US9533013B2 (en) 2013-03-13 2017-01-03 University Of North Carolina At Chapel Hill Method of treating pancreatic and liver conditions by endoscopic-mediated (or laparoscopic-mediated) transplantation of stem cells into/onto bile duct walls of particular regions of the biliary tree
CN103266084B (zh) * 2013-05-27 2015-03-04 刘卫辉 富集干细胞的三步分离法
KR102353589B1 (ko) * 2014-03-17 2022-01-19 에이전시 포 사이언스, 테크놀로지 앤드 리서치 핵 인자-κB 전위에 근거하여 화합물의 독성을 예측하는 방법
GB201507894D0 (en) * 2015-05-08 2015-06-24 Imagen Biotech Ltd Personalised media
GB201510950D0 (en) * 2015-06-22 2015-08-05 Cambridge Entpr Ltd In vitro Production of Cholangiocytes
WO2017072580A1 (en) * 2015-10-30 2017-05-04 Biolamina Ab Methods for producing hepatocytes
GB201521179D0 (en) 2015-12-01 2016-01-13 Univ Leuven Kath Methods for differentiating cells into hepatic stellate cells
CN105807053B (zh) * 2016-04-15 2019-04-02 苏州药明康德新药开发股份有限公司 一种肿瘤解离试剂在流式细胞检测中的应用
US10767164B2 (en) 2017-03-30 2020-09-08 The Research Foundation For The State University Of New York Microenvironments for self-assembly of islet organoids from stem cells differentiation
SG11201908905SA (en) * 2017-04-06 2019-10-30 Univ North Carolina Chapel Hill Cryopreservation method
BR112020019773A2 (pt) * 2018-03-29 2021-02-17 The University Of North Carolina At Chapel Hill células-tronco/progenitoras das glândulas duodenais de brunner, métodos de isolamento e seus usos
CN112126618B (zh) * 2019-06-24 2023-09-12 上海拜羡生物科技有限公司 一种人胆囊干细胞的获取和长期体外培养的方法
CN112111444B (zh) * 2020-08-28 2022-03-04 广东乾晖生物科技有限公司 脐带间充质干细胞重编程为肝脏细胞的方法及所制备的肝脏类器官
US20240287464A1 (en) * 2021-06-30 2024-08-29 Polbionica Sp. Z O.O. A medium for storing isolated pancreatic islets and a method for storing isolated pancreatic islets
CN115975913B (zh) * 2023-02-03 2024-06-04 北京中医药大学深圳医院(龙岗) 一种利用多能干细胞诱导分化胆囊祖细胞的方法

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3646197A (en) * 1969-05-14 1972-02-29 Zaidan Hojin Biseibutsu Novel process for removing copper from copper-containing bleomycin
US6069005A (en) 1991-08-07 2000-05-30 Albert Einstein College Of Medicine Of Yeshwa University Hapatoblasts and method of isolating same
US5660207A (en) * 1994-12-29 1997-08-26 Tylan General, Inc. Flow controller, parts of flow controller, and related method
US5861313A (en) * 1995-06-07 1999-01-19 Ontogeny, Inc. Method of isolating bile duct progenitor cells
GB9605808D0 (en) * 1996-03-20 1996-05-22 Isis Innovation CFTR gene regulator
US5830850A (en) * 1996-08-28 1998-11-03 Mount Sinai School Of Medicine Of The City Of New York Methods for the treatment of bone resorption disorders, including osteoporosis
HK1046930B (zh) * 1999-01-19 2012-08-10 查珀尔希尔北卡罗来纳大学 人肝脏祖先
US7456017B2 (en) * 1999-10-01 2008-11-25 University Of North Carolina At Chapel Hill Processes for clonal growth of hepatic progenitor cells
ATE328067T1 (de) * 2000-04-28 2006-06-15 Childrens Medical Center Isolierung von mesenchymalen stammzellen und deren verwendung
US6828145B2 (en) * 2000-05-10 2004-12-07 Cedars-Sinai Medical Center Method for the isolation of stem cells by immuno-labeling with HLA/MHC gene product marker
JP3602038B2 (ja) * 2000-07-24 2004-12-15 株式会社日立グローバルストレージテクノロジーズ 磁気ヘッドおよび磁気記録再生装置
DE10064804C2 (de) * 2000-12-22 2003-03-20 Schott Glas Alkalifreie Aluminoborosilicatgläser und ihre Verwendung
JP2005502356A (ja) 2001-09-12 2005-01-27 デヴェロゲン アクチエンゲゼルシャフト フュア エントヴィックルングスビオローギッシェ フォルシュング 治療のための腸内幹細胞の分離、培養および分化方法
US7150990B2 (en) * 2002-03-06 2006-12-19 Reprocell, Inc. Self-renewing pluripotent hepatic stem cells
PL372619A1 (en) * 2002-03-15 2005-07-25 University Of North Carolina At Chapel Hill Primitive and proximal hepatic stem cells
WO2004071464A2 (en) * 2003-02-12 2004-08-26 Johns Hopkins University School Of Medicine Diagnostic application of differentially-expressed genes in lympho-hematopoietic stem cells
DE10336152B4 (de) * 2003-08-06 2007-02-15 Nephrogen LLC, Salt Lake City Aufreinigungsverfahren für humane mesenchymale Stammzellen
US8119774B2 (en) * 2003-10-09 2012-02-21 Martin Pera Cell marker for hepatic and pancreatic stem cells and progenitor cells
EP1685237A4 (en) * 2003-10-28 2007-12-26 Caritas St Elizabeths Boston NEW MULTIPOTENTE STEM CELLS AND USE THEREOF
US7081582B2 (en) * 2004-06-30 2006-07-25 Microsoft Corporation System and method for aligning and mixing songs of arbitrary genres
JP4824036B2 (ja) 2004-12-23 2011-11-24 ヴィアサイト，インコーポレイテッド 胚体内胚葉細胞の増殖
JP4773777B2 (ja) * 2005-08-30 2011-09-14 グローバル・オーエルイーディー・テクノロジー・リミテッド・ライアビリティ・カンパニー アクティブマトリクス型表示装置
CN101310012B (zh) * 2005-10-14 2012-05-09 明尼苏达大学董事会 非胚胎干细胞分化成具有胰腺表型的细胞
JP2009515558A (ja) * 2005-11-16 2009-04-16 ユニバーシティ オブ ノース カロライナ アット チャペル ヒル 肝前駆細胞の増殖又は分化用細胞外マトリックス成分
WO2008063675A2 (en) * 2006-11-24 2008-05-29 Regents Of The University Of Minnesota Endodermal progenitor cells
CA2680254A1 (en) * 2007-03-06 2008-09-12 University Of North Carolina At Chapel Hill Complexes of hyaluronans, other matrix components, hormones and growth factors for maintenance, expansion and/or differentiation of hepatic cells
AU2008266992A1 (en) * 2007-06-15 2008-12-24 University Of North Carolina At Chapel Hill Paracrine signals from mesenchymal feeder cells and regulating expansion and differentiation of hepatic progenitors using same
JP2008307007A (ja) * 2007-06-15 2008-12-25 Bayer Schering Pharma Ag 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞
CA3114827C (en) * 2007-07-31 2023-09-05 Lifescan, Inc. Differentiation of human embryonic stem cells to pancreatic endocrine
CA3169831C (en) * 2009-10-30 2025-11-18 Sapienza Universita Di Roma Pluripodent Stem Cells from the Extrahepatic Biliary Tree and Methods for Their Isolation
US10135700B2 (en) 2014-03-10 2018-11-20 Softphone SRL Enterprise application integration on client computing devices
US10387547B2 (en) 2014-09-09 2019-08-20 Intentional Software Corporation Layout engine for creating a visual layout tree for a document

Similar Documents

Publication Publication Date Title
JP2016127847A5 (https=)
Gouon-Evans et al. BMP-4 is required for hepatic specification of mouse embryonic stem cell–derived definitive endoderm
Chen et al. Small molecule mesengenic induction of human induced pluripotent stem cells to generate mesenchymal stem/stromal cells
Hu et al. In vitro culture of isolated primary hepatocytes and stem cell-derived hepatocyte-like cells for liver regeneration
RU2016104823A (ru) Мультипотентные стволовые клетки внепечёночных желчных путей и способы их выделения
Gao et al. In vitro cultivation of islet-like cell clusters from human umbilical cord blood-derived mesenchymal stem cells
CN106754636B (zh) 体外诱导原代肝细胞胆管化并长期培养、扩增和分化的方法及其应用
EP2956538B1 (en) Bioengineered liver constructs and methods relating thereto
JP5777127B1 (ja) 原始腸内胚葉細胞及びその作製方法
US20220232820A1 (en) Cryopreservation method
Kim et al. Enhanced metabolizing activity of human ES cell-derived hepatocytes using a 3D culture system with repeated exposures to xenobiotics
CA2840192A1 (en) Self-renewing endodermal progenitor lines generated from human pluripotent stem cells and methods of use thereof
JP2010519934A (ja) 肝細胞の維持、増殖及び／又は分化のためのヒアルロナン、他のマトリックス成分、ホルモン及び増殖因子の複合体
Leibel et al. Generation of 3D whole lung organoids from induced pluripotent stem cells for modeling lung developmental biology and disease
Li et al. Coexpression of Pdx1 and betacellulin in mesenchymal stem cells could promote the differentiation of nestin-positive epithelium-like progenitors and pancreatic islet-like spheroids
US9765300B2 (en) Hepatic cell lines and stem-like cells, methods of making and using the same
Petrakova et al. Comparative analysis reveals similarities between cultured submandibular salivary gland cells and liver progenitor cells
CN111778213A (zh) 诱导分化细胞成多潜能内胚层干细胞的方法及其应用
US20200010807A1 (en) Stepwise method for inducing cholangiocyte progenitors from hepatoblasts
CN111019886B (zh) 新的干性因子和其用于培养胚胎干细胞的方法或培养体系
Subramanian et al. Scalable expansion of multipotent adult progenitor cells as three‐dimensional cell aggregates
EP4227402A1 (en) Method for inducing differentiated cells into pluripotent endoderm stem cells and application thereof
Raggi et al. Generation of complex syngeneic liver organoids from induced pluripotent stem cells to model human liver pathophysiology
Liu et al. Traditional and emerging strategies using hepatocytes for pancreatic regenerative medicine
JP2016010379A (ja) 薬物評価用細胞及び薬物評価方法