JP2021536249A5 - - Google Patents

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JP2021536249A5
JP2021536249A5 JP2021512393A JP2021512393A JP2021536249A5 JP 2021536249 A5 JP2021536249 A5 JP 2021536249A5 JP 2021512393 A JP2021512393 A JP 2021512393A JP 2021512393 A JP2021512393 A JP 2021512393A JP 2021536249 A5 JP2021536249 A5 JP 2021536249A5
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US201862727498P 2018-09-05 2018-09-05
US62/727,498 2018-09-05
US201862744073P 2018-10-10 2018-10-10
US62/744,073 2018-10-10
US201962815334P 2019-03-07 2019-03-07
US62/815,334 2019-03-07
US201962815880P 2019-03-08 2019-03-08
US62/815,880 2019-03-08
PCT/US2019/049816 WO2020051374A1 (en) 2018-09-05 2019-09-05 Allogeneic cell compositions and methods of use

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Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018329741B2 (en) * 2017-09-08 2025-02-20 Poseida Therapeutics, Inc. Compositions and methods for chimeric ligand receptor (CLR)-mediated conditional gene expression
KR20200138325A (ko) 2018-03-28 2020-12-09 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 이펙터 t 세포를 재프로그래밍하기 위한 히스톤 개질제의 용도
SG10201802979VA (en) * 2018-04-10 2019-11-28 Kah Meng Lim Immunological extract and method of production
WO2020117715A1 (en) 2018-12-03 2020-06-11 Board Of Regents, The University Of Texas System Oligo-benzamide analogs and their use in cancer treatment
KR20220004028A (ko) * 2019-04-26 2022-01-11 알로젠 테라퓨틱스 인코포레이티드 동종 car t 세포를 제조하는 방법
CN114761424B (zh) * 2019-09-05 2025-09-19 波赛达治疗公司 同种异体细胞组合物和使用方法
CA3166420A1 (en) * 2020-01-14 2021-07-22 Synthekine, Inc. Il2 orthologs and methods of use
US20230079539A1 (en) * 2020-02-10 2023-03-16 Board Of Regents, The University Of Texas System Methods for rapid cloning and expression of hla class i cells
US12540335B2 (en) 2020-03-04 2026-02-03 Poseida Therapeutics, Inc. Compositions and methods for the treatment of metabolic liver disorders
WO2021183795A1 (en) * 2020-03-11 2021-09-16 Poseida Therapeutics, Inc. Chimeric stimulatory receptors and methods of use in t cell activation and differentiation
KR20210121585A (ko) * 2020-03-30 2021-10-08 한국세라믹기술원 반응성 및 안정성 그리고 항체회수가 향상된 z-도메인 및 칼시퀘스트린 융합단백질 및 이를 이용한 항체의 분리 및 정제 방법
CN116761815A (zh) * 2020-07-29 2023-09-15 优瑞科生物技术公司 T细胞和嵌合刺激受体及其应用
CN112375138B (zh) * 2020-11-13 2022-12-13 中元汇吉生物技术股份有限公司 一种重组载脂蛋白e和应用
CN112402592B (zh) * 2020-12-04 2023-06-02 中国人民解放军陆军军医大学 Spink7蛋白在制备促进过度炎症创面愈合的药物中的应用
CN112480242B (zh) * 2020-12-04 2023-06-06 中国人民解放军陆军军医大学 Spink7蛋白在制备预防和/或治疗溃疡性结肠炎的药物中的应用
IL303712A (en) * 2020-12-18 2023-08-01 Cullinan Amber Corp Bi-functional linear fusion collagen-localized immunomodulatory molecules and methods thereofלטו
CN112941039A (zh) * 2021-02-01 2021-06-11 南京大学 一种新型类囊泡溶瘤病毒及其在制备抗肿瘤药物上的应用
WO2022192895A1 (en) * 2021-03-10 2022-09-15 H. Lee Moffitt Cancer Center And Research Institute Inc. Compositions and methods to reduce therapeutic t cell toxicity
CN113249361A (zh) * 2021-03-29 2021-08-13 南京欧凯生物科技有限公司 基质金属蛋白酶及其制备方法
KR20230171994A (ko) 2021-04-16 2023-12-21 셀진 코포레이션 선행 줄기 세포 이식을 받은 환자에서의 t 세포 요법
TWI828126B (zh) * 2021-04-27 2024-01-01 中央研究院 用以治療高三酸甘油脂血症或其相關疾病的方法
CN113481185B (zh) * 2021-08-05 2022-12-02 云南师范大学 一种耐盐β-半乳糖苷酶GalNC2-13及其制备方法和应用
CN113846070B (zh) * 2021-10-18 2023-05-16 翌圣生物科技(上海)股份有限公司 高活性的mTET2酶突变体、其编码DNA及其应用
WO2023081735A1 (en) 2021-11-03 2023-05-11 Celgene Corporation Chimeric antigen receptors specific for b-cell maturation antigen for use in treating myeloma
CN113957075B (zh) * 2021-11-22 2023-04-07 百世诺(北京)医学检验实验室有限公司 突变的遗传性心律失常基因及其应用
CN116178562A (zh) * 2021-11-29 2023-05-30 四川大学华西医院 基于efna1构建的嵌合抗原受体免疫细胞制备及其应用
CN115873902A (zh) * 2021-11-30 2023-03-31 百奥赛图(北京)医药科技股份有限公司 一种cd200和/或cd200r基因人源化的非人动物及其构建方法和应用
CN114539376B (zh) * 2022-01-17 2023-06-13 中国水产科学研究院南海水产研究所 拟穴青蟹生物标记物cyp2基因及其在制备病理检测试剂中的应用
CN114487448B (zh) * 2022-01-21 2022-10-18 天津天海新域生物科技有限公司 用于检测重症肌无力相关抗体的组合物、试剂盒及应用
JP2025504002A (ja) 2022-01-28 2025-02-06 ジュノー セラピューティクス インコーポレイテッド 細胞組成物を製造する方法
CN114113639B (zh) * 2022-01-29 2022-04-19 北京大有天弘科技有限公司 一种血型抗体检测方法及其应用
CN114137231B (zh) * 2022-01-29 2022-04-29 北京大有天弘科技有限公司 一种血型不规则抗体的检测试剂盒及其应用
WO2023151620A1 (zh) * 2022-02-09 2023-08-17 恺兴生命科技(上海)有限公司 用于细胞免疫学的组合物和方法
CN114646764B (zh) * 2022-04-08 2024-11-29 华南农业大学 一种arhgap35蛋白在猪x和y精子鉴定或分离中的应用
WO2023220655A1 (en) 2022-05-11 2023-11-16 Celgene Corporation Methods to overcome drug resistance by re-sensitizing cancer cells to treatment with a prior therapy via treatment with a t cell therapy
US20250295771A1 (en) 2022-05-11 2025-09-25 Celgene Corporation Methods and uses related to t cell therapy and production of same
CN114958862B (zh) * 2022-05-23 2023-12-08 郑州伊美诺生物技术有限公司 检测慢性间质性肾炎的重组抗原的制备方法
WO2023230548A1 (en) 2022-05-25 2023-11-30 Celgene Corporation Method for predicting response to a t cell therapy
EP4532695A1 (en) 2022-05-25 2025-04-09 Celgene Corporation Methods of manufacturing t cell therapies
CN114920816B (zh) * 2022-06-06 2024-04-05 孙英贤 Baf155突变基因及其制药用途
CN114989287B (zh) * 2022-06-06 2024-04-09 孙英贤 脱乙酰化修饰的baf155蛋白及其制药用途
WO2024023245A1 (en) * 2022-07-27 2024-02-01 Biocell Innovations Pte. Ltd. Production of cells and viral vectors
CN115747170B (zh) * 2022-08-29 2023-08-04 四川大学 一种豇豆褪绿斑驳病毒-多肽复合物及其在骨质疏松治疗中的应用
CN115820580A (zh) * 2022-08-31 2023-03-21 武汉爱博泰克生物科技有限公司 活性重组hTET2蛋白的表达及纯化方法
CN115558712B (zh) * 2022-09-22 2026-03-24 华中科技大学同济医学院附属协和医院 Fam177a1的新用途
CN115850512B (zh) * 2022-10-14 2025-11-07 江苏大学 一种用于靶向治疗肿瘤的重组融合蛋白及其制备方法
WO2024097905A1 (en) 2022-11-02 2024-05-10 Celgene Corporation Methods of treatment with t cell therapy and immunomodulatory agent maintenance therapy
CN115976004B (zh) * 2022-12-27 2024-07-09 天津科技大学 一种黄体酮17α-羟化酶突变体及其应用
JP2026503550A (ja) 2023-01-20 2026-01-29 ポセイダ セラピューティクス,インコーポレイティド リピドイド化合物ならびに関連する組成物および使用
GB2626983A (en) * 2023-02-10 2024-08-14 Quell Therapeutics Ltd Protein
WO2024168192A1 (en) 2023-02-10 2024-08-15 Celgene Corporation Assessment of bcma in biological samples
CN116253778B (zh) * 2023-03-03 2025-09-23 中山大学 一种缓解长春新碱致神经病理性疼痛的多肽及其应用
CN118109416B (zh) * 2023-03-30 2024-11-22 广州百吉生物制药有限公司 功能增强型工程化免疫细胞及其制备和应用
KR20250173518A (ko) 2023-04-05 2025-12-10 포세이다 테라퓨틱스, 인크. 트랜스포사제 폴리뉴클레오티드 및 그의 용도
CN121219409A (zh) 2023-04-05 2025-12-26 波西达治疗公司 转座酶及其用途
KR20250167671A (ko) 2023-04-05 2025-12-01 포세이다 테라퓨틱스, 인크. 키메라 트랜스포사제 및 그의 용도
CN116478271B (zh) * 2023-06-19 2023-08-29 青岛大学 半滑舌鳎抗病基因PPARα及其编码蛋白的应用
CN119320771A (zh) * 2023-07-17 2025-01-17 北京艺妙神州医药科技有限公司 用于敲除t细胞中的trac和b2m的试剂和方法
CN116948015B (zh) * 2023-07-18 2024-07-05 山西锦波生物医药股份有限公司 生物合成人体结构性材料xxii型胶原蛋白的方法
WO2025029930A1 (en) * 2023-07-31 2025-02-06 Legend Biotech Ireland Limited Cells overexpressing cd31 and methods of use thereof
CN116854801A (zh) * 2023-08-21 2023-10-10 广东省人民医院 Hand1重组蛋白及其制备方法和在治疗扩张性心肌病药物中的应用
WO2025049925A2 (en) 2023-09-01 2025-03-06 Poseida Therapeutics, Inc. Lipidoid compounds and related compositions and uses
WO2025055927A1 (en) * 2023-09-13 2025-03-20 Qihan Hong Kong Limited Immunotherapies using hypoimmunogenic engineered cells
WO2025064507A1 (en) 2023-09-19 2025-03-27 Poseida Therapeutics, Inc. Compositions and methods for integration of viral vectors
CN117586418B (zh) * 2023-11-08 2025-07-15 东南大学 一种丝氨酸蛋白酶抑制剂及其应用
WO2025106376A1 (en) * 2023-11-17 2025-05-22 Dna Twopointo Inc. Mammalian cell lines for transient protein production
CN117551621B (zh) * 2023-11-20 2024-04-30 梅州市人民医院(梅州市医学科学院) 一种杂交瘤细胞株l008、单克隆抗体及其应用
CN117883382B (zh) * 2023-11-27 2025-02-14 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) 高效递送疫苗的脂质体载体及脂质体疫苗的制备与用途
CN117820434B (zh) * 2023-12-31 2024-11-19 武汉优恩生物科技有限公司 牛羊妊娠相关糖蛋白的多肽抗原及应用
WO2025156492A1 (zh) * 2024-01-23 2025-07-31 星尘股份有限公司 转座酶及其用途
WO2025160432A1 (en) 2024-01-26 2025-07-31 Poseida Therapeutics, Inc. Methods and compositions for enhancing in vivo persistence and potency of cell therapy
CN118146342A (zh) * 2024-02-06 2024-06-07 同济大学 一种Smad5突变体及在防治糖尿病中的应用
CN117919389B (zh) * 2024-03-22 2024-07-23 上海南方模式生物科技股份有限公司 肿瘤新抗原dna疫苗
CN118584109B (zh) * 2024-03-26 2025-08-15 首都医科大学附属北京胸科医院 一种筛选耐药性肺癌的生物标志物
WO2025221789A1 (en) 2024-04-16 2025-10-23 Poseida Therapeutics, Inc. Compositions and methods for use in car/tcr cell therapies
CN118308420B (zh) * 2024-04-19 2025-06-03 东北农业大学 一种大豆基因Glyma.18G041900的应用
CN118360271B (zh) * 2024-05-07 2025-12-05 中国海洋大学 一种脂肪酶突变体及其在提升白酒酯类风味物质中的应用
CN118240829B (zh) * 2024-05-21 2024-07-23 华南农业大学 NompC基因在防治桔小实蝇中的应用
WO2026080393A1 (en) 2024-10-07 2026-04-16 Poseida Therapeutics, Inc. Compositions and methods for use in car cell therapies
CN119736407A (zh) * 2024-12-27 2025-04-01 西北农林科技大学 一种提高动物生长速度和大小的stc2基因编码序列突变体的应用
CN119899820B (zh) * 2025-01-23 2026-04-03 深圳开悦生命科技有限公司 Dhx8融合蛋白及其制备方法
CN120209114B (zh) * 2025-03-07 2026-04-07 首都医科大学 一种含有penk蛋白的组合物及其应用
CN119874865B (zh) * 2025-03-11 2025-11-25 东北林业大学 一种溪荪ost48蛋白在植物促分蘖中的应用
CN120192430B (zh) * 2025-03-24 2025-08-22 安康市中心医院 一种基于硒修饰的心肌保护多肽及其制备方法与应用
CN119978086B (zh) * 2025-03-31 2025-10-17 中国农业大学 一种调控植物生长发育的蛋白质dap1及其编码基因和应用
CN120607598B (zh) * 2025-05-16 2026-02-27 安徽大学 人源先锋转录因子sox15 hmg结构域重组蛋白及其制备方法
CN120624647B (zh) * 2025-05-30 2026-04-03 山西省肿瘤医院 鼻咽癌诊断或预测的甲基化标志物组合及应用、试剂盒和计算机可读存储介质
CN120591344B (zh) * 2025-06-13 2026-04-03 广州景旸生物科技有限公司 Col3a1蛋白的制备方法及其应用
CN121203036A (zh) * 2025-09-24 2025-12-26 北京多美康医药科技有限公司 一种重组型胶原蛋白iii+x及其制备方法和应用
CN121186348B (zh) * 2025-11-25 2026-02-24 北京大学人民医院 瓜氨酸化内凝集素-1多肽在制备类风湿关节炎诊断产品中的应用
CN121471381A (zh) * 2026-01-12 2026-02-06 南京医科大学 Tat-po1及其在治疗神经退行性疾病肌萎缩侧索硬化症中的应用
CN121538143B (zh) * 2026-01-20 2026-04-10 北京绿色康成生物技术有限公司 生产麦角硫因的重组微生物、重组表达载体及制备麦角硫因的方法

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4656134A (en) 1982-01-11 1987-04-07 Board Of Trustees Of Leland Stanford Jr. University Gene amplification in eukaryotic cells
US5168062A (en) 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4766067A (en) 1985-05-31 1988-08-23 President And Fellows Of Harvard College Gene amplification
GB8601597D0 (en) 1986-01-23 1986-02-26 Wilson R H Nucleotide sequences
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US4889818A (en) 1986-08-22 1989-12-26 Cetus Corporation Purified thermostable enzyme
US4921794A (en) 1987-01-14 1990-05-01 President And Fellows Of Harvard College T7 DNA polymerase
US4795699A (en) 1987-01-14 1989-01-03 President And Fellows Of Harvard College T7 DNA polymerase
US5130238A (en) 1988-06-24 1992-07-14 Cangene Corporation Enhanced nucleic acid amplification process
US5142033A (en) 1988-09-23 1992-08-25 Hoffmann-La Roche Inc. Structure-independent DNA amplification by the polymerase chain reaction
US5091310A (en) 1988-09-23 1992-02-25 Cetus Corporation Structure-independent dna amplification by the polymerase chain reaction
US5066584A (en) 1988-09-23 1991-11-19 Cetus Corporation Methods for generating single stranded dna by the polymerase chain reaction
US4994370A (en) 1989-01-03 1991-02-19 The United States Of America As Represented By The Department Of Health And Human Services DNA amplification technique
US5266491A (en) 1989-03-14 1993-11-30 Mochida Pharmaceutical Co., Ltd. DNA fragment and expression plasmid containing the DNA fragment
US5580734A (en) 1990-07-13 1996-12-03 Transkaryotic Therapies, Inc. Method of producing a physical map contigous DNA sequences
US5641670A (en) 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
US5733761A (en) 1991-11-05 1998-03-31 Transkaryotic Therapies, Inc. Protein production and protein delivery
US5712149A (en) * 1995-02-03 1998-01-27 Cell Genesys, Inc. Chimeric receptor molecules for delivery of co-stimulatory signals
EP3783098A1 (en) * 2013-05-14 2021-02-24 Board Of Regents, The University Of Texas System Human application of engineered chimeric antigen receptor (car) t-cells
TWI750110B (zh) * 2014-07-21 2021-12-21 瑞士商諾華公司 使用人類化抗-bcma嵌合抗原受體治療癌症
GB201415347D0 (en) * 2014-08-29 2014-10-15 Ucl Business Plc Signalling system
US10888608B2 (en) * 2014-09-02 2021-01-12 Bellicum Pharmaceuticals, Inc. Costimulation of chimeric antigen receptors by MyD88 and CD40 polypeptides
EP4706777A2 (en) * 2016-04-15 2026-03-11 Alpine Immune Sciences, Inc. Cd80 variant immunomodulatory proteins and uses thereof
JP7114490B2 (ja) * 2016-06-24 2022-08-08 アイセル・ジーン・セラピューティクス・エルエルシー キメラ抗体受容体(CARs)の構成およびその使用方法
AU2018236461B2 (en) * 2017-03-17 2025-03-27 Fred Hutchinson Cancer Center Immunomodulatory fusion proteins and uses thereof
CA3071683A1 (en) * 2017-08-08 2019-02-14 Sangamo Therapeutics, Inc. Chimeric antigen receptor mediated cell targeting
KR102849343B1 (ko) * 2018-03-07 2025-08-25 포세이다 테라퓨틱스, 인크. Cartyrin 조성물 및 사용 방법

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