JP2021522790A5 - - Google Patents
Info
- Publication number
- JP2021522790A5 JP2021522790A5 JP2020561076A JP2020561076A JP2021522790A5 JP 2021522790 A5 JP2021522790 A5 JP 2021522790A5 JP 2020561076 A JP2020561076 A JP 2020561076A JP 2020561076 A JP2020561076 A JP 2020561076A JP 2021522790 A5 JP2021522790 A5 JP 2021522790A5
- Authority
- JP
- Japan
- Prior art keywords
- domain
- type
- lectin
- caar
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024027975A JP2024059867A (ja) | 2018-05-02 | 2024-02-28 | ホスホリパーゼａ２受容体キメラ自己受容体ｔ細胞の組成物および方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862665863P | 2018-05-02 | 2018-05-02 | |
| US62/665,863 | 2018-05-02 | ||
| PCT/US2019/030459 WO2019213434A1 (en) | 2018-05-02 | 2019-05-02 | Compositions and methods of phospholipase a2 receptor chimeric autoantibody receptor t cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024027975A Division JP2024059867A (ja) | 2018-05-02 | 2024-02-28 | ホスホリパーゼａ２受容体キメラ自己受容体ｔ細胞の組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021522790A JP2021522790A (ja) | 2021-09-02 |
| JP2021522790A5 true JP2021522790A5 (https=) | 2022-05-13 |
| JP7519906B2 JP7519906B2 (ja) | 2024-07-22 |
Family
ID=68386834
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020561076A Active JP7519906B2 (ja) | 2018-05-02 | 2019-05-02 | ホスホリパーゼａ２受容体キメラ自己受容体ｔ細胞の組成物および方法 |
| JP2024027975A Pending JP2024059867A (ja) | 2018-05-02 | 2024-02-28 | ホスホリパーゼａ２受容体キメラ自己受容体ｔ細胞の組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024027975A Pending JP2024059867A (ja) | 2018-05-02 | 2024-02-28 | ホスホリパーゼａ２受容体キメラ自己受容体ｔ細胞の組成物および方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US20210095001A1 (https=) |
| EP (1) | EP3813885A4 (https=) |
| JP (2) | JP7519906B2 (https=) |
| KR (1) | KR20210007998A (https=) |
| CN (1) | CN112312930A (https=) |
| AU (1) | AU2019262131A1 (https=) |
| CA (1) | CA3098865A1 (https=) |
| MX (1) | MX2020011610A (https=) |
| WO (1) | WO2019213434A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20170151281A1 (en) | 2015-02-19 | 2017-06-01 | Batu Biologics, Inc. | Chimeric antigen receptor dendritic cell (car-dc) for treatment of cancer |
| US10980836B1 (en) | 2019-12-11 | 2021-04-20 | Myeloid Therapeutics, Inc. | Therapeutic cell compositions and methods of manufacturing and use thereof |
| CN113527507A (zh) * | 2020-04-16 | 2021-10-22 | 上海赛比曼生物科技有限公司 | 靶向cd22的嵌合抗原受体及其制法和应用 |
| EP4240367A4 (en) | 2020-11-04 | 2024-10-16 | Myeloid Therapeutics, Inc. | MODIFIED CHIMERIC FUSION PROTEIN COMPOSITIONS AND METHODS OF USE THEREOF |
| WO2022136503A1 (en) | 2020-12-22 | 2022-06-30 | Deutsches Zentrum Für Neurodegenerative Erkrankungen E. V. (Dzne) | Chimeric autoantibody receptor (caar) comprising a nicotinic acetylcholine receptor autoantigen |
| WO2022197949A2 (en) | 2021-03-17 | 2022-09-22 | Myeloid Therapeutics, Inc. | Engineered chimeric fusion protein compositions and methods of use thereof |
| EP4083061A1 (en) * | 2021-04-30 | 2022-11-02 | Kilometro Rosso SPA | Fusion proteins and use thereof in the treatment of membranous nephropathy |
| BR112023023642A2 (pt) | 2021-05-11 | 2024-01-30 | Myeloid Therapeutics Inc | Métodos e composições para integração genômica |
| EP4380963A4 (en) * | 2021-08-05 | 2025-06-04 | The Trustees of The University of Pennsylvania | Compositions and methods of chimeric autoantibody receptor cells expressing extended phospholipase a2 receptor fragments |
| JP2024545870A (ja) * | 2021-12-15 | 2024-12-13 | シャンハイ シンヴィダ バイオテクノロジー カンパニー リミテッド | 血小板減少症を治療するための製品及び方法 |
| CN114588881B (zh) * | 2022-03-07 | 2023-07-18 | 大连理工大学 | 免疫吸附剂及其制备方法 |
| CN116082517B (zh) * | 2022-05-26 | 2025-08-22 | 成都地奥制药集团有限公司 | 融合蛋白及其用途 |
| KR20250057777A (ko) | 2022-07-25 | 2025-04-29 | 인테리우스 바이오테라퓨틱스, 인코포레이티드 | 돌연변이된 폴리펩티드, 이를 포함하는 조성물, 및 그 용도(mutated polypeptides, compositions comprising the same, and uses thereof) |
| CN115838751A (zh) * | 2022-11-22 | 2023-03-24 | 迪亚莱博（张家港）生物科技有限公司 | 一种磷脂酶a2受体重组蛋白的制备方法 |
| CN121941504A (zh) * | 2023-08-01 | 2026-04-28 | 梅里达生物科学公司 | 用于控制自身免疫反应的分子 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR901228A (fr) | 1943-01-16 | 1945-07-20 | Deutsche Edelstahlwerke Ag | Système d'aimant à entrefer annulaire |
| US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
| US6534055B1 (en) | 1988-11-23 | 2003-03-18 | Genetics Institute, Inc. | Methods for selectively stimulating proliferation of T cells |
| US6905680B2 (en) | 1988-11-23 | 2005-06-14 | Genetics Institute, Inc. | Methods of treating HIV infected subjects |
| US5858358A (en) | 1992-04-07 | 1999-01-12 | The United States Of America As Represented By The Secretary Of The Navy | Methods for selectively stimulating proliferation of T cells |
| US5585362A (en) | 1989-08-22 | 1996-12-17 | The Regents Of The University Of Michigan | Adenovirus vectors for gene therapy |
| US5199942A (en) | 1991-06-07 | 1993-04-06 | Immunex Corporation | Method for improving autologous transplantation |
| GB9125768D0 (en) | 1991-12-04 | 1992-02-05 | Hale Geoffrey | Therapeutic method |
| US5350674A (en) | 1992-09-04 | 1994-09-27 | Becton, Dickinson And Company | Intrinsic factor - horse peroxidase conjugates and a method for increasing the stability thereof |
| US7175843B2 (en) | 1994-06-03 | 2007-02-13 | Genetics Institute, Llc | Methods for selectively stimulating proliferation of T cells |
| US6692964B1 (en) | 1995-05-04 | 2004-02-17 | The United States Of America As Represented By The Secretary Of The Navy | Methods for transfecting T cells |
| US7067318B2 (en) | 1995-06-07 | 2006-06-27 | The Regents Of The University Of Michigan | Methods for transfecting T cells |
| ZA973051B (en) | 1996-04-24 | 1998-10-12 | Genentech Inc | Type c lectins |
| HK1047109A1 (zh) | 1999-10-15 | 2003-02-07 | University Of Massachusetts | 作为指定基因干预工具的rna干预轨迹基因 |
| US6326193B1 (en) | 1999-11-05 | 2001-12-04 | Cambria Biosciences, Llc | Insect control agent |
| KR20030032922A (ko) | 2000-02-24 | 2003-04-26 | 싸이트 테라피스 인코포레이티드 | 세포의 동시 자극 및 농축 |
| US7572631B2 (en) | 2000-02-24 | 2009-08-11 | Invitrogen Corporation | Activation and expansion of T cells |
| US6867041B2 (en) | 2000-02-24 | 2005-03-15 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
| US6797514B2 (en) | 2000-02-24 | 2004-09-28 | Xcyte Therapies, Inc. | Simultaneous stimulation and concentration of cells |
| AU2001275474A1 (en) | 2000-06-12 | 2001-12-24 | Akkadix Corporation | Materials and methods for the control of nematodes |
| US7745140B2 (en) | 2002-01-03 | 2010-06-29 | The Trustees Of The University Of Pennsylvania | Activation and expansion of T-cells using an engineered multivalent signaling platform as a research tool |
| WO2005118788A2 (en) | 2004-05-27 | 2005-12-15 | The Trustees Of The University Of Pennsylvania | Novel artificial antigen presenting cells and uses therefor |
| JP2011526916A (ja) * | 2008-06-30 | 2011-10-20 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 全身性紅斑性狼瘡を同定および処置するための診断標的および治療標的としてのリソソームホスホリパーゼａ２（ｌｐｌａ２）活性 |
| PH12013501201A1 (en) * | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| US20140155470A1 (en) * | 2011-07-08 | 2014-06-05 | David Bernard | Pla2r1 as anti-tumoral compound and as biomarker for the detection of cancer |
| WO2013044225A1 (en) * | 2011-09-22 | 2013-03-28 | The Trustees Of The University Of Pennsylvania | A universal immune receptor expressed by t cells for the targeting of diverse and multiple antigens |
| WO2013151665A2 (en) * | 2012-04-02 | 2013-10-10 | modeRNA Therapeutics | Modified polynucleotides for the production of proteins associated with human disease |
| CN113604491A (zh) * | 2014-05-02 | 2021-11-05 | 宾夕法尼亚大学董事会 | 嵌合自身抗体受体t细胞的组合物和方法 |
| CN108027367A (zh) * | 2015-07-10 | 2018-05-11 | 楚尼斯 | 基于pla2r1表位谱和扩散分析的膜性肾病的预后和监测 |
| CN109891245B (zh) * | 2016-08-12 | 2023-05-05 | 美国创新免疫科技有限公司 | 自身免疫疾病的诊断、预防和/或治疗 |
| WO2018127585A1 (en) | 2017-01-06 | 2018-07-12 | Txcell | Monospecific regulatory t cell population with cytotoxicity for b cells |
| CN107663235B (zh) * | 2017-08-11 | 2018-05-22 | 南京诺唯赞医疗科技有限公司 | 特发性膜性肾病相关的pla2r重组蛋白及其应用 |
-
2019
- 2019-05-02 CN CN201980042269.7A patent/CN112312930A/zh active Pending
- 2019-05-02 JP JP2020561076A patent/JP7519906B2/ja active Active
- 2019-05-02 AU AU2019262131A patent/AU2019262131A1/en not_active Abandoned
- 2019-05-02 KR KR1020207033822A patent/KR20210007998A/ko not_active Ceased
- 2019-05-02 MX MX2020011610A patent/MX2020011610A/es unknown
- 2019-05-02 WO PCT/US2019/030459 patent/WO2019213434A1/en not_active Ceased
- 2019-05-02 US US17/051,248 patent/US20210095001A1/en not_active Abandoned
- 2019-05-02 EP EP19796773.0A patent/EP3813885A4/en active Pending
- 2019-05-02 CA CA3098865A patent/CA3098865A1/en active Pending
-
2021
- 2021-12-06 US US17/543,429 patent/US11884716B2/en active Active
-
2024
- 2024-02-28 JP JP2024027975A patent/JP2024059867A/ja active Pending
- 2024-04-19 US US18/640,092 patent/US20240383965A1/en active Pending
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