JP2021526795A5 - - Google Patents

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Publication number
JP2021526795A5
JP2021526795A5 JP2020567760A JP2020567760A JP2021526795A5 JP 2021526795 A5 JP2021526795 A5 JP 2021526795A5 JP 2020567760 A JP2020567760 A JP 2020567760A JP 2020567760 A JP2020567760 A JP 2020567760A JP 2021526795 A5 JP2021526795 A5 JP 2021526795A5
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JP
Japan
Prior art keywords
caar
domain
cells
seq
acid sequence
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JP2020567760A
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English (en)
Japanese (ja)
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JPWO2019236593A5 (https=
JP7561036B2 (ja
JP2021526795A (ja
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Priority claimed from PCT/US2019/035409 external-priority patent/WO2019236593A1/en
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Publication of JP2021526795A5 publication Critical patent/JP2021526795A5/ja
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JP2020567760A 2018-06-05 2019-06-04 筋特異的キナーゼキメラ自己受容体細胞の組成物および方法 Active JP7561036B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862680769P 2018-06-05 2018-06-05
US62/680,769 2018-06-05
PCT/US2019/035409 WO2019236593A1 (en) 2018-06-05 2019-06-04 Compositions and methods of muscle specific kinase chimeric autoantibody receptor cells

Publications (4)

Publication Number Publication Date
JP2021526795A JP2021526795A (ja) 2021-10-11
JPWO2019236593A5 JPWO2019236593A5 (https=) 2022-06-08
JP2021526795A5 true JP2021526795A5 (https=) 2022-06-08
JP7561036B2 JP7561036B2 (ja) 2024-10-03

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JP2020567760A Active JP7561036B2 (ja) 2018-06-05 2019-06-04 筋特異的キナーゼキメラ自己受容体細胞の組成物および方法

Country Status (9)

Country Link
US (2) US11905321B2 (https=)
EP (1) EP3801642A4 (https=)
JP (1) JP7561036B2 (https=)
KR (1) KR20210018833A (https=)
CN (1) CN112423793A (https=)
AU (1) AU2019282634A1 (https=)
CA (1) CA3101028A1 (https=)
MX (1) MX421685B (https=)
WO (1) WO2019236593A1 (https=)

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US20220298221A1 (en) * 2019-06-05 2022-09-22 Deutsches Zentrum Für Neurodegenerative Erkrankungen E. V. (Dzne) Chimeric autoantibody receptor (caar) that binds autoantibodies targeting the central nervous system in neurological autoimmune disease
CN114075568A (zh) * 2020-08-18 2022-02-22 苏州博腾生物制药有限公司 靶向烟碱乙酰胆碱受体自身抗体的组合物和方法
WO2022136503A1 (en) 2020-12-22 2022-06-30 Deutsches Zentrum Für Neurodegenerative Erkrankungen E. V. (Dzne) Chimeric autoantibody receptor (caar) comprising a nicotinic acetylcholine receptor autoantigen
US20250049849A1 (en) * 2021-12-15 2025-02-13 Shanghai Synvida Biotechnology Co. Ltd. Product and method for treating thrombocytopenia
WO2024059704A1 (en) * 2022-09-14 2024-03-21 The Johns Hopkins University Compositions of chimeric autoantigen-t cell receptor (catcr)-t cells and methods of making and using the same
JP2025541179A (ja) * 2022-12-08 2025-12-18 ザ・ジョンズ・ホプキンス・ユニバーシティ 二重特異性自己抗原-免疫エフェクター細胞誘導抗体およびその使用
WO2025072450A1 (en) 2023-09-26 2025-04-03 Werewolf Therapeutics, Inc. Enhanced adoptive cell therapy
CN119265218A (zh) * 2023-11-24 2025-01-07 福建医科大学附属第二医院 一种MuSK抗体检测方法及相应产品
WO2025199276A1 (en) * 2024-03-20 2025-09-25 Cabaletta Bio, Inc. Methods and compositions for treating autoimmune diseases

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US5858358A (en) 1992-04-07 1999-01-12 The United States Of America As Represented By The Secretary Of The Navy Methods for selectively stimulating proliferation of T cells
US6352694B1 (en) 1994-06-03 2002-03-05 Genetics Institute, Inc. Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells
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WO2015039015A2 (en) * 2013-09-13 2015-03-19 New York University Methods for treating muscle specific receptor kinase myasthenia gravis
DK3166968T3 (da) * 2014-05-02 2021-12-06 Univ Pennsylvania Sammensætninger og fremgangsmåder til kimæriske autoantistofreceptor-T-celler
TWI750110B (zh) * 2014-07-21 2021-12-21 瑞士商諾華公司 使用人類化抗-bcma嵌合抗原受體治療癌症
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