|
US5510362A
(en)
|
1992-03-13 |
1996-04-23 |
Merck, Sharp And Dohme Limited |
Imidazole, triazole and tetrazole derivatives
|
|
GB9207396D0
(en)
|
1992-04-03 |
1992-05-13 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5952294A
(en)
|
1996-07-31 |
1999-09-14 |
University Of Pittsburgh Of The Commonwealth System Of Higher Education |
Peptidyl prodrugs and methods of making and using the same
|
|
BR0210149A
(pt)
|
2001-05-09 |
2004-06-29 |
Newbiotics Inc |
Pródrogas ativadas por deformilase de peptìdeo
|
|
US6642390B2
(en)
|
2001-07-11 |
2003-11-04 |
Lexicon Pharmaceuticals, Inc. |
One step synthesis of 1,2,3-triazole carboxylic acids
|
|
EP1458708B1
(en)
|
2001-12-18 |
2007-09-26 |
Merck & Co., Inc. |
Heteroaryl substituted triazole modulators of metabotropic glutamate receptor-5
|
|
MXPA04010550A
(es)
|
2002-04-26 |
2005-01-25 |
Pfizer Prod Inc |
Inhibidores de metaloproteinasa de pirimidina-2,4,6-triona.
|
|
US7354938B2
(en)
*
|
2004-03-23 |
2008-04-08 |
Amgen Inc. |
Pyrazole compounds and uses related thereto
|
|
TWI309240B
(en)
|
2004-09-17 |
2009-05-01 |
Hoffmann La Roche |
Anti-ox40l antibodies
|
|
CN101384183B
(zh)
|
2005-02-04 |
2012-07-04 |
西诺米克斯公司 |
包含连接有杂芳基部分的化合物及其作为用于食物组合物的新型鲜味调节剂、促味剂和味觉增强剂的应用
|
|
WO2006091898A2
(en)
*
|
2005-02-25 |
2006-08-31 |
Adenosine Therapeutics, Llc |
Pyrazolyl substituted xanthines
|
|
JP5238936B2
(ja)
|
2005-03-25 |
2013-07-17 |
ジーアイティーアール,インク. |
Gitr結合分子およびその使用
|
|
KR101704734B1
(ko)
|
2005-07-01 |
2017-02-09 |
이. 알. 스퀴부 앤드 선즈, 엘.엘.씨. |
예정 사멸 리간드 1 (피디-엘1)에 대한 인간 모노클로날 항체
|
|
CA2646333C
(en)
*
|
2006-03-17 |
2014-06-17 |
Cv Therapeutics, Inc. |
Method of preventing and treating hepatic disease using a2b adenosine receptor antagonists
|
|
CN101511815A
(zh)
|
2006-07-04 |
2009-08-19 |
阿斯利康(瑞典)有限公司 |
新型吡啶类似物
|
|
US7994321B2
(en)
|
2006-08-08 |
2011-08-09 |
Hoffmann-La Roche Inc. |
Substituted thieno[3,2-C]pyridine-7-carboxylic acid derivatives
|
|
EP1987839A1
(en)
|
2007-04-30 |
2008-11-05 |
I.N.S.E.R.M. Institut National de la Sante et de la Recherche Medicale |
Cytotoxic anti-LAG-3 monoclonal antibody and its use in the treatment or prevention of organ transplant rejection and autoimmune disease
|
|
PT2175884T
(pt)
|
2007-07-12 |
2016-09-21 |
Gitr Inc |
Terapias de combinação empregando moléculas de ligação a gitr
|
|
EP2044949A1
(en)
|
2007-10-05 |
2009-04-08 |
Immutep |
Use of recombinant lag-3 or the derivatives thereof for eliciting monocyte immune response
|
|
US20110065633A1
(en)
|
2008-01-30 |
2011-03-17 |
Indiana University Research And Technology Corporation |
Ester-based peptide prodrugs
|
|
PE20091953A1
(es)
|
2008-05-08 |
2010-01-09 |
Du Pont |
Azoles sustituidos como fungicidas
|
|
AR072999A1
(es)
|
2008-08-11 |
2010-10-06 |
Medarex Inc |
Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
|
|
MX2011001872A
(es)
|
2008-08-18 |
2011-05-23 |
Univ Yale |
Moduladores de mif.
|
|
US9643922B2
(en)
|
2008-08-18 |
2017-05-09 |
Yale University |
MIF modulators
|
|
MX356367B
(es)
|
2008-12-09 |
2018-05-25 |
Genentech Inc |
Anticuerpos anti-pd-l1 y su uso para mejorar la funcion de celulas t.
|
|
JP5643233B2
(ja)
*
|
2009-02-10 |
2014-12-17 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプJanssen Pharmaceutica Naamloze Vennootschap |
プロリルヒドロキシラーゼ阻害物質としてのキナゾリノン
|
|
US8969342B2
(en)
|
2009-03-20 |
2015-03-03 |
Brandeis University |
Compounds and methods for treating mammalian gastrointestinal microbial infections
|
|
US8193235B2
(en)
|
2009-06-12 |
2012-06-05 |
University Of Kansas |
Compositions and methods for establishing and maintaining stem cells in an undifferentiated state
|
|
US8993698B2
(en)
|
2009-07-08 |
2015-03-31 |
Isp Investments Inc. |
4- and 5 substituted 1,2,3-triazole moieties with at least one remote polymerizable moiety and polymers thereof
|
|
IN2015DN02826A
(enExample)
|
2009-09-03 |
2015-09-11 |
Merck Sharp & Dohme |
|
|
WO2011050284A1
(en)
|
2009-10-23 |
2011-04-28 |
Glaxosmithkline Llc |
Pyrazolylpyridine antiviral agents
|
|
DK2510010T3
(en)
|
2009-12-10 |
2015-12-14 |
Hoffmann La Roche |
Antibodies that bind to human CSF1R extracellular domain 4 and their use
|
|
EP2525829A1
(en)
|
2010-01-22 |
2012-11-28 |
Ascendis Pharma A/S |
Dipeptide-based prodrug linkers for aromatic amine-containing drugs
|
|
ES2586231T3
(es)
|
2010-03-03 |
2016-10-13 |
Probiodrug Ag |
Inhibidores de glutaminil ciclasa
|
|
DK2542256T3
(da)
|
2010-03-04 |
2019-08-26 |
Macrogenics Inc |
Antistoffer reagerende med b7-h3, immunologisk aktive fragmenter deraf og anvendelser deraf
|
|
CN102918061B
(zh)
|
2010-03-05 |
2016-06-08 |
霍夫曼-拉罗奇有限公司 |
针对人csf-1r的抗体及其用途
|
|
RU2617971C2
(ru)
|
2010-03-05 |
2017-04-28 |
Ф.Хоффманн-Ля Рош Аг |
Антитела против csf-1r человека и их применение
|
|
SG10201502484SA
(en)
|
2010-03-30 |
2015-05-28 |
Verseon Corp |
Multisubstituted aromatic compounds as inhibitors of thrombin
|
|
EP3943154A1
(en)
|
2010-05-04 |
2022-01-26 |
Five Prime Therapeutics, Inc. |
Antibodies that bind csf1r
|
|
NZ729044A
(en)
|
2010-09-09 |
2020-07-31 |
Pfizer |
4-1bb binding molecules
|
|
US8748435B2
(en)
*
|
2011-04-01 |
2014-06-10 |
Novartis Ag |
Pyrazolo pyrimidine derivatives
|
|
CA2833636A1
(en)
|
2011-04-20 |
2012-10-26 |
Amplimmune, Inc. |
Antibodies and other molecules that bind b7-h1 and pd-1
|
|
BR112014012819B1
(pt)
|
2011-11-28 |
2022-08-16 |
Merck Patent Gmbh |
Anticorpo anti-pd-l1 ou fragmento de ligação ao antígeno do mesmo e composição
|
|
WO2013085890A1
(en)
|
2011-12-06 |
2013-06-13 |
Glaxo Group Limited |
Therapeutic methods
|
|
MX356337B
(es)
|
2011-12-15 |
2018-05-23 |
Hoffmann La Roche |
Anticuerpos contra csf-1r humano y sus usos.
|
|
MX2014008961A
(es)
|
2012-02-06 |
2014-10-14 |
Genentech Inc |
Composiciones y metodos para utilizar inhibidores de csf1r.
|
|
DK2820006T3
(da)
*
|
2012-02-29 |
2017-11-06 |
Chemocentryx Inc |
Pyrazol-1-yl benzen sulfonamider som ccr9 antagonister
|
|
AR090263A1
(es)
|
2012-03-08 |
2014-10-29 |
Hoffmann La Roche |
Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma
|
|
DE102012102162A1
(de)
|
2012-03-14 |
2013-09-19 |
Westfälische Wilhelms-Universität Münster Körperschaft des öffentlichen Rechts |
Ionenleitende polymere Verbindung für elektrochemische Zellen
|
|
KR20150018533A
(ko)
|
2012-05-11 |
2015-02-23 |
파이브 프라임 테라퓨틱스, 인크. |
콜로니 자극 인자 1 수용체(csf1r)에 결속하는 항체들에 의한 질병 상태의 치료 방법
|
|
AR091649A1
(es)
|
2012-07-02 |
2015-02-18 |
Bristol Myers Squibb Co |
Optimizacion de anticuerpos que se fijan al gen de activacion de linfocitos 3 (lag-3) y sus usos
|
|
CN107759690A
(zh)
|
2012-08-31 |
2018-03-06 |
戊瑞治疗有限公司 |
用结合群落刺激因子1受体(csf1r)的抗体治疗病状的方法
|
|
EP3363434A1
(en)
|
2013-03-14 |
2018-08-22 |
Epizyme Inc |
Arginine methyltransferase inhibitors and uses thereof
|
|
US9884806B2
(en)
|
2013-08-30 |
2018-02-06 |
Icahn School Of Medicine At Mount Sinai |
Cyclic vinylogous amides as bromodomain inhibitors
|
|
EP2903044A1
(de)
|
2014-02-04 |
2015-08-05 |
cynora GmbH |
Organische Moleküle zur Verwendung in optoelektronischen Bauelementen
|
|
WO2015167825A1
(en)
|
2014-04-29 |
2015-11-05 |
Emory University |
Prostaglandin receptor ep2 antagonists, derivatives, compositions, and uses related thereto
|
|
US20160251341A1
(en)
|
2015-02-27 |
2016-09-01 |
Verseon Corporation |
Substituted triazole compounds as serine protease inhibitors
|
|
EP3347008B1
(en)
|
2015-09-11 |
2022-03-09 |
Venatorx Pharmaceuticals, Inc. |
Beta-lactamase inhibitors
|
|
MX389798B
(es)
|
2017-01-20 |
2025-03-20 |
Arcus Biosciences Inc |
Azolopirimidina para el tratamiento de trastornos relacionados con el cáncer.
|
|
EP3618829B1
(en)
|
2017-05-05 |
2023-06-07 |
Arcus Biosciences, Inc. |
Quinazoline-pyridine derivatives for the treatment of cancer-related disorders
|