JP2019535720A5 - - Google Patents

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Publication number
JP2019535720A5
JP2019535720A5 JP2019526226A JP2019526226A JP2019535720A5 JP 2019535720 A5 JP2019535720 A5 JP 2019535720A5 JP 2019526226 A JP2019526226 A JP 2019526226A JP 2019526226 A JP2019526226 A JP 2019526226A JP 2019535720 A5 JP2019535720 A5 JP 2019535720A5
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cancer
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JP2019526226A
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Japanese (ja)
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JP2019535720A (ja
JP7150712B2 (ja
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Priority claimed from PCT/US2017/062166 external-priority patent/WO2018094148A1/en
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JP2019526226A 2016-11-18 2017-11-17 Cd73媒介免疫抑制の阻害剤 Active JP7150712B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662424241P 2016-11-18 2016-11-18
US62/424,241 2016-11-18
PCT/US2017/062166 WO2018094148A1 (en) 2016-11-18 2017-11-17 Inhibitors of cd73-mediated immunosuppression

Publications (3)

Publication Number Publication Date
JP2019535720A JP2019535720A (ja) 2019-12-12
JP2019535720A5 true JP2019535720A5 (enExample) 2020-12-24
JP7150712B2 JP7150712B2 (ja) 2022-10-11

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ID=62145728

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019526226A Active JP7150712B2 (ja) 2016-11-18 2017-11-17 Cd73媒介免疫抑制の阻害剤

Country Status (6)

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US (1) US11267845B2 (enExample)
EP (1) EP3541396A4 (enExample)
JP (1) JP7150712B2 (enExample)
CN (1) CN110022881B (enExample)
TW (1) TWI786072B (enExample)
WO (1) WO2018094148A1 (enExample)

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WO2018094148A1 (en) 2016-11-18 2018-05-24 Arcus Biosciences, Inc. Inhibitors of cd73-mediated immunosuppression
CN110382544B (zh) 2017-03-16 2023-12-22 先天制药公司 用于治疗癌症的组合物和方法
US11129841B2 (en) 2017-05-10 2021-09-28 Oric Pharmaceuticals, Inc. CD73 inhibitors
SG11202002192QA (en) 2017-10-06 2020-04-29 Innate Pharma Restoration of t cell activity via the cd39/cd73 axis
US11377469B2 (en) 2017-11-03 2022-07-05 Oric Pharmaceuticals, Inc. CD73 inhibitors
CN112004541A (zh) 2018-03-09 2020-11-27 艾库斯生物科学有限公司 肠道外给药的免疫增强药物
AU2019261976B2 (en) 2018-04-30 2025-01-23 Oric Pharmaceuticals, Inc. CD73 inhibitors
WO2019232319A1 (en) 2018-05-31 2019-12-05 Peloton Therapeutics, Inc. Compositions and methods for inhibiting cd73
AU2019289646B2 (en) 2018-06-18 2025-10-23 Innate Pharma Compositions and methods for treating cancer
WO2020047082A1 (en) * 2018-08-28 2020-03-05 Eternity Bioscience Inc. Cd73 inhibitors and therapeutic uses thereof
US11530234B2 (en) 2018-09-11 2022-12-20 Risen (Suzhou) Pharma Tech Co., Ltd. CD73 inhibitors and pharmaceutical uses thereof
CN110885352B (zh) * 2018-09-11 2023-02-24 润佳(苏州)医药科技有限公司 Cd73抑制剂及其药学应用
US10881681B2 (en) 2018-09-11 2021-01-05 Risen (Suzhou) Pharma Tech Co., Ltd. CD73 inhibitors and pharmaceutical uses thereof
KR20210114963A (ko) 2019-01-11 2021-09-24 오메로스 코포레이션 암을 치료하기 위한 방법 및 조성물
WO2020151707A1 (zh) * 2019-01-22 2020-07-30 江苏恒瑞医药股份有限公司 一种新型的小分子cd73抑制剂、其制备方法及其在医药上的应用
KR20210137162A (ko) * 2019-03-12 2021-11-17 아르커스 바이오사이언시즈 인코포레이티드 종양유전자-유발 암의 치료
CN113874397A (zh) 2019-03-29 2021-12-31 艾库斯生物科学有限公司 利用鉴定的腺苷指纹治疗癌症
PT4051688T (pt) 2019-10-30 2025-06-30 Oric Pharmaceuticals Inc Inibidores de cd73
EP4121409A1 (en) 2020-03-19 2023-01-25 Arcus Biosciences, Inc. Tetralin and tetrahydroquinoline compounds as inhibitors of hif-2alpha
PE20231078A1 (es) 2020-06-02 2023-07-17 Arcus Biosciences Inc Anticuerpos anti-tigit
US20240226115A1 (en) 2021-05-21 2024-07-11 Arcus Biosciences, Inc. Axl inhibitor compounds
WO2022246177A1 (en) 2021-05-21 2022-11-24 Arcus Biosciences, Inc. Axl compounds
IL312348A (en) 2021-10-29 2024-06-01 Arcus Biosciences Inc HIF-2ALPHA inhibitors and methods of using it
CA3256033A1 (en) 2022-04-13 2023-10-19 Arcus Biosciences, Inc. POLYTHERAPY FOR THE TREATMENT OF CANCERS EXPRESSING TOO MUCH-2
CA3256561A1 (en) 2022-05-02 2023-11-09 Arcus Biosciences, Inc. Anti-tigit antibodies and their uses
WO2023241699A1 (zh) * 2022-06-17 2023-12-21 上海森辉医药有限公司 一种环戊基腺苷衍生物及其药物用途
EP4554680A1 (en) 2022-07-15 2025-05-21 Arcus Biosciences, Inc. Inhibitors of hpk1 and methods of use thereof
WO2024020034A1 (en) 2022-07-20 2024-01-25 Arcus Biosciences, Inc. Cbl-b inhibitors and methods of use thereof
EP4587001A1 (en) 2022-09-14 2025-07-23 Arcus Biosciences, Inc. Dispersions of etrumadenant
WO2024081385A1 (en) 2022-10-14 2024-04-18 Arcus Biosciences, Inc. Hpk1 inhibitors and methods of use thereof
WO2024233360A1 (en) 2023-05-05 2024-11-14 Arcus Biosciences, Inc. Cbl-b inhibitors and methods of use thereof
CN116298323B (zh) * 2023-05-16 2023-08-22 南京联笃生物科技有限公司 一种用于诊断狼疮性肾炎的生物标志物及应用
US20250011318A1 (en) 2023-05-25 2025-01-09 Arcus Biosciences, Inc. Cbl-b inhibitors and methods of use thereof
WO2025054339A1 (en) 2023-09-08 2025-03-13 Arcus Biosciences, Inc. Triazolopyridine compounds as inhibitors of kit
WO2025072330A1 (en) 2023-09-26 2025-04-03 Arcus Biosciences, Inc. Kit inhibitor compounds and methods of use thereof
WO2025076299A1 (en) 2023-10-06 2025-04-10 Arcus Biosciences, Inc. Cbl-b inhibitors and methods of use thereof
WO2025096979A1 (en) 2023-11-02 2025-05-08 Arcus Biosciences, Inc. Thiazole compounds as kit inhibitors and methods of use thereof
WO2025119278A1 (zh) * 2023-12-07 2025-06-12 无锡和誉生物医药科技有限公司 一种cd73抑制剂药物组合物,其制备方法和应用
WO2025137640A1 (en) 2023-12-22 2025-06-26 Gilead Sciences, Inc. Azaspiro wrn inhibitors
WO2025193759A1 (en) 2024-03-12 2025-09-18 Gilead Sciences, Inc. Solid forms of an azolopyrimidine compound
WO2025233264A1 (en) 2024-05-07 2025-11-13 Innate Pharma Use of cd73 blocking agents in combination with anti-cd20 x cd3 t cell engagers
WO2026006759A1 (en) 2024-06-28 2026-01-02 Arcus Biosciences, Inc. Pharmaceutical compositions, dosage forms, and methods of making and using same

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IL108523A0 (en) 1993-02-03 1994-05-30 Gensia Inc Pharmaceutical compositions containing adenosine kinase inhibitors for preventing or treating conditions involving inflammatory responses and pain
US5569650A (en) * 1993-06-11 1996-10-29 Sloan-Kettering Institute For Cancer Research C-nucleoside isosters of analogs thereof and pharmaceutical compositions
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EP1860113A1 (en) * 2006-05-24 2007-11-28 Rheinische Friedrich-Wilhelms-Universität Bonn Ectonucleotidase inhibitors
US20110245088A1 (en) * 2010-04-05 2011-10-06 National Tsing Hua University Amide-based solution-phase derived library and method for screening thereof
US9090697B2 (en) 2013-03-15 2015-07-28 Bayer Healthcare Llc Methods for treating bleeding disorders
WO2015164573A1 (en) * 2014-04-25 2015-10-29 Vitae Pharmaceuticals, Inc. Purine derivatives as cd73 inhibitors for the treatment of cancer
IL260260B2 (en) * 2016-01-08 2024-01-01 Arcus Biosciences Inc Modulators of 5'-nucleotidase, ecto and the use thereof
WO2018094148A1 (en) 2016-11-18 2018-05-24 Arcus Biosciences, Inc. Inhibitors of cd73-mediated immunosuppression

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