|
US798959A
(en)
|
1904-12-19 |
1905-09-05 |
George W Goss |
Corn-husker.
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
JPS6098584A
(ja)
|
1983-11-02 |
1985-06-01 |
Canon Inc |
カメラ―体形vtr
|
|
US5807715A
(en)
|
1984-08-27 |
1998-09-15 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin
|
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
|
US6548640B1
(en)
|
1986-03-27 |
2003-04-15 |
Btg International Limited |
Altered antibodies
|
|
IL85035A0
(en)
|
1987-01-08 |
1988-06-30 |
Int Genetic Eng |
Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
|
|
DE3883899T3
(de)
|
1987-03-18 |
1999-04-22 |
Sb2, Inc., Danville, Calif. |
Geänderte antikörper.
|
|
ATE102631T1
(de)
|
1988-11-11 |
1994-03-15 |
Medical Res Council |
Klonierung von immunglobulin sequenzen aus den variabelen domaenen.
|
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
|
CA2023779A1
(en)
|
1989-08-23 |
1991-02-24 |
Margaret D. Moore |
Compositions and methods for detection and treatment of epstein-barr virus infection and immune disorders
|
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US5256643A
(en)
|
1990-05-29 |
1993-10-26 |
The Government Of The United States |
Human cripto protein
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
AU9016591A
(en)
|
1990-10-25 |
1992-05-26 |
Tanox Biosystems, Inc. |
Glycoproteins associated with membrane-bound immunoglobulins as antibody targets on B cells
|
|
CA2095633C
(en)
|
1990-12-03 |
2003-02-04 |
Lisa J. Garrard |
Enrichment method for variant proteins with altered binding properties
|
|
US5571894A
(en)
|
1991-02-05 |
1996-11-05 |
Ciba-Geigy Corporation |
Recombinant antibodies specific for a growth factor receptor
|
|
CA2407304A1
(en)
|
1991-03-29 |
1992-10-15 |
Genentech, Inc. |
Human pf4a receptors and their use
|
|
US5543503A
(en)
|
1991-03-29 |
1996-08-06 |
Genentech Inc. |
Antibodies to human IL-8 type A receptor
|
|
US5440021A
(en)
|
1991-03-29 |
1995-08-08 |
Chuntharapai; Anan |
Antibodies to human IL-8 type B receptor
|
|
EP0940468A1
(en)
|
1991-06-14 |
1999-09-08 |
Genentech, Inc. |
Humanized antibody variable domain
|
|
GB9114948D0
(en)
|
1991-07-11 |
1991-08-28 |
Pfizer Ltd |
Process for preparing sertraline intermediates
|
|
JP3050424B2
(ja)
|
1991-07-12 |
2000-06-12 |
塩野義製薬株式会社 |
ヒトエンドセリンリセプター
|
|
US5264557A
(en)
|
1991-08-23 |
1993-11-23 |
The United States Of America As Represented By The Department Of Health And Human Services |
Polypeptide of a human cripto-related gene, CR-3
|
|
FI941572A7
(fi)
|
1991-10-07 |
1994-05-27 |
Oncologix Inc |
Anti-erbB-2-monoklonaalisten vasta-aineiden yhdistelmä ja käyttömenete lmä
|
|
WO1993008829A1
(en)
|
1991-11-04 |
1993-05-13 |
The Regents Of The University Of California |
Compositions that mediate killing of hiv-infected cells
|
|
US6011146A
(en)
|
1991-11-15 |
2000-01-04 |
Institut Pasteur |
Altered major histocompatibility complex (MHC) determinant and methods of using the determinant
|
|
US6153408A
(en)
|
1991-11-15 |
2000-11-28 |
Institut Pasteur And Institut National De La Sante Et De La Recherche Medicale |
Altered major histocompatibility complex (MHC) determinant and methods of using the determinant
|
|
DE69334255D1
(de)
|
1992-02-06 |
2009-02-12 |
Novartis Vaccines & Diagnostic |
Marker für Krebs und biosynthetisches Bindeprotein dafür
|
|
IL107366A
(en)
|
1992-10-23 |
2003-03-12 |
Chugai Pharmaceutical Co Ltd |
Genes coding for megakaryocyte potentiator
|
|
US5644033A
(en)
|
1992-12-22 |
1997-07-01 |
Health Research, Inc. |
Monoclonal antibodies that define a unique antigen of human B cell antigen receptor complex and methods of using same for diagnosis and treatment
|
|
US5869445A
(en)
|
1993-03-17 |
1999-02-09 |
University Of Washington |
Methods for eliciting or enhancing reactivity to HER-2/neu protein
|
|
US5801005A
(en)
|
1993-03-17 |
1998-09-01 |
University Of Washington |
Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
|
|
WO1994029351A2
(en)
|
1993-06-16 |
1994-12-22 |
Celltech Limited |
Antibodies
|
|
US5773223A
(en)
|
1993-09-02 |
1998-06-30 |
Chiron Corporation |
Endothelin B1, (ETB1) receptor polypeptide and its encoding nucleic acid methods, and uses thereof
|
|
WO2001016318A2
(en)
|
1999-09-01 |
2001-03-08 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US5750370A
(en)
|
1995-06-06 |
1998-05-12 |
Human Genome Sciences, Inc. |
Nucleic acid encoding human endothlein-bombesin receptor and method of producing the receptor
|
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
|
US5869046A
(en)
|
1995-04-14 |
1999-02-09 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
|
US5707829A
(en)
|
1995-08-11 |
1998-01-13 |
Genetics Institute, Inc. |
DNA sequences and secreted proteins encoded thereby
|
|
US20020193567A1
(en)
|
1995-08-11 |
2002-12-19 |
Genetics Institute, Inc. |
Secreted proteins and polynucleotides encoding them
|
|
JP3646191B2
(ja)
|
1996-03-19 |
2005-05-11 |
大塚製薬株式会社 |
ヒト遺伝子
|
|
NZ332598A
(en)
|
1996-05-17 |
2000-04-28 |
Schering Corp |
Human BAS-1 protein, and use as an antagonist for modulating physiology or development of a cell
|
|
US5945511A
(en)
|
1997-02-20 |
1999-08-31 |
Zymogenetics, Inc. |
Class II cytokine receptor
|
|
US7033827B2
(en)
|
1997-02-25 |
2006-04-25 |
Corixa Corporation |
Prostate-specific polynucleotide compositions
|
|
US20030185830A1
(en)
|
1997-02-25 |
2003-10-02 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of prostate cancer
|
|
US6261791B1
(en)
|
1997-03-10 |
2001-07-17 |
The Regents Of The University Of California |
Method for diagnosing cancer using specific PSCA antibodies
|
|
CA2281877C
(en)
|
1997-03-10 |
2010-01-05 |
The Regents Of The University Of California |
Psca: prostate stem cell antigen
|
|
US6541212B2
(en)
|
1997-03-10 |
2003-04-01 |
The Regents Of The University Of California |
Methods for detecting prostate stem cell antigen protein
|
|
US6555339B1
(en)
|
1997-04-14 |
2003-04-29 |
Arena Pharmaceuticals, Inc. |
Non-endogenous, constitutively activated human protein-coupled receptors
|
|
US6319688B1
(en)
|
1997-04-28 |
2001-11-20 |
Smithkline Beecham Corporation |
Polynucleotide encoding human sodium dependent phosphate transporter (IPT-1)
|
|
AU751659B2
(en)
|
1997-05-02 |
2002-08-22 |
Genentech Inc. |
A method for making multispecific antibodies having heteromultimeric and common components
|
|
WO1998051805A1
(en)
|
1997-05-15 |
1998-11-19 |
Abbott Laboratories |
Reagents and methods useful for detecting diseases of the prostate
|
|
WO1998051824A1
(en)
|
1997-05-15 |
1998-11-19 |
Abbott Laboratories |
Reagents and methods useful for detecting disease of the urinary tract
|
|
US6602677B1
(en)
|
1997-09-19 |
2003-08-05 |
Promega Corporation |
Thermostable luciferases and methods of production
|
|
US20030060612A1
(en)
|
1997-10-28 |
2003-03-27 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
US20020034749A1
(en)
|
1997-11-18 |
2002-03-21 |
Billing-Medel Patricia A. |
Reagents and methods useful for detecting diseases of the breast
|
|
US6610833B1
(en)
|
1997-11-24 |
2003-08-26 |
The Institute For Human Genetics And Biochemistry |
Monoclonal human natural antibodies
|
|
US6110695A
(en)
|
1997-12-02 |
2000-08-29 |
The Regents Of The University Of California |
Modulating the interaction of the chemokine, B Lymphocyte Hemoattractant, and its Receptor, BLR1
|
|
BR9813365A
(pt)
|
1997-12-05 |
2004-06-15 |
Scripps Research Inst |
Método para produção e humanização de um anticorpo monoclonal de rato
|
|
CA2323071C
(en)
|
1998-03-13 |
2011-06-21 |
The Burnham Institute |
Molecules that home to various selected organs or tissues
|
|
PT1068241E
(pt)
|
1998-04-02 |
2007-11-19 |
Genentech Inc |
Variantes de anticorpos e respectivos fragmentos
|
|
US6194551B1
(en)
|
1998-04-02 |
2001-02-27 |
Genentech, Inc. |
Polypeptide variants
|
|
US6534482B1
(en)
|
1998-05-13 |
2003-03-18 |
Epimmune, Inc. |
Expression vectors for stimulating an immune response and methods of using the same
|
|
US20030064397A1
(en)
|
1998-05-22 |
2003-04-03 |
Incyte Genomics, Inc. |
Transmembrane protein differentially expressed in prostate and lung tumors
|
|
US20020187472A1
(en)
|
2001-03-09 |
2002-12-12 |
Preeti Lal |
Steap-related protein
|
|
WO2000012130A1
(en)
|
1998-08-27 |
2000-03-09 |
Smithkline Beecham Corporation |
Rp105 agonists and antagonists
|
|
GB9818731D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Compounds
|
|
DK1413582T3
(da)
|
1998-08-27 |
2006-07-17 |
Spirogen Ltd |
Dimere pyrrolobenzodiazepiner
|
|
JP4689781B2
(ja)
|
1998-09-03 |
2011-05-25 |
独立行政法人科学技術振興機構 |
アミノ酸輸送蛋白及びその遺伝子
|
|
WO2000020579A1
(en)
|
1998-10-02 |
2000-04-13 |
Mcmaster University |
Spliced form of erbb-2/neu oncogene
|
|
WO2001057188A2
(en)
|
2000-02-03 |
2001-08-09 |
Hyseq, Inc. |
Novel nucleic acids and polypeptides
|
|
US6468546B1
(en)
|
1998-12-17 |
2002-10-22 |
Corixa Corporation |
Compositions and methods for therapy and diagnosis of ovarian cancer
|
|
US20020119158A1
(en)
|
1998-12-17 |
2002-08-29 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US20030091580A1
(en)
|
2001-06-18 |
2003-05-15 |
Mitcham Jennifer L. |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US6962980B2
(en)
|
1999-09-24 |
2005-11-08 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US6858710B2
(en)
|
1998-12-17 |
2005-02-22 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
AU776672B2
(en)
|
1998-12-30 |
2004-09-16 |
Beth Israel Deaconess Medical Center |
Characterization of a calcium channel family
|
|
US20030190669A1
(en)
|
1998-12-30 |
2003-10-09 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
KR101077001B1
(ko)
|
1999-01-15 |
2011-10-26 |
제넨테크, 인크. |
효과기 기능이 변화된 폴리펩티드 변이체
|
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
IL144371A0
(en)
|
1999-01-29 |
2002-05-23 |
Corixa Corp |
Her-2/neu fusion proteins
|
|
GB9905124D0
(en)
|
1999-03-05 |
1999-04-28 |
Smithkline Beecham Biolog |
Novel compounds
|
|
AU3395900A
(en)
|
1999-03-12 |
2000-10-04 |
Human Genome Sciences, Inc. |
Human lung cancer associated gene sequences and polypeptides
|
|
US7312303B2
(en)
|
1999-05-11 |
2007-12-25 |
Genentech, Inc. |
Anti-PRO4980 antibodies
|
|
AU4952600A
(en)
|
1999-06-03 |
2000-12-28 |
Takeda Chemical Industries Ltd. |
Screening method with the use of cd100
|
|
BR0012196A
(pt)
|
1999-06-25 |
2002-03-19 |
Genentech Inc |
Método de tratamento de um tumor em mamìferos através do uso de conjugados de maitansinóide e anticorpo receptor anti-erbb e artigo industrializado
|
|
US7589172B2
(en)
|
1999-07-20 |
2009-09-15 |
Genentech, Inc. |
PRO256 polypeptides
|
|
US7297770B2
(en)
|
1999-08-10 |
2007-11-20 |
Genentech, Inc. |
PRO6496 polypeptides
|
|
US7294696B2
(en)
|
1999-08-17 |
2007-11-13 |
Genentech Inc. |
PRO7168 polypeptides
|
|
US20030232056A1
(en)
|
1999-09-10 |
2003-12-18 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US20030129192A1
(en)
|
1999-09-10 |
2003-07-10 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
US20030206918A1
(en)
|
1999-09-10 |
2003-11-06 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of ovarian cancer
|
|
WO2001040309A2
(en)
|
1999-10-29 |
2001-06-07 |
Genentech, Inc. |
Anti-prostate stem cell antigen (psca) antibody compositions and methods of use
|
|
EP1235847B1
(en)
|
1999-11-29 |
2016-01-20 |
The Trustees of Columbia University in the City of New York |
ISOLATION OF FIVE NOVEL GENES CODING FOR NEW Fc RECEPTORS-TYPE MELANOMA INVOLVED IN THE PATHOGENESIS OF LYMPHOMA/MELANOMA
|
|
CA2392510A1
(en)
|
1999-11-30 |
2001-06-07 |
Corixa Corporation |
Compositions and methods for therapy and diagnosis of breast cancer
|
|
WO2001041787A1
(en)
|
1999-12-10 |
2001-06-14 |
Epimmune Inc. |
INDUCING CELLULAR IMMUNE RESPONSES TO HER2/neu USING PEPTIDE AND NUCLEIC ACID COMPOSITIONS
|
|
CA2393869A1
(en)
|
1999-12-15 |
2001-06-21 |
Genetech,Inc. |
Shotgun scanning, a combinatorial method for mapping functional protein epitopes
|
|
US6610286B2
(en)
|
1999-12-23 |
2003-08-26 |
Zymogenetics, Inc. |
Method for treating inflammation using soluble receptors to interleukin-20
|
|
JP4741139B2
(ja)
|
1999-12-23 |
2011-08-03 |
ザイモジェネティクス, インコーポレイテッド |
可溶性インターロイキン−20レセプター
|
|
NZ502058A
(en)
|
1999-12-23 |
2003-11-28 |
Ovita Ltd |
Isolated mutated nucleic acid molecule for regulation of ovulation rate
|
|
DE60043957D1
(de)
|
1999-12-23 |
2010-04-15 |
Zymogenetics Inc |
Verfahren zur Behandlung von Entzündungen
|
|
US7297333B2
(en)
|
2000-01-20 |
2007-11-20 |
Genentech, Inc. |
Anti-PRO10268 antibodies
|
|
US20020039573A1
(en)
|
2000-01-21 |
2002-04-04 |
Cheever Martin A. |
Compounds and methods for prevention and treatment of HER-2/neu associated malignancies
|
|
US20030224379A1
(en)
|
2000-01-21 |
2003-12-04 |
Tang Y. Tom |
Novel nucleic acids and polypeptides
|
|
US20030186372A1
(en)
|
2000-02-11 |
2003-10-02 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US20030219806A1
(en)
|
2000-02-22 |
2003-11-27 |
Millennium Pharmaceuticals, Inc. |
Novel 18607, 15603, 69318, 12303, 48000, 52920, 5433, 38554, 57301, 58324, 55063, 52991, 59914, 59921 and 33751 molecules and uses therefor
|
|
AU2001238596A1
(en)
|
2000-02-22 |
2001-09-03 |
Millennium Pharmaceuticals, Inc. |
18607, a novel human calcium channel
|
|
US20040002068A1
(en)
|
2000-03-01 |
2004-01-01 |
Corixa Corporation |
Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
|
|
US20040005561A1
(en)
|
2000-03-01 |
2004-01-08 |
Corixa Corporation |
Compositions and methods for the detection, diagnosis and therapy of hematological malignancies
|
|
AU2001245280A1
(en)
|
2000-03-07 |
2001-09-17 |
Hyseq, Inc. |
Novel nucleic acids and polypeptides
|
|
JP2004521602A
(ja)
|
2000-03-24 |
2004-07-22 |
ファハリ サッチオグリュ |
前立腺特異的または精巣特異的な新規の核酸分子、ポリペプチド、ならびに診断法および治療法
|
|
AU2001250412A1
(en)
|
2000-03-31 |
2001-10-08 |
Ipf Pharmaceuticals Gmbh |
Diagnostic and medicament for analysing the cell surface proteome of tumour and inflammatory cells and for treating tumorous and inflammatory diseases, preferably using specific chemokine receptor analysis and the chemokine receptor-ligand interaction
|
|
US7279294B2
(en)
|
2000-04-03 |
2007-10-09 |
The United States Of America As Represented By The Secretary, Dept. Of Health And Human Services, Nih |
Tumor markers in ovarian cancer
|
|
AU2001249885A1
(en)
|
2000-04-07 |
2001-10-23 |
Arena Pharmaceuticals, Inc. |
Non-endogenous, constitutively activated known g protein-coupled receptors
|
|
MXPA02010011A
(es)
|
2000-04-11 |
2003-04-25 |
Genentech Inc |
Anticuerpos multivalentes y usos para los mismos.
|
|
WO2001088133A2
(en)
|
2000-05-18 |
2001-11-22 |
Lexicon Genetics Incorporated |
Human semaphorin homologs and polynucleotides encoding the same
|
|
AU2001274888A1
(en)
|
2000-05-19 |
2001-12-03 |
Human Genome Sciences, Inc. |
Nucleic acids, proteins, and antibodies
|
|
AU2001275437A1
(en)
|
2000-06-09 |
2001-12-17 |
Idec Pharmaceuticals Corporation |
Gene targets and ligands that bind thereto for treatment and diagnosis of ovarian carcinomas
|
|
AU2001268471A1
(en)
|
2000-06-16 |
2002-01-02 |
Incyte Genomics, Inc. |
G-protein coupled receptors
|
|
EP1383892A2
(en)
|
2000-06-30 |
2004-01-28 |
Incyte Genomics, Inc. |
Human extracellular matrix and cell adhesion polypeptides
|
|
JP2004502417A
(ja)
|
2000-06-30 |
2004-01-29 |
アムジェン インコーポレーテッド |
B7様分子およびその使用
|
|
CA2406649A1
(en)
|
2000-06-30 |
2002-01-10 |
Human Genome Sciences, Inc. |
B7-like polynucleotides, polypeptides, and antibodies
|
|
WO2002006339A2
(en)
|
2000-07-03 |
2002-01-24 |
Curagen Corporation |
Proteins and nucleic acids encoding same
|
|
US20040044179A1
(en)
|
2000-07-25 |
2004-03-04 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
WO2002010187A1
(en)
|
2000-07-27 |
2002-02-07 |
Mayo Foundation For Medical Education And Research |
B7-h3 and b7-h4, novel immunoregulatory molecules
|
|
AU2001287639A1
(en)
|
2000-07-28 |
2002-02-13 |
Ulrich Wissenbach |
Trp8, trp9 and trp10, markers for cancer
|
|
US7229623B1
(en)
|
2000-08-03 |
2007-06-12 |
Corixa Corporation |
Her-2/neu fusion proteins
|
|
AU2001283360A1
(en)
|
2000-08-14 |
2002-02-25 |
Corixa Corporation |
Methods for diagnosis and therapy of hematological and virus-associated malignancies
|
|
HUP0600780A2
(en)
|
2000-08-14 |
2007-01-29 |
Corixa Corp |
Compositions and methods for the therapy and diagnosis of her-2/neu-associated malignancies
|
|
JP2004520806A
(ja)
|
2000-08-24 |
2004-07-15 |
ジェネンテック・インコーポレーテッド |
腫瘍の診断と治療のための組成物と方法
|
|
GB0020953D0
(en)
|
2000-08-24 |
2000-10-11 |
Smithkline Beecham Biolog |
Vaccine
|
|
WO2002022660A2
(en)
|
2000-09-11 |
2002-03-21 |
Hyseq, Inc. |
Novel nucleic acids and polypeptides
|
|
US6613567B1
(en)
|
2000-09-15 |
2003-09-02 |
Isis Pharmaceuticals, Inc. |
Antisense inhibition of Her-2 expression
|
|
DE60121808T2
(de)
|
2000-09-15 |
2007-03-29 |
Zymogenetics, Inc., Seattle |
Verwendung eines polypeptids, welches die extrazelluläre domäne von il-20ra und il-20rb enthält, zur behandlung von entzündungen
|
|
US7491797B2
(en)
|
2000-09-15 |
2009-02-17 |
Genentech, Inc. |
PRO6308 polypeptide
|
|
UA83458C2
(uk)
|
2000-09-18 |
2008-07-25 |
Байоджен Айдек Ма Інк. |
Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf)
|
|
AU2001292724B2
(en)
|
2000-09-18 |
2005-05-26 |
Biogen Idec Ma Inc. |
CRIPTO mutant and uses thereof
|
|
AU2002215345A1
(en)
|
2000-10-13 |
2002-04-22 |
Eos Biotechnology, Inc. |
Methods of diagnosis of prostate cancer, compositions and methods of screening for modulators of prostate cancer
|
|
US6596541B2
(en)
|
2000-10-31 |
2003-07-22 |
Regeneron Pharmaceuticals, Inc. |
Methods of modifying eukaryotic cells
|
|
AU2002230659A1
(en)
|
2000-11-07 |
2002-05-21 |
Zymogenetics Inc. |
Human tumor necrosis factor receptor
|
|
US20020150573A1
(en)
|
2000-11-10 |
2002-10-17 |
The Rockefeller University |
Anti-Igalpha-Igbeta antibody for lymphoma therapy
|
|
ES2405944T3
(es)
|
2000-11-30 |
2013-06-04 |
Medarex, Inc. |
Ácidos nucleicos que codifican las secuencias de inmunoglobulina humana reorganizadas a partir de ratones transcromoscómicos transgénicos
zadas
|
|
WO2002061087A2
(en)
|
2000-12-19 |
2002-08-08 |
Lifespan Biosciences, Inc. |
Antigenic peptides, such as for g protein-coupled receptors (gpcrs), antibodies thereto, and systems for identifying such antigenic peptides
|
|
EP1357828A2
(en)
|
2001-01-12 |
2003-11-05 |
University of Medicine and Dentistry of New Jersey |
Bone morphogenetic protein-2 in the treatment and diagnosis of cancer
|
|
US20030119119A1
(en)
|
2001-01-16 |
2003-06-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US20030119126A1
(en)
|
2001-01-16 |
2003-06-26 |
Genentech, Inc. |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
JP2005503760A
(ja)
|
2001-01-24 |
2005-02-10 |
プロテイン デザイン ラブス, インコーポレイテッド |
乳癌の診断方法、組成物および乳癌のモジュレーターのスクリーニング方法
|
|
WO2002060317A2
(en)
|
2001-01-30 |
2002-08-08 |
Corixa Corporation |
Compositions and methods for the therapy and diagnosis of pancreatic cancer
|
|
WO2002064775A1
(en)
|
2001-02-12 |
2002-08-22 |
Bionomics Limited |
Identification of genes involved in the tumourigenic process
|
|
AU2002258518A1
(en)
|
2001-03-14 |
2002-09-24 |
Millennium Pharmaceuticals, Inc. |
Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer
|
|
US20040236091A1
(en)
|
2001-03-28 |
2004-11-25 |
Chicz Roman M. |
Translational profiling
|
|
WO2003008537A2
(en)
|
2001-04-06 |
2003-01-30 |
Mannkind Corporation |
Epitope sequences
|
|
US6820011B2
(en)
|
2001-04-11 |
2004-11-16 |
The Regents Of The University Of Colorado |
Three-dimensional structure of complement receptor type 2 and uses thereof
|
|
JP5232350B2
(ja)
|
2001-04-17 |
2013-07-10 |
ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ アーカンソー |
Ca125遺伝子のリピート配列並びに診断および治療的介入のためのその使用
|
|
JP2005527180A
(ja)
|
2001-04-18 |
2005-09-15 |
プロテイン デザイン ラブス, インコーポレイテッド |
肺がんの診断方法、肺がんの修飾因子の組成及びスクリーニングの方法
|
|
AU2002334799B2
(en)
|
2001-04-26 |
2009-05-07 |
Biogen Ma Inc. |
Cripto-specific antibodies
|
|
MXPA03009797A
(es)
|
2001-04-26 |
2004-01-29 |
Biogen Inc |
ANTICUERPOS PARA BLOQUEO DE PROTEiNA CRIPTO Y USO DE LOS MISMOS.
|
|
JP2005504513A
(ja)
|
2001-05-09 |
2005-02-17 |
コリクサ コーポレイション |
前立腺癌の治療及び診断のための組成物及び方法
|
|
WO2002092836A2
(en)
|
2001-05-11 |
2002-11-21 |
Sloan-Kettering Institute For Cancer Research |
Nucleic acid sequence encoding ovarian antigen, ca125, and uses thereof
|
|
ATE446771T1
(de)
|
2001-05-24 |
2009-11-15 |
Zymogenetics Inc |
Taci-immunoglobulin-fusionsproteine
|
|
AU2002314901A1
(en)
|
2001-06-04 |
2002-12-16 |
Eos Biotechnology, Inc. |
Methods of diagnosis and treatment of androgen-dependent prostate cancer, prostate cancer undergoing androgen-withdrawal, and androgen-independent prostate cancer
|
|
JP2005518185A
(ja)
|
2001-06-04 |
2005-06-23 |
キュラジェン コーポレイション |
新規タンパク質およびそれをコード化する核酸
|
|
AU2002320264B2
(en)
|
2001-06-05 |
2008-05-01 |
Exelixis, Inc. |
GFATs as modifiers of the p53 pathway and methods of use
|
|
JP2005505257A
(ja)
|
2001-06-05 |
2005-02-24 |
エクセリクシス・インコーポレイテッド |
p53経路のモディファイヤーとしてのIGsおよび使用方法
|
|
US7235358B2
(en)
|
2001-06-08 |
2007-06-26 |
Expression Diagnostics, Inc. |
Methods and compositions for diagnosing and monitoring transplant rejection
|
|
WO2002101075A2
(en)
|
2001-06-13 |
2002-12-19 |
Millennium Pharmaceuticals, Inc. |
Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of cervical cancer
|
|
US7189507B2
(en)
|
2001-06-18 |
2007-03-13 |
Pdl Biopharma, Inc. |
Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
|
|
JP2005508144A
(ja)
|
2001-06-18 |
2005-03-31 |
イオス バイオテクノロジー,インコーポレイティド |
卵巣癌の診断方法、卵巣癌のモジュレーターをスクリーニングする組成物及び方法
|
|
WO2003004989A2
(en)
|
2001-06-21 |
2003-01-16 |
Millennium Pharmaceuticals, Inc. |
Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer
|
|
WO2003002717A2
(en)
|
2001-06-28 |
2003-01-09 |
Schering Corporation |
Biological activity of ak155
|
|
US20030120040A1
(en)
|
2001-06-29 |
2003-06-26 |
Genentech, Inc. |
Secreted and Transmembrane polypeptides and nucleic acids encoding the same
|
|
AU2002314433A1
(en)
|
2001-07-02 |
2003-01-21 |
Licentia Ltd. |
Ephrin-tie receptor materials and methods
|
|
US20040076955A1
(en)
|
2001-07-03 |
2004-04-22 |
Eos Biotechnology, Inc. |
Methods of diagnosis of bladder cancer, compositions and methods of screening for modulators of bladder cancer
|
|
WO2003003984A2
(en)
|
2001-07-05 |
2003-01-16 |
Curagen Corporation |
Novel proteins and nucleic acids encoding same
|
|
US7446185B2
(en)
|
2001-07-18 |
2008-11-04 |
The Regents Of The University Of California |
Her2/neu target antigen and use of same to stimulate an immune response
|
|
WO2003009814A2
(en)
|
2001-07-25 |
2003-02-06 |
Millennium Pharmaceuticals, Inc. |
Novel genes, compositions, kits, and methods for identification, assessment, prevention, and therapy of prostate cancer
|
|
WO2003014294A2
(en)
|
2001-08-03 |
2003-02-20 |
Genentech, Inc. |
Tacis and br3 polypeptides and uses thereof
|
|
EP1478772A2
(en)
|
2001-08-14 |
2004-11-24 |
The General Hospital Corporation |
Nucleic acid and amino acid sequences involved in pain
|
|
US20030092013A1
(en)
|
2001-08-16 |
2003-05-15 |
Vitivity, Inc. |
Diagnosis and treatment of vascular disease
|
|
WO2003018621A2
(en)
|
2001-08-23 |
2003-03-06 |
Oxford Biomedica (Uk) Limited |
Genes
|
|
WO2003029262A2
(en)
|
2001-08-29 |
2003-04-10 |
Vanderbilt University |
The human mob-5 (il-24) receptors and uses thereof
|
|
US20030124579A1
(en)
|
2001-09-05 |
2003-07-03 |
Eos Biotechnology, Inc. |
Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
|
|
CA2459318C
(en)
|
2001-09-06 |
2017-09-26 |
Agensys, Inc. |
Nucleic acid and corresponding protein entitled steap-1 useful in treatment and detection of cancer
|
|
CA2459219A1
(en)
|
2001-09-17 |
2003-03-27 |
Protein Design Labs, Inc. |
Methods of diagnosis of cancer compositions and methods of screening for modulators of cancer
|
|
WO2003025228A1
(en)
|
2001-09-18 |
2003-03-27 |
Proteologics, Inc. |
Methods and compositions for treating hcap associated diseases
|
|
JP2005536439A
(ja)
|
2001-09-18 |
2005-12-02 |
ジェネンテック・インコーポレーテッド |
腫瘍の診断及び治療のための組成物と方法
|
|
CA2460621A1
(en)
|
2001-09-19 |
2003-03-27 |
Nuvelo, Inc. |
Novel nucleic acids and polypeptides
|
|
AU2002327792A1
(en)
|
2001-09-28 |
2003-04-07 |
Bing Yang |
Diagnosis and treatment of diseases caused by mutations in cd72
|
|
AU2002362454A1
(en)
|
2001-10-03 |
2003-04-14 |
Origene Technologies, Inc. |
Regulated breast cancer genes
|
|
AU2002362436A1
(en)
|
2001-10-03 |
2003-04-14 |
Rigel Pharmaceuticals, Inc. |
Modulators of lymphocyte activation and migration
|
|
CA2842429A1
(en)
|
2001-10-19 |
2003-05-01 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of inflammatory bowel disorders
|
|
US20050123925A1
(en)
|
2002-11-15 |
2005-06-09 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
EP1525213B1
(en)
|
2001-10-24 |
2012-06-27 |
National Jewish Health |
Three-dimensional structures of tall-1 and its cognate receptors and modified proteins and methods related thereto
|
|
MXPA04003697A
(es)
|
2001-10-31 |
2005-04-08 |
Alcon Inc |
Proteinas morfogenicas de hueso (bmp), receptores de bmp y proteinas de enlace de bmp y su uso en el diagnostico y tratamiento de glaucoma.
|
|
US20030232350A1
(en)
|
2001-11-13 |
2003-12-18 |
Eos Biotechnology, Inc. |
Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer
|
|
WO2003042661A2
(en)
|
2001-11-13 |
2003-05-22 |
Protein Design Labs, Inc. |
Methods of diagnosis of cancer, compositions and methods of screening for modulators of cancer
|
|
AU2002339691A1
(en)
|
2001-11-29 |
2003-06-10 |
Genset |
Agonists and antagonists of prolixin for the treatment of metabolic disorders
|
|
AU2002349784A1
(en)
|
2001-12-03 |
2003-06-17 |
Asahi Kasei Pharma Corporation |
Nf-kappab activating genes
|
|
WO2003054152A2
(en)
|
2001-12-10 |
2003-07-03 |
Nuvelo, Inc. |
Novel nucleic acids and polypeptides
|
|
US20030134790A1
(en)
|
2002-01-11 |
2003-07-17 |
University Of Medicine And Dentistry Of New Jersey |
Bone Morphogenetic Protein-2 And Bone Morphogenetic Protein-4 In The Treatment And Diagnosis Of Cancer
|
|
US7452675B2
(en)
|
2002-01-25 |
2008-11-18 |
The Queen's Medical Center |
Methods of screening for TRPM4b modulators
|
|
EP1485130A4
(en)
|
2002-02-21 |
2006-11-22 |
Univ Duke |
REAGENTS AND THERAPEUTIC METHODS OF AUTOIMMUNE DISEASES
|
|
JP2005535290A
(ja)
|
2002-02-22 |
2005-11-24 |
ジェネンテック・インコーポレーテッド |
免疫関連疾患の治療のための組成物と方法
|
|
AU2003224638A1
(en)
|
2002-03-01 |
2003-09-16 |
Exelixis, Inc. |
PDPK1s AS MODIFIERS OF THE p53 PATHWAY AND METHODS OF USE
|
|
US20050220798A1
(en)
|
2002-06-04 |
2005-10-06 |
Reinhard Ebner |
Cancer-linked gene as target for chemotherapy
|
|
WO2003097803A2
(en)
|
2002-05-15 |
2003-11-27 |
Avalon Pharmaceuticals |
Cancer-linked gene as target for chemotherapy
|
|
EP2258712A3
(en)
|
2002-03-15 |
2011-05-04 |
Multicell Immunotherapeutics, Inc. |
Compositions and Methods to Initiate or Enhance Antibody and Major-histocompatibility Class I or Class II-restricted T Cell Responses by Using Immunomodulatory, Non-coding RNA Motifs
|
|
CA2486490A1
(en)
|
2002-03-19 |
2003-12-31 |
Curagen Corporation |
Therapeutic polypeptides, nucleic acids encoding same, and methods of use
|
|
WO2003081210A2
(en)
|
2002-03-21 |
2003-10-02 |
Sunesis Pharmaceuticals, Inc. |
Identification of kinase inhibitors
|
|
US7193069B2
(en)
|
2002-03-22 |
2007-03-20 |
Research Association For Biotechnology |
Full-length cDNA
|
|
WO2003089624A2
(en)
|
2002-03-25 |
2003-10-30 |
Uab Research Foundation |
Fc receptor homolog, reagents, and uses thereof
|
|
AU2003222103A1
(en)
|
2002-03-28 |
2003-10-13 |
Idec Pharmaceuticals Corporation |
Novel gene targets and ligands that bind thereto for treatment and diagnosis of colon carcinomas
|
|
US20030194704A1
(en)
|
2002-04-03 |
2003-10-16 |
Penn Sharron Gaynor |
Human genome-derived single exon nucleic acid probes useful for gene expression analysis two
|
|
JP2005534287A
(ja)
|
2002-04-05 |
2005-11-17 |
アジェンシス, インコーポレイテッド |
癌の処置および検出において有用な98p4b6との名称の核酸および対応するタンパク質
|
|
WO2003087768A2
(en)
|
2002-04-12 |
2003-10-23 |
Mitokor |
Targets for therapeutic intervention identified in the mitochondrial proteome
|
|
CA2481507A1
(en)
|
2002-04-16 |
2003-10-30 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
US20030224467A1
(en)
|
2002-04-17 |
2003-12-04 |
Osborne C. Kent |
AIB1 as a prognostic marker and predictor of resistance to endocrine therapy
|
|
WO2003093444A2
(en)
|
2002-05-03 |
2003-11-13 |
Incyte Corporation |
Transporters and ion channels
|
|
AU2003232453A1
(en)
|
2002-05-30 |
2003-12-19 |
David K. Bol |
Human solute carrier family 7 member 11 (hslc7a11)
|
|
CA2488441C
(en)
|
2002-06-03 |
2015-01-27 |
Genentech, Inc. |
Synthetic antibody phage libraries
|
|
WO2003101283A2
(en)
|
2002-06-04 |
2003-12-11 |
Incyte Corporation |
Diagnostics markers for lung cancer
|
|
CN100532549C
(zh)
|
2002-06-06 |
2009-08-26 |
肿瘤疗法科学股份有限公司 |
与人结肠癌相关的基因和多肽
|
|
WO2003104270A2
(en)
|
2002-06-06 |
2003-12-18 |
Ingenium Pharmaceuticals Ag |
Dudulin 2 genes, expression products, non-human animal model: uses in human hematological disease
|
|
EP1576111A4
(en)
|
2002-06-07 |
2006-10-18 |
Avalon Pharmaceuticals |
CANCER-ASSOCIATED GENE AS A TARGET FOR CHEMOTHERAPY
|
|
AU2003245441A1
(en)
|
2002-06-12 |
2003-12-31 |
Avalon Pharmaceuticals, Inc. |
Cancer-linked gene as target for chemotherapy
|
|
US20040249130A1
(en)
|
2002-06-18 |
2004-12-09 |
Martin Stanton |
Aptamer-toxin molecules and methods for using same
|
|
AU2003247576A1
(en)
|
2002-06-18 |
2003-12-31 |
Archemix Corp. |
Aptamer-toxin molecules and methods for using same
|
|
EP1539218A4
(en)
|
2002-06-20 |
2007-08-22 |
Univ California |
COMPOSITIONS AND METHODS FOR MODULATING LYMPHOCYTE ACTIVITY
|
|
EP2365004B1
(en)
|
2002-06-21 |
2016-01-06 |
Johns Hopkins University School of Medicine |
Membrane associated tumor endothelium markers
|
|
AU2003281515A1
(en)
|
2002-07-19 |
2004-02-09 |
Cellzome Ag |
Protein complexes of cellular networks underlying the development of cancer and other diseases
|
|
BR0313033A
(pt)
|
2002-07-25 |
2007-07-10 |
Genentech Inc |
anticorpos, anticorpos monoclonais, linhagens de células de hibridoma, anticorpos receptores de anti-taci isolados, anticorpos anti -taci, métodos de modulação da atividade biológica
|
|
JP2004121218A
(ja)
|
2002-08-06 |
2004-04-22 |
Jenokkusu Soyaku Kenkyusho:Kk |
気管支喘息または慢性閉塞性肺疾患の検査方法
|
|
AU2003251471A1
(en)
|
2002-08-06 |
2004-02-25 |
Bayer Healthcare Ag |
Diagnostics and therapeutics for diseases associated with human cxc chemokine receptor 5(cxcr5)
|
|
KR20050048615A
(ko)
|
2002-08-19 |
2005-05-24 |
제넨테크, 인크. |
종양의 진단 및 치료를 위한 조성물 및 방법
|
|
WO2004020583A2
(en)
|
2002-08-27 |
2004-03-11 |
Bristol-Myers Squibb Company |
Polynucleotide predictor set for identifying protein tyrosine kinase modulators
|
|
WO2004020595A2
(en)
|
2002-08-29 |
2004-03-11 |
Five Prime Therapeutics, Inc. |
Novel human polypeptides encoded by polynucleotides
|
|
AU2002951346A0
(en)
|
2002-09-05 |
2002-09-26 |
Garvan Institute Of Medical Research |
Diagnosis of ovarian cancer
|
|
CA2496888A1
(en)
|
2002-09-06 |
2004-03-18 |
Mannkind Corporation |
Epitope sequences
|
|
WO2004040000A2
(en)
|
2002-09-09 |
2004-05-13 |
Nura, Inc |
G protein coupled receptors and uses thereof
|
|
JP2004113151A
(ja)
|
2002-09-27 |
2004-04-15 |
Sankyo Co Ltd |
癌遺伝子及びその用途
|
|
CA2500978A1
(en)
|
2002-10-03 |
2004-04-15 |
Mcgill University |
Antibodies and cyclic peptides which bind cea (carcinoembryonic antigen) and their use as cancer therapeutics
|
|
AU2003288918A1
(en)
|
2002-10-04 |
2004-05-04 |
Van Andel Research Institute |
Molecular sub-classification of kidney tumors and the discovery of new diagnostic markers
|
|
US7361740B2
(en)
|
2002-10-15 |
2008-04-22 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
|
US7608429B2
(en)
|
2002-10-31 |
2009-10-27 |
Genentech, Inc. |
Methods and compositions for increasing antibody production
|
|
EP2364716A3
(en)
|
2002-11-08 |
2012-01-11 |
Genentech, Inc. |
Compositions and methods for the treatment of natural killer cell related diseases
|
|
CA2503621A1
(en)
|
2002-11-13 |
2004-05-27 |
Genentech, Inc. |
Methods and compositions for diagnosing dysplasia
|
|
DK1569685T3
(da)
|
2002-11-15 |
2012-11-12 |
Univ Colorado Regents |
Komplementmodulatorer rettet mod komplementreceptor-2
|
|
CA2505919A1
(en)
|
2002-11-15 |
2004-06-03 |
The Board Of Trustees Of The University Of Arkansas |
Ca125 gene and its use for diagnostic and therapeutic interventions
|
|
US20080213166A1
(en)
|
2002-11-20 |
2008-09-04 |
Biogen Idec Inc. |
Novel Gene Targets and Ligands that Bind Thereto for Treatment and Diagnosis of Colon Carcinomas
|
|
EP2410332A1
(en)
|
2002-11-21 |
2012-01-25 |
The University Of Utah |
Method for identifying purinergic modulators of the olfactory system
|
|
WO2004048938A2
(en)
|
2002-11-26 |
2004-06-10 |
Protein Design Labs, Inc. |
Methods of detecting soft tissue sarcoma, compositions and methods of screening for soft tissue sarcoma modulators
|
|
US20070154886A1
(en)
|
2002-12-06 |
2007-07-05 |
Macina Roberto A |
Composition, splice variants and methods relating to ovarian specific genes and proteins
|
|
JP2004198419A
(ja)
|
2002-12-13 |
2004-07-15 |
Bayer Healthcare Llc |
Timp1を用いた検出方法
|
|
CN103833854B
(zh)
|
2002-12-16 |
2017-12-12 |
健泰科生物技术公司 |
免疫球蛋白变体及其用途
|
|
JP4898120B2
(ja)
|
2002-12-20 |
2012-03-14 |
アボット バイオセラピューティクス コーポレイション |
Gpr64に対する抗体とその利用法
|
|
US20050249671A9
(en)
|
2002-12-23 |
2005-11-10 |
David Parmelee |
Neutrokine-alpha conjugate, neutrokine-alpha complex, and uses thereof
|
|
EP1597558A2
(en)
|
2003-01-08 |
2005-11-23 |
Bristol-Myers Squibb Company |
Biomarkers and methods for determining sensitivity to epidermal growth factor receptor modulators
|
|
WO2004063355A2
(en)
|
2003-01-10 |
2004-07-29 |
Protein Design Labs, Inc. |
Novel methods of diagnosis of metastatic cancer, compositions and methods of screening for modulators of matastatic cancer
|
|
US20050227301A1
(en)
|
2003-01-10 |
2005-10-13 |
Polgen |
Cell cycle progression proteins
|
|
US20040171823A1
(en)
|
2003-01-14 |
2004-09-02 |
Nadler Steven G. |
Polynucleotides and polypeptides associated with the NF-kappaB pathway
|
|
WO2004065576A2
(en)
|
2003-01-15 |
2004-08-05 |
Millennium Pharmaceuticals, Inc. |
Methods and compositions for the treatment of urological disorder using differential expressed polypeptides
|
|
US20050079574A1
(en)
|
2003-01-16 |
2005-04-14 |
Genentech, Inc. |
Synthetic antibody phage libraries
|
|
AU2004205684A1
(en)
|
2003-01-23 |
2004-08-05 |
Genentech, Inc. |
Methods for producing humanized antibodies and improving yield of antibodies or antigen binding fragments in cell culture
|
|
EP1594893A2
(en)
|
2003-02-14 |
2005-11-16 |
Sagres Discovery, Inc. |
Therapeutic targets in cancer
|
|
US20030224411A1
(en)
|
2003-03-13 |
2003-12-04 |
Stanton Lawrence W. |
Genes that are up- or down-regulated during differentiation of human embryonic stem cells
|
|
EP1608664B1
(en)
|
2003-03-31 |
2009-01-28 |
Council of Scientific and Industrial Research |
Non-cross-linking pyrrolo[2,1-c][1,4]benzodiazepines as potential antitumour agents and process thereof
|
|
GB0321295D0
(en)
|
2003-09-11 |
2003-10-15 |
Spirogen Ltd |
Synthesis of protected pyrrolobenzodiazepines
|
|
ATE516288T1
(de)
|
2003-10-22 |
2011-07-15 |
Us Gov Health & Human Serv |
Pyrrolobenzodiazepinderivate, zusammensetzungen, die diese enthalten, und damit in zusammenhang stehende verfahren
|
|
AU2005216251B2
(en)
|
2004-02-23 |
2011-03-10 |
Genentech, Inc. |
Heterocyclic self-immolative linkers and conjugates
|
|
GB0404578D0
(en)
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
GB0404577D0
(en)
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
|
JP5166861B2
(ja)
|
2004-03-09 |
2013-03-21 |
スピロゲン リミティッド |
ピロロベンゾジアゼピン
|
|
MXPA06011199A
(es)
|
2004-03-31 |
2007-04-16 |
Genentech Inc |
Anticuerpos anti-tgf-beta humanizados.
|
|
US7785903B2
(en)
|
2004-04-09 |
2010-08-31 |
Genentech, Inc. |
Variable domain library and uses
|
|
WO2005100402A1
(en)
|
2004-04-13 |
2005-10-27 |
F.Hoffmann-La Roche Ag |
Anti-p-selectin antibodies
|
|
TWI309240B
(en)
|
2004-09-17 |
2009-05-01 |
Hoffmann La Roche |
Anti-ox40l antibodies
|
|
CN101065151B
(zh)
|
2004-09-23 |
2014-12-10 |
健泰科生物技术公司 |
半胱氨酸改造的抗体和偶联物
|
|
WO2007056441A2
(en)
|
2005-11-07 |
2007-05-18 |
Genentech, Inc. |
Binding polypeptides with diversified and consensus vh/vl hypervariable sequences
|
|
WO2007064919A2
(en)
|
2005-12-02 |
2007-06-07 |
Genentech, Inc. |
Binding polypeptides with restricted diversity sequences
|
|
DK1813614T3
(da)
|
2006-01-25 |
2012-01-23 |
Sanofi Sa |
Cytotoksiske midler, der omfatter nye tomaymycinderivater
|
|
AR060871A1
(es)
|
2006-05-09 |
2008-07-16 |
Genentech Inc |
Union de polipeptidos con supercontigos optimizados
|
|
US20090182127A1
(en)
|
2006-06-22 |
2009-07-16 |
Novo Nordisk A/S |
Production of Bispecific Antibodies
|
|
ZA200900545B
(en)
|
2006-07-18 |
2010-03-31 |
Sanofi Aventis |
Antagonist antibody against EPHA2 for the treatment of cancer
|
|
EP1914242A1
(en)
|
2006-10-19 |
2008-04-23 |
Sanofi-Aventis |
Novel anti-CD38 antibodies for the treatment of cancer
|
|
CN100592373C
(zh)
|
2007-05-25 |
2010-02-24 |
群康科技(深圳)有限公司 |
液晶显示面板驱动装置及其驱动方法
|
|
SI2019104T1
(sl)
|
2007-07-19 |
2013-12-31 |
Sanofi |
Citotoksična sredstva, ki obsegajo nove tomaimicinske derivate, in njihova terapevtska uporaba
|
|
ES2563027T3
(es)
|
2008-01-07 |
2016-03-10 |
Amgen Inc. |
Método para fabricación de moléculas heterodímeras Fc de anticuerpos utilizando efectos de conducción electrostática
|
|
EP3100745B1
(en)
|
2009-02-05 |
2018-04-18 |
Immunogen, Inc. |
Novel benzodiazepine derivatives
|
|
BR112012026213B1
(pt)
|
2010-04-15 |
2021-12-28 |
Medimmune Limited |
Compostos de pirrolobenzodiazepinas, conjugado das mesmas, composição farmacêutica compreendendo o conjugado e uso do mesmo para o tratamento de uma doença proliferativa
|
|
KR101860963B1
(ko)
|
2010-04-23 |
2018-05-24 |
제넨테크, 인크. |
이종다량체 단백질의 생산
|
|
CN103313990B
(zh)
|
2010-11-17 |
2016-07-20 |
基因泰克公司 |
丙氨酰美登醇抗体偶联物
|
|
HUE041335T2
(hu)
|
2011-03-29 |
2019-05-28 |
Roche Glycart Ag |
Antitest FC-variánsok
|
|
SG11201401406YA
(en)
|
2011-10-14 |
2014-05-29 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
SI2906253T1
(sl)
*
|
2012-10-12 |
2018-11-30 |
Adc Therapeutics Sa |
Konjugati pirolobenzodiazepin-protitelo proti PSMA
|
|
US10442836B2
(en)
|
2013-08-12 |
2019-10-15 |
Genentech, Inc. |
1-(chloromethyl)-2,3-dihydro-1H-benzo[E]indole dimer antibody-drug conjugate compounds, and methods of use and treatment
|
|
WO2015052535A1
(en)
*
|
2013-10-11 |
2015-04-16 |
Spirogen Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
|
US10010624B2
(en)
*
|
2013-10-11 |
2018-07-03 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
US20160256561A1
(en)
*
|
2013-10-11 |
2016-09-08 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
EP3054985B1
(en)
*
|
2013-10-11 |
2018-12-26 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
|
GB201317982D0
(en)
*
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
|
AU2014362238A1
(en)
*
|
2013-12-13 |
2016-06-09 |
Genentech, Inc. |
Anti-CD33 antibodies and immunoconjugates
|
|
EA201691023A1
(ru)
|
2013-12-16 |
2016-10-31 |
Дженентек, Инк. |
Пептидомиметические соединения и их конъюгаты антитела с лекарственным средством
|
|
WO2015155345A1
(en)
*
|
2014-04-11 |
2015-10-15 |
Medimmune Limited |
Antibodies and antibody-drug conjugates
|
|
GB201406767D0
(en)
*
|
2014-04-15 |
2014-05-28 |
Cancer Rec Tech Ltd |
Humanized anti-Tn-MUC1 antibodies anf their conjugates
|
|
BR112016027222A2
(pt)
*
|
2014-05-22 |
2018-01-30 |
Genentech Inc |
anticorpos isolados, ácido nucleico isolado, célula hospedeira, método de produção de um anticorpo, imunoconjugado, formulação farmacêutica, métodos de tratamento de um indivíduo com um câncer, de inibição da proliferação de uma célula, de detecção de gpc3 humano e de detecção de um câncer
|
|
PE20170935A1
(es)
*
|
2014-09-12 |
2017-07-13 |
Genentech Inc |
Anticuerpos anti-her2 e inmunoconjugados
|
|
AU2015317653A1
(en)
|
2014-09-17 |
2017-04-06 |
Genentech, Inc. |
Pyrrolobenzodiazepines and antibody disulfide conjugates thereof
|
|
MA43345A
(fr)
|
2015-10-02 |
2018-08-08 |
Hoffmann La Roche |
Conjugués anticorps-médicaments de pyrrolobenzodiazépine et méthodes d'utilisation
|
|
MA43354A
(fr)
|
2015-10-16 |
2018-08-22 |
Genentech Inc |
Conjugués médicamenteux à pont disulfure encombré
|
|
GB201602359D0
(en)
*
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
|
US20200323991A1
(en)
*
|
2016-03-29 |
2020-10-15 |
Endocyte, Inc. |
Pbd conjugates for treating diseases
|
|
WO2018031662A1
(en)
|
2016-08-11 |
2018-02-15 |
Genentech, Inc. |
Pyrrolobenzodiazepine prodrugs and antibody conjugates thereof
|