DK1569685T3 - Komplementmodulatorer rettet mod komplementreceptor-2 - Google Patents
Komplementmodulatorer rettet mod komplementreceptor-2Info
- Publication number
- DK1569685T3 DK1569685T3 DK03796403.8T DK03796403T DK1569685T3 DK 1569685 T3 DK1569685 T3 DK 1569685T3 DK 03796403 T DK03796403 T DK 03796403T DK 1569685 T3 DK1569685 T3 DK 1569685T3
- Authority
- DK
- Denmark
- Prior art keywords
- complement
- receptor
- modulators targeting
- modulators
- targeting
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
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- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
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- A—HUMAN NECESSITIES
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- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Diabetes (AREA)
- Tropical Medicine & Parasitology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Pulmonology (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Cell Biology (AREA)
- Neurology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42667602P | 2002-11-15 | 2002-11-15 | |
PCT/US2003/036459 WO2004045520A2 (en) | 2002-11-15 | 2003-11-13 | Complement receptor 2 targeted complement modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1569685T3 true DK1569685T3 (da) | 2012-11-12 |
Family
ID=32326396
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK03796403.8T DK1569685T3 (da) | 2002-11-15 | 2003-11-13 | Komplementmodulatorer rettet mod komplementreceptor-2 |
Country Status (10)
Country | Link |
---|---|
US (4) | US8007804B2 (da) |
EP (2) | EP1569685B8 (da) |
JP (3) | JP4915980B2 (da) |
CN (1) | CN100594037C (da) |
AU (2) | AU2003298650B2 (da) |
CA (1) | CA2505601C (da) |
DK (1) | DK1569685T3 (da) |
ES (1) | ES2392511T3 (da) |
PT (1) | PT1569685E (da) |
WO (1) | WO2004045520A2 (da) |
Families Citing this family (126)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6820011B2 (en) | 2001-04-11 | 2004-11-16 | The Regents Of The University Of Colorado | Three-dimensional structure of complement receptor type 2 and uses thereof |
AU2003298650B2 (en) * | 2002-11-15 | 2010-03-11 | Musc Foundation For Research Development | Complement receptor 2 targeted complement modulators |
SI1725249T1 (sl) | 2003-11-06 | 2014-04-30 | Seattle Genetics, Inc. | Spojine monometilvalina, sposobne konjugacije na ligande |
US8454963B2 (en) * | 2003-11-13 | 2013-06-04 | Musc Foundation For Research Development | Tissue targeted complement modulators |
WO2005069726A2 (en) * | 2004-01-21 | 2005-08-04 | Case Western Reserve University | Hybrid and chimeric polypeptides that regulate activation of complement |
BRPI0506629A (pt) * | 2004-02-10 | 2007-05-02 | Univ Colorado | inibição do fator b, a via alternativa do sistema complemento e métodos relacionados |
EP2286844A3 (en) | 2004-06-01 | 2012-08-22 | Genentech, Inc. | Antibody-drug conjugates and methods |
US20100111856A1 (en) | 2004-09-23 | 2010-05-06 | Herman Gill | Zirconium-radiolabeled, cysteine engineered antibody conjugates |
WO2006034488A2 (en) | 2004-09-23 | 2006-03-30 | Genentech, Inc. | Cysteine engineered antibodies and conjugates |
CN103505728A (zh) * | 2005-05-26 | 2014-01-15 | 科罗拉多大学评议会法人机构 | 用于治疗外伤性脑损伤、脊髓损伤及相关病症的补体旁路抑制 |
WO2006131874A2 (en) * | 2005-06-06 | 2006-12-14 | Univ Cape Town | Methods for treatment or prophylaxis of atherosclerosis and reperfusion injury |
ES2523640T3 (es) | 2006-06-21 | 2014-11-28 | Musc Foundation For Research Development | Direccionamiento del factor H del complemento para el tratamiento de enfermedades |
US7723292B2 (en) * | 2006-09-06 | 2010-05-25 | Fernando And Anna Foundation | Compositions and methods for treating cancer |
JP2010505946A (ja) | 2006-10-10 | 2010-02-25 | アカデミシュ ジーケンハウス ビイ デ ユニヴェアズィテート ファン アムステルダム | 神経再生改善のための補体阻害 |
EP2118142A2 (en) | 2007-03-14 | 2009-11-18 | Taligen Therapeutics, Inc. | Humaneered anti-factor b antibody |
WO2008151088A2 (en) * | 2007-06-01 | 2008-12-11 | University Of Maryland, Baltimore | Immunoglobulin constant region fc receptor binding agents |
US8324182B2 (en) * | 2008-02-15 | 2012-12-04 | Tufts University | Humanized model of membrane attack complex (MAC) formation on murine retina and compositions, kits and methods for treatment of macular degeneration |
WO2009151634A1 (en) * | 2008-06-12 | 2009-12-17 | The Board Of Trustees Of The Leland Stanford Junior University | Complement inhibitory agents as therapeutics in posttraumatic and degenerative arthritis |
US8840868B2 (en) * | 2009-02-04 | 2014-09-23 | The Regents Of The University Of Colorado, A Body Corporate | Non-invasive detection of complement-mediated inflammation using CR2-targeted nanoparticles |
ME01699B (me) * | 2009-07-02 | 2014-09-20 | Musc Found For Res Dev | Metode za stimulaciju regeneracije jetre |
EP2448966B1 (en) | 2009-07-03 | 2018-11-14 | Avipep Pty Ltd | Immuno-conjugates and methods for producing them |
AU2010292172A1 (en) | 2009-09-09 | 2012-05-03 | Centrose, Llc | Extracellular targeted drug conjugates |
MX2012005151A (es) | 2009-11-05 | 2012-08-23 | Federico Ii University Of Naples | Tratamiento de hemoglobinuria nocturna paroxismica, anemias hemoliticas y estados de enfermedad que involucran hemolisis intravascular y extravascular. |
AU2010336029B2 (en) | 2009-12-23 | 2011-10-13 | Avipep Pty Ltd | Immuno-conjugates and methods for producing them 2 |
JP6148013B2 (ja) | 2010-03-05 | 2017-06-14 | リグショスピタレト | 補体活性化のキメラ抑制分子 |
PE20130342A1 (es) | 2010-04-15 | 2013-04-20 | Spirogen Sarl | Pirrolobenzodiacepinas y conjugados de las mismas |
EP3260128B1 (en) * | 2010-04-28 | 2020-07-29 | Oncolmmune, Inc. | Medical use of soluble cd24 |
US20130231464A1 (en) | 2010-04-28 | 2013-09-05 | Oncolmmune, Inc. | Methods of use of soluble cd24 for therapy of rheumatoid arthritis |
MX2012013233A (es) * | 2010-05-14 | 2013-05-20 | Univ Colorado Regents | Grupos que apuntan a receptor 2 de complemento (cr2) mejorados. |
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-
2003
- 2003-11-13 AU AU2003298650A patent/AU2003298650B2/en not_active Ceased
- 2003-11-13 PT PT03796403T patent/PT1569685E/pt unknown
- 2003-11-13 US US10/534,772 patent/US8007804B2/en active Active
- 2003-11-13 DK DK03796403.8T patent/DK1569685T3/da active
- 2003-11-13 CN CN200380108789A patent/CN100594037C/zh not_active Expired - Fee Related
- 2003-11-13 JP JP2004553695A patent/JP4915980B2/ja not_active Expired - Lifetime
- 2003-11-13 ES ES03796403T patent/ES2392511T3/es not_active Expired - Lifetime
- 2003-11-13 WO PCT/US2003/036459 patent/WO2004045520A2/en active Application Filing
- 2003-11-13 EP EP03796403A patent/EP1569685B8/en not_active Expired - Lifetime
- 2003-11-13 CA CA2505601A patent/CA2505601C/en not_active Expired - Fee Related
- 2003-11-13 EP EP20100010735 patent/EP2292259A3/en not_active Withdrawn
-
2010
- 2010-06-11 AU AU2010202455A patent/AU2010202455B2/en not_active Ceased
- 2010-09-27 JP JP2010216235A patent/JP5478449B2/ja not_active Expired - Lifetime
-
2011
- 2011-06-16 US US13/162,479 patent/US20120014952A1/en not_active Abandoned
- 2011-06-16 US US13/162,434 patent/US8540997B2/en not_active Expired - Lifetime
- 2011-06-16 US US13/162,423 patent/US20120015871A1/en not_active Abandoned
- 2011-06-28 JP JP2011143557A patent/JP2011225595A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
CN100594037C (zh) | 2010-03-17 |
EP1569685A4 (en) | 2006-08-02 |
CA2505601A1 (en) | 2004-06-03 |
EP1569685B1 (en) | 2012-08-08 |
EP1569685A2 (en) | 2005-09-07 |
CN1756560A (zh) | 2006-04-05 |
JP2011225595A (ja) | 2011-11-10 |
JP2011006478A (ja) | 2011-01-13 |
PT1569685E (pt) | 2012-11-02 |
US20120015871A1 (en) | 2012-01-19 |
JP2006512325A (ja) | 2006-04-13 |
EP1569685B8 (en) | 2012-12-05 |
ES2392511T3 (es) | 2012-12-11 |
AU2003298650B2 (en) | 2010-03-11 |
WO2004045520A2 (en) | 2004-06-03 |
WO2004045520A3 (en) | 2004-10-28 |
CA2505601C (en) | 2014-10-28 |
AU2010202455A1 (en) | 2010-07-01 |
AU2010202455B2 (en) | 2013-02-14 |
US20080267980A1 (en) | 2008-10-30 |
US20120015872A1 (en) | 2012-01-19 |
US8007804B2 (en) | 2011-08-30 |
EP2292259A3 (en) | 2011-03-23 |
US8540997B2 (en) | 2013-09-24 |
JP5478449B2 (ja) | 2014-04-23 |
EP2292259A2 (en) | 2011-03-09 |
AU2003298650A1 (en) | 2004-06-15 |
US20120014952A1 (en) | 2012-01-19 |
JP4915980B2 (ja) | 2012-04-11 |
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