JP2019532095A5 - - Google Patents
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- Publication number
- JP2019532095A5 JP2019532095A5 JP2019531514A JP2019531514A JP2019532095A5 JP 2019532095 A5 JP2019532095 A5 JP 2019532095A5 JP 2019531514 A JP2019531514 A JP 2019531514A JP 2019531514 A JP2019531514 A JP 2019531514A JP 2019532095 A5 JP2019532095 A5 JP 2019532095A5
- Authority
- JP
- Japan
- Prior art keywords
- ophthalmic
- ophthalmic preparation
- preparation according
- compound
- formulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000002360 preparation method Methods 0.000 claims 21
- -1 azole compound Chemical class 0.000 claims 7
- 238000009472 formulation Methods 0.000 claims 7
- 239000000203 mixture Substances 0.000 claims 7
- KAESVJOAVNADME-UHFFFAOYSA-N 1H-pyrrole Natural products C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 claims 5
- 239000004480 active ingredient Substances 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 4
- 239000003937 drug carrier Substances 0.000 claims 4
- 208000029515 lens disease Diseases 0.000 claims 4
- 238000013268 sustained release Methods 0.000 claims 3
- 239000012730 sustained-release form Substances 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 239000002552 dosage form Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 238000002347 injection Methods 0.000 claims 2
- 239000007924 injection Substances 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000002562 thickening agent Substances 0.000 claims 2
- BQPPJGMMIYJVBR-UHFFFAOYSA-N (10S)-3c-Acetoxy-4.4.10r.13c.14t-pentamethyl-17c-((R)-1.5-dimethyl-hexen-(4)-yl)-(5tH)-Delta8-tetradecahydro-1H-cyclopenta[a]phenanthren Natural products CC12CCC(OC(C)=O)C(C)(C)C1CCC1=C2CCC2(C)C(C(CCC=C(C)C)C)CCC21C BQPPJGMMIYJVBR-UHFFFAOYSA-N 0.000 claims 1
- CHGIKSSZNBCNDW-UHFFFAOYSA-N (3beta,5alpha)-4,4-Dimethylcholesta-8,24-dien-3-ol Natural products CC12CCC(O)C(C)(C)C1CCC1=C2CCC2(C)C(C(CCC=C(C)C)C)CCC21 CHGIKSSZNBCNDW-UHFFFAOYSA-N 0.000 claims 1
- XYTLYKGXLMKYMV-UHFFFAOYSA-N 14alpha-methylzymosterol Natural products CC12CCC(O)CC1CCC1=C2CCC2(C)C(C(CCC=C(C)C)C)CCC21C XYTLYKGXLMKYMV-UHFFFAOYSA-N 0.000 claims 1
- FPTJELQXIUUCEY-UHFFFAOYSA-N 3beta-Hydroxy-lanostan Natural products C1CC2C(C)(C)C(O)CCC2(C)C2C1C1(C)CCC(C(C)CCCC(C)C)C1(C)CC2 FPTJELQXIUUCEY-UHFFFAOYSA-N 0.000 claims 1
- 208000002177 Cataract Diseases 0.000 claims 1
- BKLIAINBCQPSOV-UHFFFAOYSA-N Gluanol Natural products CC(C)CC=CC(C)C1CCC2(C)C3=C(CCC12C)C4(C)CCC(O)C(C)(C)C4CC3 BKLIAINBCQPSOV-UHFFFAOYSA-N 0.000 claims 1
- LOPKHWOTGJIQLC-UHFFFAOYSA-N Lanosterol Natural products CC(CCC=C(C)C)C1CCC2(C)C3=C(CCC12C)C4(C)CCC(C)(O)C(C)(C)C4CC3 LOPKHWOTGJIQLC-UHFFFAOYSA-N 0.000 claims 1
- CAHGCLMLTWQZNJ-UHFFFAOYSA-N Nerifoliol Natural products CC12CCC(O)C(C)(C)C1CCC1=C2CCC2(C)C(C(CCC=C(C)C)C)CCC21C CAHGCLMLTWQZNJ-UHFFFAOYSA-N 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 150000003851 azoles Chemical class 0.000 claims 1
- 230000003796 beauty Effects 0.000 claims 1
- 230000003115 biocidal effect Effects 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- QBSJHOGDIUQWTH-UHFFFAOYSA-N dihydrolanosterol Natural products CC(C)CCCC(C)C1CCC2(C)C3=C(CCC12C)C4(C)CCC(C)(O)C(C)(C)C4CC3 QBSJHOGDIUQWTH-UHFFFAOYSA-N 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 239000003862 glucocorticoid Substances 0.000 claims 1
- 239000007943 implant Substances 0.000 claims 1
- 229940058690 lanosterol Drugs 0.000 claims 1
- 239000004005 microsphere Substances 0.000 claims 1
- 231100000344 non-irritating Toxicity 0.000 claims 1
- 239000002997 ophthalmic solution Substances 0.000 claims 1
- 229940054534 ophthalmic solution Drugs 0.000 claims 1
- 230000003204 osmotic effect Effects 0.000 claims 1
- 201000010041 presbyopia Diseases 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 230000002335 preservative effect Effects 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610717956.2A CN107397745A (zh) | 2016-08-24 | 2016-08-24 | 唑类化合物眼用制剂 |
| CN201610717956.2 | 2016-08-24 | ||
| PCT/CN2017/098662 WO2018036523A1 (zh) | 2016-08-24 | 2017-08-23 | 唑类化合物眼用制剂 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019532095A JP2019532095A (ja) | 2019-11-07 |
| JP2019532095A5 true JP2019532095A5 (enExample) | 2020-03-19 |
| JP6890794B2 JP6890794B2 (ja) | 2021-06-18 |
Family
ID=60389600
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019531514A Expired - Fee Related JP6890794B2 (ja) | 2016-08-24 | 2017-08-23 | アゾール系化合物の眼用製剤 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20190192427A1 (enExample) |
| EP (1) | EP3505170B1 (enExample) |
| JP (1) | JP6890794B2 (enExample) |
| KR (1) | KR20190052005A (enExample) |
| CN (2) | CN107397745A (enExample) |
| AU (1) | AU2017317154B2 (enExample) |
| CA (1) | CA3034766A1 (enExample) |
| EA (1) | EA201990550A1 (enExample) |
| SG (1) | SG11201901617PA (enExample) |
| WO (1) | WO2018036523A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109985071A (zh) * | 2017-12-29 | 2019-07-09 | 上海蓝木化工有限公司 | 桦褐孔菌提取物的新用途 |
| CA3110287A1 (en) * | 2018-08-28 | 2020-03-05 | Cloudbreak Therapeutics, Llc | Emulsion formulations of multikinase inhibitors |
| MX2021009520A (es) * | 2021-08-06 | 2023-02-07 | Foodvica S A De C V | Composicion oftalmica para el tratamiento de trastornos visuales. |
| CN115737654B (zh) * | 2021-09-03 | 2025-11-21 | 成都瑞沐生物医药科技有限公司 | 一种滴眼给药预防和/或治疗白内障的眼用制剂 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02290815A (ja) * | 1989-05-01 | 1990-11-30 | Santen Pharmaceut Co Ltd | 抗真菌点眼剤 |
| WO1999063968A1 (fr) * | 1998-06-10 | 1999-12-16 | Wakamoto Pharmaceutical Co., Ltd. | Preparations aqueuses contenant des medicaments faiblement solubles |
| GB0122318D0 (en) * | 2001-09-14 | 2001-11-07 | Novartis Ag | Organic compounds |
| CN100418536C (zh) * | 2005-04-06 | 2008-09-17 | 河南省眼科研究所 | 一种用于眼科的抗真菌药物组合物 |
| CN100418530C (zh) * | 2005-04-06 | 2008-09-17 | 河南省眼科研究所 | 一种酮康唑滴眼液及其制造方法 |
| US20070249546A1 (en) * | 2006-04-22 | 2007-10-25 | Sawaya Assad S | Ophthalmic and related aqueous solutions containing antifungal agents, uses therefor and methods for preparing them |
| EP2229174A1 (en) * | 2007-12-04 | 2010-09-22 | Novagali Pharma S.A. | Compositions comprising corticosteroid prodrug such as dexamethasone palmitate for the treatment of eye disorders |
| CN101766628B (zh) * | 2010-01-20 | 2012-07-04 | 广东宏盈科技有限公司 | 一种眼科外用抗细菌感染药物 |
| CN101786993A (zh) * | 2010-03-26 | 2010-07-28 | 复旦大学 | 1，2，3-三氮唑化合物及其在制备吲哚胺2，3-双加氧酶抑制剂中的用途 |
| CN104027302B (zh) * | 2013-03-07 | 2019-04-05 | 中国医药工业研究总院 | 17α-乙炔基雄甾-5-烯-3β,7β,17β-三醇眼用制剂 |
| JP2015093869A (ja) * | 2013-11-14 | 2015-05-18 | 国立大学法人東北大学 | 網膜保護薬剤、及び網膜疾患治療用徐放デバイス |
| CN103736093A (zh) * | 2013-12-27 | 2014-04-23 | 于运红 | 一种包含咪唑斯汀及甾族化合物的药物制剂 |
| US20170239273A1 (en) * | 2014-08-22 | 2017-08-24 | Kang Zhang | Compositions and methods to treat and/or prevent vision disorders of the lens of the eye |
| CA2958868A1 (en) * | 2014-08-22 | 2016-02-25 | Guangzhou Kangrui Biological Pharmaceutical Technology Co., Ltd. | Compositions and methods to treat vision disorders |
-
2016
- 2016-08-24 CN CN201610717956.2A patent/CN107397745A/zh active Pending
-
2017
- 2017-08-23 WO PCT/CN2017/098662 patent/WO2018036523A1/zh not_active Ceased
- 2017-08-23 US US16/327,238 patent/US20190192427A1/en not_active Abandoned
- 2017-08-23 SG SG11201901617PA patent/SG11201901617PA/en unknown
- 2017-08-23 JP JP2019531514A patent/JP6890794B2/ja not_active Expired - Fee Related
- 2017-08-23 CA CA3034766A patent/CA3034766A1/en not_active Abandoned
- 2017-08-23 KR KR1020197008376A patent/KR20190052005A/ko not_active Withdrawn
- 2017-08-23 AU AU2017317154A patent/AU2017317154B2/en not_active Ceased
- 2017-08-23 EP EP17842945.2A patent/EP3505170B1/en active Active
- 2017-08-23 CN CN201780051907.2A patent/CN109689049B/zh active Active
- 2017-08-23 EA EA201990550A patent/EA201990550A1/ru unknown
-
2021
- 2021-07-06 US US17/367,863 patent/US20210330586A1/en not_active Abandoned
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