EA201990550A1 - Офтальмологический препарат, включающий азоловое соединение - Google Patents
Офтальмологический препарат, включающий азоловое соединениеInfo
- Publication number
- EA201990550A1 EA201990550A1 EA201990550A EA201990550A EA201990550A1 EA 201990550 A1 EA201990550 A1 EA 201990550A1 EA 201990550 A EA201990550 A EA 201990550A EA 201990550 A EA201990550 A EA 201990550A EA 201990550 A1 EA201990550 A1 EA 201990550A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- compound
- asolic
- ophthalmic
- ophthalmic drug
- drug including
- Prior art date
Links
- 239000003732 agents acting on the eye Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 229940023490 ophthalmic product Drugs 0.000 title 1
- KAESVJOAVNADME-UHFFFAOYSA-N 1H-pyrrole Natural products C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 abstract 2
- -1 azole compound Chemical class 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610717956.2A CN107397745A (zh) | 2016-08-24 | 2016-08-24 | 唑类化合物眼用制剂 |
| PCT/CN2017/098662 WO2018036523A1 (zh) | 2016-08-24 | 2017-08-23 | 唑类化合物眼用制剂 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201990550A1 true EA201990550A1 (ru) | 2019-11-29 |
Family
ID=60389600
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201990550A EA201990550A1 (ru) | 2016-08-24 | 2017-08-23 | Офтальмологический препарат, включающий азоловое соединение |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20190192427A1 (enExample) |
| EP (1) | EP3505170B1 (enExample) |
| JP (1) | JP6890794B2 (enExample) |
| KR (1) | KR20190052005A (enExample) |
| CN (2) | CN107397745A (enExample) |
| AU (1) | AU2017317154B2 (enExample) |
| CA (1) | CA3034766A1 (enExample) |
| EA (1) | EA201990550A1 (enExample) |
| SG (1) | SG11201901617PA (enExample) |
| WO (1) | WO2018036523A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109985071A (zh) * | 2017-12-29 | 2019-07-09 | 上海蓝木化工有限公司 | 桦褐孔菌提取物的新用途 |
| US20210315815A1 (en) * | 2018-08-28 | 2021-10-14 | Cloudbreak Therapeutics, Llc | Emulsion formulations of multikinase inhibitors |
| MX2021009520A (es) * | 2021-08-06 | 2023-02-07 | Foodvica S A De C V | Composicion oftalmica para el tratamiento de trastornos visuales. |
| CN115737654B (zh) * | 2021-09-03 | 2025-11-21 | 成都瑞沐生物医药科技有限公司 | 一种滴眼给药预防和/或治疗白内障的眼用制剂 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02290815A (ja) * | 1989-05-01 | 1990-11-30 | Santen Pharmaceut Co Ltd | 抗真菌点眼剤 |
| AU4061599A (en) * | 1998-06-10 | 1999-12-30 | Wakamoto Pharmaceutical Co., Ltd. | Aqueous preparations containing hardly soluble drug |
| GB0122318D0 (en) * | 2001-09-14 | 2001-11-07 | Novartis Ag | Organic compounds |
| CN100418530C (zh) * | 2005-04-06 | 2008-09-17 | 河南省眼科研究所 | 一种酮康唑滴眼液及其制造方法 |
| CN100418536C (zh) * | 2005-04-06 | 2008-09-17 | 河南省眼科研究所 | 一种用于眼科的抗真菌药物组合物 |
| US20070249546A1 (en) * | 2006-04-22 | 2007-10-25 | Sawaya Assad S | Ophthalmic and related aqueous solutions containing antifungal agents, uses therefor and methods for preparing them |
| EP2229174A1 (en) * | 2007-12-04 | 2010-09-22 | Novagali Pharma S.A. | Compositions comprising corticosteroid prodrug such as dexamethasone palmitate for the treatment of eye disorders |
| CN101766628B (zh) * | 2010-01-20 | 2012-07-04 | 广东宏盈科技有限公司 | 一种眼科外用抗细菌感染药物 |
| CN101786993A (zh) * | 2010-03-26 | 2010-07-28 | 复旦大学 | 1，2，3-三氮唑化合物及其在制备吲哚胺2，3-双加氧酶抑制剂中的用途 |
| CN104027302B (zh) * | 2013-03-07 | 2019-04-05 | 中国医药工业研究总院 | 17α-乙炔基雄甾-5-烯-3β,7β,17β-三醇眼用制剂 |
| JP2015093869A (ja) * | 2013-11-14 | 2015-05-18 | 国立大学法人東北大学 | 網膜保護薬剤、及び網膜疾患治療用徐放デバイス |
| CN103736093A (zh) * | 2013-12-27 | 2014-04-23 | 于运红 | 一种包含咪唑斯汀及甾族化合物的药物制剂 |
| WO2016029197A1 (en) * | 2014-08-22 | 2016-02-25 | Kang Zhang | Compositions and methods to treat and/or prevent vision disorders of the lens of the eye |
| CA2958868A1 (en) * | 2014-08-22 | 2016-02-25 | Guangzhou Kangrui Biological Pharmaceutical Technology Co., Ltd. | Compositions and methods to treat vision disorders |
-
2016
- 2016-08-24 CN CN201610717956.2A patent/CN107397745A/zh active Pending
-
2017
- 2017-08-23 JP JP2019531514A patent/JP6890794B2/ja not_active Expired - Fee Related
- 2017-08-23 AU AU2017317154A patent/AU2017317154B2/en not_active Ceased
- 2017-08-23 CA CA3034766A patent/CA3034766A1/en not_active Abandoned
- 2017-08-23 SG SG11201901617PA patent/SG11201901617PA/en unknown
- 2017-08-23 KR KR1020197008376A patent/KR20190052005A/ko not_active Withdrawn
- 2017-08-23 WO PCT/CN2017/098662 patent/WO2018036523A1/zh not_active Ceased
- 2017-08-23 EA EA201990550A patent/EA201990550A1/ru unknown
- 2017-08-23 EP EP17842945.2A patent/EP3505170B1/en active Active
- 2017-08-23 US US16/327,238 patent/US20190192427A1/en not_active Abandoned
- 2017-08-23 CN CN201780051907.2A patent/CN109689049B/zh active Active
-
2021
- 2021-07-06 US US17/367,863 patent/US20210330586A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA3034766A1 (en) | 2018-03-01 |
| US20190192427A1 (en) | 2019-06-27 |
| US20210330586A1 (en) | 2021-10-28 |
| AU2017317154B2 (en) | 2020-04-30 |
| CN107397745A (zh) | 2017-11-28 |
| EP3505170A4 (en) | 2020-04-29 |
| EP3505170A1 (en) | 2019-07-03 |
| CN109689049B (zh) | 2021-04-27 |
| SG11201901617PA (en) | 2019-03-28 |
| EP3505170B1 (en) | 2021-08-11 |
| JP2019532095A (ja) | 2019-11-07 |
| KR20190052005A (ko) | 2019-05-15 |
| CN109689049A (zh) | 2019-04-26 |
| JP6890794B2 (ja) | 2021-06-18 |
| WO2018036523A1 (zh) | 2018-03-01 |
| AU2017317154A1 (en) | 2019-04-11 |
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