|
SU652180A1
(ru)
|
1975-12-16 |
1979-03-15 |
Краснодарский политехнический институт |
1(Фурил-2,)-2-(2-,, формилфурил-5,, ) этилен или его метильное производное как промежуточный продукт дл синтеза фуран-2,5-дикарбоновой кислоты и способ его получени
|
|
US5436238A
(en)
|
1992-03-12 |
1995-07-25 |
President And Fellows Of Harvard College |
Halichondrins and related compounds
|
|
US5338865A
(en)
|
1992-03-12 |
1994-08-16 |
President And Fellows Of Harvard College |
Synthesis of halichondrin B and norhalichondrin B
|
|
GB9206244D0
(en)
|
1992-03-23 |
1992-05-06 |
Pharma Mar Sa |
Cytotoxic compound from a marine sponge
|
|
TW255880B
(enExample)
|
1992-09-09 |
1995-09-01 |
Hoechst Ag |
|
|
WO1998009942A1
(en)
|
1996-09-06 |
1998-03-12 |
Eli Lilly And Company |
Catalytic selective sulfonylation process
|
|
US6870058B2
(en)
|
1996-12-03 |
2005-03-22 |
The Trustees Of The University Of Pennsylvania |
Compounds which mimic the chemical and biological properties of discodermolide
|
|
US6653341B1
(en)
|
1998-06-17 |
2003-11-25 |
Eisai Co., Ltd. |
Methods and compositions for use in treating cancer
|
|
US8097648B2
(en)
|
1998-06-17 |
2012-01-17 |
Eisai R&D Management Co., Ltd. |
Methods and compositions for use in treating cancer
|
|
CA2632433C
(en)
|
1998-06-17 |
2012-02-07 |
Eisai R & D Management Co., Ltd. |
Methods for preparing macrocyclic analogs and intermediates for preparing same
|
|
DE10106647A1
(de)
|
2001-02-12 |
2002-08-22 |
Univ Hannover |
Ratjadon-Derivate zum Hemmen des Zellwachstums
|
|
KR101434673B1
(ko)
|
2004-06-03 |
2014-08-26 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
할리콘드린 ｂ 유사체의 제조를 위한 중간체
|
|
US20060045846A1
(en)
|
2004-08-30 |
2006-03-02 |
Horstmann Thomas E |
Reagents and methods for labeling terminal olefins
|
|
JP2008522623A
(ja)
|
2004-12-09 |
2008-07-03 |
エーザイ株式会社 |
ハリコンドリンｂアナログを使用した癌治療でのチューブリンアイソタイプのスクリーニング
|
|
EP1940758B1
(en)
|
2005-09-26 |
2012-11-28 |
Symrise AG |
Intramolecular prins reaction
|
|
WO2008010776A1
(en)
|
2006-07-21 |
2008-01-24 |
Agency For Science, Technology And Research |
Aigialomycin d and derivatives thereof and their use in treating cancer or malaria or a microbial infection
|
|
JPWO2009014105A1
(ja)
|
2007-07-20 |
2010-10-07 |
株式会社山田養蜂場本社 |
新規カルボン酸およびそれを有効成分とする抗うつ用組成物
|
|
EP2578576B9
(en)
|
2007-10-03 |
2016-09-14 |
Eisai R&D Management Co., Ltd. |
Intermediates for the synthesis of halichondrin B analogs
|
|
CN101910180A
(zh)
|
2007-11-16 |
2010-12-08 |
卫材R&D管理有限公司 |
用于软海绵素b类似物合成的新颖中间体和用于该中间体的新颖脱磺酰化反应
|
|
RU2517167C2
(ru)
|
2008-04-04 |
2014-05-27 |
Эйсай Ар Энд Ди Менеджмент Ко., Лтд. |
Аналоги галихондрина в
|
|
JP5371091B2
(ja)
|
2009-01-23 |
2013-12-18 |
三菱レイヨン株式会社 |
モノスルホン酸エステルの製造方法
|
|
US8203010B2
(en)
|
2010-01-26 |
2012-06-19 |
Eisai R&D Management Co., Ltd. |
Compounds useful in the synthesis of halichondrin B analogs
|
|
WO2012147900A1
(en)
*
|
2011-04-28 |
2012-11-01 |
Eisai R&D Management Co., Ltd. |
Microreactor process for halichondrin b analog synthesis
|
|
CA2857385A1
(en)
|
2011-11-30 |
2013-06-06 |
Alphora Research Inc. |
Process for preparation of (3r)-2,4-di-leaving group-3-methylbut-1-ene
|
|
CN104334562A
(zh)
|
2012-03-30 |
2015-02-04 |
阿方拉研究股份有限公司 |
用于制备软海绵素b的大环c1-酮类似物的合成方法及其中有用的中间体
|
|
WO2015000070A1
(en)
|
2013-07-03 |
2015-01-08 |
Alphora Research Inc. |
Synthetic process for preparation of macrocyclic c1-keto analogs of halichondrin b and intermediates useful therein including intermediates containing -so2-(p-tolyl) groups
|
|
CA2929084C
(en)
|
2013-11-04 |
2022-01-11 |
Eisai R&D Management Co., Ltd. |
Macrocyclization reactions and intermediates and other fragments useful in the synthesis of analogs of halichondrin b
|
|
BR112016012237B1
(pt)
|
2013-12-06 |
2023-02-07 |
Eisai R&D Management Co., Ltd |
Métodos úteis na síntese de análogos de halicondrina b
|
|
US10208058B2
(en)
|
2014-09-09 |
2019-02-19 |
Cipla Limited |
Process for the preparation of macrocyclic ketone analogs of halichondrin B or pharmaceutically acceptable salts and intermediates thereof
|
|
MX392296B
(es)
|
2015-05-07 |
2025-03-24 |
Eisai R&D Man Co Ltd |
Reacciones de macrociclizacion e intermediarios y otros fragmentos utiles en la sintesis de macrolidos de halicondrina.
|
|
US11136335B2
(en)
|
2016-06-30 |
2021-10-05 |
Eisai R&D Management Co., Ltd. |
Prins reaction and intermediates useful in the synthesis of halichondrin macrolides and analogs thereof
|
|
WO2018217894A1
(en)
|
2017-05-24 |
2018-11-29 |
Eisai R&D Management Co., Ltd. |
Fluorine-labelled halichondrin derivatives and related methods of synthesis
|
|
MX2020006945A
(es)
|
2018-01-03 |
2020-11-09 |
Eisai R&D Man Co Ltd |
Reaccion de prins y compuestos utiles en la sintesis de macrolidos de halicondrina y analogos de los mismos.
|